Chronic bacterial osteomyelitis suppression of tumor growth requires innate immune responses

Cancer Immunology, Immunotherapy

Volumn 59, Issue 3, 2010, Pages 367-378

  Sottnik, Joseph L ^a   U'Ren, Lance W ^a   Thamm, Douglas H ^a   Withrow, Stephen J ^a   Dow, Steven W ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

Inflammation; Innate immunity; Osteosarcoma

Indexed keywords

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; BACTERIAL INFECTION; BACTERIAL STRAIN; CANCER INHIBITION; CARCINOGENESIS; CELLULAR IMMUNITY; CHRONIC OSTEOMYELITIS; CONTROLLED STUDY; CYTOLYSIS; ENDOTHELIUM CELL; FEMALE; INFLAMMATION; INNATE IMMUNITY; MONOCYTE; MOUSE; MOUSE STRAIN; NATURAL KILLER CELL; NONHUMAN; OSTEOSARCOMA; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS; TUMOR ASSOCIATED LEUKOCYTE; TUMOR IMMUNITY; TUMOR VASCULARIZATION;

ANIMALS; CHRONIC DISEASE; DISEASE MODELS, ANIMAL; IMMUNITY, INNATE; KILLER CELLS, NATURAL; MACROPHAGES; MICE; MICE, INBRED C3H; MICE, INBRED STRAINS; MONOCYTES; NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC; OSTEOMYELITIS; OSTEOSARCOMA; STAPHYLOCOCCAL INFECTIONS;

EID: 73349104928     PISSN: 03407004     EISSN: 14320851     Source Type: Journal    
DOI: 10.1007/s00262-009-0755-y     Document Type: Article

References (56)

