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Volumn 93, Issue 1, 2010, Pages 141-149

Polymorphisms of estrogen-related genes jointly confer susceptibility to human spermatogenic defect

Author keywords

Estrogen; estrogen receptor; male infertility; spermatogenic defect

Indexed keywords

AROMATASE; CATECHOL METHYLTRANSFERASE; CYTOCHROME P450 17; CYTOCHROME P450 1A1; CYTOCHROME P450 1B1; ESTROGEN; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA;

EID: 72749096034     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2008.09.030     Document Type: Article
Times cited : (26)

References (57)
  • 4
    • 0033305438 scopus 로고    scopus 로고
    • Estrogen receptor null mice: what have we learned and where will they lead us?
    • Couse J.F., and Korach K.S. Estrogen receptor null mice: what have we learned and where will they lead us?. Endocr Rev 20 (1999) 358-417
    • (1999) Endocr Rev , vol.20 , pp. 358-417
    • Couse, J.F.1    Korach, K.S.2
  • 5
    • 0032130696 scopus 로고    scopus 로고
    • Regulation of gene expression during spermatogenesis
    • Eddy E.M. Regulation of gene expression during spermatogenesis. Semin Cell Dev Biol 9 (1998) 451-457
    • (1998) Semin Cell Dev Biol , vol.9 , pp. 451-457
    • Eddy, E.M.1
  • 6
    • 34548049525 scopus 로고    scopus 로고
    • The effects of oestrogen receptors {alpha} and {beta} on testicular cell number and steroidogenesis in mice
    • Gould M.L., Hurst P.R., and Nicholson H.D. The effects of oestrogen receptors {alpha} and {beta} on testicular cell number and steroidogenesis in mice. Reproduction 134 (2007) 271-279
    • (2007) Reproduction , vol.134 , pp. 271-279
    • Gould, M.L.1    Hurst, P.R.2    Nicholson, H.D.3
  • 7
    • 0029969771 scopus 로고    scopus 로고
    • Targeted disruption of the estrogen receptor gene in male mice causes alteration of spermatogenesis and infertility
    • Eddy E.M., Washburn T.F., Bunch D.O., Goulding E.H., Gladen B.C., Lubahn D.B., et al. Targeted disruption of the estrogen receptor gene in male mice causes alteration of spermatogenesis and infertility. Endocrinology 137 (1996) 4796-4805
    • (1996) Endocrinology , vol.137 , pp. 4796-4805
    • Eddy, E.M.1    Washburn, T.F.2    Bunch, D.O.3    Goulding, E.H.4    Gladen, B.C.5    Lubahn, D.B.6
  • 8
    • 0031039888 scopus 로고    scopus 로고
    • Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta
    • Kuiper G.G., Carlsson B., Grandien K., Enmark E., Haggblad J., Nilsson S., et al. Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta. Endocrinology 138 (1997) 863-870
    • (1997) Endocrinology , vol.138 , pp. 863-870
    • Kuiper, G.G.1    Carlsson, B.2    Grandien, K.3    Enmark, E.4    Haggblad, J.5    Nilsson, S.6
  • 11
    • 10744225853 scopus 로고    scopus 로고
    • Dysmetabolic syndrome in a man with a novel mutation of the aromatase gene: effects of testosterone, alendronate, and estradiol treatment
    • Maffei L., Murata Y., Rochira V., Tubert G., Aranda C., Vazquez M., et al. Dysmetabolic syndrome in a man with a novel mutation of the aromatase gene: effects of testosterone, alendronate, and estradiol treatment. J Clin Endocrinol Metab 89 (2004) 61-70
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 61-70
    • Maffei, L.1    Murata, Y.2    Rochira, V.3    Tubert, G.4    Aranda, C.5    Vazquez, M.6
  • 13
    • 34250788800 scopus 로고    scopus 로고
    • Male infertility: role of genetic background
    • Ferlin A. Male infertility: role of genetic background. Reprod BioMed Online 14 (2007) 734-745
    • (2007) Reprod BioMed Online , vol.14 , pp. 734-745
    • Ferlin, A.1
  • 14
    • 32644436182 scopus 로고    scopus 로고
    • Transgenic mice expressing p450 aromatase as a model for male infertility associated with chronic inflammation in the testis
