Hwp1 and related adhesins contribute to both mating and biofilm formation in Candida albicans

Eukaryotic Cell

Volumn 8, Issue 12, 2009, Pages 1909-1913

  Ene, Iuliana V ^a,b   Bennett, Richard J ^a  

^a BROWN UNIVERSITY   (United States)

^b UNIVERSITY OF ABERDEEN   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

FUNGAL PROTEIN; HWP1 PROTEIN, CANDIDA ALBICANS; MEMBRANE PROTEIN;

ARTICLE; BIOFILM; CANDIDA ALBICANS; CELL MEMBRANE; CYTOLOGY; FUNGAL GENE; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; PHYSIOLOGY;

BIOFILMS; CANDIDA ALBICANS; CELL MEMBRANE; FUNGAL PROTEINS; GENES, MATING TYPE, FUNGAL; MEMBRANE GLYCOPROTEINS;

CANDIDA ALBICANS;

EID: 73349094344     PISSN: 15359778     EISSN: None     Source Type: Journal    
DOI: 10.1128/EC.00245-09     Document Type: Article

References (36)

1. Bennett, R. J., and A. D. Johnson. 2003. Completion of a parasexual cycle in Candida albicans by induced chromosome loss in tetraploid strains. EMBO J. 22:2505-2515.
2. Bennett, R. J., and A. D. Johnson. 2005. Mating in Candida albicans and the search for a sexual cycle. Annu. Rev. Microbiol. 59:233-255.
3. Bennett, R. J., and A. D. Johnson. 2006. The role of nutrient regulation and the Gpa2 protein in the mating pheromone response of C. albicans. Mol. Microbiol. 62:100-119.
4. Bennett, R. J., M. A. Uhl, M. G. Miller, and A. D. Johnson. 2003. Identification and characterization of a Candida albicans mating pheromone. Mol. Cell. Biol. 23:8189-8201.
5. Braun, B. R., W. S. Head, M. X. Wang, and A. D. Johnson. 2000. Identification and characterization of TUPI-regulated genes In Candida albicans. Genetics 156:31-44.
6. Butler, G., M. D. Rasmussen, M. F. Lin, M. A. Santos, S. Sakthikumar, C. A. Munro, E. Rheinbay, M. Grabherr, A. Forche, J. L. Reedy, I. Agrafioti, M. B. Arnaud, S. Bates, A. J. Brown, S. Brunke, M. C. Costanzo, D. A. Fitzpatrick, P. W. de Groot, D. Harris, L. L. Hoyer, B. Hube, F. M. Klis, C. Kodira, N. Lennard, M. E. Logue, R. Martin, A. M. Neiman, E. Nikolaou, M. A. Quail, J. Quinn, M. C. Santos, F. F. Schmitzberger, G. Sherlock, P. Shah, K A. Silverstein, M. S. Skrzypek, D. Soll, R. Staggs, I. Stansfield, M. P. Stumpf, P. E. Sudbery, T. Srikantha, Q. Zeng, J. Berman, M. Berriman, J. Heitman, N. A. Gow, M. C. Lorenz, B. W. Birren, M. Kellis, and C. A. Cuomo. 2009. Evolution of pathogenicity and sexual reproduction in eight Candida genomes. Nature 459:657-662.
7. Calderone, R. A., and W. A. Fonzi. 2001. Virulence factors of Candida albicans. Trends Microbiol. 9:327-335.
8. Daniels, K. J., S. R. Lockhart, J. F. Staab, P. Sundstrom, and D. R. Soll. 2003. The adhesin Hwp1. and the first daughter cell localize to the a/a portion of the conjugation bridge during Candida albicans mating. Mol. Biol. Cell 14:4920-4930.
9. Daniels, K. J., T. Srikantha, S. R. Lockhart, C. Pujol, and D. R. Soil. 2006. Opaque cells signal white cells to form biofllms in Candida albicans. EMBO J. 25:2240-2252.
10. Fonzi, W. A., and M. Y. Irwin. 1.993. Isogenic strain construction and gene mapping in Candida albicans. Genetics 134:717-728.
11. Hull, C. M., R. M. Raisner, and A. D. Johnson. 2000. Evidence for mating of the "asexual" yeast Candida albicans in a mammalian host. Science 289:307-310.
12. Janbon, G., F. Sherman, and E. Rustchenko. 1998. Monosomy of a specific chromosome determines L-sorbose utilization: a novel regulatory mechanism in Candida albicans. Proc. Nat1. Acad. Sci. USA 95:5150-5155.
13. Kadosh, D., and A. D. Johnson. 2001. Rfg1, a protein related to the Saccharomyces cerevisiae hypoxic regulator Roxi, controls filamentous growth and virulence in Candida albicans. Mol. Cell. Biol. 21:2496-2505.
14. Kadosh, D., and A. D. Johnson. 2005. Induction of the Candida albicans filamentous growth program, by relief of transcriptional, repression: a genome-wide analysis. Mol. Biol. Cell 16:2903-2912.
