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73249144558
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The preoptimized geometries by HF/3-21G* were taken to be the input geometries for final optimization by B3LYP/6-31G*. Single point energies and all electronic properties were calculated by B3LYP/6-31G*.
-
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24
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73249144764
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note
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Preliminary experiments suggested that in the glycosidation of α-disaccharide donors at the 1β-position of the ribose moiety with indoline as an acceptor, a bulky protecting group, such as TBS group, at the 5-primary hydroxyl of the donor might prevent the glycosidation to proceed.
-
-
-
-
26
-
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73249142809
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note
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The anomeric β-configuration was confirmed from an NOE correlation between H-2 of the indole moiety and H-2′ of the ribose moiety.
-
-
-
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27
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73249119901
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note
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When deprotection of the 5′-O-allyl group was examined after the introduction of the o-xylene phosphate units at the 2′, 3″, and 4″-hydroxyls, it was unsuccessful.
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