A class I ligase ribozyme with reduced Mg2+ dependence: Selection, sequence analysis, and identification of functional tertiary interactions

RNA

Volumn 15, Issue 12, 2009, Pages 2129-2146

  Bagby, Sarah C ^a,b,c   Bergman, Nicholas H ^a,b,d   Shechner, David M ^a,b   Yen, Catherine ^a,b   Bartel, David P ^a,b  

^a WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d BATTELLE MEMORIAL INSTITUTE   (United States)

Author keywords

Class I ligase; In vitro selection; Interference mapping; NAIM; Ribozyme; RNA structure

Indexed keywords

LIGASE; MAGNESIUM ION; NUCLEIC ACID BASE; RIBOZYME; MAGNESIUM;

AMINO ACID SEQUENCE; ARTICLE; CATALYSIS; CLONE; CONTROLLED STUDY; CRYSTAL STRUCTURE; GENE MUTATION; KINETICS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN INTERACTION; PROTEIN TARGETING; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; DNA SEQUENCE; GENETIC VARIABILITY; GENETICS; METABOLISM; NUCLEOTIDE SEQUENCE; PROTEIN DOMAIN; X RAY CRYSTALLOGRAPHY;

BASE SEQUENCE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; GENETIC VARIATION; KINETICS; LIGASES; MAGNESIUM; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; PROTEIN INTERACTION DOMAINS AND MOTIFS; RNA, CATALYTIC; SEQUENCE ANALYSIS, DNA;

EID: 73349118813     PISSN: 13558382     EISSN: 14699001     Source Type: Journal    
DOI: 10.1261/rna.1912509     Document Type: Article

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