Chronic treatment with the peroxisome proliferator-activated receptor α agonist Wy-14,643 attenuates myocardial respiratory capacity and contractile function

Molecular and Cellular Biochemistry

Volumn 330, Issue 1-2, 2009, Pages 55-62

  Zungu, Makhosazane ^a   Young, Martin E ^b   Stanley, William C ^c   Essop, M Faadiel ^d  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^d STELLENBOSCH UNIVERSITY   (South Africa)

Author keywords

Cardiac contractile function; Mitochondrial respiration; UCP3; Uncoupling; Wy 14,643

Indexed keywords

ADENOSINE DIPHOSPHATE; CYTOCHROME C OXIDASE; CYTOCHROME C OXIDASE 2; PHOSPHOTRANSFERASE; PIRINIXIC ACID; PYRUVATE DEHYDROGENASE; PYRUVATE DEHYDROGENASE KINASE 4; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 3;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE MEASUREMENT; BODY WEIGHT; CONTROLLED STUDY; GENE EXPRESSION; HEART MUSCLE CONTRACTILITY; HEART PERFUSION; HEART WEIGHT; MALE; MITOCHONDRIAL RESPIRATION; NONHUMAN; OXIDATIVE PHOSPHORYLATION; RAT; RESPIRATORY FUNCTION; SYSTOLIC BLOOD PRESSURE; UPREGULATION; WISTAR RAT;

ANIMALS; ANTICHOLESTEREMIC AGENTS; CELL RESPIRATION; MALE; MITOCHONDRIA, HEART; MYOCARDIAL CONTRACTION; PEROXISOME PROLIFERATORS; PPAR ALPHA; PYRIMIDINES; RATS; RATS, WISTAR; UNCOUPLING AGENTS;

RATTUS NORVEGICUS;

EID: 73349120247     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-009-0100-y     Document Type: Article

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