Synthesis and in vitro antitumor activity of substituted anthracene-1,4-diones

Tetrahedron

Volumn 60, Issue 45, 2004, Pages 10155-10163

  Hua, Duy H ^a   Lou, Kaiyan ^a   Havens, Josh ^a   Perchellet, Elisabeth M ^a   Wang, Yang ^a   Perchellet, Jean Pierre ^a   Iwamoto, Takeo ^a  

^a KANSAS STATE UNIVERSITY   (United States)

Author keywords

6 Bromomethylanthracene 1,4 dione; Antitumor activity; Human HL 60 tumor cell; L1210 leukemic cell; Phosphate ester pro drug; Substituted anthracene 1,4 diones

Indexed keywords

(1,4 DIOXO 1,4 DIHYDROANTHRACENYL)METHYL DI TERT BUTYL PHOSPHATE; 1,4 ANTHRACENEDIONE; 1,4 BENZOQUINONE; 2 (METHYLAMINO) 1,4 ANTHRACENEDIONE; 2 (METHYLAMINO) 6,7 DICHLORO 1,4 ANTHRACENEDIONE; 2 BROMO 6 METHYL 1,4 ANTHRACENEDIONE; 2 BROMO 7 METHYL 1,4 ANTHRACENEDIONE; 5,8 DIOXO 5,8 DIHYDRO 2 ANTHRACENYLMETHYL 1,3,4,5 TETRAHYDROXYCYCLOHEXANE CARBOXYLATE; 5,8 DIOXO 5,8 DIHYDROXYANTHRACENE 2 CARBOXYLIC ACID; 6 BROMOMETHYL 1,4 ANTHRACENEDIONE; 6 FORMYL 1,4 ANTHRACENEDIONE; 6 FORMYL 1,5 ANTHRACENEDIONE; 6 HYDROXY 1,4 ANTHRACENEDIONE; 6 METHYL 1,4 ANTHRACENEDIONE; 6 METHYL 1,4 DIHYDROXYANTHRAQUINONE; 6,7 DICHLORO 1,4 ANTHRACENEDIONE; 6,7 DICHLORO 1,4 DIHYDROXY 9,10 ANTHRAQUINONE; ALCOHOL; ALDEHYDE; ALKYL GROUP; ANTHRACENE DERIVATIVE; BROMIDE; DAUNORUBICIN; N [(1,4 DIOXO 1,4 DIHYDROANTHRACENYL)METHYL] 2 AMINO 2 DEOXY 1,3,4,6 TETRA O ACETYL BETA DEXTRO GLUCOPYRANOSE; N [(1,4 DIOXO 1,4 DIHYDROANTHRACENYL)METHYLIDENE] 2 AMINO 2 DEOXY 1,3,4,6 TETRA O ACETYL BETA DEXTRO GLUCOPYRANOSE; ORGANOPHOSPHATE; PRODRUG; UNCLASSIFIED DRUG; WATER;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BROMINATION; CANCER INHIBITION; CELL VIABILITY; CHEMICAL MODIFICATION; CHEMICAL REACTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSTASIS; CYTOTOXICITY; DRUG MECHANISM; DRUG POTENCY; DRUG SCREENING; DRUG SENSITIVITY; DRUG SYNTHESIS; DRUG TARGETING; FRIEDEL CRAFTS REACTION; HEALTH CARE ORGANIZATION; HUMAN; HUMAN CELL; HYDROLYSIS; IN VITRO STUDY; INHIBITION KINETICS; LEUKEMIA CELL; MOLECULAR MECHANICS; MOUSE; NONHUMAN; OXIDATION; PRIORITY JOURNAL; REACTION ANALYSIS; SOLUBILITY; TUMOR CELL; TUMOR CELL LINE;

MURINAE;

EID: 4644344470     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2004.09.026     Document Type: Article

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