-
1
-
-
73149098229
-
-
Available from [Last accessed 31 January 2009]
-
World Diabetes Foundation. Available from: http://www. worlddiabetesfoundation.org/ composite-35.htm [Last accessed 31 January 2009]
-
-
-
-
2
-
-
73149111146
-
-
National Diabetes Information Clearinghouse. Available from [Last accessed 31 January 2009]
-
National Diabetes Information Clearinghouse. Available from: http://diabetes.niddk.nih.gov/dm/pubs/ statistics/#allages [Last accessed 31 January 2009]
-
-
-
-
3
-
-
0032511583
-
Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)
-
UK Prospective Diabetes Study (UKPDS) Group
-
UK Prospective Diabetes Study (UKPDS) Group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet 1998;352:837-853
-
(1998)
Lancet
, vol.352
, pp. 837-853
-
-
-
4
-
-
53749096863
-
Ten year follow up of intensive glucose control for type 2 diabetes mellitus
-
Holman RR, Paul SK, Bethel MA, et al. Ten year follow up of intensive glucose control for type 2 diabetes mellitus. N Engl J Med 2008;359;15:1577-1589
-
(2008)
N Engl J Med
, vol.359
, Issue.15
, pp. 1577-1589
-
-
Holman, R.R.1
Paul, S.K.2
Bethel, M.A.3
-
5
-
-
0029147687
-
Intensive insulin therapy prevents the progression of diabetic microvascular complications in Japanese patients with non-insulin dependent diabetes mellitus: A randomized prospective 6 year study
-
Ohkubo Y, Kishikawa H, Raki E, et al. Intensive insulin therapy prevents the progression of diabetic microvascular complications in Japanese patients with non-insulin dependent diabetes mellitus: a randomized prospective 6 year study. Diabetes Res Clin Pract 1995;28:103-117
-
(1995)
Diabetes Res Clin Pract
, vol.28
, pp. 103-117
-
-
Ohkubo, Y.1
Kishikawa, H.2
Raki, E.3
-
6
-
-
45149133036
-
Intensive blood glucose control and vascularoutcomes in patients with type 2 diabetes
-
The ADVANCE Collaborative Group
-
The ADVANCE Collaborative Group. Intensive blood glucose control and vascularoutcomes in patients with type 2 diabetes. N Engl J Med 2008;358:2560-2572
-
(2008)
N Engl J Med
, vol.358
, pp. 2560-2572
-
-
-
7
-
-
77957001439
-
Glucose control and vascular complications in veterans with type 2 diabetes
-
Duckworth W, Abraira C, Moritz T, et al. Glucose control and vascular complications in veterans with type 2 diabetes. N Engl J Med 2009;1:1-11
-
(2009)
N Engl J Med
, vol.1
, pp. 1-11
-
-
Duckworth, W.1
Abraira, C.2
Moritz, T.3
-
8
-
-
12844281026
-
Quality of diabetes care in US academic medical centers: Low rates of medical regimen change
-
Grant R, Buse JB, Meigs JB, et al. Quality of diabetes care in US academic medical centers: low rates of medical regimen change. Diabetes Care 2005;28;2:337-342
-
(2005)
Diabetes Care
, vol.28
, Issue.2
, pp. 337-342
-
-
Grant, R.1
Buse, J.B.2
Meigs, J.B.3
-
9
-
-
14744274123
-
Clinical inertia in response to inadequate glycemic control: Do specialists differ from primary care physicians?
