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Volumn 12, Issue 4, 2009, Pages 215-220

Immunopathogenesis of multiple sclerosis

Author keywords

Magnetic resonance imaging; Multiple sclerosis; Pathogenesis; Review

Indexed keywords

IMMUNOGLOBULIN G; MYELIN ASSOCIATED GLYCOPROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA AGONIST; PROTEIN NOGO;

EID: 72949116951     PISSN: 09722327     EISSN: 19983549     Source Type: Journal    
DOI: 10.4103/0972-2327.58274     Document Type: Review
Times cited : (17)

References (47)
  • 1
    • 33644607018 scopus 로고    scopus 로고
    • Multiple sclerosis-the plaque and its pathogenesis
    • Frohman EM, Racke MK, Raine CS. Multiple sclerosis-the plaque and its pathogenesis. N Engl J Med 2006;354:942-955
    • (2006) N Engl J Med , vol.354 , pp. 942-955
    • Frohman, E.M.1    Racke, M.K.2    Raine, C.S.3
  • 2
    • 25144520110 scopus 로고    scopus 로고
    • Characterizing the mechanisms of progression in multiple sclerosis: Evidence and new hypotheses for future directions
    • Frohman EM, Filippi M, Stuve O, Waxman SG, Corboy J, Phillips JT, et al. Characterizing the mechanisms of progression in multiple sclerosis: Evidence and new hypotheses for future directions. Arch Neurol 2005;62:1345-1356
    • (2005) Arch Neurol , vol.62 , pp. 1345-1356
    • Frohman, E.M.1    Filippi, M.2    Stuve, O.3    Waxman, S.G.4    Corboy, J.5    Phillips, J.T.6
  • 3
    • 2642572423 scopus 로고    scopus 로고
    • The pathogenesis and basis for treatment in multiple sclerosis
    • Compston A. The pathogenesis and basis for treatment in multiple sclerosis. Clin Neurol Neurosurg 2004;106:246-248
    • (2004) Clin Neurol Neurosurg , vol.106 , pp. 246-248
    • Compston, A.1
  • 4
    • 0037225363 scopus 로고    scopus 로고
    • Are astrocytes central players in the pathophysiology of multiple sclerosis?
    • De Keyser J, Zeinstra E, Frohman E. Are astrocytes central players in the pathophysiology of multiple sclerosis? Arch Neurol 2003;60:132-136
    • (2003) Arch Neurol , vol.60 , pp. 132-136
    • De Keyser, J.1    Zeinstra, E.2    Frohman, E.3
  • 5
    • 0032519421 scopus 로고    scopus 로고
    • Decreased dependence of myelin basic protein-reactive T cells on CD28-mediated costimulation in multiple sclerosis patients: A marker of activated/memory T cells
    • Lovett-Racke AE, Trotter JL, Lauber J, Perrin PJ, June CH, Racke MK. Decreased dependence of myelin basic protein-reactive T cells on CD28-mediated costimulation in multiple sclerosis patients: A marker of activated/memory T cells. J Clin Invest 1998;101:725-730
    • (1998) J Clin Invest , vol.101 , pp. 725-730
    • Lovett-Racke, A.E.1    Trotter, J.L.2    Lauber, J.3    Perrin, P.J.4    June, C.H.5    Racke, M.K.6
  • 8
    • 34248659946 scopus 로고    scopus 로고
    • The CD8 T cell in multiple sclerosis: Suppressor cell or mediator of neuropathology?
    • Johnson AJ, Suidan GL, McDole J, Pirko I. The CD8 T cell in multiple sclerosis: Suppressor cell or mediator of neuropathology? Int Rev Neurobiol 2007;79:73-97.
