메뉴 건너뛰기




Volumn 9, Issue 12, 2009, Pages 2697-2706

CD154 deficiency uncouples allograft CD8+ T-cell effector function from proliferation and inhibits murine airway obliteration

Author keywords

Allograft rejection; CD8 T lymphocyte; Lung transplantation; T cell priming

Indexed keywords

CD40 LIGAND; CD69 ANTIGEN; DIPEPTIDYL PEPTIDASE IV; GAMMA INTERFERON; GRANZYME B; HERMES ANTIGEN; TUMOR NECROSIS FACTOR ALPHA;

EID: 72449190101     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/j.1600-6143.2009.02805.x     Document Type: Article
Times cited : (11)

References (51)
  • 1
    • 34547575004 scopus 로고    scopus 로고
    • Registry of the international society for heart and lung transplantation: Introduction to the 2007 annual reports-100 000 transplants and going strong
    • Hertz MI, Aurora P, Boucek MM et al. Registry of the International Society for Heart and Lung Transplantation: Introduction to the 2007 annual reports-100 000 transplants and going strong. J Heart Lung Transplant 2007 26 : 763 768.
    • (2007) J Heart Lung Transplant , vol.26 , pp. 763-768
    • Hertz, M.I.1    Aurora, P.2    Boucek, M.M.3
  • 3
    • 26944438660 scopus 로고    scopus 로고
    • Lung transplantation: Opportunities for research and clinical advancement
    • Wilkes DS, Egan TM, Reynolds HY. Lung transplantation: Opportunities for research and clinical advancement. Am J Respir Crit Care Med 2005 172 : 944 955.
    • (2005) Am J Respir Crit Care Med , vol.172 , pp. 944-955
    • Wilkes, D.S.1    Egan, T.M.2    Reynolds, H.Y.3
  • 4
    • 0346366973 scopus 로고    scopus 로고
    • Trachea allograft class i molecules directly activate and retain CD8+ T cells that cause obliterative airways disease
    • Richards DM, Dalheimer SL, Hertz MI, Mueller DL. Trachea allograft class I molecules directly activate and retain CD8+ T cells that cause obliterative airways disease. J Immunol 2003 171 : 6919 6928.
    • (2003) J Immunol , vol.171 , pp. 6919-6928
    • Richards, D.M.1    Dalheimer, S.L.2    Hertz, M.I.3    Mueller, D.L.4
  • 5
    • 33846063451 scopus 로고    scopus 로고
    • Human and murine obliterative bronchiolitis in transplant
    • McDyer JF. Human and murine obliterative bronchiolitis in transplant. Proc Am Thorac Soc 2007 4 : 37 43.
    • (2007) Proc Am Thorac Soc , vol.4 , pp. 37-43
    • McDyer, J.F.1
  • 6
    • 0027731124 scopus 로고
    • Reproduction of the obliterative bronchiolitis lesion after heterotopic transplantation of mouse airways
    • Hertz MI, Jessurun J, King MB, Savik SK, Murray JJ. Reproduction of the obliterative bronchiolitis lesion after heterotopic transplantation of mouse airways. Am J Pathol 1993 142 : 1945 1951.
    • (1993) Am J Pathol , vol.142 , pp. 1945-1951
    • Hertz, M.I.1    Jessurun, J.2    King, M.B.3    Savik, S.K.4    Murray, J.J.5
  • 7
    • 13544259006 scopus 로고    scopus 로고
    • Induction of obliterative airway disease in murine tracheal allografts by CD8+ CTLs recognizing a single minor histocompatibility antigen
    • Higuchi T, Maruyama T, Jaramillo A, Mohanakumar T. Induction of obliterative airway disease in murine tracheal allografts by CD8+ CTLs recognizing a single minor histocompatibility antigen. J Immunol 2005 174 : 1871 1878.
    • (2005) J Immunol , vol.174 , pp. 1871-1878
    • Higuchi, T.1    Maruyama, T.2    Jaramillo, A.3    Mohanakumar, T.4
  • 8
    • 0037106496 scopus 로고    scopus 로고
    • Different kinetics of obliterative airway disease development in heterotopic murine tracheal allografts induced by CD4+ and CD8+ T cells
    • Higuchi T, Jaramillo A, Kaleem Z, Patterson GA, Mohanakumar T. Different kinetics of obliterative airway disease development in heterotopic murine tracheal allografts induced by CD4+ and CD8+ T cells. Transplantation 2002 74 : 646 651.
    • (2002) Transplantation , vol.74 , pp. 646-651
    • Higuchi, T.1    Jaramillo, A.2    Kaleem, Z.3    Patterson, G.A.4    Mohanakumar, T.5
  • 9
    • 0032572975 scopus 로고    scopus 로고
    • T-cell and major histocompatibility complex requirements for obliterative airway disease in heterotopically transplanted murine tracheas
