Endothelial dysfunction in insulin-resistant rats is associated with oxidative stress and COX pathway dysregulation

Physiological Research

Volumn 58, Issue 4, 2009, Pages 499-509

  Oudot, A ^a   Behr Roussel, D ^a   Compagnie, S ^a   Caisey, S ^a   Le Coz, O ^a   Gorny, D ^a   Alexandre, L ^a   Giuliano, F ^a  

^a RAYMOND POINCARÉ HOSPITAL   (France)

Author keywords

Cyclo oxygenase; Endothelial dysfunction; Insulin resistance; Oxidative stress

Indexed keywords

INSULIN; NORADRENALIN; PROSTAGLANDIN SYNTHASE; VASOCONSTRICTOR AGENT;

ANIMAL; ARTICLE; INSULIN RESISTANCE; MALE; METABOLISM; OXIDATIVE STRESS; PHYSIOLOGY; RAT; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIUM; WISTAR RAT;

ANIMALS; ENDOTHELIUM, VASCULAR; INSULIN; INSULIN RESISTANCE; MALE; NOREPINEPHRINE; OXIDATIVE STRESS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION; VASOCONSTRICTOR AGENTS;

EID: 72549113792     PISSN: 08628408     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (52)

1. Anderson TJ, Uehata A, Gerhard MD, Meredith IT, Knab S, Delagrange D, Lieberman EH, Ganz P, Creager MA, Yeung AC Close relation of endothelial function in the human coronary and peripheral circulations. J Am Coll Cardiol 26: 1235-1241, 1995.
2. Bachschmid M, Schildknecht S, Ullrich V : Redox regulation of vascular prostanoid synthesis by the nitric oxide-superoxide system. Biochem Biophys Res Commun 338: 536-542, 2005.
3. Bakker SJ, Ijzerman RG, Teerlink T, Westerhoff HV, Gans RO, Heine RJ : Cytosolic triglycerides and oxidative stress in central obesity: the missing link between excessive atherosclerosis, endothelial dysfunction, and beta-cell failure? Atherosclerosis 148: 17-21, 2000
4. Baron AD : Vascular reactivity. Am J Cardiol 84: 25J-27J, 1999.
5. Baron AD, Clark MG : Role of blood flow in the regulation of muscle glucose uptake. Annu Rev Nutr 17: 487-499, 1997.
6. Bartus M, Lomnicka M, Lorkowska B, Franczyk M, Kostogrys RB, Pisulewski PM, Chlopicki S : Hypertriglyceridemia but not hypercholesterolemia induces endothelial dysfunction in the rat. Pharmacol Rep 57 (Suppl): 127-137, 2005.
7. Behr-Roussel D, Rupin A, Simonet S, Fabiani J, Verbeuren TJ : Urinary nitrate excretion in cholesterolfed rabbits: effect of a chronic treatment by N-iminoethyl-L-lysine, a selective inhibitor of inducible nitric oxide synthase. Eur J Pharmacol 388: 275-279, 2000.
8. Behr-Roussel D, Chamiot-Clerc P, Bernabe J, Mevel K, Alexandre L, Safar ME, Giuliano F : Erectile dysfunction in spontaneously hypertensive rats: pathophysiological mechanisms. Am J Physiol 284: R682-R688, 2003.
9. Bray GA, Nielsen SJ, Popkin BM : Consumption of high-fructose corn syrup in beverages may play a role in the epidemic of obesity. Am J Clin Nutr 79: 537-543, 2004.
10. Carantoni M, Abbasi F, Warmerdam F, Klebanov M, Wang PW, Chen YD, Azhar S, Reaven GM : Relationship between insulin resistance and partially oxidized LDL particles in healthy, nondiabetic volunteers. Arterioscler Thromb Vasc Biol 18: 762-767, 1998.
11. Catena C, Giacchetti G, Novello M, Colussi G, Cavarape A, Sechi LA : Cellular mechanisms of insulin resistance in rats with fructose-induced hypertension. Am J Hypertens 16: 973-978, 2003.
12. Cosentino F, Eto M, De Paolis P, Van Der Loo B, Bachschmid M, Ullrich V, Kouroedov A, Delli Gatti C, Joch H, Volpe M, Lüscher TF : High glucose causes upregulation of cyclooxygenase-2 and alters prostanoid profile in human endothelial cells: role of protein kinase C and reactive oxygen species. Circulation 107: 1017-1023, 2003.
13. D'angelo G, Elmarakby AA, Pollock DM, Stepp DW : Fructose feeding increases insulin resistance but not blood pressure in Sprague-Dawley rats. Hypertension 46: 806-811, 2005.
