-
1
-
-
9144226837
-
A Phase II trial of aprinocarsen, an antisense oligonucleotide inhibitor of protein kinase Cα, administered as a 21-day infusion to patients with advanced ovarian carcinoma
-
Advani R., Peethambaram P., Lum B.L., Fisher G.A., Hartmann L., Long H.J., Halsey J., Holmlund J.T., Dorr A., and Sikic B.I. A Phase II trial of aprinocarsen, an antisense oligonucleotide inhibitor of protein kinase Cα, administered as a 21-day infusion to patients with advanced ovarian carcinoma. Cancer 100 (2004) 321-326
-
(2004)
Cancer
, vol.100
, pp. 321-326
-
-
Advani, R.1
Peethambaram, P.2
Lum, B.L.3
Fisher, G.A.4
Hartmann, L.5
Long, H.J.6
Halsey, J.7
Holmlund, J.T.8
Dorr, A.9
Sikic, B.I.10
-
2
-
-
33646816025
-
Bisphosphonate induces apoptosis and inhibits pro-osteoclastic gene expression in prostate cancer cells
-
Asahi H., Mizokami A., Miwa S., Keller E.T., Koshida K., and Namiki M. Bisphosphonate induces apoptosis and inhibits pro-osteoclastic gene expression in prostate cancer cells. Int. J. Urol. 13 (2006) 593-600
-
(2006)
Int. J. Urol.
, vol.13
, pp. 593-600
-
-
Asahi, H.1
Mizokami, A.2
Miwa, S.3
Keller, E.T.4
Koshida, K.5
Namiki, M.6
-
3
-
-
0034634443
-
Further evidence that 3-phosphoinositide-dependent protein kinase-1 (PDK1) is required for the stability and phosphorylation of protein kinase C (PKC) isoforms
-
Balendran A., Hare G.R., Kieloch A., Williams M.R., and Alessi D.R. Further evidence that 3-phosphoinositide-dependent protein kinase-1 (PDK1) is required for the stability and phosphorylation of protein kinase C (PKC) isoforms. FEBS Lett. 484 (2000) 217-223
-
(2000)
FEBS Lett.
, vol.484
, pp. 217-223
-
-
Balendran, A.1
Hare, G.R.2
Kieloch, A.3
Williams, M.R.4
Alessi, D.R.5
-
4
-
-
3042753807
-
MAPK and JNK transduction pathways can phosphorylate Sp1 to activate the uPA minimal promoter element and endogenous gene transcription
-
Benasciutti E., Pagès G., Kenzior O., Folk W., Blasi F., and Crippa M.P. MAPK and JNK transduction pathways can phosphorylate Sp1 to activate the uPA minimal promoter element and endogenous gene transcription. Blood 104 (2004) 256-262
-
(2004)
Blood
, vol.104
, pp. 256-262
-
-
Benasciutti, E.1
Pagès, G.2
Kenzior, O.3
Folk, W.4
Blasi, F.5
Crippa, M.P.6
-
5
-
-
0034214362
-
Bisphosphonates inhibit breast and prostate carcinoma cell invasion, an early event in the formation of bone metastases
-
Boissier S., Ferreras M., Peyruchaud O., Magnetto S., Ebetino F.H., Colombel M., Delmas P., Delaisse J.M., and Clezardin P. Bisphosphonates inhibit breast and prostate carcinoma cell invasion, an early event in the formation of bone metastases. Cancer Res. 60 (2000) 2949-2954
-
(2000)
Cancer Res.
, vol.60
, pp. 2949-2954
-
-
Boissier, S.1
Ferreras, M.2
Peyruchaud, O.3
Magnetto, S.4
Ebetino, F.H.5
Colombel, M.6
Delmas, P.7
Delaisse, J.M.8
Clezardin, P.9
-
6
-
-
0031038588
-
Role of diacylglycerol-regulated protein kinase C isotypes in growth factor activation of the Raf-1 protein kinase
-
Cai H., Smola U., Wixler V., Eisenmann-Tappe I., Diaz-Meco M.T., Moscat J., Rapp U., and Cooper G.M. Role of diacylglycerol-regulated protein kinase C isotypes in growth factor activation of the Raf-1 protein kinase. Mol. Cell. Biol. 17 (1997) 732-741
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 732-741
-
-
Cai, H.1
Smola, U.2
Wixler, V.3
Eisenmann-Tappe, I.4
Diaz-Meco, M.T.5
Moscat, J.6
Rapp, U.7
Cooper, G.M.8
-
7
-
-
0020326790
-
Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters
-
Castagna M., Takai Y., Kaibuchi K., Sano K., Kikkawa U., and Nishizuka Y. Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters. J. Biol. Chem. 257 (1982) 7847-7851
-
(1982)