    • Li X., Strauss L., Kaatrasalo A., Mayerhofer A., Huhtaniemi I., Santti R., et al. Transgenic mice expressing p450 aromatase as a model for male infertility associated with chronic inflammation in the testis. Endocrinology 147 (2006) 1271-1277
    • (2006) Endocrinology , vol.147 , pp. 1271-1277
    • Li, X.1    Strauss, L.2    Kaatrasalo, A.3    Mayerhofer, A.4    Huhtaniemi, I.5    Santti, R.6
  • 16
    • 33645294099 scopus 로고    scopus 로고
    • Estrogen receptor alpha promoter polymorphism: stronger estrogen action is coupled with lower sperm count
    • Guarducci E., Nuti F., Becherini L., Rotondi M., Balercia G., Forti G., et al. Estrogen receptor alpha promoter polymorphism: stronger estrogen action is coupled with lower sperm count. Hum Reprod 21 (2006) 994-1001
    • (2006) Hum Reprod , vol.21 , pp. 994-1001
    • Guarducci, E.1    Nuti, F.2    Becherini, L.3    Rotondi, M.4    Balercia, G.5    Forti, G.6
  • 17
    • 26244431698 scopus 로고    scopus 로고
    • Multilocus analyses of estrogen-related genes reveal involvement of the ESR1 gene in male infertility and the polygenic nature of the pathology
    • Galan J.J., Buch B., Cruz N., Segura A., Moron F.J., Bassas L., et al. Multilocus analyses of estrogen-related genes reveal involvement of the ESR1 gene in male infertility and the polygenic nature of the pathology. Fertil Steril 84 (2005) 910-918
    • (2005) Fertil Steril , vol.84 , pp. 910-918
    • Galan, J.J.1    Buch, B.2    Cruz, N.3    Segura, A.4    Moron, F.J.5    Bassas, L.6
  • 18
    • 0036247892 scopus 로고    scopus 로고
    • Gene-based screening for Y chromosome deletions in Taiwanese men presenting with spermatogenic failure
    • Lin Y.M., Lin Y.H., Teng Y.N., Hsu C.C., Kuo P.L., and Shinn-Nan L. Gene-based screening for Y chromosome deletions in Taiwanese men presenting with spermatogenic failure. Fertil Steril 77 (2002) 897-903
    • (2002) Fertil Steril , vol.77 , pp. 897-903
    • Lin, Y.M.1    Lin, Y.H.2    Teng, Y.N.3    Hsu, C.C.4    Kuo, P.L.5    Shinn-Nan, L.6
  • 19
    • 0029130796 scopus 로고
    • Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population
    • Excoffier L., and Slatkin M. Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population. Mol Biol Evol 12 (1995) 921-927
    • (1995) Mol Biol Evol , vol.12 , pp. 921-927
    • Excoffier, L.1    Slatkin, M.2
  • 20
    • 0036155283 scopus 로고    scopus 로고
    • Score tests for association between traits and haplotypes when linkage phase is ambiguous
    • Schaid D.J., Rowland C.M., Tines D.E., Jacobson R.M., and Poland G.A. Score tests for association between traits and haplotypes when linkage phase is ambiguous. Am J Hum Genet 70 (2002) 425-434
    • (2002) Am J Hum Genet , vol.70 , pp. 425-434
    • Schaid, D.J.1    Rowland, C.M.2    Tines, D.E.3    Jacobson, R.M.4    Poland, G.A.5
  • 24
    • 1642391717 scopus 로고    scopus 로고
    • Estrogen receptor (ER) alpha and ER beta are both expressed in human ejaculated spermatozoa: evidence of their direct interaction with phosphatidylinositol-3-OH kinase/Akt pathway
    • Aquila S., Sisci D., Gentile M., Middea E., Catalano S., Carpino A., et al. Estrogen receptor (ER) alpha and ER beta are both expressed in human ejaculated spermatozoa: evidence of their direct interaction with phosphatidylinositol-3-OH kinase/Akt pathway. J Clin Endocrinol Metab 89 (2004) 1443-1451
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 1443-1451
    • Aquila, S.1    Sisci, D.2    Gentile, M.3    Middea, E.4    Catalano, S.5    Carpino, A.6
  • 25
    • 0036903463 scopus 로고    scopus 로고
    • Estrogen receptor alpha gene polymorphism is associated with idiopathic azoospermia
