Identification of human UDP-glucuronosyltransferase isoforms responsible for the glucuronidation of glycyrrhetinic acid

Drug Metabolism and Pharmacokinetics

Volumn 24, Issue 6, 2009, Pages 523-528

  Lu, Yang ^a   Zhu, Jing ^a   Chen, Xijing ^a   Li, Ning ^a   Fu, Feifei ^a   He, Jiake ^a   Wang, Guangji ^a   Zhang, Lingli ^a   Zheng, Yi ^a   Qiu, Zhixia ^a   Yu, Xue ^a   Han, Deen ^a   Wu, Lei ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Enzyme kinetics; Glucuronidation; Glycyrrhetinic acid; Liver microsomes; Recombinant human UGT; UDP glucuronosyltransferase

Indexed keywords

FLURBIPROFEN; GLUCURONOSYLTRANSFERASE; GLUCURONOSYLTRANSFERASE 1A1; GLUCURONOSYLTRANSFERASE 1A3; GLUCURONOSYLTRANSFERASE 2B4; GLUCURONOSYLTRANSFERASE 2B7; GLYCYRRHETINIC ACID; IMIPRAMINE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME KINETICS; ENZYME SUBSTRATE; GLUCURONIDATION; HUMAN; HUMAN CELL; IC 50; LIVER MICROSOME; METABOLITE; PROTEIN ANALYSIS;

EID: 73349118166     PISSN: 13474367     EISSN: 18800920     Source Type: Journal    
DOI: 10.2133/dmpk.24.523     Document Type: Article

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