-
1
-
-
0034700643
-
High-density lipoprotein cholesterol as an independent risk factor in cardiovascular disease: Assessing the data from Framingham to the Veterans Affairs High-Density Lipoprotein Intervention Trial
-
Boden, W. E. 2000. High-density lipoprotein cholesterol as an independent risk factor in cardiovascular disease: assessing the data from Framingham to the Veterans Affairs High-Density Lipoprotein Intervention Trial. Am. J. Cardiol. 86: 19L-22L.
-
(2000)
Am. J. Cardiol
, vol.86
-
-
Boden, W.E.1
-
2
-
-
34447511196
-
Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women
-
Nordestgaard, B. G., M. Benn, P. Schnohr, and A. Tybjaerg-Hansen. 2007. Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women. JAMA. 298: 299-308.
-
(2007)
JAMA
, vol.298
, pp. 299-308
-
-
Nordestgaard, B.G.1
Benn, M.2
Schnohr, P.3
Tybjaerg-Hansen, A.4
-
3
-
-
33750213836
-
Cholesteryl ester transfer protein decreases high-density lipoprotein and severely aggravates atherosclerosis in APOE*3-Leiden mice
-
Westerterp, M., C. C. van der Hoogt, W. de Haan, E. H. Offerman, G. M. Dallinga-Thie, J. W. Jukema, L. M. Havekes, and P. C. Rensen. 2006. Cholesteryl ester transfer protein decreases high-density lipoprotein and severely aggravates atherosclerosis in APOE*3-Leiden mice. Arterioscler. Thromb. Vasc. Biol. 26: 2552-2559.
-
(2006)
Arterioscler. Thromb. Vasc. Biol
, vol.26
, pp. 2552-2559
-
-
Westerterp, M.1
van der Hoogt, C.C.2
de Haan, W.3
Offerman, E.H.4
Dallinga-Thie, G.M.5
Jukema, J.W.6
Havekes, L.M.7
Rensen, P.C.8
-
4
-
-
36348975228
-
Effects of torcetrapib in patients at high risk for coronary events
-
Barter, P. J., M. Caulfield, M. Eriksson, S. M. Grundy, J. J. Kastelein, M. Komajda, J. Lopez-Sendon, L. Mosca, J. C. Tardif, D. D. Waters, et al. 2007. Effects of torcetrapib in patients at high risk for coronary events. N. Engl. J. Med. 357: 2109-2122.
-
(2007)
N. Engl. J. Med
, vol.357
, pp. 2109-2122
-
-
Barter, P.J.1
Caulfield, M.2
Eriksson, M.3
Grundy, S.M.4
Kastelein, J.J.5
Komajda, M.6
Lopez-Sendon, J.7
Mosca, L.8
Tardif, J.C.9
Waters, D.D.10
-
5
-
-
58649091088
-
Efficacy and safety of the cholesteryl ester transfer protein inhibitor anacetrapib as monotherapy and coadministered with atorvastatin in dyslipidemic patients
-
Bloomfield, D., G. L. Carlson, A. Sapre, D. Tribble, J. M. McKenney, T. W. Littlejohn III, C. M. Sisk, Y. Mitchel, and R. C. Pasternak. 2009. Efficacy and safety of the cholesteryl ester transfer protein inhibitor anacetrapib as monotherapy and coadministered with atorvastatin in dyslipidemic patients. Am. Heart J. 157: 352-360.
-
(2009)
Am. Heart J
, vol.157
, pp. 352-360
-
-
Bloomfield, D.1
Carlson, G.L.2
Sapre, A.3
Tribble, D.4
McKenney, J.M.5
Littlejohn III, T.W.6
Sisk, C.M.7
Mitchel, Y.8
Pasternak, R.C.9
-
6
-
-
52949140241
-
JTT-705: Is there still future for a CETP inhibitor after torcetrapib?
-
Rennings, A. J., and A. F. Stalenhoef. 2008. JTT-705: is there still future for a CETP inhibitor after torcetrapib? Expert Opin. Investig. Drugs. 17: 1589-1597.
-
(2008)
Expert Opin. Investig. Drugs
, vol.17
, pp. 1589-1597
-
-
Rennings, A.J.1
Stalenhoef, A.F.2
-
7
-
-
12144287356
-
Raising high-density lipoprotein in humans through inhibition of cholesteryl ester transfer protein: An initial multidose study of torcetrapib
-
Clark, R. W., T. A. Sutfin, R. B. Ruggeri, A. T. Willauer, E. D. Sugarman, G. Magnus-Aryitey, P. G. Cosgrove, T. M. Sand, R. T. Wester, J. A. Williams, et al. 2004. Raising high-density lipoprotein in humans through inhibition of cholesteryl ester transfer protein: an initial multidose study of torcetrapib. Arterioscler. Thromb. Vasc. Biol. 24: 490-497.
