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Volumn 4, Issue 11, 2009, Pages 1925-1929

4,4-Dimethyl- and diastereomeric 4-hydroxy-4-methyl-(2S)-glutamate analogues display distinct pharmacological profiles at ionotropic glutamate receptors and excitatory amino acid transporters

(8) Bunch, Lennart a Pickering, Darryl S a Gefflaut, Thierry b Vinatier, Virginie b Helaine, Virgil b Amir, Ahmad a Nielsen, Birgitte a Jensen, Anders A a

a UNIVERSITY OF COPENHAGEN (Denmark)

b UNIVERSITÉ CLERMONT AUVERGNE (France)

Author keywords

EAATs; Glutamic acid; Kainic acid; Structure activity relationships; Subtype selective ligands

Indexed keywords

4 HYDROXY 4 METHYLGLUTAMIC ACID; 4 HYDROXYGLUTAMIC ACID; 4,4 DIMETHYLGLUTAMIC ACID; EXCITATORY AMINO ACID TRANSPORTER; GLUTAMIC ACID DERIVATIVE; IONOTROPIC RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; DRUG STRUCTURE; DRUG SYNTHESIS; IC 50; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

AMINO ACID TRANSPORT SYSTEMS; ANIMALS; GLUTAMIC ACID; HUMANS; LIGANDS; MODELS, CHEMICAL; MOLECULAR CONFORMATION; RATS; RECEPTORS, METABOTROPIC GLUTAMATE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 73449083786 PISSN: 18607179 EISSN: 18607187 Source Type: Journal
DOI: 10.1002/cmdc.200900258 Document Type: Article

Times cited : (7)

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