-
Shah BR, Hux JE, Laupacis A. Clinical inertia in response to inadequate glycemic control: do specialists differ from primary care physicians? Diabetes Care 2005;28:600-606
-
(2005)
Diabetes Care
, vol.28
, pp. 600-606
-
-
Shah, B.R.1
Hux, J.E.2
Laupacis, A.3
-
10
-
-
73149124622
-
-
Available from [Last accessed 31 January 2009]
-
Centers for Disease Control Diabetes Fact Sheet. Available from: http://www.cdc. gov/diabetes/pubs/pdf/ndfs-2007.pdf [Last accessed 31 January 2009]
-
-
-
-
11
-
-
73149114501
-
-
American Diabetes Association. Available from Last accessed 31 January 2009
-
American Diabetes Association. Costs of Diabetes Care. Available from: http://www.diabetes.org/diabetes-statistics/ cost-of-diabetes-in-us.jsp [Last accessed 31 January 2009]
-
Costs of Diabetes Care
-
-
-
12
-
-
54949131340
-
National trends in the treatment of type 2 diabetes 1994-2007
-
Alexander GC, Schgal NL, Moloney RM. National trends in the treatment of type 2 diabetes: 1994 - 2007. Arch Int Med 2008;169:2088-2094
-
(2008)
Arch Int Med
, vol.169
, pp. 2088-2094
-
-
Alexander, G.C.1
Schgal, N.L.2
Moloney, R.M.3
-
13
-
-
60449089649
-
Medical management of hyperglycemia in type 2 diabetes: A consensus algorithm for the initiation and adjustment of therapy
-
A consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes
-
Nathan DM, Buse JB, Davidson MB. Medical management of hyperglycemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care 2009;32;1:193-203
-
(2009)
Diabetes Care
, vol.32
, Issue.1
, pp. 193-203
-
-
Nathan, D.M.1
Buse, J.B.2
Davidson, M.B.3
-
14
-
-
37349010670
-
-
AACE Diabetes Mellitus Clinical Practice Guideline Task Force. American Association of Clinical Endocrinologists Medical Guidelines for Management of Diabetes Mellitus
-
AACE Diabetes Mellitus Clinical Practice Guideline Task Force. American Association of Clinical Endocrinologists Medical Guidelines for Management of Diabetes Mellitus. Endocr Pract 2007;13(Suppl 1):3-68
-
(2007)
Endocr Pract
, vol.13
, Issue.SUPPL. 1
, pp. 3-68
-
-
-
15
-
-
34548609993
-
Systematic review: Comparative effectiveness and safety of oral medications for type 2 diabetes mellitus
-
Bolen S, Feldman L, Vassy J. Systematic review: comparative effectiveness and safety of oral medications for type 2 diabetes mellitus. Ann Int Med 2007;147:386-399
-
(2007)
Ann Int Med
, vol.147
, pp. 386-399
-
-
Bolen, S.1
Feldman, L.2
Vassy, J.3
-
16
-
-
33845468278
-
Dipeptidyl peptidase IV (DPP IV) inhibitors: A newly emerging drug class for the treatment of type 2 diabetes
-
Green B, Flatt P, Bailey C. Dipeptidyl peptidase IV (DPP IV) inhibitors: a newly emerging drug class for the treatment of type 2 diabetes. Diab Vasc Dis Res 2006;159-165
-
(2006)
Diab Vasc Dis Res
, pp. 159-165
-
-
Green, B.1
Flatt, P.2
Bailey, C.3
-
17
-
-
33947672273
-
Dipeptidyl peptidase IV inhibitors: The next generation of new promising therapies for the management of type 2 diabetes
-
Sebokova E, Christ A, Boehringer M, et al. Dipeptidyl peptidase IV inhibitors: the next generation of new promising therapies for the management of type 2 diabetes. Curr Top Med Chem 2006;7:547-555
-
(2006)
Curr Top Med Chem
, vol.7
, pp. 547-555
-
-
Sebokova, E.1
Christ, A.2
Boehringer, M.3
-
18
-
-
34047141757
-
Synthesis, biological evaluation and structural determination of beta-aminoacyl-containing cyclic hydrazine derivatives as dipeptidyl peptidase IV (DPP-IV) inhibitors
-
