A conserved negatively charged cluster in the active site of creatine kinase is critical for enzymatic activity

Journal of Biological Chemistry

Volumn 275, Issue 35, 2000, Pages 27094-27099

  Eder, Michael ^a   Stolz, Martin ^a,b   Wallimann, Theo ^a   Schlattner, Uwe ^a  

^a ETH ZURICH   (Switzerland)

^b Central Laboratory in Bern   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CREATINE KINASE; MUTANT PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME KINETICS; ENZYME PURIFICATION; ENZYME STABILITY; ENZYME STRUCTURE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS;

BINDING SITES; CIRCULAR DICHROISM; CREATINE KINASE; DNA PRIMERS; HUMANS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; SPECTROPHOTOMETRY, ULTRAVIOLET; SUBSTRATE SPECIFICITY;

ESCHERICHIA COLI;

EID: 0034282672     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M004071200     Document Type: Article

References (37)