1. WB Coley 1893 A preliminary note on the treatment of inoperable sarcoma by the toxic product of erysipelas Postgrad Med 8 278 286
2. CG Burdick 1937 William Bradley Coley, 1862-1936 Ann Surg 105 152 155 1:STN:280:DC%2BD2srktF2ksQ%3D%3D 17856903
3. EB Rankin D Yu J Jiang H Shen EJ Pearce MH Goldschmidt DE Levy TV Golovkina CA Hunter A Thomas-Tikhonenko 2003 An essential role of Th1 responses and interferon gamma in infection-mediated suppression of neoplastic growth Cancer Biol Ther 2 687 693 1:CAS:528:DC%2BD2cXhvVCjsb0%3D 14688478
4. A Thomas-Tikhonenko CA Hunter 2003 Infection and cancer: the common vein Cytokine Growth Factor Rev 14 67 77 10.1016/S1359-6101(02)00071-0 1:CAS:528:DC%2BD38XpsFarsbo%3D 12485620 (Pubitemid 36098432)
5. K Hayashi M Zhao K Yamauchi N Yamamoto H Tsuchiya K Tomita H Kishimoto M Bouvet RM Hoffman 2009 Systemic targeting of primary bone tumor and lung metastasis of high-grade osteosarcoma in nude mice with a tumor-selective strain of Salmonella typhimurium Cell Cycle 8 870 875 1:CAS:528:DC%2BD1MXlvFWisL4%3D 19221501
6. CH Lee CL Wu AL Shiau 2008 Salmonella choleraesuis as an anticancer agent in a syngeneic model of orthotopic hepatocellular carcinoma Int J Cancer 122 930 935 10.1002/ijc.23047 1:CAS:528:DC%2BD1cXhsFShsb4%3D 17960612
7. RM Ryan J Green CE Lewis 2006 Use of bacteria in anti-cancer therapies Bioessays 28 84 94 10.1002/bies.20336 1:CAS:528:DC%2BD28XptlWhsg%3D%3D 16369949
8. DH Thamm ID Kurzman I King Z Li M Sznol RR Dubielzig DM Vail EG MacEwen 2005 Systemic administration of an attenuated, tumor-targeting Salmonella typhimurium to dogs with spontaneous neoplasia: phase I evaluation Clin Cancer Res 11 4827 4834 10.1158/1078-0432.CCR-04-2510 1:CAS:528:DC%2BD2MXlvVGgsrk%3D 16000580 (Pubitemid 41557202)
9. DH Kirn SH Thorne 2009 Targeted and armed oncolytic poxviruses: a novel multi-mechanistic therapeutic class for cancer Nat Rev Cancer 9 64 71 10.1038/nrc2545 1:CAS:528:DC%2BD1MXpt1eh 19104515
10. M Loeffler G Le'Negrate M Krajewska JC Reed 2009 Salmonella typhimurium engineered to produce CCL21 inhibit tumor growth Cancer Immunol Immunother 58 769 775 10.1007/s00262-008-0555-9 1:CAS:528:DC%2BD1MXit1Citbg%3D 18633610
11. RM Ryan J Green PJ Williams S Tazzyman S Hunt JH Harmey SC Kehoe CE Lewis 2009 Bacterial delivery of a novel cytolysin to hypoxic areas of solid tumors Gene Ther 16 329 339 10.1038/gt.2008.188 1:CAS:528:DC%2BD1MXhtFCisr0%3D 19177133
12. BS Sorenson KL Banton NL Frykman AS Leonard DA Saltzman 2008 Attenuated Salmonella typhimurium with IL-2 gene reduces pulmonary metastases in murine osteosarcoma Clin Orthop Relat Res 466 1285 1291 10.1007/s11999-008-0243-2 18421536
13. J Wei J Wahl T Nakamura D Stiller T Mertens KM Debatin C Beltinger 2007 Targeted release of oncolytic measles virus by blood outgrowth endothelial cells in situ inhibits orthotopic gliomas Gene Ther 14 1573 1586 10.1038/sj.gt. 3303027 1:CAS:528:DC%2BD2sXht1Kjs77N 17898797 (Pubitemid 350056229)
14. F Mueller B Fuchs B Kaser-Hotz 2007 Comparative biology of human and canine osteosarcoma Anticancer Res 27 155 164 1:CAS:528:DC%2BD2sXjs1Wns70%3D 17352227
15. M Paoloni C Khanna 2008 Translation of new cancer treatments from pet dogs to humans Nat Rev Cancer 8 147 156 10.1038/nrc2273 1:CAS:528: DC%2BD1cXhtVGhsLw%3D 18202698 (Pubitemid 351161319)