    • (2007) Int Rev Neurobiol , vol.79 , pp. 73-97
    • Johnson, A.J.1    Suidan, G.L.2    McDole, J.3    Pirko, I.4
  • 9
    • 34548133584 scopus 로고    scopus 로고
    • Multiple sclerosis: A complicated picture of autoimmunity
    • McFarland HF, Martin R. Multiple sclerosis: A complicated picture of autoimmunity. Nat Immunol 2007;8:913-919
    • (2007) Nat Immunol , vol.8 , pp. 913-919
    • McFarland, H.F.1    Martin, R.2
  • 11
    • 1642281535 scopus 로고    scopus 로고
    • Relapsing and remitting multiple sclerosis: Pathology of the newly forming lesion
    • Barnett MH, Prineas JW. Relapsing and remitting multiple sclerosis: Pathology of the newly forming lesion. Ann Neurol 2004;55:458-468
    • (2004) Ann Neurol , vol.55 , pp. 458-468
    • Barnett, M.H.1    Prineas, J.W.2
  • 12
    • 34548299105 scopus 로고    scopus 로고
    • Risk alleles for multiple sclerosis Identified by a genomewide study
    • International Multiple Sclerosis Genetics Consortium
    • International Multiple Sclerosis Genetics Consortium. Risk alleles for multiple sclerosis Identified by a genomewide study. N Engl J Med 2007;357:851-862
    • (2007) N Engl J Med , vol.357 , pp. 851-862
  • 13
    • 34249781999 scopus 로고    scopus 로고
    • Pathogenesis of axonal and neuronal damage in multiple sclerosis
    • discussion S43-54
    • Dutta R, Trapp BD. Pathogenesis of axonal and neuronal damage in multiple sclerosis. Neurology 2007;68:S22-31; discussion S43-54.
    • (2007) Neurology , vol.68
    • Dutta, R.1    Trapp, B.D.2
  • 14
    • 0032576636 scopus 로고    scopus 로고
    • Demyelinating diseases - New pathological insights, new therapeutic targets
    • Waxman SG. Demyelinating diseases--new pathological insights, new therapeutic targets. N Engl J Med 1998;338:323-325
    • (1998) N Engl J Med , vol.338 , pp. 323-325
    • Waxman, S.G.1
  • 15
    • 0032796747 scopus 로고    scopus 로고
    • Axonal pathology in multiple sclerosis: Relationship to neurologic disability
    • DOI 10.1097/00019052-199906000-00008
    • Trapp BD, Ransohoff R, Rudick R. Axonal pathology in multiple sclerosis: Relationship to neurologic disability. Curr Opin Neurol 1999;12:295-302. (Pubitemid 29378163)
    • (1999) Current Opinion in Neurology , vol.12 , Issue.3 , pp. 295-302
    • Trapp, B.D.1    Ransohoff, R.2    Rudick, R.3
  • 16
    • 28044462637 scopus 로고    scopus 로고
    • Axonal injury in early multiple sclerosis is irreversible and independent of the short-term disease evolution
    • Rovaris M, Gambini A, Gallo A, Falini A, Ghezzi A, Benedetti B, et al. Axonal injury in early multiple sclerosis is irreversible and independent of the short-term disease evolution. Neurology 2005;65:1626-1630
    • (2005) Neurology , vol.65 , pp. 1626-1630
    • Rovaris, M.1    Gambini, A.2    Gallo, A.3    Falini, A.4    Ghezzi, A.5    Benedetti, B.6
  • 17
    • 38549149965 scopus 로고    scopus 로고
    • Disinhibition of neurite growth to repair the injured adult CNS: Focusing on Nogo
    • Gonzenbach RR, Schwab ME. Disinhibition of neurite growth to repair the injured adult CNS: Focusing on Nogo. Cell Mol Life Sci 2008;65:161-176
    • (2008) Cell Mol Life Sci , vol.65 , pp. 161-176
    • Gonzenbach, R.R.1    Schwab, M.E.2
  • 19
    • 0036158610 scopus 로고    scopus 로고
    • Oligodendrocyte precursor cells in the demyelinated multiple sclerosis spinal cord
    • Wolswijk G. Oligodendrocyte precursor cells in the demyelinated multiple sclerosis spinal cord. Brain 2002;125:338-349
    • (2002) Brain , vol.125 , pp. 338-349
    • Wolswijk, G.1
  • 20
    • 0036799650 scopus 로고    scopus 로고
    • Multiple sclerosis: Re-expression of a developmental pathway that restricts oligodendrocyte maturation
    • John GR, Shankar SL, Shafit-Zagardo B, Massimi A, Lee SC, Raine CS, et al. Multiple sclerosis: Re-expression of a developmental pathway that restricts oligodendrocyte maturation. Nat Med 2002;8:1115-1121
    • (2002) Nat Med , vol.8 , pp. 1115-1121
    • John, G.R.1    Shankar, S.L.2    Shafit-Zagardo, B.3    Massimi, A.4    Lee, S.C.5    Raine, C.S.6
  • 21
    • 34548206670 scopus 로고    scopus 로고
    • Astrocytes - Friends or foes in multiple sclerosis?
