Minimal RNA aptamer sequences that can inhibit or alleviate noncompetitive inhibition of the muscle-type nicotinic acetylcholine receptor

Journal of Membrane Biology

Volumn 233, Issue 1-3, 2010, Pages 1-12

  Sivaprakasam, Kannan ^a,b   Pagán, Oné R ^a,c   Hess, George P ^a  

^a 216 Biotechnology Building ^*  (United States)

^b ST CLOUD STATE UNIVERSITY   (United States)

^c WEST CHESTER UNIVERSITY   (United States)

Author keywords

Aptamer; Cocaine; Deoxyribonucleic acid; MK 801 (+) dizocilpine; Nicotinic acetylcholine receptor; Phencyclidine; Ribonucleic acid; Systematic evolution of ligands by exponential enrichment (SELEX); Whole cell current recording

Indexed keywords

APTAMER; DIZOCILPINE; NICOTINIC RECEPTOR;

ANIMAL CELL; ARTICLE; COMBINATORIAL CHEMISTRY; DRUG MECHANISM; DRUG RECEPTOR BINDING; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; RNA SEQUENCE;

ANIMALS; APTAMERS, NUCLEOTIDE; BASE SEQUENCE; CELL LINE; COCAINE; DIZOCILPINE MALEATE; KINETICS; MICE; MODELS, THEORETICAL; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; RECEPTORS, NICOTINIC;

MAMMALIA;

EID: 73049102146     PISSN: 00222631     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00232-009-9215-z     Document Type: Article

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