-
(2004)
Arterioscler. Thromb. Vasc. Biol
, vol.24
, pp. 490-497
-
-
Clark, R.W.1
Sutfin, T.A.2
Ruggeri, R.B.3
Willauer, A.T.4
Sugarman, E.D.5
Magnus-Aryitey, G.6
Cosgrove, P.G.7
Sand, T.M.8
Wester, R.T.9
Williams, J.A.10
-
8
-
-
0037035459
-
Efficacy and safety of a novel cholesteryl ester transfer protein inhibitor, JTT-705, in humans: A randomized phase II dose-response study
-
de Grooth, G. J., J. A. Kuivenhoven, A. F. Stalenhoef, J. de Graaf, A. H. Zwinderman, J. L. Posma, A. van Tol, and J. J. Kastelein. 2002. Efficacy and safety of a novel cholesteryl ester transfer protein inhibitor, JTT-705, in humans: a randomized phase II dose-response study. Circulation. 105: 2159-2165.
-
(2002)
Circulation
, vol.105
, pp. 2159-2165
-
-
de Grooth, G.J.1
Kuivenhoven, J.A.2
Stalenhoef, A.F.3
de Graaf, J.4
Zwinderman, A.H.5
Posma, J.L.6
van Tol, A.7
Kastelein, J.J.8
-
9
-
-
57849131140
-
Cholesterylestertransfer protein inhibition and endothelial function in type II hyperlipidemia
-
Hermann, F., F. Enseleit, L. E. Spieker, D. Periat, I. Sudano, M. Hermann, R. Corti, G. Noll, F. Ruschitzka, and T. F. Luscher. 2009. Cholesterylestertransfer protein inhibition and endothelial function in type II hyperlipidemia. Thromb. Res. 123: 460-465.
-
(2009)
Thromb. Res
, vol.123
, pp. 460-465
-
-
Hermann, F.1
Enseleit, F.2
Spieker, L.E.3
Periat, D.4
Sudano, I.5
Hermann, M.6
Corti, R.7
Noll, G.8
Ruschitzka, F.9
Luscher, T.F.10
-
10
-
-
0038000630
-
Expression of human hepatic lipase in the rabbit model preferentially enhances the clearance of triglyceride-enriched versus native high-density lipoprotein apolipoprotein A-I
-
Rashid, S., D. K. Trinh, K. D. Uffelman, J. S. Cohn, D. J. Rader, and G. F. Lewis. 2003. Expression of human hepatic lipase in the rabbit model preferentially enhances the clearance of triglyceride-enriched versus native high-density lipoprotein apolipoprotein A-I. Circulation. 107: 3066-3072.
-
(2003)
Circulation
, vol.107
, pp. 3066-3072
-
-
Rashid, S.1
Trinh, D.K.2
Uffelman, K.D.3
Cohn, J.S.4
Rader, D.J.5
Lewis, G.F.6
-
11
-
-
0026451944
-
Dietary cholesterol increases transcription of the human cholesteryl ester transfer protein gene in transgenic mice. Dependence on natural flanking sequences
-
Jiang, X. C., L. B. Agellon, A. Walsh, J. L. Breslow, and A. Tall. 1992. Dietary cholesterol increases transcription of the human cholesteryl ester transfer protein gene in transgenic mice. Dependence on natural flanking sequences. J. Clin. Invest. 90: 1290-1295.
-
(1992)
J. Clin. Invest
, vol.90
, pp. 1290-1295
-
-
Jiang, X.C.1
Agellon, L.B.2
Walsh, A.3
Breslow, J.L.4
Tall, A.5
-
12
-
-
0027174832
-
Transgenic mice carrying the apolipoprotein E3-Leiden gene exhibit hyperlipoproteinemia
-
van den Maagdenberg, A. M., M. H. Hofker, P. J. Krimpenfort, I. de Bruijn, B. van Vlijmen, H. van der Boom, L. M. Havekes, and R. R. Frants. 1993. Transgenic mice carrying the apolipoprotein E3-Leiden gene exhibit hyperlipoproteinemia. J. Biol. Chem. 268: 10540-10545.
