Tumor necrosis factor-α-238G>A promoter polymorphism is associated with increased risk of new hemorrhage in the natural course of patients with brain arteriovenous malformations

Stroke

Volumn 37, Issue 1, 2006, Pages 231-234

  Achrol, Achal S ^a   Pawlikowska, Ludmila ^b   McCulloch, Charles E ^a   Poon, K Y Trudy ^a   Ha, Connie ^b   Zaroff, Jonathan G ^a   Johnston, S Claiborne ^a   Lee, Chanhung ^a   Lawton, Michael T ^a   Sidney, Stephen ^c   Marchuk, Douglas A ^d   Kwok, Pui Yan ^b   Young, William L ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c DIVISION OF RESEARCH   (United States)

^d DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Cerebral hemorrhage; Genetics; Vascular malformations

Indexed keywords

ADENINE; CYTOKINE; CYTOSINE; GUANINE; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGE; ARTICLE; BRAIN ARTERIOVENOUS MALFORMATION; BRAIN HEMORRHAGE; CHI SQUARE TEST; CLINICAL FEATURE; DISEASE COURSE; ETHNOLOGY; FEMALE; GENETIC ASSOCIATION; GENOTYPE; HUMAN; INFLAMMATION; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROMOTER REGION; PROPORTIONAL HAZARDS MODEL; RISK; SINGLE NUCLEOTIDE POLYMORPHISM; ARTERIOVENOUS MALFORMATION; BLEEDING; BRAIN; GENETICS; HAPLOTYPE; MIDDLE AGED; PATHOLOGY; STATISTICAL MODEL; TIME;

ADULT; ARTERIOVENOUS MALFORMATIONS; BRAIN; FEMALE; GENOTYPE; HAPLOTYPES; HEMORRHAGE; HUMANS; INTERLEUKIN-6; MALE; MIDDLE AGED; MODELS, STATISTICAL; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS (GENETICS); PROPORTIONAL HAZARDS MODELS; RISK; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33644878489     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.STR.0000195133.98378.4b     Document Type: Article

References (7)

1. Pawlikowska L, Tran MN, Achrol AS, McCulloch CE, Ha C, Lind DL, Hashimoto T, Zaroff J, Lawton MT, Marchuk DA, Kwok P-Y, Young WL. Polymorphisms in genes involved in inflammatory and angiogenic pathways and the risk of hemorrhagic presentation of brain arteriovenous malformations. Stroke. 2004;35:2294-2300.
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6. Hashimoto T, Wen G, Lawton MT, Boudreau NJ, Bollen AW, Yang GY, Barbaro NM, Higashida RT, Dowd CF, Halbach VV, Young WL. Abnormal expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in brain arteriovenous malformations. Stroke. 2003;34:925-931.
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