Continuous in vitro evolution of a ribozyme that catalyzes three successive nucleotidyl addition reactions

Chemistry and Biology

Volumn 9, Issue 5, 2002, Pages 585-596

  McGinness, Kathleen E ^a   Wright, Martin C ^a   Joyce, Gerald F ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DARWINIA;

BACTERIOPHAGE T7 RNA POLYMERASE; DNA DIRECTED RNA POLYMERASE; NUCLEOTIDE; PHOSPHORUS; RIBOZYME; RNA LIGASE; VIRUS PROTEIN;

ARTICLE; CATALYSIS; CHEMISTRY; CONFORMATION; ENZYME SPECIFICITY; GENETICS; KINETICS; METABOLISM; MOLECULAR EVOLUTION; MOLECULAR GENETICS; MUTAGENESIS; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PROMOTER REGION; SEQUENCE ANALYSIS;

BASE SEQUENCE; CATALYSIS; DNA-DIRECTED RNA POLYMERASES; EVOLUTION, MOLECULAR; KINETICS; MOLECULAR SEQUENCE DATA; MUTAGENESIS; NUCLEIC ACID CONFORMATION; NUCLEOTIDES; PHOSPHORUS RADIOISOTOPES; POLYMERASE CHAIN REACTION; PROMOTER REGIONS (GENETICS); RNA LIGASE (ATP); RNA, CATALYTIC; SEQUENCE ANALYSIS, RNA; SUBSTRATE SPECIFICITY; VIRAL PROTEINS;

EID: 0036015841     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-5521(02)00136-9     Document Type: Article

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