16. C Khanna 2008 Novel targets with potential therapeutic applications in osteosarcoma Curr Oncol Rep 10 350 358 10.1007/s11912-008-0054-3 1:CAS:528:DC%2BD1cXhtFems7bM 18778562
17. SS Bielack D Carrle J Hardes A Schuck M Paulussen 2008 Bone tumors in adolescents and young adults Curr Treat Options Oncol 9 67 80 10.1007/s11864-008-0057-1 18449804
18. BD Lascelles WS Dernell MT Correa M Lafferty CM Devitt CA Kuntz RC Straw SJ Withrow 2005 Improved survival associated with postoperative wound infection in dogs treated with limb-salvage surgery for osteosarcoma Ann Surg Oncol 12 1073 1083 10.1245/ASO.2005.01.011 16252138 (Pubitemid 41660684)
19. LM Jeys RJ Grimer SR Carter RM Tillman A Abudu 2007 Post operative infection and increased survival in osteosarcoma patients: are they associated? Ann Surg Oncol 14 2887 2895 1:STN:280:DC%2BD2srmtVyntw%3D%3D 17653803
20. JA Lee MS Kim DH Kim JS Lim KD Park WH Cho WS Song SY Lee DG Jeon 2008 Postoperative infection and survival in osteosarcoma patients Ann Surg Oncol 16 147 151 10.1245/s10434-008-0184-8 18979137
21. T Asai T Ueda K Itoh K Yoshioka Y Aoki S Mori H Yoshikawa 1998 Establishment and characterization of a murine osteosarcoma cell line (LM8) with high metastatic potential to the lung Int J Cancer 76 418 422 10.1002/(SICI)1097-0215(19980504)76:3<418::AID-IJC21>3.0.CO;2-5 1:CAS:528:DyaK1cXjtVOqs7c%3D 9579581 (Pubitemid 28282943)
22. T Yoshii S Magara D Miyai E Kuroki H Nishimura S Furudoi T Komori 2002 Inhibitory effect of roxithromycin on the local levels of bone-resorbing cytokines in an experimental model of murine osteomyelitis J Antimicrob Chemother 50 289 292 10.1093/jac/dkf124 1:CAS:528:DC%2BD38Xms1Klsro%3D 12161415
23. SW Dow LG Fradkin DH Liggitt AP Willson TD Heath TA Potter 1999 Lipid-DNA complexes induce potent activation of innate immune responses and antitumor activity when administered intravenously J Immunol 163 1552 1561 1:CAS:528:DyaK1MXkslOgsLk%3D 10415059
24. S Gazzaniga AI Bravo A Guglielmotti N van Rooijen F Maschi A Vecchi A Mantovani J Mordoh R Wainstok 2007 Targeting tumor-associated macrophages and inhibition of MCP-1 reduce angiogenesis and tumor growth in a human melanoma xenograft J Invest Dermatol 127 2031 2041 10.1038/sj.jid.5700827 1:CAS:528:DC%2BD2sXns1yls78%3D 17460736 (Pubitemid 47075380)
25. I Huitinga JG Damoiseaux N van Rooijen EA Dopp CD Dijkstra 1992 Liposome mediated affection of monocytes Immunobiology 185 11 19 1:CAS:528: DyaK38XmsV2rt70%3D 1398738
26. N Van Rooijen A Sanders 1994 Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications J Immunol Methods 174 83 93 10.1016/0022-1759(94)90012-4 8083541 (Pubitemid 124013923)
27. N van Rooijen R van Nieuwmegen 1984 Elimination of phagocytic cells in the spleen after intravenous injection of liposome-encapsulated dichloromethylene diphosphonate. An enzyme-histochemical study Cell Tissue Res 238 355 358 10.1007/BF00217308 6239690
28. M Mathes M Jordan S Dow 2006 Evaluation of liposomal clodronate in experimental spontaneous autoimmune hemolytic anemia in dogs Exp Hematol 34 1393 1402 10.1016/j.exphem.2006.05.014 1:CAS:528:DC%2BD28Xps1Omu7c%3D 16982332 (Pubitemid 44374833)
29. CA Hunter D Yu M Gee CV Ngo C Sevignani M Goldschmidt TV Golovkina S Evans WF Lee A Thomas-Tikhonenko 2001 Cutting edge: systemic inhibition of angiogenesis underlies resistance to tumors during acute toxoplasmosis J Immunol 166 5878 5881 1:CAS:528:DC%2BD3MXjsFCqsro%3D 11342601