J. Biol. Chem.
, vol.257
, pp. 7847-7851
-
-
Castagna, M.1
Takai, Y.2
Kaibuchi, K.3
Sano, K.4
Kikkawa, U.5
Nishizuka, Y.6
-
8
-
-
0032894014
-
Protein kinase C isoenzyme patterns characteristically modulated in early prostate cancer
-
Cornford P., Evans J., Dodson A., Parsons K., Woolfenden A., Neoptolemos J., and Foster C.S. Protein kinase C isoenzyme patterns characteristically modulated in early prostate cancer. Am. J. Pathol. 154 (1999) 137-144
-
(1999)
Am. J. Pathol.
, vol.154
, pp. 137-144
-
-
Cornford, P.1
Evans, J.2
Dodson, A.3
Parsons, K.4
Woolfenden, A.5
Neoptolemos, J.6
Foster, C.S.7
-
9
-
-
0032468984
-
Bisphosphonates: mechanisms of action
-
Fleisch H. Bisphosphonates: mechanisms of action. Endocr. Rev. 19 (1998) 80-100
-
(1998)
Endocr. Rev.
, vol.19
, pp. 80-100
-
-
Fleisch, H.1
-
10
-
-
0036148405
-
Development of bisphosphonates
-
Fleisch H. Development of bisphosphonates. Breast Cancer Res. 4 (2002) 30-34
-
(2002)
Breast Cancer Res.
, vol.4
, pp. 30-34
-
-
Fleisch, H.1
-
11
-
-
0014684354
-
Diphosphonates inhibit hydroxyapatite dissolution in vitro and bone resorption in tissue culture and in vivo
-
Fleisch H., Russell R.G., and Francis M.D. Diphosphonates inhibit hydroxyapatite dissolution in vitro and bone resorption in tissue culture and in vivo. Science 165 (1969) 1262-1264
-
(1969)
Science
, vol.165
, pp. 1262-1264
-
-
Fleisch, H.1
Russell, R.G.2
Francis, M.D.3
-
12
-
-
60549097419
-
Endocrine therapy plus zoledronic acid in premenopausal breast cancer
-
Gnant M., Mlineritsch B., Schippinger W., Luschin-Ebengreuth G., Postlberger S., Menzel C., Jakesz R., Seifert M., Hubalek M., Bjelic-Radisic V., Samonigg H., Tausch C., Eidtmann H., Steger G., Kwasny W., Dubsky P., Fridrik M., Fitzal F., Stierer M., Rucklinger E., Greil R., and Marth C. Endocrine therapy plus zoledronic acid in premenopausal breast cancer. N. Engl. J. Med. 360 (2009) 679-691
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 679-691
-
-
Gnant, M.1
Mlineritsch, B.2
Schippinger, W.3
Luschin-Ebengreuth, G.4
Postlberger, S.5
Menzel, C.6
Jakesz, R.7
Seifert, M.8
Hubalek, M.9
Bjelic-Radisic, V.10
Samonigg, H.11
Tausch, C.12
Eidtmann, H.13
Steger, G.14
Kwasny, W.15
Dubsky, P.16
Fridrik, M.17
Fitzal, F.18
Stierer, M.19
Rucklinger, E.20
Greil, R.21
Marth, C.22
more..