-
(1993)
J. Biol. Chem
, vol.268
, pp. 10540-10545
-
-
van den Maagdenberg, A.M.1
Hofker, M.H.2
Krimpenfort, P.J.3
de Bruijn, I.4
van Vlijmen, B.5
van der Boom, H.6
Havekes, L.M.7
Frants, R.R.8
-
13
-
-
13944253941
-
Severe hypertriglyceridemia in human APOC1 transgenic mice is caused by apoC-I-induced inhibition of LPL
-
Berbee, J. F., C. C. van der Hoogt, D. Sundararaman, L. M. Havekes, and P. C. Rensen. 2005. Severe hypertriglyceridemia in human APOC1 transgenic mice is caused by apoC-I-induced inhibition of LPL. J. Lipid Res. 46: 297-306.
-
(2005)
J. Lipid Res
, vol.46
, pp. 297-306
-
-
Berbee, J.F.1
van der Hoogt, C.C.2
Sundararaman, D.3
Havekes, L.M.4
Rensen, P.C.5
-
14
-
-
0026443622
-
Mechanism of hypertriglyceridemia in human apolipoprotein (apo) CIII transgenic mice. Diminished very low density lipoprotein fractional catabolic rate associated with increased apo CIII and reduced apo E on the particles
-
Aalto-Setala, K., E. A. Fisher, X. Chen, T. Chajek-Shaul, T. Hayek, R. Zechner, A. Walsh, R. Ramakrishnan, H. N. Ginsberg, and J. L. Breslow. 1992. Mechanism of hypertriglyceridemia in human apolipoprotein (apo) CIII transgenic mice. Diminished very low density lipoprotein fractional catabolic rate associated with increased apo CIII and reduced apo E on the particles. J. Clin. Invest. 90: 1889-1900.
-
(1992)
J. Clin. Invest
, vol.90
, pp. 1889-1900
-
-
Aalto-Setala, K.1
Fisher, E.A.2
Chen, X.3
Chajek-Shaul, T.4
Hayek, T.5
Zechner, R.6
Walsh, A.7
Ramakrishnan, R.8
Ginsberg, H.N.9
Breslow, J.L.10
-
15
-
-
0028891097
-
Very fast ultracentrifugation of serum lipoproteins: Influence on lipoprotein separation and composition
-
Pietzsch, J., S. Subat, S. Nitzsche, W. Leonhardt, K. U. Schentke, and M. Hanefeld. 1995. Very fast ultracentrifugation of serum lipoproteins: influence on lipoprotein separation and composition. Biochim. Biophys. Acta. 1254: 77-88.
-
(1995)
Biochim. Biophys. Acta
, vol.1254
, pp. 77-88
-
-
Pietzsch, J.1
Subat, S.2
Nitzsche, S.3
Leonhardt, W.4
Schentke, K.U.5
Hanefeld, M.6
-
16
-
-
0030032986
-
Method to measure apolipoprotein B-48 and B-100 secretion rates in an individual mouse: Evidence for a very rapid turnover of VLDL and preferential removal of B-48- relative to B-100-containing lipoproteins
-
Li, X., F. Catalina, S. M. Grundy, and S. Patel. 1996. Method to measure apolipoprotein B-48 and B-100 secretion rates in an individual mouse: evidence for a very rapid turnover of VLDL and preferential removal of B-48- relative to B-100-containing lipoproteins. J. Lipid Res. 37: 210-220.
-
(1996)
J. Lipid Res
, vol.37
, pp. 210-220
-
-
Li, X.1
Catalina, F.2
Grundy, S.M.3
Patel, S.4
-
17
-
-
0021062199
-
Isopropanol precipitation method for the determination of apolipoprotein B specific activity and plasma concentrations during metabolic studies of very low density lipoprotein and low density lipoprotein apolipoprotein B
-
Egusa, G., D. W. Brady, S. M. Grundy, and B. V. Howard. 1983. Isopropanol precipitation method for the determination of apolipoprotein B specific activity and plasma concentrations during metabolic studies of very low density lipoprotein and low density lipoprotein apolipoprotein B. J. Lipid Res. 24: 1261-1267.
-
(1983)
J. Lipid Res
, vol.24
, pp. 1261-1267
-
-
Egusa, G.1
Brady, D.W.2
Grundy, S.M.3
Howard, B.V.4
-
18
-
-
0031010389
-
Particle size determines the specificity of apolipoprotein E-containing triglyceride-rich emulsions for the LDL receptor versus hepatic remnant receptor in vivo
-
Rensen, P. C., N. Herijgers, M. H. Netscher, S. C. Meskers, M. van Eck, and T. J. van Berkel. 1997. Particle size determines the specificity of apolipoprotein E-containing triglyceride-rich emulsions for the LDL receptor versus hepatic remnant receptor in vivo. J. Lipid Res. 38: 1070-1084.