    • Williams A, Piaton G, Lubetzki C. Astrocytes--friends or foes in multiple sclerosis? Glia 2007;55:1300-1312
    • (2007) Glia , vol.55 , pp. 1300-1312
    • Williams, A.1    Piaton, G.2    Lubetzki, C.3
  • 22
    • 38749143286 scopus 로고    scopus 로고
    • Interleukin-17 production in central nervous systemin filtrating T cells and glial cells is associated with active disease in multiple sclerosis
    • Tzartos JS, Friese MA, Craner MJ, Palace J, Newcombe J, Esiri MM, et al. Interleukin-17 production in central nervous systemin filtrating T cells and glial cells is associated with active disease in multiple sclerosis. Am J Pathol 2008;172:146-155
    • (2008) Am J Pathol , vol.172 , pp. 146-155
    • Tzartos, J.S.1    Friese, M.A.2    Craner, M.J.3    Palace, J.4    Newcombe, J.5    Esiri, M.M.6
  • 23
    • 40449089827 scopus 로고    scopus 로고
    • Differential regulation of central nervous system autoimmunity by T(H)1 and T(H)17 cells
    • Stromnes IM, Cerretti LM, Liggitt D, Harris RA, Goverman JM. Differential regulation of central nervous system autoimmunity by T(H)1 and T(H)17 cells. Nat Med 2008;14:337-342
    • (2008) Nat Med , vol.14 , pp. 337-342
    • Stromnes, I.M.1    Cerretti, L.M.2    Liggitt, D.3    Harris, R.A.4    Goverman, J.M.5
  • 25
    • 61749093508 scopus 로고    scopus 로고
    • IL-17A and IL-17F do not contribute vitally to autoimmune neuro-inß ammation in mice
    • Haak S, Croxford AL, Dreymborg K, Heppner FL, Pouly S, Becher B, et al. IL-17A and IL-17F do not contribute vitally to autoimmune neuro-inß ammation in mice. J Clin Invest 2009;119:61-69
    • (2009) J Clin Invest , vol.119 , pp. 61-69
    • Haak, S.1    Croxford, A.L.2    Dreymborg, K.3    Heppner, F.L.4    Pouly, S.5    Becher, B.6
  • 26
    • 10744223596 scopus 로고    scopus 로고
    • The utility of MRI in suspected MS: Report of the therapeutics and technology assessment subcommittee of the American academy of neurology
    • Frohman EM, Goodin DS, Calabresi PA, Corboy JR, Coyle PK, Filippi M, et al. The utility of MRI in suspected MS: Report of the therapeutics and technology assessment subcommittee of the American academy of neurology. Neurology 2003;61:602-611
    • (2003) Neurology , vol.61 , pp. 602-611
    • Frohman, E.M.1    Goodin, D.S.2    Calabresi, P.A.3    Corboy, J.R.4    Coyle, P.K.5    Filippi, M.6
  • 27
    • 27744571428 scopus 로고    scopus 로고
    • Update on multiple sclerosis
    • Simon JH. Update on multiple sclerosis. Radiol Clin North Am 2006;44:79-100.