15. Lachke, S. A., S. R. Lockhart, K. J. Daniels, and D. R. Soll. 2003. Skin facilitates Candida albicans mating. Infect. Immun. 71:4970-4976.
16. Lipke, P. N., and J. Kurjan. 1992. Sexual, agglutination in budding yeasts: structure, function, and regulation of adhesion glycoproteins. Microbiol. Rev. 56:180-194.
17. Lipke, P. N., D. Wojciechowicz, and J. Kurjan. 1989. AGα1 is the structural gene for the Saccharomyces cerevisiae α-agglutinin, a cell surface glycoprotein involved in cell-cell interactions during mating. Mol. Cell. Biol. 9:3155-3165.
18. Liu, H. 2002. Co-regulation of pathogenesis with dimorphism and phenotypic switching in Candida albicans, a commensal, and a pathogen. Int. J. Med. Microbiol. 292:299-311.
19. Lockhart, S. R., C. Pujol, K. J. Daniels, M. G. Miller, A. D. Johnson, M. A. Pfaller, and D. R. Soll. 2002. In Candida albicans, white-opaque switchers are homozygous for mating type. Genetics 162:737-745.
20. Magee, B. B., and P. T. Magee. 2000. Induction of mating in Candida albicans by construction of MTLa and MTLα strains. Science 289:310-313.
21. Miller, M. G., and A. D. Johnson. 2002. White-opaque switching in Candida albicans is controlled by mating-type locus homeodomain proteins and allows efficient mating. Cell 110:293-302.
22. Nobile, C. J., D. R. Andes, J. E. Nett, F. J. Smith, F. Yue, Q. T. Phan, J. E. Edwards, S. G. Filler, and A. P. Mitchell. 2006. Critical role of Bcr1-dependent adhesins in C. albicans biofilm formation in vitro and in vivo. PLoS Pathog. 2:e63.
23. Nobile, C. J., and A. P. Mitchell. 2006. Genetics and genomics of Candida albicans biofllm formation. Cell. Microbiol. 8:1382-1391.
24. Nobile, C. J., J. E. Nett, D. R. Andes, and A. P. Mitchell. 2006. Function of Candida albicans adhesin Hwpl in biofilm formation. Eukaryot. Cell 5:1604-1610.
25. Nobile, C. J., H. A. Schneider, J. E. Nett, D. C. Sheppard, S. G. Filler, D. R. Andes, and A. P. Mitchell. 2008. Complementary adhesin function in C. albicans biofllm formation. Curr. Biol. 18:1017-1024.
26. Noble, S. M., and A. D. Johnson. 2005. Strains and strategies for large-scale gene deletion studies of the diploid human fungal pathogen. Candida albicans. Eukaryot. Cell 4:298-309.
27. Pfaller, M. A., and D. J. Diekema. 2007. Epidemiology of invasive candidiasis: a persistent public health problem. Clin. Microbiol. Rev. 20:133-163.
28. Reuss, O., A. Vik, R. Kolter, and J. Morschhauser. 2004. The SAT1 flipper, an optimized tool for gene disruption in Candida albicans. Gene 341:119-127.
29. Roy, A., C. F. Lu, D. L. Marykwas, P. N. Lipke, and J. Kurjan. 1991. The AGA1 product is involved in cell surface attachment of the Saccharomyces cerevisiae cell, adhesion glycoprotein α-agglutinin. Mol. Cell. Biol. 11:4196-4206.
30. Schaefer, D., P. Cote, M. Whiteway, and R. J. Bennett. 2007. Barrier activity in Candida albicans mediates pheromone degradation and promotes mating. Eukaryot. Cell 6:907-918.
31. Soll, D. R. 2004. Mating-type locus homozygosis, phenotypic switching and mating: a unique sequence of dependencies in Candida albicans. Bioessays 26:10-20.
32. Staab, J. F., S. D. Bradway, P. L. Fidel, and P. Sundstrom. 1999. Adhesive and mammalian transglutaminase substrate properties of Candida albicans Hwp1. Science 283:1535-1538.
33. Sundstrom, P. 2002. Adhesion in Candida spp. Cell. Microbiol. 4:461-469.
34. Tsong, A. E., B. B. Tuch, H. Li, and A. D. Johnson. 2006. Evolution of alternative transcriptional circuits with identical logic. Nature 443:415-420.
35. Whiteway, M., and U. Oberholzer. 2004. Candida morphogenesis and hostpathogen interactions. Curr. Opin. Microbiol. 7:350-357.
36. 1 dependency. Eukaryot. Cell 4:1175-1190.