Comparison of two ventilatory strategies in elderly patients undergoing major abdominal surgery

British Journal of Anaesthesia

Volumn 104, Issue 1, 2010, Pages 16-22

  Weingarten, T N ^a   Whalen, F X ^a   Warner, D O ^a   Gajic, O ^a   Schears, G J ^a   Snyder, M R ^a   Schroeder, D R ^b   Sprung, J ^a  

^a MAYO CLINIC   (United States)

^b Mayo Clinic   (United States)

Author keywords

Aged; Anaesthesia, general; Positive pressure respiration; Surgery; Ventilation, mechanical

Indexed keywords

INTERLEUKIN 6; INTERLEUKIN 8;

ABDOMINAL SURGERY; AGED; AGING; AIRWAY RESISTANCE; ARTERIAL OXYGEN TENSION; ARTICLE; ASSISTED VENTILATION; BREATHING MECHANICS; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; INFLAMMATION; INTRAOPERATIVE PERIOD; LUNG COMPLIANCE; LUNG HEMODYNAMICS; LUNG MECHANICS; LUNG VENTILATION; MAJOR SURGERY; MALE; OXYGENATION; POSITIVE END EXPIRATORY PRESSURE; POSTOPERATIVE COMPLICATION; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; TIDAL VOLUME;

EID: 72749092243     PISSN: 00070912     EISSN: 14716771     Source Type: Journal    
DOI: 10.1093/bja/aep319     Document Type: Article

References (26)

1. Gunnarsson L, Tokics L, Gustavsson H, Hedenstierna G. Influence of age on atelectasis formation and gas exchange impairment during general anaesthesia. Br J Anaesth 1991; 66: 423-432
2. Edmark L, Kostova-Aherdan K, Enlund M, Hedenstierna G. Optimal oxygen concentration during induction of general anesthesia. Anesthesiology 2003; 98: 28-33 (Pubitemid 36043405)
3. Tusman G, Bohm SH, Vazquez de Anda GF, do Campo JL, Lachmann B. 'Alveolar recruitment strategy' improves arterial oxygenation during general anaesthesia. Br J Anaesth 1999; 82: 8-13
4. Sprung J, Whalen FX, Comfere T, et al. Alveolar recruitment and arterial desflurane concentration during bariatric surgery. Anesth Analg 2009; 108: 120-127
5. Whalen FX, Gajic O, Thompson GB, et al. The effects of the alveolar recruitment maneuver and positive end-expiratory pressure on arterial oxygenation during laparoscopic bariatric surgery. Anesth Analg 2006; 102: 298-305
6. Amato MB, Barbas CS, Medeiros DM, et al. Effect of a protectiveventilation strategy on mortality in the acute respiratory distress syndrome. N Engl J Med 1998; 338: 347-354
7. Tremblay LN, Slutsky AS. Ventilator-induced injury: from barotrauma to biotrauma. Proc Assoc Am Phys 1998; 110: 482-488
8. Marini JJ. Relative importance of stretch and shear in ventilatorinduced lung injury. Crit Care Med 2004; 32: 302-304
9. Tremblay L, Valenza F, Ribeiro SP, Li J, Slutsky AS. Injurious ventilatory strategies increase cytokines and c-fos m-RNA expression in an isolated rat lung model. J Clin Invest 1997; 99: 944-952
10. Sprung J, Gajic O, Warner DO. Review article: age related alterations in respiratory function-anesthetic considerations [Article de synthese: Les modifications de fonction respiratoire liees a l'age-considerations anesthesiques]. Can J Anaesth 2006; 53: 1244-1257
11. Lachmann B. Open up the lung and keep the lung open. Intensive Care Med 1992; 18: 319-321
12. Duggan M, McCaul CL, McNamara PJ, Engelberts D, Ackerley C, Kavanagh BP. Atelectasis causes vascular leak and lethal right ventricular failure in uninjured rat lungs. Am J Respir Crit Care Med 2003; 167: 1633-1640
13. Hartog A, Vazquez de Anda GF, Gommers D, Kaisers U, Lachmann B. At surfactant deficiency, application of 'the open lung concept' prevents protein leakage and attenuates changes in lung mechanics. Crit Care Med 2000; 28: 1450-1454
14. Minkovich L, Djaiani G, Katznelson R, et al. Effects of alveolar recruitment on arterial oxygenation in patients after cardiac surgery: a prospective, randomized, controlled clinical trial. J Cardiothorac Vasc Anesth 2007; 21: 375-378
15. Michelet P, D'Journo XB, Roch A, et al. Protective ventilation influences systemic inflammation after esophagectomy: a randomized controlled study. Anesthesiology 2006; 105: 911-919
16. Choi G, Wolthuis EK, Bresser P, et al. Mechanical ventilation with lower tidal volumes and positive end-expiratory pressure prevents alveolar coagulation in patients without lung injury. Anesthesiology 2006; 105: 689-695
17. Wrigge H, Uhlig U, Baumgarten G, et al. Mechanical ventilation strategies and inflammatory responses to cardiac surgery: a prospective randomized clinical trial. Intensive Care Med 2005; 31: 1379-1387
18. Wrigge H, Zinserling J, Stuber F, et al. Effects of mechanical ventilation on release of cytokines into systemic circulation in patients with normal pulmonary function. Anesthesiology 2000; 93: 1413-1417
19. Talmor D, Sarge T, Legedza A, et al. Cytokine release following recruitment manoeuvres. Chest 2007; 132: 1434-1439
20. Janssens JP, Pache JC, Nicod LP. Physiological changes in respiratory function associated with ageing. Eur Respir J 1999; 13: 197-205
21. Greif R, Akca O, Horn EP, Kurz A, Sessler DI. Supplemental perioperative oxygen to reduce the incidence of surgical-wound infection. Outcomes Research Group. N Engl J Med 2000; 342: 161-167 (Pubitemid 30051647)
22. Allen DB, Maguire JJ, Mahdavian M, et al. Wound hypoxia and acidosis limit neutrophil bacterial killing mechanisms. Arch Surg 1997; 132: 991-996
23. Greif R, Laciny S, Rapf B, Hickle RS, Sessler DI. Supplemental oxygen reduces the incidence of postoperative nausea and vomiting. Anesthesiology 1999; 91: 1246-1252
24. Fleischmann E, Herbst F, Kugener A, et al. Mild hypercapnia increases subcutaneous and colonic oxygen tension in patients given 80% inspired oxygen during abdominal surgery. Anesthesiology 2006; 104: 944-949
25. Hovorka J. Carbon dioxide homeostasis and recovery after general anaesthesia. Acta Anaesthesiol Scand 1982; 26: 498-504
26. Wolthuis EK, Choi G, Dessing MC, et al. Mechanical ventilation with lower tidal volumes and positive end-expiratory pressure prevents pulmonary inflammation in patients without preexisting lung injury. Anesthesiology 2008; 108: 46-54