    • Suzuki Y., Sasagawa I., Itoh K., Ashida J., Muroya K., and Ogata T. Estrogen receptor alpha gene polymorphism is associated with idiopathic azoospermia. Fertil Steril 78 (2002) 1341-1343
    • (2002) Fertil Steril , vol.78 , pp. 1341-1343
    • Suzuki, Y.1    Sasagawa, I.2    Itoh, K.3    Ashida, J.4    Muroya, K.5    Ogata, T.6
  • 26
    • 23844471536 scopus 로고    scopus 로고
    • Association of cryptorchidism with a specific haplotype of the estrogen receptor gene: implication for the susceptibility to estrogenic environmental endocrine disruptors
    • Yoshida R., Fukami M., Sasagawa I., Hasegawa T., Kamatani N., and Ogata T. Association of cryptorchidism with a specific haplotype of the estrogen receptor gene: implication for the susceptibility to estrogenic environmental endocrine disruptors. J Clin Endocrinol Metab 90 (2005) 4716-4721
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 4716-4721
    • Yoshida, R.1    Fukami, M.2    Sasagawa, I.3    Hasegawa, T.4    Kamatani, N.5    Ogata, T.6
  • 27
    • 33846480134 scopus 로고    scopus 로고
    • Molecular analysis of estrogen receptor alpha gene AGATA haplotype and SNP12 in European populations: potential protective effect for cryptorchidism and lack of association with male infertility
    • Galan J.J., Guarducci E., Nuti F., Gonzalez A., Ruiz M., Ruiz A., et al. Molecular analysis of estrogen receptor alpha gene AGATA haplotype and SNP12 in European populations: potential protective effect for cryptorchidism and lack of association with male infertility. Hum Reprod 22 (2006) 444-449
    • (2006) Hum Reprod , vol.22 , pp. 444-449
    • Galan, J.J.1    Guarducci, E.2    Nuti, F.3    Gonzalez, A.4    Ruiz, M.5    Ruiz, A.6
  • 28
    • 0028662025 scopus 로고    scopus 로고
    • Cytochromes P450 in the rat and man: methods of investigation, substrate specificities, and relevance to cancer
    • Watanabe M., Yoshida R., Ueoka K., Aoki K., Sasagawa I., Hasegawa T., et al. Cytochromes P450 in the rat and man: methods of investigation, substrate specificities, and relevance to cancer. Xenobiotica 24 (2007) 1151-1175
    • (2007) Xenobiotica , vol.24 , pp. 1151-1175
    • Watanabe, M.1    Yoshida, R.2    Ueoka, K.3    Aoki, K.4    Sasagawa, I.5    Hasegawa, T.6
  • 30
    • 0038100188 scopus 로고    scopus 로고
    • Modulation of oestrogen receptor signaling by association with the activated dioxin receptor
    • Ohtake F., Takeyana K.I., Mstsumoto T., Kitagawa H., Yamamoto Y., Nohara K., et al. Modulation of oestrogen receptor signaling by association with the activated dioxin receptor. Nature 423 (2003) 545-550
    • (2003) Nature , vol.423 , pp. 545-550
    • Ohtake, F.1    Takeyana, K.I.2    Mstsumoto, T.3    Kitagawa, H.4    Yamamoto, Y.5    Nohara, K.6
  • 31
    • 33750874054 scopus 로고    scopus 로고
    • Serum dioxin-lie activity is associated with reproductive parameters in young men from the central Flemish population
    • Dhooge W., van Larebeke N., Koppen G., Nelen V., Schoeters G., Vlietinck R., et al. Serum dioxin-lie activity is associated with reproductive parameters in young men from the central Flemish population. Environ Health Perspect 114 (2006) 1670-1676
    • (2006) Environ Health Perspect , vol.114 , pp. 1670-1676
    • Dhooge, W.1    van Larebeke, N.2    Koppen, G.3    Nelen, V.4    Schoeters, G.5    Vlietinck, R.6
  • 32
    • 33645808470 scopus 로고    scopus 로고
    • Effects of estrogenic xenobiotics on human and mouse spermatozoa
    • Fraser L.R., Beyret E., Milligan S.R., and Adeoya-Osiguwa S.A. Effects of estrogenic xenobiotics on human and mouse spermatozoa. Hum Reprod 21 (2006) 1184-1193
    • (2006) Hum Reprod , vol.21 , pp. 1184-1193
    • Fraser, L.R.1    Beyret, E.2    Milligan, S.R.3    Adeoya-Osiguwa, S.A.4
  • 33
    • 34548426537 scopus 로고    scopus 로고