-
13
-
-
40149093563
-
Protein kinase C synergistically stimulates tumor necrosis factor-α-induced secretion of urokinase-type plasminogen activator in human dental pulp cells
-
Hashizume H., Kamio N., Nakao S., Matsushima K., and Sugiya H. Protein kinase C synergistically stimulates tumor necrosis factor-α-induced secretion of urokinase-type plasminogen activator in human dental pulp cells. J. Physiol. Sci. 58 (2008) 83-86
-
(2008)
J. Physiol. Sci.
, vol.58
, pp. 83-86
-
-
Hashizume, H.1
Kamio, N.2
Nakao, S.3
Matsushima, K.4
Sugiya, H.5
-
14
-
-
0034906033
-
Phosphatidylserine induces apoptosis in adherent cells
-
Iguchi K., Hirano K., Hamatake M., and Ishida R. Phosphatidylserine induces apoptosis in adherent cells. Apoptosis 6 (2001) 263-268
-
(2001)
Apoptosis
, vol.6
, pp. 263-268
-
-
Iguchi, K.1
Hirano, K.2
Hamatake, M.3
Ishida, R.4
-
15
-
-
33746687894
-
Inhibition of caveolin-1 expression by incadronate in PC-3 prostate cells
-
Iguchi K., Matsunaga S., Nakano T., Usui S., and Hirano K. Inhibition of caveolin-1 expression by incadronate in PC-3 prostate cells. Anticancer Res. 26 (2006) 2977-2981
-
(2006)
Anticancer Res.
, vol.26
, pp. 2977-2981
-
-
Iguchi, K.1
Matsunaga, S.2
Nakano, T.3
Usui, S.4
Hirano, K.5
-
16
-
-
33646827825
-
Incadronate inhibits aminopeptidase N expression in prostatic PC-3 cells
-
Iguchi K., Nakano T., Usui S., and Hirano K. Incadronate inhibits aminopeptidase N expression in prostatic PC-3 cells. Cancer Lett. 237 (2006) 223-233
-
(2006)
Cancer Lett.
, vol.237
, pp. 223-233
-
-
Iguchi, K.1
Nakano, T.2
Usui, S.3
Hirano, K.4
-
17
-
-
37549001685
-
Pamidronate down-regulates urokinase-type plasminogen activator expression in PC-3 prostate cancer cells
-
Iguchi K., Tatsuda Y., Usui S., and Hirano K. Pamidronate down-regulates urokinase-type plasminogen activator expression in PC-3 prostate cancer cells. Anticancer Res. 27 (2007) 3843-3848
-
(2007)
Anticancer Res.
, vol.27
, pp. 3843-3848
-
-
Iguchi, K.1
Tatsuda, Y.2
Usui, S.3
Hirano, K.4
-
18
-
-
2542534542
-
Protein kinase C-α in prostate cancer
-
Lahn M., Sundell K., Gleave M., Ladan F., Su C., Li S., Ma D., Paterson B.M., and Bumol T.F. Protein kinase C-α in prostate cancer. BJU Int. 93 (2004) 1076-1081
-
(2004)
BJU Int.
, vol.93
, pp. 1076-1081
-
-
Lahn, M.1
Sundell, K.2
Gleave, M.3
Ladan, F.4
Su, C.5
Li, S.6
Ma, D.7
Paterson, B.M.8
Bumol, T.F.9
-
19
-
-
0035866791
-
Bisphosphonate treatment inhibits the growth of prostate cancer cells
-
Lee M.V., Fong E.M., Singer F.R., and Guenette R.S. Bisphosphonate treatment inhibits the growth of prostate cancer cells. Cancer Res. 61 (2001) 2602-2608
-
(2001)
Cancer Res.
, vol.61
, pp. 2602-2608
-
-
Lee, M.V.1
Fong, E.M.2
Singer, F.R.3
Guenette, R.S.4
-
20
-
-
34250902930
-
Targeting the protein kinase C family: are we there yet?
-
Mackay H.J., and Twelves C.J. Targeting the protein kinase C family: are we there yet?. Nat. Rev. Cancer 7 (2007) 554-562
-
(2007)
Nat. Rev. Cancer
, vol.7
, pp. 554-562
-
-
Mackay, H.J.1
Twelves, C.J.2
-
21
-
-
0030581475
-
Cell signalling. Raf gets it together
-
Marshall C.J. Cell signalling. Raf gets it together. Nature 383 (1996) 127-128
-
(1996)
Nature
, vol.383
, pp. 127-128
-
-
Marshall, C.J.1
-
22
-
-
34247128396
-
Incadronate induces cell detachment and apoptosis in prostatic PC-3 cells
-
Matsunaga S., Iguchi K., Usui S., and Hirano K. Incadronate induces cell detachment and apoptosis in prostatic PC-3 cells. Anticancer Res. 27 (2007) 927-932
-
(2007)
Anticancer Res.