    • Kelly KE, Hertz MI, Mueller DL. T-cell and major histocompatibility complex requirements for obliterative airway disease in heterotopically transplanted murine tracheas. Transplantation 1998 66 : 764 771.
    • (1998) Transplantation , vol.66 , pp. 764-771
    • Kelly, K.E.1    Hertz, M.I.2    Mueller, D.L.3
  • 10
    • 29944435583 scopus 로고    scopus 로고
    • Pluripotent allospecific CD8+ effector T cells traffic to lung in murine obliterative airway disease
    • West EE, Lavoie TL, Orens JB et al. Pluripotent allospecific CD8+ effector T cells traffic to lung in murine obliterative airway disease. Am J Respir Cell Mol Biol 2006 34 : 108 118.
    • (2006) Am J Respir Cell Mol Biol , vol.34 , pp. 108-118
    • West, E.E.1    Lavoie, T.L.2    Orens, J.B.3
  • 11
    • 0035890821 scopus 로고    scopus 로고
    • Treatment with the humanized CD154-specific monoclonal antibody, hu5C8, prevents acute rejection of primary skin allografts in nonhuman primates
    • Elster EA, Xu H, Tadaki DK et al. Treatment with the humanized CD154-specific monoclonal antibody, hu5C8, prevents acute rejection of primary skin allografts in nonhuman primates. Transplantation 2001 72 : 1473 1478.
    • (2001) Transplantation , vol.72 , pp. 1473-1478
    • Elster, E.A.1    Xu, H.2    Tadaki, D.K.3
  • 12
    • 0030474264 scopus 로고    scopus 로고
    • Costimulatory function and expression of CD40 ligand, CD80, and CD86 in vascularized murine cardiac allograft rejection
    • Hancock WW, Sayegh MH, Zheng XG, Peach R, Linsley PS, Turka LA. Costimulatory function and expression of CD40 ligand, CD80, and CD86 in vascularized murine cardiac allograft rejection. Proc Natl Acad Sci U S A 1996 93 : 13967 13972.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 13967-13972
    • Hancock, W.W.1    Sayegh, M.H.2    Zheng, X.G.3    Peach, R.4    Linsley, P.S.5    Turka, L.A.6
  • 13
    • 0030860995 scopus 로고    scopus 로고
    • Prolonged survival of mouse skin allografts in recipients treated with donor splenocytes and antibody to CD40 ligand
    • Markees TG, Phillips NE, Noelle RJ et al. Prolonged survival of mouse skin allografts in recipients treated with donor splenocytes and antibody to CD40 ligand. Transplantation 1997 64 : 329 335.
    • (1997) Transplantation , vol.64 , pp. 329-335
    • Markees, T.G.1    Phillips, N.E.2    Noelle, R.J.3
  • 14
    • 0035960617 scopus 로고    scopus 로고
    • Dependence of murine obstructive airway disease on CD40 ligand
    • Rumbley CA, Silver SJ, Phillips SM. Dependence of murine obstructive airway disease on CD40 ligand. Transplantation 2001 72 : 1616 1625.
    • (2001) Transplantation , vol.72 , pp. 1616-1625
    • Rumbley, C.A.1    Silver, S.J.2    Phillips, S.M.3
  • 15
    • 30844436377 scopus 로고    scopus 로고
    • Combined donor specific transfusion and anti-CD154 therapy achieves airway allograft tolerance
    • Chalermskulrat W, McKinnon KP, Brickey WJ et al. Combined donor specific transfusion and anti-CD154 therapy achieves airway allograft tolerance. Thorax 2006 61 : 61 67.
    • (2006) Thorax , vol.61 , pp. 61-67
    • Chalermskulrat, W.1    McKinnon, K.P.2    Brickey, W.J.3
  • 16
    • 21544440627 scopus 로고    scopus 로고
    • Inhibition of obliterative airway disease development following heterotopic murine tracheal transplantation by costimulatory molecule blockade using anti-CD40 ligand alone or in combination with donor bone marrow
    • Fernandez FG, McKane B, Marshbank S, Patterson GA, Mohanakumar T. Inhibition of obliterative airway disease development following heterotopic murine tracheal transplantation by costimulatory molecule blockade using anti-CD40 ligand alone or in combination with donor bone marrow. J Heart Lung Transplant 2005 24 (7 Suppl S232 S238.
    • (2005) J Heart Lung Transplant , vol.24 , Issue.SUPPL.
    • Fernandez, F.G.1    McKane, B.2    Marshbank, S.3    Patterson, G.A.4    Mohanakumar, T.5
  • 17
    • 0028806723 scopus 로고
    • Impairment of antigen-specific T-cell priming in mice lacking CD40 ligand