Ahn JH, Shin MS, Jun MA, et al. Synthesis, biological evaluation and structural determination of beta-aminoacyl-containing cyclic hydrazine derivatives as dipeptidyl peptidase IV (DPP-IV) inhibitors. Bioorg Med Chem Lett 2007;17:2622-2628
-
(2007)
Bioorg Med Chem Lett
, vol.17
, pp. 2622-2628
-
-
Ahn, J.H.1
Shin, M.S.2
Jun, M.A.3
-
19
-
-
33947705084
-
Molecular recognition of ligands in dipeptidyl peptidase IV
-
Kuhn B, Hennig M, Mattei P. Molecular recognition of ligands in dipeptidyl peptidase IV. Curr Top Med Chem 2007;7:609-619
-
(2007)
Curr Top Med Chem
, vol.7
, pp. 609-619
-
-
Kuhn, B.1
Hennig, M.2
Mattei, P.3
-
20
-
-
33947685466
-
11 years of cyanopyrrolidines as DPP-IV inhibitors
-
Peters JU. 11 years of cyanopyrrolidines as DPP-IV inhibitors. Curr Top Med Chem 2007;7:579-595
-
(2007)
Curr Top Med Chem
, vol.7
, pp. 579-595
-
-
Peters, J.U.1
-
21
-
-
33947686370
-
Prolyl peptidase related to dipeptidyl peptidase IV: Potential of specific inhibitors in drug discovery
-
Veken PV, Haemers A, Augustyns K. Prolyl peptidase related to dipeptidyl peptidase IV: potential of specific inhibitors in drug discovery. Curr Top Med Chem 2007;7:621-635
-
(2007)
Curr Top Med Chem
, vol.7
, pp. 621-635
-
-
Veken, P.V.1
Haemers, A.2
Augustyns, K.3
-
22
-
-
33947611932
-
Azetidine-based inhibitors of dipeptidyl peptidase IV (DPP IV)
-
Ferraris D, Belyakov S, Li W, et al. Azetidine-based inhibitors of dipeptidyl peptidase IV (DPP IV). Curr Top Med Chem 2007;7:597-608
-
(2007)
Curr Top Med Chem
, vol.7
, pp. 597-608
-
-
Ferraris, D.1
Belyakov, S.2
Li, W.3
-
23
-
-
73149118601
-
-
August, Bristol-Myers Squibb/ AstraZeneca
-
Onglyza (saxagliptin) package insert. August 2009. Bristol-Myers Squibb/ AstraZeneca
-
(2009)
Onglyza (Saxagliptin) Package Insert
-
-
-
24
-
-
84870754610
-
-
Available from [Last accessed 31 January 2009]
-
Cochrane database: Available from: http://mrw.interscience.wiley.com/ cochrane-clcentral-articles-fs.html [Last accessed 31 January 2009]
-
Cochrane Database
-
-
-
25
-
-
73149102871
-
-
Available from [Last accessed 31 January 2009]
-
Clinical trials.gov. Available from: http://clinicaltrials.gov/ct2/ results? term=saxagliptin [Last accessed 31 January 2009]
-
-
-
-
26
-
-
0033175006
-
Glucagon-like peptide 1(GLP-1): An intestinal hormone signaling nutritional abundance, with unusual therapeutic potential
-
Holst JJ. Glucagon-like peptide 1(GLP-1): an intestinal hormone signaling nutritional abundance, with unusual therapeutic potential. Trends Endocrinol Metab 1999;10:229-235
-
(1999)
Trends Endocrinol Metab
, vol.10
, pp. 229-235
-
-
Holst, J.J.1
-
27
-
-
17844362518
-
Dipeptidyl peptidase inhibitors as new drugs for the treatment of type 2 diabetes
-
Mest HJ, Mentlein R. Dipeptidyl peptidase inhibitors as new drugs for the treatment of type 2 diabetes. Diabetologia 2005;48:616-620
-
(2005)
Diabetologia
, vol.48
, pp. 616-620
-
-
Mest, H.J.1
Mentlein, R.2
-
28
-
-
34447267513
-
Efficacy and safety of incretin therapy in type 2 diabetes: Systematic review and meta-analysis
-
DOI 10.1001/jama.298.2.194
-
Amori RE, Lau J, Pittas AG. Efficacy and safety of incretin therapy in type 2 diabetes. Systematic review and meta-analysis. JAMA 2007;298:194-206 (Pubitemid 47057766)
-
(2007)
Journal of the American Medical Association
, vol.298
, Issue.2
, pp. 194-206
-
-
Amori, R.E.1
Lau, J.2
Pittas, A.G.3
-
29
-
-
45949094989
-
Managed care perspective on three new agents for type 2 diabetes
-