, vol.27
, pp. 927-932
-
-
Matsunaga, S.1
Iguchi, K.2
Usui, S.3
Hirano, K.4
-
23
-
-
0036855463
-
Protein kinase Cα (PKCα): regulation and biological function
-
Nakashima S. Protein kinase Cα (PKCα): regulation and biological function. J. Biol. Chem. 132 (2002) 669-675
-
(2002)
J. Biol. Chem.
, vol.132
, pp. 669-675
-
-
Nakashima, S.1
-
24
-
-
0141783652
-
A new bisphosphonate, YM529 induces apoptosis in HL60 cells by decreasing phosphorylation of single survival signal ERK
-
Nishida S., Fujii Y., Yoshioka S., Kikuichi S., Tsubaki M., and Irimajiri K. A new bisphosphonate, YM529 induces apoptosis in HL60 cells by decreasing phosphorylation of single survival signal ERK. Life Sci. 73 (2003) 2655-2664
-
(2003)
Life Sci.
, vol.73
, pp. 2655-2664
-
-
Nishida, S.1
Fujii, Y.2
Yoshioka, S.3
Kikuichi, S.4
Tsubaki, M.5
Irimajiri, K.6
-
25
-
-
0037664952
-
Nitrogen containing bisphosphonates induce apoptosis and inhibit the mevalonate pathway, impairing Ras membrane localization in prostate cancer cells
-
Oades G.M., Senaratne S.G., Clarke I.A., Kirby R.S., and Colston K.W. Nitrogen containing bisphosphonates induce apoptosis and inhibit the mevalonate pathway, impairing Ras membrane localization in prostate cancer cells. J. Urol. 170 (2003) 246-252
-
(2003)
J. Urol.
, vol.170
, pp. 246-252
-
-
Oades, G.M.1
Senaratne, S.G.2
Clarke, I.A.3
Kirby, R.S.4
Colston, K.W.5
-
26
-
-
33645453677
-
Phase III study of gemcitabine and cisplatin with or without aprinocarsen, a protein kinase C-alpha antisense oligonucleotide, in patients with advanced-stage non-small-cell lung cancer
-
Paz-Ares L., Douillard J.Y., Koralewski P., Manegold C., Smit E.F., Reyes J.M., Chang G.C., John W.J., Peterson P.M., Obasaju C.K., Lahn M., and Gandara D.R. Phase III study of gemcitabine and cisplatin with or without aprinocarsen, a protein kinase C-alpha antisense oligonucleotide, in patients with advanced-stage non-small-cell lung cancer. J. Clin. Oncol. 24 (2006) 1428-1434
-
(2006)
J. Clin. Oncol.
, vol.24
, pp. 1428-1434
-
-
Paz-Ares, L.1
Douillard, J.Y.2
Koralewski, P.3
Manegold, C.4
Smit, E.F.5
Reyes, J.M.6
Chang, G.C.7
John, W.J.8
Peterson, P.M.9
Obasaju, C.K.10
Lahn, M.11
Gandara, D.R.12
-
27
-
-
0029834880
-
Persistent membrane translocation of protein kinase C α during 12-0-tetradecanoylphorbol-13-acetate-induced apoptosis of LNCaP human prostate cancer cells
-
Powell C.T., Brittis N.J., Stec D., Hug H., Heston W.D., and Fair W.R. Persistent membrane translocation of protein kinase C α during 12-0-tetradecanoylphorbol-13-acetate-induced apoptosis of LNCaP human prostate cancer cells. Cell Growth Differ. 7 (1996) 419-428
-
(1996)
Cell Growth Differ.