30. F Bertolini Y Shaked P Mancuso RS Kerbel 2006 The multifaceted circulating endothelial cell in cancer: towards marker and target identification Nat Rev Cancer 6 835 845 10.1038/nrc1971 1:CAS:528:DC%2BD28XhtFWhs7bL 17036040 (Pubitemid 44629895)
31. C Murdoch M Muthana SB Coffelt CE Lewis 2008 The role of myeloid cells in the promotion of tumour angiogenesis Nat Rev Cancer 8 618 631 10.1038/nrc2444 1:CAS:528:DC%2BD1cXovV2lsrY%3D 18633355
32. JO Kim SS Jung SY Kim TY Kim DW Shin JH Lee YH Lee 2007 Inhibition of Lewis lung carcinoma growth by Toxoplasma gondii through induction of Th1 immune responses and inhibition of angiogenesis J Korean Med Sci 22 Suppl S38 S46 10.3346/jkms.2007.22.S.S38 1:CAS:528:DC%2BD2sXhsVektrbJ 17923753
33. MN Saleh SJ Goldman AF LoBuglio AC Beall H Sabio MC McCord L Minasian RK Alpaugh LM Weiner DH Munn 1995 CD16+ monocytes in patients with cancer: spontaneous elevation and pharmacologic induction by recombinant human macrophage colony-stimulating factor Blood 85 2910 2917 1:CAS:528: DyaK2MXls1Sqs7k%3D 7742551
34. F Tacke GJ Randolph 2006 Migratory fate and differentiation of blood monocyte subsets Immunobiology 211 609 618 10.1016/j.imbio.2006.05.025 1:CAS:528:DC%2BD28XhtVGlsrvK 16920499 (Pubitemid 44241645)
35. F Geissmann S Jung DR Littman 2003 Blood monocytes consist of two principal subsets with distinct migratory properties Immunity 19 71 82 10.1016/S1074-7613(03)00174-2 1:CAS:528:DC%2BD3sXlvVOrsrk%3D 12871640 (Pubitemid 36859902)
36. D Strauss-Ayali SM Conrad DM Mosser 2007 Monocyte subpopulations and their differentiation patterns during infection J Leukoc Biol 82 244 252 10.1189/jlb.0307191 1:CAS:528:DC%2BD2sXos12rtbg%3D 17475785 (Pubitemid 47230633)
37. C Sunderkotter T Nikolic MJ Dillon N Van Rooijen M Stehling DA Drevets PJ Leenen 2004 Subpopulations of mouse blood monocytes differ in maturation stage and inflammatory response J Immunol 172 4410 4417 15034056
38. L Arnold A Henry F Poron Y Baba-Amer N van Rooijen A Plonquet RK Gherardi B Chazaud 2007 Inflammatory monocytes recruited after skeletal muscle injury switch into antiinflammatory macrophages to support myogenesis J Exp Med 204 1057 1069 10.1084/jem.20070075 1:CAS:528:DC%2BD2sXlsFSjtrw%3D 17485518 (Pubitemid 46798150)
39. C Varol S Yona S Jung 2009 Origins and tissue-context-dependent fates of blood monocytes Immunol Cell Biol 87 30 38 10.1038/icb.2008.90 19048016
40. CE Lewis JW Pollard 2006 Distinct role of macrophages in different tumor microenvironments Cancer Res 66 605 612 10.1158/0008-5472.CAN-05-4005 1:CAS:528:DC%2BD28XlsFOmtw%3D%3D 16423985 (Pubitemid 43165918)
41. DM Mosser JP Edwards 2008 Exploring the full spectrum of macrophage activation Nat Rev Immunol 8 958 969 10.1038/nri2448 1:CAS:528: DC%2BD1cXhsVWlsLfI 19029990
42. A Sica P Allavena A Mantovani 2008 Cancer related inflammation: the macrophage connection Cancer Lett 267 204 215 10.1016/j.canlet.2008.03.028 1:CAS:528:DC%2BD1cXovF2hsLk%3D 18448242
43. F Tacke F Ginhoux C Jakubzick N van Rooijen M Merad GJ Randolph 2006 Immature monocytes acquire antigens from other cells in the bone marrow and present them to T cells after maturing in the periphery J Exp Med 203 583 597 10.1084/jem.20052119 1:CAS:528:DC%2BD28XjsVSqtbo%3D 16492803