VanDeKoppel S, Choe HM, Sweet BV. Managed care perspective on three new agents for type 2 diabetes. J Manag Care Pharm 2008;14:363-380
-
(2008)
J Manag Care Pharm
, vol.14
, pp. 363-380
-
-
Vandekoppel, S.1
Choe, H.M.2
Sweet, B.V.3
-
30
-
-
53049091868
-
Dipeptidyl peptidase-4 as a new target of action for type 2 diabetes mellitus: A systematic review
-
Wani JH, John-Kalarickal J, Fonseca VA. Dipeptidyl peptidase-4 as a new target of action for type 2 diabetes mellitus: a systematic review. Cardiol Clin 2008;26:639-648
-
(2008)
Cardiol Clin
, vol.26
, pp. 639-648
-
-
Wani, J.H.1
John-Kalarickal, J.2
Fonseca, V.A.3
-
31
-
-
42949178414
-
DPP-IV inhibitors: A review of sitagliptin, vildagliptin, alogliptin, and saxagliptin
-
Miller SA, St Onge EL, Taylor JR. DPP-IV inhibitors: a review of sitagliptin, vildagliptin, alogliptin, and saxagliptin. Formulary 2008;43:122-134
-
(2008)
Formulary
, vol.43
, pp. 122-134
-
-
Miller, S.A.1
St Onge, E.L.2
Taylor, J.R.3
-
32
-
-
65549123794
-
Saxagliptin given in combination with metformin as initial therapy improves glycaemic control in patients with type diabetes compared with either monotherapy: A randomized controlled trial
-
for CV181-039 Investigators
-
Jadinsky M, Pfutzner A, Paz-Pacheco E, et al.; for CV181-039 Investigators. Saxagliptin given in combination with metformin as initial therapy improves glycaemic control in patients with type diabetes compared with either monotherapy: a randomized controlled trial. Diabetes Obes Metab 2009;11:611-622
-
(2009)
Diabetes Obes Metab
, vol.11
, pp. 611-622
-
-
Jadinsky, M.1
Pfutzner, A.2
Paz-Pacheco, E.3
-
33
-
-
22744449063
-
Discovery and preclinical profile of saxagliptin (BMS-477118): A highly potent, long acting, orally active dipeptidyl pepitdase IV inhibitor of type 2 diabetes
-
Augeri DJ, Robl JA, Betebenner DA, et al. Discovery and preclinical profile of saxagliptin (BMS-477118): a highly potent, long acting, orally active dipeptidyl pepitdase IV inhibitor of type 2 diabetes. J Med Chem 2005;48:5025-5037
-
(2005)
J Med Chem
, vol.48
, pp. 5025-5037
-
-
Augeri, D.J.1
Robl, J.A.2
Betebenner, D.A.3
-
34
-
-
38649109776
-
Involvement of DPP-IV catalytic residues in enzyme saxagliptin complex formation
-
Metzler WJ, Yanchunas J, Weigelt C, et al. Involvement of DPP-IV catalytic residues in enzyme saxagliptin complex formation. Protein Sci 2008;17:240-250
-
(2008)
Protein Sci
, vol.17
, pp. 240-250
-
-
Metzler, W.J.1
Yanchunas, J.2
Weigelt, C.3
-
35
-
-
23644440644
-
Diprolyl nitriles as potent dipeptidyl pepitase IV inhibitors
-
Zhao G, Taunk PC, Magnin DR, et al. Diprolyl nitriles as potent dipeptidyl pepitase IV inhibitors. Bioorg Med Chem Lett 2005;15:3992-3995
-
(2005)
Bioorg Med Chem Lett
, vol.15
, pp. 3992-3995
-
-
Zhao, G.1
Taunk, P.C.2
Magnin, D.R.3
-
36
-
-
69549135336
-
The efficacy and safety of saxagliptin when added to metformin therapy in patients with inadequately controlled type 2 diabetes with metformin alone
-
Defronzo RA, Hissa M, Barber A, et al. The efficacy and safety of saxagliptin when added to metformin therapy in patients with inadequately controlled type 2 diabetes with metformin alone. Diabetes Care 2009;32:1649-1655
-
(2009)
Diabetes Care
, vol.32
, pp. 1649-1655
-
-
Defronzo, R.A.1
Hissa, M.2
Barber, A.3
-
37
-
-
73149106690
-
Safety, tolerability, pharmacokinetics of a once-daily oral doses of saxagliptin for 2 weeks in type 2 diabetic and healthy subjects [abstract 606-P]
