Anti-thrombin therapy during warm ischemia and cold preservation prevents chronic kidney graft fibrosis in a DCD model

American Journal of Transplantation

Volumn 10, Issue 1, 2010, Pages 30-39

  Favreau, F ^a,b,c   Thuillier, R ^a,b,c   Cau, J ^a,b   Milin, S ^a,b   Manguy, E ^a,b   Mauco, G ^a,b,c   Zhu, X ^d   Lerman, L O ^d   Hauet, T ^a,b,c,e  

^a INSERM   (France)

^b UNIVERSITÉ DE POITIERS   (France)

^c POITIERS UNIVERSITY HOSPITAL   (France)

^d MAYO CLINIC   (United States)

^e CEMAGREF   (France)

Author keywords

Direct thrombin inhibitor; Graft function; Interstitial fibrosis tubular atrophy; Ischemia reperfusion injury; Kidney preservation

Indexed keywords

CALVASCULIN; CONNECTIVE TISSUE GROWTH FACTOR; INDUCIBLE NITRIC OXIDE SYNTHASE; MELAGATRAN; PLASMINOGEN ACTIVATOR INHIBITOR 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; SMAD3 PROTEIN; SMAD4 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNIVERSITY OF WISCONSIN SOLUTION; VIMENTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CRYOPRESERVATION; DISEASE MODEL; DOWN REGULATION; DRUG EFFECT; DRUG EFFICACY; FIBRINOLYSIS; GENE EXPRESSION; GRAFT SURVIVAL; HEART DEATH; HISTOPATHOLOGY; KIDNEY DONOR; KIDNEY DYSFUNCTION; KIDNEY FIBROSIS; KIDNEY ISCHEMIA; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REPERFUSION INJURY; SWINE; TREATMENT OUTCOME;

ADENOSINE; ALLOPURINOL; ANIMALS; ANTICOAGULANTS; AZETIDINES; BASE SEQUENCE; BENZYLAMINES; CHRONIC DISEASE; DNA PRIMERS; FIBROSIS; GLUTATHIONE; HUMANS; INSULIN; KIDNEY; KIDNEY TRANSPLANTATION; MALE; MODELS, ANIMAL; ORGAN PRESERVATION; ORGAN PRESERVATION SOLUTIONS; OXIDATIVE STRESS; PLASMINOGEN ACTIVATOR INHIBITOR 1; RAFFINOSE; RNA, MESSENGER; SIGNAL TRANSDUCTION; SWINE; TEMPERATURE; TISSUE DONORS; TISSUE PLASMINOGEN ACTIVATOR; TRANSFORMING GROWTH FACTOR BETA; TRANSPLANTATION, AUTOLOGOUS;

EID: 72549112632     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/j.1600-6143.2009.02924.x     Document Type: Article

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