44. K Hiraoka M Zenmyo K Watari H Iguchi A Fotovati YN Kimura F Hosoi T Shoda K Nagata H Osada M Ono M Kuwano 2008 Inhibition of bone and muscle metastases of lung cancer cells by a decrease in the number of monocytes/macrophages Cancer Sci 99 1595 1602 10.1111/j.1349-7006.2008.00880.x 1:CAS:528:DC%2BD1cXhtFKnur7I 18754872
45. NR Miselis ZJ Wu N Van Rooijen AB Kane 2008 Targeting tumor-associated macrophages in an orthotopic murine model of diffuse malignant mesothelioma Mol Cancer Ther 7 788 799 10.1158/1535-7163.MCT-07-0579 1:CAS:528: DC%2BD1cXks1Gms7g%3D 18375821 (Pubitemid 351551032)
46. SM Zeisberger B Odermatt C Marty AH Zehnder-Fjallman K Ballmer-Hofer RA Schwendener 2006 Clodronate-liposome-mediated depletion of tumour-associated macrophages: a new and highly effective antiangiogenic therapy approach Br J Cancer 95 272 281 10.1038/sj.bjc.6603240 1:CAS:528:DC%2BD28Xnsl2iu7o%3D 16832418 (Pubitemid 44187587)
47. F Eriksson P Tsagozis K Lundberg R Parsa SM Mangsbo MA Persson RA Harris P Pisa 2009 Tumor-specific bacteriophages induce tumor destruction through activation of tumor-associated macrophages J Immunol 182 3105 3111 10.4049/jimmunol.0800224 1:CAS:528:DC%2BD1MXitFKgsr0%3D 19234207
48. S Homma Y Sagawa H Komita S Koido E Nagasaki Y Ryoma M Okamoto 2007 Mechanism of antitumor effect on mouse hepatocellular carcinoma by intratumoral injection of OK-432, a streptococcal preparation Cancer Immunol Immunother 56 1265 1274 10.1007/s00262-006-0277-9 17219148 (Pubitemid 46763939)
49. R Friesel A Komoriya T Maciag 1987 Inhibition of endothelial cell proliferation by gamma-interferon J Cell Biol 104 689 696 10.1083/jcb.104.3.689 1:CAS:528:DyaL2sXhtlKksLs%3D 3102503 (Pubitemid 17024724)
50. K Norioka EC Borden R Auerbach 1991 Inhibitory effects of cytokines on vascular endothelial cells: synergistic interactions among interferon-gamma, tumor necrosis factor-alpha, and interleukin-1 J Immunother 12 13 18
51. A Mantovani S Sozzani M Locati P Allavena A Sica 2002 Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes Trends Immunol 23 549 555 10.1016/S1471-4906(02)02302-5 1:CAS:528:DC%2BD38XotVKktrc%3D 12401408 (Pubitemid 35223554)
52. HF Dvorak 1986 Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing N Engl J Med 315 1650 1659 1:STN:280:DyaL2s%2FmsV2mtw%3D%3D 3537791
53. T Katakura M Miyazaki M Kobayashi DN Herndon F Suzuki 2004 CCL17 and IL-10 as effectors that enable alternatively activated macrophages to inhibit the generation of classically activated macrophages J Immunol 172 1407 1413 1:CAS:528:DC%2BD2cXptlyktw%3D%3D 14734716
54. EM Bluman KJ Bartynski BR Avalos MA Caligiuri 1996 Human natural killer cells produce abundant macrophage inflammatory protein-1 alpha in response to monocyte-derived cytokines J Clin Invest 97 2722 2727 10.1172/JCI118726 1:CAS:528:DyaK28XjvVWksrg%3D 8675682
55. WE Carson ME Ross RA Baiocchi MJ Marien N Boiani K Grabstein MA Caligiuri 1995 Endogenous production of interleukin 15 by activated human monocytes is critical for optimal production of interferon-gamma by natural killer cells in vitro J Clin Invest 96 2578 2582 10.1172/JCI118321 1:CAS:528: DyaK28XmtVejsQ%3D%3D 8675621
56. S Hegde X Chen JM Keaton F Reddington GS Besra JE Gumperz 2007 NKT cells direct monocytes into a DC differentiation pathway J Leukoc Biol 81 1224 1235 10.1189/jlb.1206718 1:CAS:528:DC%2BD2sXlsVWnurg%3D 17311932 (Pubitemid 46702041)