-
Presented at Orlando FL, USA
-
Boulton DW, Geraldes M. Safety, tolerability, pharmacokinetics of a once-daily oral doses of saxagliptin for 2 weeks in type 2 diabetic and healthy subjects [abstract 606-P]. Presented at the 67th American Diabetes Association Scientific Sessions 2007 Orlando FL, USA
-
(2007)
The 67th American Diabetes Association Scientific Sessions
-
-
Boulton, D.W.1
Geraldes, M.2
-
39
-
-
70349333861
-
Effect of saxagliptin montherapy in treatment naive patients with type 2 diabetes
-
Rosenstock J, Aguilar-Salinas C, Klein E, et al. Effect of saxagliptin montherapy in treatment naive patients with type 2 diabetes. Curr Med Res Opin 2009;25:2401-2411
-
(2009)
Curr Med Res Opin
, vol.25
, pp. 2401-2411
-
-
Rosenstock, J.1
Aguilar-Salinas, C.2
Klein, E.3
-
40
-
-
76349117322
-
Once-daily saxaglipitin added to metformin provides sustained glycemic control and is well tolerated over 102 weeks in patients with type 2 diabetes mellitus
-
Abstract presented at
-
DeFronzo R, Hissa MN, Garber AJ, et al. Once-daily saxaglipitin added to metformin provides sustained glycemic control and is well tolerated over 102 weeks in patients with type 2 diabetes mellitus. Abstract presented at the 69th Scientific Sessions of the American Diabetes Association 2009
-
(2009)
The 69th Scientific Sessions of the American Diabetes Association
-
-
Defronzo, R.1
Hissa, M.N.2
Garber, A.J.3
-
41
-
-
73149084956
-
For the CV181-013 Investigators. Saxagliptin added to a thiazolidinedione improves glycemic control in patients with type 2 diabetes and inadequate control on thiazolidinedione alone
-
in press
-
Hollander P, Li J, Allen E, Chen R; for the CV181-013 Investigators. Saxagliptin added to a thiazolidinedione improves glycemic control in patients with type 2 diabetes and inadequate control on thiazolidinedione alone. J Clin Endocrinol Metab 2009, in press
-
(2009)
J Clin Endocrinol Metab
-
-
Hollander, P.1
Li, J.2
Allen, E.3
Chen, R.4
-
42
-
-
79952714842
-
Saxagliptin used as monotherapy or in combination with other antihyperglycemic agents does not significantly increase risk of hypoglycemia
-
Abstract presented at
-
Chen R, Dononvan M, Rusnak JM. Saxagliptin used as monotherapy or in combination with other antihyperglycemic agents does not significantly increase risk of hypoglycemia. Abstract presented at the 69th Scientific Sessions of the American Diabetes Association, 2009
-
(2009)
The 69th Scientific Sessions of the American Diabetes Association
-
-
Chen, R.1
Dononvan, M.2
Rusnak, J.M.3
-
43
-
-
56749105553
-
No pharmacokinetic interaction between saxagliptin and digoxin in healthy subject
-
Abstract presented at 2-5 Apr Orlando, FL, USA. Clin Pharmacol Ther 2008
-
Boulton DW, Li L, Patel CG, et al. No pharmacokinetic interaction between saxagliptin and digoxin in healthy subject. Abstract presented at the American Society for Clinical Pharmacology and Therapeutics Annual Meeting; 2-5 Apr 2008 Orlando, FL, USA. Clin Pharmacol Ther 2008;83:S93
-
(2008)
The American Society for Clinical Pharmacology and Therapeutics Annual Meeting
, vol.83
-
-
Boulton, D.W.1
Li, L.2
Patel, C.G.3
-
44
-
-
73149102870
-
The effects of age and gender on the single-dose pharmacokinetics and safety of saxagliptin in healthy subjects
-
Presented at
-
Boulton DW, Goyal A, Li L, et al. The effects of age and gender on the single-dose pharmacokinetics and safety of saxagliptin in healthy subjects. Presented at 68th Scientific Sessions of the American Diabetes Association 2008;57 (S1):A164