, vol.7
, pp. 419-428
-
-
Powell, C.T.1
Brittis, N.J.2
Stec, D.3
Hug, H.4
Heston, W.D.5
Fair, W.R.6
-
28
-
-
27744435789
-
RNA interference-directed knockdown of urokinase plasminogen activator and urokinase plasminogen activator receptor inhibits prostate cancer cell invasion, survival, and tumorigenicity in vivo
-
Pulukuri S.M., Gondi C.S., Lakka S.S., Jutla A., Estes N., Gujrati M., and Rao J.S. RNA interference-directed knockdown of urokinase plasminogen activator and urokinase plasminogen activator receptor inhibits prostate cancer cell invasion, survival, and tumorigenicity in vivo. J. Biol. Chem. 280 (2005) 36529-36540
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 36529-36540
-
-
Pulukuri, S.M.1
Gondi, C.S.2
Lakka, S.S.3
Jutla, A.4
Estes, N.5
Gujrati, M.6
Rao, J.S.7
-
29
-
-
0035135687
-
Nitrogen-bisphosphonates block retinoblastoma phosphorylation and cell growth by inhibiting the cholesterol biosynthetic pathway in a keratinocyte model for esophageal irritation
-
Reszka A.A., Halasy-Nagy J., and Rodan G.A. Nitrogen-bisphosphonates block retinoblastoma phosphorylation and cell growth by inhibiting the cholesterol biosynthetic pathway in a keratinocyte model for esophageal irritation. Mol. Pharmacol. 59 (2001) 193-202
-
(2001)
Mol. Pharmacol.
, vol.59
, pp. 193-202
-
-
Reszka, A.A.1
Halasy-Nagy, J.2
Rodan, G.A.3
-
30
-
-
33645962526
-
Phase II study of PKC-α antisense oligonucleotide aprinocarsen in combination with gemcitabine and carboplatin in patients with advanced non-small cell lung cancer
-
Ritch P., Rudin C.M., Bitran J.D., Edelman M.J., Makalinao A., Irwin D., Lilenbaum R., Peterson P., and John W.J. Phase II study of PKC-α antisense oligonucleotide aprinocarsen in combination with gemcitabine and carboplatin in patients with advanced non-small cell lung cancer. Lung Cancer 52 (2006) 173-180
-
(2006)
Lung Cancer
, vol.52
, pp. 173-180
-
-
Ritch, P.1
Rudin, C.M.2
Bitran, J.D.3
Edelman, M.J.4
Makalinao, A.5
Irwin, D.6
Lilenbaum, R.7
Peterson, P.8
John, W.J.9
-
31
-
-
36549072502
-
Bisphosphonates: an update on mechanisms of action and how these relate to clinical efficacy
-
Russell R.G., Xia Z., Dunford J.E., Oppermann U., Kwaasi A., Hulley P.A., Kavanagh K.L., Triffitt J.T., Lundy M.W., Phipps R.J., Barnett B.L., Coxon F.P., Rogers M.J., Watts N.B., and Ebetino F.H. Bisphosphonates: an update on mechanisms of action and how these relate to clinical efficacy. Ann. N. Y. Acad. Sci. 1117 (2007) 209-257
-
(2007)
Ann. N. Y. Acad. Sci.
, vol.1117
, pp. 209-257
-
-
Russell, R.G.1
Xia, Z.2
Dunford, J.E.3
Oppermann, U.4
Kwaasi, A.5
Hulley, P.A.6
Kavanagh, K.L.7
Triffitt, J.T.8
Lundy, M.W.9
Phipps, R.J.10
Barnett, B.L.11
Coxon, F.P.12
Rogers, M.J.13
Watts, N.B.14
Ebetino, F.H.15
-
32
-
-
0032566717
-
A functional role for mitochondrial protein kinase Cα in Bcl2 phosphorylation and suppression of apoptosis
-
Ruvolo P.P., Deng X., Carr B.K., and May W.S. A functional role for mitochondrial protein kinase Cα in Bcl2 phosphorylation and suppression of apoptosis. J. Biol. Chem. 273 (1998) 25436-25442
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 25436-25442
-
-
Ruvolo, P.P.1
Deng, X.2
Carr, B.K.3
May, W.S.4
-
33
-
-
0026320852
-
Bisphosphonate action. Alendronate localization in rat bone and effects on osteoclast ultrastructure
-
Sato M., Grasser W., Endo N., Akins R., Simmons H., Thompson D.D., Golub E., and Rodan G.A. Bisphosphonate action. Alendronate localization in rat bone and effects on osteoclast ultrastructure. J. Clin. Invest. 88 (1991) 2095-2105
-
(1991)