    • (2006) Radiol Clin North Am , vol.44 , pp. 79-100
    • Simon, J.H.1
  • 28
  • 29
    • 34248643430 scopus 로고    scopus 로고
    • Neuroimaging in multiple sclerosis
    • Zivadinov R, Cox JL. Neuroimaging in multiple sclerosis. Int Rev Neurobiol 2007;79:449-474.
    • (2007) Int Rev Neurobiol , vol.79 , pp. 449-474
    • Zivadinov, R.1    Cox, J.L.2
  • 30
    • 34147186825 scopus 로고    scopus 로고
    • Magnetization transfer MRI in multiple sclerosis
    • DOI 10.1111/j.1552-6569.2007.00132.x
    • Filippi M, Agosta F. Magnetization transfer MRI in multiple sclerosis. J Neuroimaging 2007;17:22S-6S. (Pubitemid 46558264)
    • (2007) Journal of Neuroimaging , vol.17 , Issue.SUPPL. 1
    • Filippi, M.1    Agosta, F.2
  • 31
    • 34147180059 scopus 로고    scopus 로고
    • Diffusion tensor MRI in multiple sclerosis
    • DOI 10.1111/j.1552-6569.2007.00133.x
    • Rovaris M, Filippi M. Diffusion tensor MRI in multiple sclerosis. J Neuroimaging 2007;17:27S-30S. (Pubitemid 46558265)
    • (2007) Journal of Neuroimaging , vol.17 , Issue.SUPPL. 1
    • Rovaris, M.1    Filippi, M.2
  • 32
    • 33749489506 scopus 로고    scopus 로고
    • Grey matter damage predicts the evolution of primary progressive multiple sclerosis at 5 years
    • Rovaris M, Judica E, Gallo A, Benedetti B, Sormani MP, Caputo D, et al. Grey matter damage predicts the evolution of primary progressive multiple sclerosis at 5 years. Brain 2006;129:2628-2634
    • (2006) Brain , vol.129 , pp. 2628-2634
    • Rovaris, M.1    Judica, E.2    Gallo, A.3    Benedetti, B.4    Sormani, M.P.5    Caputo, D.6
  • 33
    • 34147189667 scopus 로고    scopus 로고
    • MR spectroscopy in multiple sclerosis
    • De Stefano N, Filippi M. MR spectroscopy in multiple sclerosis. J Neuroimaging 2007;17:31S-5S.
    • (2007) J Neuroimaging , vol.17
    • De Stefano, N.1    Filippi, M.2
  • 34
    • 1842608971 scopus 로고    scopus 로고
    • Indirect evidence for early widespread gray matter involvement in relapsing-remitting multiple sclerosis
    • Inglese M, Ge Y, Filippi M, Falini A, Grossman RI, Gonen O. Indirect evidence for early widespread gray matter Involvement in relapsing-remitting multiple sclerosis. Neuroimage 2004;21:1825-1829
    • (2004) Neuroimage , vol.21 , pp. 1825-1829
    • Inglese, M.1    Ge, Y.2    Filippi, M.3    Falini, A.4    Grossman, R.I.5    Gonen, O.6
  • 35
    • 36448937869 scopus 로고    scopus 로고
    • Optical coherence tomography and disease subtype in multiple sclerosis
    • DOI 10.1212/01.wnl.0000294876.49861.dc, PII 0000611420071127000010
    • Pulicken M, Gordon-Lipkin E, Balcer LJ, Frohman E, Cutter G, Calabresi PA. Optical coherence tomography and disease subtype in multiple sclerosis. Neurology 2007;69:2085-2092 (Pubitemid 350175711)
    • (2007) Neurology , vol.69 , Issue.22 , pp. 2085-2092
    • Pulicken, M.1    Gordon-Lipkin, E.2    Balcer, L.J.3    Frohman, E.4    Cutter, G.5    Calabresi, P.A.6
  • 37
    • 34147129201 scopus 로고    scopus 로고
    • Functional MRI in multiple sclerosis
    • Rocca MA, Filippi M. Functional MRI in multiple sclerosis. J Neuroimaging 2007;17:36S-41S.