-
(2008)
68th Scientific Sessions of the American Diabetes Association
, vol.57
, Issue.S1
-
-
Boulton, D.W.1
Goyal, A.2
Li, L.3
-
45
-
-
73149108511
-
The influence of renal impairment on the pharmacokinetics of saxagliptin
-
Presented at American Society for Clinical Pharmacology and Therapeutics Annual Meeting; 18-21 Mar 2009, National Harbour MD, USA
-
Boulton DW, Tang A, Patel CG, et al. The influence of renal impairment on the pharmacokinetics of saxagliptin. Presented at American Society for Clinical Pharmacology and Therapeutics Annual Meeting; 18-21 Mar 2009, National Harbour MD, USA. Clin Pharmacol Ther 2009;85:S96
-
(2009)
Clin Pharmacol Ther
, vol.85
-
-
Boulton, D.W.1
Tang, A.2
Patel, C.G.3
-
46
-
-
42149194313
-
Glucose-lowering activity of the dipeptidyl peptidase-4 inhibitor saxagliptin in drug-naive patients with type 2 diabetes
-
Rosenstock J, Sankoh S, List JF, et al. Glucose-lowering activity of the dipeptidyl peptidase-4 inhibitor saxagliptin in drug-naive patients with type 2 diabetes. Diabetes Obes Metab 2008;10:376-386
-
(2008)
Diabetes Obes Metab
, vol.10
, pp. 376-386
-
-
Rosenstock, J.1
Sankoh, S.2
List, J.F.3
-
47
-
-
84912120338
-
No meaningful pharmacokinetic drug- drug interactions between saxagliptin and pioglitazone in healthy subjects [abstract 226]
-
Presented at 14-17Oct2007,Denver,CO,USA
-
Patel CG, Wolf RA, Komoroski B, et al. No meaningful pharmacokinetic drug- drug interactions between saxagliptin and pioglitazone in healthy subjects [abstract 226]. Presented at the American College of Clinical Pharmacy (ACCP) Annual Meeting;14-17Oct2007,Denver,CO,USA
-
The American College of Clinical Pharmacy (ACCP) Annual Meeting
-
-
Patel, C.G.1
Wolf, R.A.2
Komoroski, B.3
-
48
-
-
84912120338
-
No meaningful pharmacokinetic drug-drug interactions between saxagliptin and glyburide in healthy subjects [abstract 212]
-
Presented at 14-17 Oct 2007, Denver, CO, USA
-
Patel CG, Li L, Komoroski B, et al. No meaningful pharmacokinetic drug-drug interactions between saxagliptin and glyburide in healthy subjects [abstract 212]. Presented at the American College of Clinical Pharmacy (ACCP) Annual Meeting; 14-17 Oct 2007, Denver, CO, USA
-
The American College of Clinical Pharmacy (ACCP) Annual Meeting
-
-
Patel, C.G.1
Li, L.2
Komoroski, B.3
-
49
-
-
84912120338
-
No meaningful pharmacokinetic drug-drug interactions between saxagliptin and metformin in healthy subjects [abstract 213]
-
Presented at 14-17 Oct 2007, Denver, CO, USA
-
Patel CG, Komoroski B, Brenner E, et al. No meaningful pharmacokinetic drug-drug interactions between saxagliptin and metformin in healthy subjects [abstract 213]. Presented at the American College of Clinical Pharmacy (ACCP) Annual Meeting; 14-17 Oct 2007, Denver, CO, USA
-
The American College of Clinical Pharmacy (ACCP) Annual Meeting
-
-
Patel, C.G.1
Komoroski, B.2
Brenner, E.3
-
50
-
-
73449095647
-
Single dose pharmacokinetics and safety of saxagliptin in subjects with hepatic impairment compared with healthy subjects [abstract 537-P]
-
Presented at
-
Patel C, Castaneda L, Frevert U, et al. Single dose pharmacokinetics and safety of saxagliptin in subjects with hepatic impairment compared with healthy subjects [abstract 537-P]. Presented at 68th Scientific Sessions of the American Diabetes Association 2008
-
(2008)