J. Clin. Invest.
, vol.88
, pp. 2095-2105
-
-
Sato, M.1
Grasser, W.2
Endo, N.3
Akins, R.4
Simmons, H.5
Thompson, D.D.6
Golub, E.7
Rodan, G.A.8
-
34
-
-
0036827799
-
Alendronate inhibits lysophosphatidic acid-induced migration of human ovarian cancer cells by attenuating the activation of Rho
-
Sawada K., Morishige K., Tahara M., Kawagishi R., Ikebuchi Y., Tasaka K., and Murata Y. Alendronate inhibits lysophosphatidic acid-induced migration of human ovarian cancer cells by attenuating the activation of Rho. Cancer Res. 62 (2002) 6015-6020
-
(2002)
Cancer Res.
, vol.62
, pp. 6015-6020
-
-
Sawada, K.1
Morishige, K.2
Tahara, M.3
Kawagishi, R.4
Ikebuchi, Y.5
Tasaka, K.6
Murata, Y.7
-
35
-
-
4043153532
-
Design of novel and selective inhibitors of urokinase-type plasminogen activator with improved pharmacokinetic properties for use as antimetastatic agents
-
Schweinitz A., Steinmetzer T., Banke I.J., Arlt M.J., Sturzebecher A., Schuster O., Geissler A., Giersiefen H., Zeslawska E., Jacob U., Kruger A., and Sturzebecher J. Design of novel and selective inhibitors of urokinase-type plasminogen activator with improved pharmacokinetic properties for use as antimetastatic agents. J. Biol. Chem. 279 (2004) 33613-33622
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 33613-33622
-
-
Schweinitz, A.1
Steinmetzer, T.2
Banke, I.J.3
Arlt, M.J.4
Sturzebecher, A.5
Schuster, O.6
Geissler, A.7
Giersiefen, H.8
Zeslawska, E.9
Jacob, U.10
Kruger, A.11
Sturzebecher, J.12
-
36
-
-
0035740252
-
The urokinase-type plasminogen activator system in prostate cancer metastasis
-
Sheng S. The urokinase-type plasminogen activator system in prostate cancer metastasis. Cancer Metastasis Rev. 20 (2001) 287-296
-
(2001)
Cancer Metastasis Rev.
, vol.20
, pp. 287-296
-
-
Sheng, S.1
-
37
-
-
34548272131
-
Activation of PI3K-Akt signaling pathway promotes prostate cancer cell invasion
-
Shukla S., Maclennan G.T., Hartman D.J., Fu P., Resnick M.I., and Gupta S. Activation of PI3K-Akt signaling pathway promotes prostate cancer cell invasion. Int. J. Cancer 121 (2007) 1424-1432
-
(2007)
Int. J. Cancer
, vol.121
, pp. 1424-1432
-
-
Shukla, S.1
Maclennan, G.T.2
Hartman, D.J.3
Fu, P.4
Resnick, M.I.5
Gupta, S.6
-
38
-
-
0036299205
-
Protein kinase C induces motility of breast cancers by upregulating secretion of urokinase-type plasminogen activator through activation of AP-1 and NF-κB
-
Sliva D., English D., Lyons D., and Lloyd Jr. F.P. Protein kinase C induces motility of breast cancers by upregulating secretion of urokinase-type plasminogen activator through activation of AP-1 and NF-κB. Biochem. Biophys. Res. Commun. 290 (2002) 552-557
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.290
, pp. 552-557
-
-
Sliva, D.1
English, D.2
Lyons, D.3
Lloyd Jr., F.P.4
-
39
-
-
0035960116
-
Pamidronate to prevent bone loss during androgen-deprivation therapy for prostate cancer
-
Smith M.R., McGovern F.J., Zietman A.L., Fallon M.A., Hayden D.L., Schoenfeld D.A., Kantoff P.W., and Finkelstein J.S. Pamidronate to prevent bone loss during androgen-deprivation therapy for prostate cancer. N. Engl. J. Med. 345 (2001) 948-955
-
(2001)