14. Davidge ST : Prostaglandin H synthase and vascular function. Circ Res 89: 650-660, 2001.
15. Dedon PC, Tannenbaum SR : Reactive nitrogen species in the chemical biology of inflammation. Archives of Biochemistry and Biophysics 423: 12-22, 2004.
16. Delbosc S, Paizanis E, Magous R, Araiz C, Dimo T, Cristol JP, Cros G, Azay J : Involvement of oxidative stress and NADPH oxidase activation in the development of cardiovascular complications in a model of insulin resistance, the fructose-fed rat. Atherosclerosis 179: 43-49, 2005.
17. Elliott SS, Keim NL, Stern JS, Teff K, Havel PJ : Fructose, weight gain, and the insulin resistance syndrome. Am J Clin Nutr 76: 911-922, 2002.
18. Esper RJ, Nordaby RA, Vilarino JO, Paragano A, Cacharron JL, Machado RA : Endothelial dysfunction: a comprehensive appraisal. Cardiovasc Diabetol 5: 4, 2006.
19. Galipeau D, Arikawa E, Sekirov I, Mcneill JH : Chronic thromboxane synthase inhibition prevents fructose-induced hypertension. Hypertension 38: 872-876, 2001.
20. Gopaul NK, Manraj MD, Hebe A, Lee Kwai YS, Johnston A, Carrier MJ, Anggard EE : Oxidative stress could precede endothelial dysfunction and insulin resistance in Indian Mauritians with impaired glucose metabolism. Diabetologia 44: 706-712, 2001.
21. Griendling KK, Alexander RW : Oxidative stress and cardiovascular disease. Circulation 96: 3264-3265, 1997.
22. Grundy SM : Metabolic syndrome: connecting and reconciling cardiovascular and diabetes worlds. J Am Coll Cardiol 47: 1093-1100, 2006.
23. Haffner SM : Epidemiological studies on the effects of hyperglycemia and improvement of glycemic control on macrovascular events in type 2 diabetes. Diabetes Care 22 (Suppl 3): C54-C56, 1999.
24. Jaffe M : Über den Niederschlag, welchen Pikrinsäure in normalen Harn erzeugt und über eine neue Reaction des Kreatininis. Z Phys Chem 10: 391-400, 1886.
25. Kamide K, Rakugi H, Higaki J, Okamura A, Nagai M, Moriguchi K, Ohishi M, Satoh N, Tuck ML, Ogihara T : The renin-angiotensin and adrenergic nervous system in cardiac hypertrophy in fructosefed rats. Am J Hypertens 15: 66-71, 2002.
26. Kanner J, Harel S, Granit R : Nitric oxide, an inhibitor of lipid oxidation by lipoxygenase, cyclooxygenase and hemoglobin. Lipids 27: 46-49, 1992.
27. Katakam PV, Ujhelyi MR, Hoenig ME, Miller AW : Endothelial dysfunction precedes hypertension in dietinduced insulin resistance. Am J Physiol 275: R788-R792, 1998.
28. Kim JA, Montagnani M, Koh KK, Quon MJ : Reciprocal relationships between insulin resistance and endothelial dysfunction: molecular and pathophysiological mechanisms. Circulation 113: 1888-1904, 2006.
29. Koga T, Takata Y, Kobayashi K, Takishita S, Yamashita Y, Fujishima M Age and hypertension promote endothelium-dependent contractions to acetylcholine in the aorta of the rat. Hypertension 14: 542-548, 1989.
30. Lee YC, Ko YH, Hsu YP, Ho LT : Plasma leptin response to oral glucose tolerance and fasting/re-feeding tests in rats with fructose-induced metabolic derangements. Life Sci 78: 1155-1162, 2006.
31. Lüscher TF, Vanhoutte PM : Endothelium-dependent contractions to acetylcholine in the aorta of the spontaneously hypertensive rat. Hypertension 8: 344-348, 1986.
32. Matsuda M, Defronzo RA Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp. Diabetes Care 22: 1462-1470, 1999.
33. Meredith IT, Anderson TJ, Uehata A, Yeung AC, Selwyn AP, Ganz P : Role of endothelium in ischemic coronary syndromes. Am J Cardiol 72: 27C-31C, 1993.
34. Miatello R, Risler N, Gonzalez S, Castro C, Ruttler M, Cruzado M Effects of enalapril on the vascular wall in an experimental model of syndrome X. Am J Hypertens 15: 872-878, 2002.
