ERK1/2 activation induced by inflammatory cytokines compromises effective host tissue integration of engineered cartilage

Tissue Engineering - Part A

Volumn 15, Issue 10, 2009, Pages 2825-2835

  Djouad, Farida ^a,b   Rackwitz, Lars ^a,c   Song, Yingjie ^a   Janjanin, Sasa ^a,d   Tuan, Rocky S ^a  

^a NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

^b HÔPITAL SAINT ELOI   (France)

^c UNIVERSITY OF WÜRZBURG   (Germany)

^d KBC Zagreb   (Croatia)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMECHANICS; CARTILAGE; LIGAMENTS; RESTORATION; SIGNALING;

AGAROSE; ARTICULAR CARTILAGES; CARTILAGE DEFECTS; CATASTROPHIC EFFECTS; CHEMICAL ENTITY; CHONDROCYTES; CYTOKINES; DELETERIOUS EFFECTS; ENGINEERED CARTILAGE; EXTRACELLULAR MATRICES; EXTRACELLULAR-REGULATED KINASE; FUNCTIONAL INTEGRATION; HOST TISSUES; IN-VITRO; INFLAMMATORY CYTOKINES; INTEGRATIVE PROPERTIES; INTERFACE REGIONS; INTERFACE STRENGTH; INTERLEUKIN-1; JOINT SURFACES; LONG-TERM VIABILITY; MECHANICAL INTEGRITY; MECHANICALLY STABLE; PROINFLAMMATORY CYTOKINES; PUSH-OUT TESTS; REPAIR TISSUES; SIGNALING CASCADES; SIGNALING PATHWAYS; TIME-DEPENDENT; TISSUE ENGINEERED CARTILAGE; TUMOR NECROSIS FACTORS; YOUNG'S MODULUS;

JOINTS (ANATOMY);

1,3 BUTADIENE DERIVATIVE; 1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; GELATINASE A; GELATINASE B; INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NITRILE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL; ARTICLE; BIOMECHANICS; CARTILAGE; CATTLE; CYTOLOGY; DRUG EFFECT; IMMUNOHISTOCHEMISTRY; METABOLISM; METHODOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TISSUE ENGINEERING; WESTERN BLOTTING;

ANIMALS; BIOMECHANICS; BLOTTING, WESTERN; BUTADIENES; CARTILAGE; CATTLE; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-1BETA; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NITRILES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TISSUE ENGINEERING; TUMOR NECROSIS FACTOR-ALPHA;

EID: 73349118138     PISSN: 19373341     EISSN: 1937335X     Source Type: Journal    
DOI: 10.1089/ten.tea.2008.0663     Document Type: Article

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