-
(1997)
J. Lipid Res
, vol.38
, pp. 1070-1084
-
-
Rensen, P.C.1
Herijgers, N.2
Netscher, M.H.3
Meskers, S.C.4
van Eck, M.5
van Berkel, T.J.6
-
19
-
-
0037343188
-
Contribution of fatty acids released from lipolysis of plasma triglycerides to total plasma fatty acid flux and tissue-specific fatty acid uptake
-
Teusink, B., P. J. Voshol, V. E. Dahlmans, P. C. Rensen, H. Pijl, J. A. Romijn, and L. M. Havekes. 2003. Contribution of fatty acids released from lipolysis of plasma triglycerides to total plasma fatty acid flux and tissue-specific fatty acid uptake. Diabetes. 52: 614-620.
-
(2003)
Diabetes
, vol.52
, pp. 614-620
-
-
Teusink, B.1
Voshol, P.J.2
Dahlmans, V.E.3
Rensen, P.C.4
Pijl, H.5
Romijn, J.A.6
Havekes, L.M.7
-
20
-
-
66449096933
-
Bexarotene induces dyslipidemia by increased VLDL production and cholesteryl ester transfer protein (CETP)-mediated reduction of HDL
-
de Vries-van der Weij, J., W. de Haan, L. Hu, M. Kuif, H. L. Oei, J. W. van der Hoorn, L. M. Havekes, H. M. Princen, J. A. Romijn, J. W. Smit, et al. 2009. Bexarotene induces dyslipidemia by increased VLDL production and cholesteryl ester transfer protein (CETP)-mediated reduction of HDL. Endocrinology. 150: 2368-2375.
-
(2009)
Endocrinology
, vol.150
, pp. 2368-2375
-
-
de Vries-van der Weij, J.1
de Haan, W.2
Hu, L.3
Kuif, M.4
Oei, H.L.5
van der Hoorn, J.W.6
Havekes, L.M.7
Princen, H.M.8
Romijn, J.A.9
Smit, J.W.10
-
21
-
-
0034708664
-
Apolipoprotein E is resistant to intracellular degradation in vitro and in vivo. Evidence for retroendocytosis
-
Rensen, P. C., M. C. Jong, L. C. van Vark, H. van der Boom, W. L. Hendriks, T. J. van Berkel, E. A. Biessen, and L. M. Havekes. 2000. Apolipoprotein E is resistant to intracellular degradation in vitro and in vivo. Evidence for retroendocytosis. J. Biol. Chem. 275: 8564-8571.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 8564-8571
-
-
Rensen, P.C.1
Jong, M.C.2
van Vark, L.C.3
van der Boom, H.4
Hendriks, W.L.5
van Berkel, T.J.6
Biessen, E.A.7
Havekes, L.M.8
-
22
-
-
67349153370
-
Effect of plasma triglyceride metabolism on lipid storage in adipose tissue: Studies using genetically engineered mouse models
-
Voshol, P. J., P. C. Rensen, K. W. van Dijk, J. A. Romijn, and L. M. Havekes. 2009. Effect of plasma triglyceride metabolism on lipid storage in adipose tissue: studies using genetically engineered mouse models. Biochim. Biophys. Acta. 1791: 479-485.
-
(2009)
Biochim. Biophys. Acta
, vol.1791
, pp. 479-485
-
-
Voshol, P.J.1
Rensen, P.C.2
van Dijk, K.W.3
Romijn, J.A.4
Havekes, L.M.5
-
23
-
-
34547624651
-
Mouse models for atherosclerosis and pharmaceutical modifiers
-
Zadelaar, S., R. Kleemann, L. Verschuren, J. de Vries-van der Weij, J. van der Hoorn, H. M. Princen, and T. Kooistra. 2007. Mouse models for atherosclerosis and pharmaceutical modifiers. Arterioscler. Thromb. Vasc. Biol. 27: 1706-1721.