    • Effect of genistein on acrosome reaction and zona pellucida binding independent of protein tyrosine kinase inhibition in bull
    • Menzel V.A., Hinsch E., Hägele W., and Hinsch K.D. Effect of genistein on acrosome reaction and zona pellucida binding independent of protein tyrosine kinase inhibition in bull. Asian J Androl 9 (2007) 650-658
    • (2007) Asian J Androl , vol.9 , pp. 650-658
    • Menzel, V.A.1    Hinsch, E.2    Hägele, W.3    Hinsch, K.D.4
  • 34
  • 35
    • 0028662025 scopus 로고    scopus 로고
    • P450 in the rat and man: methods of investigation, substrate specificities and relevance to cancer
    • Nedelcheva V., and Gut I. P450 in the rat and man: methods of investigation, substrate specificities and relevance to cancer. Xenobiotica 24 (1994) 1151-1175
    • (1994) Xenobiotica , vol.24 , pp. 1151-1175
    • Nedelcheva, V.1    Gut, I.2
  • 36
    • 0037140675 scopus 로고    scopus 로고
    • Genetic modelling of the estrogen metabolism as a risk factor of hormone-dependent disorders
    • Huber J.C., Schneeberger C., and Tempfer C.B. Genetic modelling of the estrogen metabolism as a risk factor of hormone-dependent disorders. Maturitus 42 (2002) 1-12
    • (2002) Maturitus , vol.42 , pp. 1-12
    • Huber, J.C.1    Schneeberger, C.2    Tempfer, C.B.3
  • 37
    • 0028109671 scopus 로고
    • Indolo[3,2-b] carbazole: a dietary derived factor that exhibits both antiestrogenic and estrogenic activity
    • Liu H., Wormke M., Safe S.H., and Bjeldanes L.F. Indolo[3,2-b] carbazole: a dietary derived factor that exhibits both antiestrogenic and estrogenic activity. J Natl Cancer Inst 86 (1994) 1758-1765
    • (1994) J Natl Cancer Inst , vol.86 , pp. 1758-1765
    • Liu, H.1    Wormke, M.2    Safe, S.H.3    Bjeldanes, L.F.4
  • 38
    • 0030043650 scopus 로고    scopus 로고
    • Effect of transient expression of the estrogen receptor on constitutive and inducible CYP1A1 in Hs578T human breast cancer cells
    • Wang W.L., Thomsen J.S., Porter W., Moore M., and Safe S. Effect of transient expression of the estrogen receptor on constitutive and inducible CYP1A1 in Hs578T human breast cancer cells. Br J Cancer 73 (1996) 316-322
    • (1996) Br J Cancer , vol.73 , pp. 316-322
    • Wang, W.L.1    Thomsen, J.S.2    Porter, W.3    Moore, M.4    Safe, S.5
  • 39
    • 85046912622 scopus 로고    scopus 로고
    • Environment, lifestyle and infertility-an inter-generational issue
    • Sharpe R.M., and Franks S. Environment, lifestyle and infertility-an inter-generational issue. Nat Cell Biol Suppl: (2002) s33-s40
    • (2002) Nat Cell Biol , Issue.SUPPL
    • Sharpe, R.M.1    Franks, S.2
  • 40
    • 33745262607 scopus 로고    scopus 로고
    • The sensitivity of the child to sex steroids: possible impact of exogenous estrogens
    • Aksglaede L., Juul A., Leffers H., Skakkebæk N.E., and Andersson1 A.M. The sensitivity of the child to sex steroids: possible impact of exogenous estrogens. Hum Reprod Update 12 (2006) 341-349
    • (2006) Hum Reprod Update , vol.12 , pp. 341-349
    • Aksglaede, L.1    Juul, A.2    Leffers, H.3    Skakkebæk, N.E.4    Andersson1, A.M.5
  • 41
    • 0038013585 scopus 로고    scopus 로고
    • Hydroxysteroid dehydrogenases and pre-receptor regulation of steroid hormone action
    • Penning T.M. Hydroxysteroid dehydrogenases and pre-receptor regulation of steroid hormone action. Hum Reprod Update 9 (2003) 193-205
    • (2003) Hum Reprod Update , vol.9 , pp. 193-205
    • Penning, T.M.1
  • 42
    • 34848829864 scopus 로고    scopus 로고
    • A new polymorphism in the coding region of exon four in HSD17B2 in relation to risk of sporadic and hereditary breast cancer
    • Jansson A., Carlsson J., Olsson A., Storm P., Margolin S., Gunnarsson C., et al. A new polymorphism in the coding region of exon four in HSD17B2 in relation to risk of sporadic and hereditary breast cancer. Breast Cancer Res Treat 106 (2007) 57-64