68th Scientific Sessions of the American Diabetes Association
-
-
Patel, C.1
Castaneda, L.2
Frevert, U.3
-
51
-
-
42149194313
-
Glucose-lowering activity of the dipeptidyl peptidase-4 inhibitor saxagliptin in drug -naive patients with type 2 diabetes
-
Rosenstock J, Sankoh S, List JF. Glucose-lowering activity of the dipeptidyl peptidase-4 inhibitor saxagliptin in drug -naive patients with type 2 diabetes. Diabetes Obes Metab 2008;10:376-386
-
(2008)
Diabetes Obes Metab
, vol.10
, pp. 376-386
-
-
Rosenstock, J.1
Sankoh, S.2
List, J.F.3
-
52
-
-
73149096360
-
The new science of GLP-1: Effects beyond glucose control
-
Pratley RE. The new science of GLP-1: effects beyond glucose control. Johns Hopkins Adv Stud Med 2008;8;393-399
-
(2008)
Johns Hopkins Adv Stud Med
, vol.8
, pp. 393-399
-
-
Pratley, R.E.1
-
53
-
-
22644440448
-
Beta-cell preservation: A potential role for thiazolidinedione to improve clinical care in type 2 diabetes
-
Leiter LA. Beta-cell preservation: a potential role for thiazolidinedione to improve clinical care in type 2 diabetes. Diabet Med 2005;22:963-972
-
(2005)
Diabet Med
, vol.22
, pp. 963-972
-
-
Leiter, L.A.1
-
54
-
-
33751240059
-
A diabetes outcome progression trial (ADOPT): Baseline characteristics of type 2 diabetic patients in North America and Europe
-
Viberti G, Lachin J, Holman R, et al. A diabetes outcome progression trial (ADOPT): baseline characteristics of type 2 diabetic patients in North America and Europe. Diabet Med 2006;23:1289-1294
-
(2006)
Diabet Med
, vol.23
, pp. 1289-1294
-
-
Viberti, G.1
Lachin, J.2
Holman, R.3
-
55
-
-
33644762010
-
Effects of pioglitazone on pancreatic B-cell function and diabetes risk in hispanic women with prior gestational diabetes
-
Xiang AH, Peters RK, Kjos SL, et al. Effects of pioglitazone on pancreatic B-cell function and diabetes risk in hispanic women with prior gestational diabetes. Diabetes 2006;55:517-522
-
(2006)
Diabetes
, vol.55
, pp. 517-522
-
-
Xiang, A.H.1
Peters, R.K.2
Kjos, S.L.3
-
56
-
-
0037097039
-
Acarbose for prevention of type 2 diabetes mellitus: The STOP-NIDDM randomised trial
-
Chiasson JL, Josse RG, Gomis R, et al. Acarbose for prevention of type 2 diabetes mellitus: the STOP-NIDDM randomised trial. Lancet 2002;359:2072-2077
-
(2002)
Lancet
, vol.359
, pp. 2072-2077
-
-
Chiasson, J.L.1
Josse, R.G.2
Gomis, R.3
-
57
-
-
53049091868
-
Dipeptidal peptidase-4 as a new target of action for type 2 diabetes mellitus: A systematic review
-
Wani J, John-Kalarickal J, Fonseca V. Dipeptidal peptidase-4 as a new target of action for type 2 diabetes mellitus: a systematic review. Cardiol Clin 2008;26:639-648
-
(2008)
Cardiol Clin
, vol.26
, pp. 639-648
-
-
Wani, J.1
John-Kalarickal, J.2
Fonseca, V.3
-
58
-
-
33751009626
-
Exenatide in type 2 diabetes: Treatment effects in clinical studies and animal study data
-
Gallwitz B. Exenatide in type 2 diabetes: treatment effects in clinical studies and animal study data. Int J Clin Pract 2006;60:1654-1661
-
(2006)
Int J Clin Pract
, vol.60
, pp. 1654-1661
-
-
Gallwitz, B.1
-
59
-
-
2542479899
-
Mini review: Glucagon-like peptides regulate cell proliferation and apoptosis in the pancreas, gut, and central nervous system
-
Brubaker PL, Drucker DJ. Mini review: glucagon-like peptides regulate cell proliferation and apoptosis in the pancreas, gut, and central nervous system. Endocrinology 2004;145:2653-2659
-
(2004)
Endocrinology
, vol.145
, pp. 2653-2659
-
-
Brubaker, P.L.1
Drucker, D.J.2
|