-
(2007)
Arterioscler. Thromb. Vasc. Biol
, vol.27
, pp. 1706-1721
-
-
Zadelaar, S.1
Kleemann, R.2
Verschuren, L.3
de Vries-van der Weij, J.4
van der Hoorn, J.5
Princen, H.M.6
Kooistra, T.7
-
24
-
-
0035091953
-
ApoA-II expression in CETP transgenic mice increases VLDL production and impairs VLDL clearance
-
Escola-Gil, J. C., J. Julve, A. Marzal-Casacuberta, J. Ordonez-Llanos, F. Gonzalez-Sastre, and F. Blanco-Vaca. 2001. ApoA-II expression in CETP transgenic mice increases VLDL production and impairs VLDL clearance. J. Lipid Res. 42: 241-248.
-
(2001)
J. Lipid Res
, vol.42
, pp. 241-248
-
-
Escola-Gil, J.C.1
Julve, J.2
Marzal-Casacuberta, A.3
Ordonez-Llanos, J.4
Gonzalez-Sastre, F.5
Blanco-Vaca, F.6
-
25
-
-
64849101883
-
Cholesteryl ester transfer protein (CETP) increases postprandial triglyceridemia and delays triglyceride plasma clearance in transgenic mice
-
Salerno, A. G., P. R. Patricio, J. A. Berti, and H. C. Oliveira. 2009. Cholesteryl ester transfer protein (CETP) increases postprandial triglyceridemia and delays triglyceride plasma clearance in transgenic mice. Biochem. J. 419: 629-634.
-
(2009)
Biochem. J
, vol.419
, pp. 629-634
-
-
Salerno, A.G.1
Patricio, P.R.2
Berti, J.A.3
Oliveira, H.C.4
-
26
-
-
33947180987
-
CETP expression enhances liver HDL-cholesteryl ester uptake but does not alter VLDL and biliary lipid secretion
-
Harada, L. M., L. Amigo, P. M. Cazita, A. G. Salerno, A. A. Rigotti, E. C. Quintao, and H. C. Oliveira. 2007. CETP expression enhances liver HDL-cholesteryl ester uptake but does not alter VLDL and biliary lipid secretion. Atherosclerosis. 191: 313-318.
-
(2007)
Atherosclerosis
, vol.191
, pp. 313-318
-
-
Harada, L.M.1
Amigo, L.2
Cazita, P.M.3
Salerno, A.G.4
Rigotti, A.A.5
Quintao, E.C.6
Oliveira, H.C.7
-
27
-
-
0033560938
-
Triglyceride enrichment of HDL enhances in vivo metabolic clearance of HDL apo A-I in healthy men
-
Lamarche, B., K. D. Uffelman, A. Carpentier, J. S. Cohn, G. Steiner, P. H. Barrett, and G. F. Lewis. 1999. Triglyceride enrichment of HDL enhances in vivo metabolic clearance of HDL apo A-I in healthy men. J. Clin. Invest. 103: 1191-1199.
-
(1999)
J. Clin. Invest
, vol.103
, pp. 1191-1199
-
-
Lamarche, B.1
Uffelman, K.D.2
Carpentier, A.3
Cohn, J.S.4
Steiner, G.5
Barrett, P.H.6
Lewis, G.F.7
-
28
-
-
0028279771
-
Apolipoprotein A-I metabolism in cholesteryl ester transfer protein transgenic mice. Insights into the mechanisms responsible for low plasma high density lipoprotein levels
-
Melchior, G. W., C. K. Castle, R. W. Murray, W. L. Blake, D. M. Dinh, and K. R. Marotti. 1994. Apolipoprotein A-I metabolism in cholesteryl ester transfer protein transgenic mice. Insights into the mechanisms responsible for low plasma high density lipoprotein levels. J. Biol. Chem. 269: 8044-8051.
-
(1994)
J. Biol. Chem
, vol.269
, pp. 8044-8051
-
-
Melchior, G.W.1
Castle, C.K.2
Murray, R.W.3
Blake, W.L.4
Dinh, D.M.5
Marotti, K.R.6
-
29
-
-
0036120696
-
Lipolytically modified triglyceride-enriched HDLs are rapidly cleared from the circulation
-
Rashid, S., P. H. Barrett, K. D. Uffelman, T. Watanabe, K. Adeli, and G. F. Lewis. 2002. Lipolytically modified triglyceride-enriched HDLs are rapidly cleared from the circulation. Arterioscler. Thromb. Vasc. Biol. 22: 483-487.
-
(2002)
Arterioscler. Thromb. Vasc. Biol
, vol.22
, pp. 483-487
-
-
Rashid, S.1
Barrett, P.H.2
Uffelman, K.D.3
Watanabe, T.4
Adeli, K.5
Lewis, G.F.6
|