    • (2007) Breast Cancer Res Treat , vol.106 , pp. 57-64
    • Jansson, A.1    Carlsson, J.2    Olsson, A.3    Storm, P.4    Margolin, S.5    Gunnarsson, C.6
  • 43
    • 0016008573 scopus 로고
    • Sex-hormone-binding globulin
    • Anderson D.C. Sex-hormone-binding globulin. Clin Endocrinol (Oxf) 3 (1974) 69-96
    • (1974) Clin Endocrinol (Oxf) , vol.3 , pp. 69-96
    • Anderson, D.C.1
  • 44
    • 2942683102 scopus 로고    scopus 로고
    • Polymorphisms associated with circulating sex hormone levels in postmenopausal women
    • Dunning A.M., Dowsett M., Healey C.S., Tee L., Luben R.N., Folkerd E., et al. Polymorphisms associated with circulating sex hormone levels in postmenopausal women. J Natl Cancer Inst 96 (2004) 936-945
    • (2004) J Natl Cancer Inst , vol.96 , pp. 936-945
    • Dunning, A.M.1    Dowsett, M.2    Healey, C.S.3    Tee, L.4    Luben, R.N.5    Folkerd, E.6
  • 45
    • 12244301593 scopus 로고    scopus 로고
    • Associations of sex-hormone-binding globulin (SHBG) with non-SHBG-bound levels of testosterone and estradiol in independently living men
    • de Ronde W., van der Schouw Y.T., Muller M., Grobbee D.E., Gooren L.J., Pols H.A., et al. Associations of sex-hormone-binding globulin (SHBG) with non-SHBG-bound levels of testosterone and estradiol in independently living men. J Clin Endocrinol Metab 90 (2005) 157-162
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 157-162
    • de Ronde, W.1    van der Schouw, Y.T.2    Muller, M.3    Grobbee, D.E.4    Gooren, L.J.5    Pols, H.A.6
  • 46
    • 17044397684 scopus 로고    scopus 로고
    • Serum levels of sex hormone-binding globulin (SHBG) are not associated with lower levels of non-SHBG-bound testosterone in male newborns and healthy adult men
    • de Ronde W., van der Schouw Y.T., Pierik F.H., Pols H.A.P., Muller M., Grobbee D.E., et al. Serum levels of sex hormone-binding globulin (SHBG) are not associated with lower levels of non-SHBG-bound testosterone in male newborns and healthy adult men. Clin Endocrinol 62 (2005) 498-503
    • (2005) Clin Endocrinol , vol.62 , pp. 498-503
    • de Ronde, W.1    van der Schouw, Y.T.2    Pierik, F.H.3    Pols, H.A.P.4    Muller, M.5    Grobbee, D.E.6
  • 47
    • 27744546145 scopus 로고    scopus 로고
    • Human sperm sex hormone-binding globulin isoform: characterization and measurement by time-resolved fluorescence immunoassay
    • Selva D.M., Bassas L., Munell F., Mata A., Tekpetey F., Lewis J.G., et al. Human sperm sex hormone-binding globulin isoform: characterization and measurement by time-resolved fluorescence immunoassay. J Clin Endocrinol Metab 90 (2005) 6275-6282
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 6275-6282
    • Selva, D.M.1    Bassas, L.2    Munell, F.3    Mata, A.4    Tekpetey, F.5    Lewis, J.G.6
  • 48
    • 7044246174 scopus 로고    scopus 로고
    • Intratesticular testosterone concentrations comparable with serum levels are not sufficient to maintain normal sperm production in men receiving a hormone contraceptive regimen
    • Coviello A.D., Bremmer W.J., Mastumoto A.M., Herbst K.L., Amory J.K., Anawalt B.D., et al. Intratesticular testosterone concentrations comparable with serum levels are not sufficient to maintain normal sperm production in men receiving a hormone contraceptive regimen. J Androl 25 (2004) 931-938
    • (2004) J Androl , vol.25 , pp. 931-938
    • Coviello, A.D.1    Bremmer, W.J.2    Mastumoto, A.M.3    Herbst, K.L.4    Amory, J.K.5    Anawalt, B.D.6
  • 49
    • 3042683601 scopus 로고    scopus 로고
    • Suppression of the high endogenous levels of plasma FSH in infertile men are associated with improved Sertoli cell function as reflected by elevated levels of plasma inhibin B
