Glucuronide-sulfate diconjugate as a novel metabolite of glycyrrhetic acid in rat bile

Drug Metabolism and Pharmacokinetics

Volumn 23, Issue 3, 2008, Pages 175-180

  Jing, Jing ^a   Ren, Weichao ^a   Chen, Xijing ^a   Wang, Yue ^a   Yu, Qiaoling ^a   Wang, Guangji ^a   Davey, Andrew K ^b   Wang, Jiping ^b   Jing, Ning ^c  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b UNIVERSITY OF SOUTH AUSTRALIA   (Australia)

^c AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

Author keywords

Bile; Diconjugate; Glycyrrhetic acid; LC MS; Metabolites

Indexed keywords

ALKALINE EARTH METAL; BETA GLUCURONIDASE; DRUG METABOLITE; GLUCURONIDE; GLYCYRRHETINIC ACID; ION; SULFATE; ANTIINFLAMMATORY AGENT;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ARTICLE; BILE; DRUG STRUCTURE; DRUG TRANSFORMATION; GLUCURONIDATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; NONHUMAN; RAT; SINGLE DRUG DOSE; SULFONATION; ANIMAL; BIOTRANSFORMATION; CHEMICAL STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; INTRAVENOUS DRUG ADMINISTRATION; METABOLISM; SPRAGUE DAWLEY RAT;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BILE; BIOTRANSFORMATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GLUCURONIDES; GLYCYRRHETINIC ACID; INJECTIONS, INTRAVENOUS; MALE; MOLECULAR STRUCTURE; RATS; RATS, SPRAGUE-DAWLEY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SULFATES;

EID: 48849092904     PISSN: 13474367     EISSN: 18800920     Source Type: Journal    
DOI: 10.2133/dmpk.23.175     Document Type: Article

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