35. Miatello R, Vazquez M, Renna N, Cruzado M, Zumino AP, Risler N Chronic administration of resveratrol prevents biochemical cardiovascular changes in fructose-fed rats. Am J Hypertens 18: 864-870, 2005.
36. Montuschi P, Barnes PJ, Roberts LJ Isoprostanes: markers and mediators of oxidative stress. FASEB J 18: 1791-1800, 2004.
37. Nagai Y, Nishio Y, Nakamura T, Maegawa H, Kikkawa R, Kashiwagi A Amelioration of high fructose-induced metabolic derangements by activation of PPARalpha. Am J Physiol 282: E1180-E1190, 2002.
38. Nakagawa T, Hu H, Zharikov S, Tuttle KR, Short RA, Glushakova O, Ouyang X, Feig DI, Block ER, Herrera-Acosta J, Patel JM, Johnson RJ A causal role for uric acid in fructoseinduced metabolic syndrome. Am J Physiol 290: F625-F631, 2006.
39. Nyby MD, Matsumoto K, Yamamoto K, Abedi K, Eslami P, Hernandez G, Smutko V, Berger ME, Tuck ML Dietary fish oil prevents vascular dysfunction and oxidative stress in hyperinsulinemic rats. Am J Hypertens 18: 213-219, 2005.
40. Paulis L, Zicha J, Kuneš J, Hojná S, Behuliak M, Celec P, Kojšová S, Pecháňová O, Šimko F Regression of L-NAME-induced hypertension: the role of nitric oxide and endothelium-derived constricting factor. Hypertens Res 31: 793-803, 2008.
41. Pelaez LI, Manriquez MC, Nath KA, Romero JC, Juncos LA Low-dose angiotensin II enhances pressor responses without causing sustained hypertension. Hypertension 42: 798-801, 2003.
42. Reed MJ, Ho H, Donnelly R, Reaven GM Salt-sensitive and carbohydrate-sensitive rodent hypertension: evidence of strain differences. Blood Press 3: 197-201, 1994.
43. Ruiz FJ, Salom MG, Ingles AC, Quesada T, vicente E, Carbonell LF N-acetyl-L-cysteine potentiates depressor response to captopril and enalaprilat in SHRs. Am J Physiol 267: R767-R772, 1994.
44. Sanchez-Lozada LG, Tapia E, Jimenez A, Bautista P, Cristobal M, Nepomuceno T, Soto V, Avila-Casado C, Nakagawa T, Johnson RJ, Herrera-Acosta J, Franco M : Fructoseinduced metabolic syndrome is associated with glomerular hypertension and renal microvascular damage in rats. Am J Physiol 292: F423-F429, 2007.
45. Shinozaki K, Suzuki M, Ikebuchi M, Takaki H, Hara Y, Tsushima M, Harano Y Insulin resistance associated with compensatory hyperinsulinemia as an independent risk factor for vasospastic angina. Circulation 92: 1749-1757, 1995.
46. 2 - imbalance in insulin-resistant rat aorta. Diabetes 48: 2437-2445, 1999.
47. Shinozaki K, Nishio Y, Okamura T, Yoshida Y, Maegawa H, Kojima H, Masada M, Toda N, Kikkawa R, Kashiwagi A Oral administration of tetrahydrobiopterin prevents endothelial dysfunction and vascular oxidative stress in the aortas of insulin-resistant rats. Circ Res 87: 566-573, 2000.
48. Song D, Arikawa E, Galipeau D, Battell M, Mcneill JH Androgens are necessary for the development of fructose-induced hypertension. Hypertension 43: 667-672, 2004.
49. Sonnenberg GE, Krakower GR, Kissebah AH A novel pathway to the manifestations of metabolic syndrome. Obes Res 12: 180-186, 2004.
50. Takada M, Ura N, Higashiura K, Murakami H, Togashi N, Shimamoto K Effects of cilnidipine on muscle fiber composition, capillary density and muscle blood flow in fructose-fed rats. Hypertens Res 24: 565-572, 2001.
51. Takagawa Y, Berger ME, Tuck ML, Golub MS Impaired endothelial alpha-2 adrenergic receptor-mediated vascular relaxation in the fructose-fed rat. Hypertens Res 25: 197-202, 2002.
52. Vasudevan H, Xiang H, Mcneill JH Differential regulation of insulin resistance and hypertension by sex hormones in fructose-fed male rats. Am J Physiol 289: H1335-H1342, 2005.