    • Foresta C., Bettella A., Spolaore D., Merico M., Rossato M., and Ferlin A. Suppression of the high endogenous levels of plasma FSH in infertile men are associated with improved Sertoli cell function as reflected by elevated levels of plasma inhibin B. Hum Reprod 19 (2004) 1431-1437
    • (2004) Hum Reprod , vol.19 , pp. 1431-1437
    • Foresta, C.1    Bettella, A.2    Spolaore, D.3    Merico, M.4    Rossato, M.5    Ferlin, A.6
  • 50
    • 0035974425 scopus 로고    scopus 로고
    • Operation of the follicle-stimulating hormone (FSH)-inhibin B feedback loop in the control of primate spermatogenesis
    • Ramaswamy S., and Plant T.M. Operation of the follicle-stimulating hormone (FSH)-inhibin B feedback loop in the control of primate spermatogenesis. Mol Cell Endocrinol 180 (2001) 93-101
    • (2001) Mol Cell Endocrinol , vol.180 , pp. 93-101
    • Ramaswamy, S.1    Plant, T.M.2
  • 51
    • 0034109598 scopus 로고    scopus 로고
    • Regulation of inhibin production in the human male and its clinical applications
    • Anderson R.A., and Sharpe R.M. Regulation of inhibin production in the human male and its clinical applications. Int J Androl 23 (2000) 136-144
    • (2000) Int J Androl , vol.23 , pp. 136-144
    • Anderson, R.A.1    Sharpe, R.M.2
  • 52
    • 1842376911 scopus 로고    scopus 로고
    • Men homozygous for an inactivating mutation of the follicle-stimulating hormone (FSH) receptor gene present variable suppression of spermatogenesis and fertility
    • Tapanainen J.S., Aittomäki K., Min J., Vaskivuo T., and Huhtaniemi I.T. Men homozygous for an inactivating mutation of the follicle-stimulating hormone (FSH) receptor gene present variable suppression of spermatogenesis and fertility. Nat Genet 15 (1997) 205-206
    • (1997) Nat Genet , vol.15 , pp. 205-206
    • Tapanainen, J.S.1    Aittomäki, K.2    Min, J.3    Vaskivuo, T.4    Huhtaniemi, I.T.5
  • 53
    • 0032508059 scopus 로고    scopus 로고
    • Male hypogonadism because of a mutation in the gene for the beta-subunit of follicle-stimulating hormone
    • Phillip M., Arbelle J.E., Segev Y., and Parvari R. Male hypogonadism because of a mutation in the gene for the beta-subunit of follicle-stimulating hormone. N Engl J Med 338 (1998) 1729-1732
    • (1998) N Engl J Med , vol.338 , pp. 1729-1732
    • Phillip, M.1    Arbelle, J.E.2    Segev, Y.3    Parvari, R.4
  • 54
    • 0033018934 scopus 로고    scopus 로고
    • Mutational analysis of the follicle-stimulating hormone (FSH) receptor in normal and infertile men: identification and characterization of two discrete FSH receptor isoforms
    • Simoni M., Gromoll J., Höppner W., Kamischke A., Krafft T., Stähle D., et al. Mutational analysis of the follicle-stimulating hormone (FSH) receptor in normal and infertile men: identification and characterization of two discrete FSH receptor isoforms. J Clin Endocrinol Metab 84 (1999) 751-755
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 751-755
    • Simoni, M.1    Gromoll, J.2    Höppner, W.3    Kamischke, A.4    Krafft, T.5    Stähle, D.6
  • 55
  • 56
    • 34548758543 scopus 로고    scopus 로고
    • Splicing in disease: disruption of the splicing code and the decoding machinery
    • Wang G.S., and Cooper T.A. Splicing in disease: disruption of the splicing code and the decoding machinery. Nat Rev Genet 8 (2007) 749-761
    • (2007) Nat Rev Genet , vol.8 , pp. 749-761
    • Wang, G.S.1    Cooper, T.A.2
  • 57
    • 30944469849 scopus 로고    scopus 로고
    • Estrogen carcinogenesis in breast cancer
    • Yager J.D., and Davidson N.D. Estrogen carcinogenesis in breast cancer. N Engl J Med 354 (2006) 270-282
    • (2006) N Engl J Med , vol.354 , pp. 270-282
    • Yager, J.D.1    Davidson, N.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.