Hsp104 is essential for the selective degradation in yeast of polyglutamine expanded ataxin-1 but not most misfolded proteins generally

Biochemical and Biophysical Research Communications

Volumn 391, Issue 1, 2010, Pages 1056-1061

  Lee, Do Hee ^a   Goldberg, Alfred L ^b  

^a Seoul Women University   (South Korea)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Ataxin 1; Hsp104; Molecular chaperones; Polyglutamine; Proteasomes

Indexed keywords

ATAXIN 1; CELL PROTEIN; HEAT SHOCK PROTEIN 104; MUTANT PROTEIN; POLYGLUTAMINE; PROTEASOME;

ARTICLE; CONTROLLED STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN STABILITY; SOLUBILITY; STRAIN DIFFERENCE; WILD TYPE; YEAST;

HEAT-SHOCK PROTEINS; HUMANS; MUTATION; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; PEPTIDES; PROTEIN FOLDING; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 72949118877     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.12.018     Document Type: Article

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