N. Engl. J. Med.
, vol.345
, pp. 948-955
-
-
Smith, M.R.1
McGovern, F.J.2
Zietman, A.L.3
Fallon, M.A.4
Hayden, D.L.5
Schoenfeld, D.A.6
Kantoff, P.W.7
Finkelstein, J.S.8
-
40
-
-
0029789967
-
Protein kinase C activates the MEK-ERK pathway in a manner independent of Ras and dependent on Raf
-
Ueda Y., Hirai S., Osada S., Suzuki A., Mizuno K., and Ohno S. Protein kinase C activates the MEK-ERK pathway in a manner independent of Ras and dependent on Raf. J. Biol. Chem. 271 (1996) 23512-23519
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 23512-23519
-
-
Ueda, Y.1
Hirai, S.2
Osada, S.3
Suzuki, A.4
Mizuno, K.5
Ohno, S.6
-
41
-
-
33744795451
-
The effect of bisphosphonates on gene expression: GAPDH as a housekeeping or a new target gene?
-
Valenti M.T., Bertoldo F., Dalle Carbonare L., Azzarello G., Zenari S., Zanatta M., Balducci E., Vinante O., and Lo Cascio V. The effect of bisphosphonates on gene expression: GAPDH as a housekeeping or a new target gene?. BMC Cancer 6 (2006) 49
-
(2006)
BMC Cancer
, vol.6
, pp. 49
-
-
Valenti, M.T.1
Bertoldo, F.2
Dalle Carbonare, L.3
Azzarello, G.4
Zenari, S.5
Zanatta, M.6
Balducci, E.7
Vinante, O.8
Lo Cascio, V.9
-
42
-
-
58249095936
-
PCPH/ENTPD5 expression confers to prostate cancer cells resistance against cisplatin-induced apoptosis through protein kinase Cα-mediated Bcl-2 stabilization
-
Villar J., Quadri H.S., Song I., Tomita Y., Tirado O.M., and Notario V. PCPH/ENTPD5 expression confers to prostate cancer cells resistance against cisplatin-induced apoptosis through protein kinase Cα-mediated Bcl-2 stabilization. Cancer Res. 69 (2009) 102-110
-
(2009)
Cancer Res.
, vol.69
, pp. 102-110
-
-
Villar, J.1
Quadri, H.S.2
Song, I.3
Tomita, Y.4
Tirado, O.M.5
Notario, V.6
-
43
-
-
0036569635
-
Alendronate inhibits invasion of PC-3 prostate cancer cells by affecting the mevalonate pathway
-
Virtanen S.S., Vaananen H.K., Harkonen P.L., and Lakkakorpi P.T. Alendronate inhibits invasion of PC-3 prostate cancer cells by affecting the mevalonate pathway. Cancer Res. 62 (2002) 2708-2714
-
(2002)
Cancer Res.
, vol.62
, pp. 2708-2714
-
-
Virtanen, S.S.1
Vaananen, H.K.2
Harkonen, P.L.3
Lakkakorpi, P.T.4
-
44
-
-
12344264745
-
Targeting Ras and Rho GTPases as opportunities for cancer therapeutics
-
Walker K., and Olson M.F. Targeting Ras and Rho GTPases as opportunities for cancer therapeutics. Curr. Opin. Genet. Dev. 15 (2005) 62-68
-
(2005)
Curr. Opin. Genet. Dev.
, vol.15
, pp. 62-68
-
-
Walker, K.1
Olson, M.F.2
-
45
-
-
0025062503
-
A synthetic peptide substrate for selective assay of protein kinase C
-
Yasuda I., Kishimoto A., Tanaka S., Tominaga M., Sakurai A., and Nishizuka Y. A synthetic peptide substrate for selective assay of protein kinase C. Biochem. Biophys. Res. Commun. 166 (1990) 1220-1227
-
(1990)
Biochem. Biophys. Res. Commun.
, vol.166
, pp. 1220-1227
-
-
Yasuda, I.1
Kishimoto, A.2
Tanaka, S.3
Tominaga, M.4
Sakurai, A.5
Nishizuka, Y.6
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