    • (2007) J Neuroimaging , vol.17
    • Rocca, M.A.1    Filippi, M.2
  • 40
    • 40349116787 scopus 로고    scopus 로고
    • Betaseron vs. copaxone in MS with triple-dose gadolinium and 3-T MRI Endpoints (BECOME): Announcement of final primary study outcome
    • Presented at: Prague Czech Republic
    • Wolansky L. Betaseron vs. copaxone in MS with triple-dose gadolinium and 3-T MRI Endpoints (BECOME): Announcement of final primary study outcome. Presented at: 23rd congress of the European committee for treatment and research in multiple sclerosis (ECTRIMS). Prague, Czech Republic: 2007.
    • (2007) 23rd Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS)
    • Wolansky, L.1
  • 41
    • 33846459970 scopus 로고    scopus 로고
    • Soluble Nogo-A, an inhibitor of axonal regeneration, as a biomarker for multiple sclerosis
    • Jurewicz A, Matysiak M, Raine CS, Selmaj K. Soluble Nogo-A, an inhibitor of axonal regeneration, as a biomarker for multiple sclerosis. Neurology 2007;68:283-287
    • (2007) Neurology , vol.68 , pp. 283-287
    • Jurewicz, A.1    Matysiak, M.2    Raine, C.S.3    Selmaj, K.4
  • 42
    • 39849101009 scopus 로고    scopus 로고
    • Proteomic analysis of active multiple sclerosis lesions reveals therapeutic targets
    • Han MH, Hwang SI, Roy DB, Lundgren DH, Price JV, Ousman SS, et al. Proteomic analysis of active multiple sclerosis lesions reveals therapeutic targets. Nature 2008;451:1076-1081
    • (2008) Nature , vol.451 , pp. 1076-1081
    • Han, M.H.1    Hwang, S.I.2    Roy, D.B.3    Lundgren, D.H.4    Price, J.V.5    Ousman, S.S.6
  • 43
    • 0026506799 scopus 로고
    • Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha 4 beta 1 integrin
    • Yednock TA, Cannon C, Fritz LC, Sanchez-Madrid F, Steinman L, Karin N. Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha 4 beta 1 integrin. Nature 1992;356:63-66
    • (1992) Nature , vol.356 , pp. 63-66
    • Yednock, T.A.1    Cannon, C.2    Fritz, L.C.3    Sanchez-Madrid, F.4    Steinman, L.5    Karin, N.6
  • 45
    • 33847122993 scopus 로고    scopus 로고
    • Dual PPAR alpha/gamma agonists: Promises and pitfalls in type 2 diabetes
    • Ahmed I, Furlong K, Flood J, Treat VP, Goldstein BJ. Dual PPAR alpha/gamma agonists: Promises and pitfalls in type 2 diabetes. Am J Ther 2007;14:49-62.
    • (2007) Am J Ther , vol.14 , pp. 49-62
    • Ahmed, I.1    Furlong, K.2    Flood, J.3    Treat, V.P.4    Goldstein, B.J.5
  • 46
    • 0036499074 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-γ agonist 15-deoxy-Δ 12, 14-PGJ2 ameliorates experimental autoimmune encephalomyelitis
    • Diab A, Deng C, Smith JD, Hussain RZ, Phanavanh B, Lovett-Racke AE, et al. Peroxisome proliferator-activated receptor-γ agonist 15-deoxy-Δ 12, 14-PGJ2 ameliorates experimental autoimmune encephalomyelitis. J Immunol 2002;168:2508-2515
    • (2002) J Immunol , vol.168 , pp. 2508-2515
    • Diab, A.1    Deng, C.2    Smith, J.D.3    Hussain, R.Z.4    Phanavanh, B.5    Lovett-Racke, A.E.6


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