Mitochondrial genomic instability in colorectal cancer: No correlation to nuclear microsatellite instability and allelic deletion of hMSH2, hMLH1, and p53 Genes, but prediction of better survival for dukes' stage C disease

Annals of Surgical Oncology

Volumn 16, Issue 10, 2009, Pages 2918-2925

  Tsai, Ming Hong ^a,b   Fang, Woei Horng ^c,d   Lin, Shu Wha ^c,d   Yen, Sou Jhy ^a,b   Chou, Shao Jiun ^a,b   Yang, Ya Chien ^c,d  

^a FU JEN CATHOLIC UNIVERSITY   (Taiwan)

^b CARDINAL TIEN HOSPITAL   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^d NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN MLH1; PROTEIN MSH2; PROTEIN P53; MITOCHONDRIAL DNA; MLH1 PROTEIN, HUMAN; MSH2 PROTEIN, HUMAN; NUCLEAR PROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TP53 PROTEIN, HUMAN; TUMOR MARKER;

ADULT; AGED; ALLELE; ARTICLE; CANCER SURVIVAL; COLORECTAL CARCINOMA; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE FREE SURVIVAL; DISEASE SEVERITY; FEMALE; GENE DELETION; GENE FREQUENCY; GENOMIC INSTABILITY; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MICROSATELLITE INSTABILITY; MITOCHONDRIAL GENOME; OVERALL SURVIVAL; PROGNOSIS; CANCER STAGING; CELL NUCLEUS; COLORECTAL TUMOR; FOLLOW UP; GENETICS; MIDDLE AGED; MITOCHONDRION; PATHOLOGY; SURVIVAL RATE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADULT; AGED; AGED, 80 AND OVER; CELL NUCLEUS; COLORECTAL NEOPLASMS; DNA, MITOCHONDRIAL; FEMALE; FOLLOW-UP STUDIES; HUMANS; LOSS OF HETEROZYGOSITY; MALE; MICROSATELLITE INSTABILITY; MIDDLE AGED; MITOCHONDRIA; MUTS HOMOLOG 2 PROTEIN; NEOPLASM STAGING; NUCLEAR PROTEINS; PROGNOSIS; SEQUENCE DELETION; SURVIVAL RATE; TUMOR MARKERS, BIOLOGICAL; TUMOR SUPPRESSOR PROTEIN P53;

EID: 73349102534     PISSN: 10689265     EISSN: 15344681     Source Type: Journal    
DOI: 10.1245/s10434-009-0581-7     Document Type: Article

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