Hypermethylation of the IGF2 differentially methylated region 2 is a specific event in insulinomas leading to loss-of-imprinting and overexpression

Endocrine-Related Cancer

Volumn 16, Issue 3, 2009, Pages 939-952

  Dejeux, Emelyne ^a   Olaso, Robert ^a   Dousset, Bertrand ^b   Audebourg, Anne ^b,c   Gut, Ivo G ^a   Terris, Benoit ^b,c,d   Tost, Jörg ^a  

^a CENTRE NATIONAL DE GÉNOTYPAGE   (France)

^b Université Paris Descartes ^*  (France)

^c INSTITUT COCHIN   (France)

^d INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

DIFFERENTIALLY METHYLATED REGION 2; GENE PRODUCT; SOMATOMEDIN B; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CANCER CLASSIFICATION; CANCER STAGING; CONTROLLED STUDY; CPG ISLAND; DISEASE MARKER; DNA METHYLATION; FEMALE; GASTRINOMA; GENE LOCATION; GENE OVEREXPRESSION; GENE SEQUENCE; GENOME IMPRINTING; HUMAN; INSULINOMA; MAJOR CLINICAL STUDY; MALE; PANCREAS ISLET CELL TUMOR; PROMOTER REGION;

ADULT; AGED; DNA METHYLATION; FEMALE; GASTRINOMA; GENE EXPRESSION REGULATION, NEOPLASTIC; GENOMIC IMPRINTING; HUMANS; INSULIN-LIKE GROWTH FACTOR II; INSULINOMA; MALE; MIDDLE AGED; ORGAN SPECIFICITY; PANCREATIC NEOPLASMS; PROMOTER REGIONS, GENETIC; RNA, UNTRANSLATED; TUMOR MARKERS, BIOLOGICAL; UP-REGULATION; YOUNG ADULT;

EID: 72749102458     PISSN: 13510088     EISSN: 14796821     Source Type: Journal    
DOI: 10.1677/ERC-08-0331     Document Type: Article

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