    • Grewal IS, Xu J, Flavell RA. Impairment of antigen-specific T-cell priming in mice lacking CD40 ligand. Nature 1995 378 : 617 620.
    • (1995) Nature , vol.378 , pp. 617-620
    • Grewal, I.S.1    Xu, J.2    Flavell, R.A.3
  • 18
    • 0032519939 scopus 로고    scopus 로고
    • CD40 ligand/CD40 stimulation regulates the production of IFN-gamma from human peripheral blood mononuclear cells in an IL-12- and/or CD28-dependent manner
    • McDyer JF, Goletz TJ, Thomas E, June CH, Seder RA. CD40 ligand/CD40 stimulation regulates the production of IFN-gamma from human peripheral blood mononuclear cells in an IL-12- and/or CD28-dependent manner. J Immunol 1998 160 : 1701 1707.
    • (1998) J Immunol , vol.160 , pp. 1701-1707
    • McDyer, J.F.1    Goletz, T.J.2    Thomas, E.3    June, C.H.4    Seder, R.A.5
  • 19
    • 0029812593 scopus 로고    scopus 로고
    • Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation
    • Cella M, Scheidegger D, Palmer-Lehmann K, Lane P, Lanzavecchia A, Alber G. Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation. J Exp Med 1996 184 : 747 752.
    • (1996) J Exp Med , vol.184 , pp. 747-752
    • Cella, M.1    Scheidegger, D.2    Palmer-Lehmann, K.3    Lane, P.4    Lanzavecchia, A.5    Alber, G.6
  • 20
    • 0034720744 scopus 로고    scopus 로고
    • CD8+ T cells contribute to the development of transplant arteriosclerosis despite CD154 blockade
    • Ensminger SM, Witzke O, Spriewald BM et al. CD8+ T cells contribute to the development of transplant arteriosclerosis despite CD154 blockade. Transplantation 2000 69 : 2609 2612.
    • (2000) Transplantation , vol.69 , pp. 2609-2612
    • Ensminger, S.M.1    Witzke, O.2    Spriewald, B.M.3
  • 21
    • 0035872724 scopus 로고    scopus 로고
    • CD8 T cell-mediated rejection of intestinal allografts is resistant to inhibition of the CD40/CD154 costimulatory pathway
    • Guo Z, Meng L, Kim O et al. CD8 T cell-mediated rejection of intestinal allografts is resistant to inhibition of the CD40/CD154 costimulatory pathway. Transplantation 2001 71 : 1351 1354.
    • (2001) Transplantation , vol.71 , pp. 1351-1354
    • Guo, Z.1    Meng, L.2    Kim, O.3
  • 22
    • 0034662277 scopus 로고    scopus 로고
    • CD40-CD40 ligand-independent activation of CD8+ T cells can trigger allograft rejection
    • Jones ND, Van Maurik A, Hara M et al. CD40-CD40 ligand-independent activation of CD8+ T cells can trigger allograft rejection. J Immunol 2000 165 : 1111 1118.
    • (2000) J Immunol , vol.165 , pp. 1111-1118
    • Jones, N.D.1    Van Maurik, A.2    Hara, M.3
  • 23
    • 44449122879 scopus 로고    scopus 로고
    • Alloreactive (CD4-Independent) CD8+ T cells jeopardize long-term survival of intrahepatic islet allografts
    • Lunsford KE, Jayanshankar K, Eiring AM et al. Alloreactive (CD4-Independent) CD8+ T cells jeopardize long-term survival of intrahepatic islet allografts. Am J Transplant 2008 8 : 1113 1128.
    • (2008) Am J Transplant , vol.8 , pp. 1113-1128
    • Lunsford, K.E.1    Jayanshankar, K.2    Eiring, A.M.3
  • 24
    • 0033379266 scopus 로고    scopus 로고
    • Asialo GM1(+) CD8(+) T cells play a critical role in costimulation blockade-resistant allograft rejection
    • Trambley J, Bingaman AW, Lin A et al. Asialo GM1(+) CD8(+) T cells play a critical role in costimulation blockade-resistant allograft rejection. J Clin Invest 1999 104 : 1715 1722.
    • (1999) J Clin Invest , vol.104 , pp. 1715-1722
    • Trambley, J.1    Bingaman, A.W.2    Lin, A.3
  • 25
    • 26044443747 scopus 로고    scopus 로고
    • Early regulation of CD8 T cell alloreactivity by CD4+CD25- T cells in recipients of anti-CD154 antibody and allogeneic BMT is followed by rapid peripheral deletion of donor-reactive CD8+ T cells, precluding a role for sustained regulation
    • Fehr T, Takeuchi Y, Kurtz J, Wekerle T, Sykes M. Early regulation of CD8 T cell alloreactivity by CD4+CD25- T cells in recipients of anti-CD154 antibody and allogeneic BMT is followed by rapid peripheral deletion of donor-reactive CD8+ T cells, precluding a role for sustained regulation. Eur J Immunol 2005 35 : 2679 2690.
    • (2005) Eur J Immunol , vol.35 , pp. 2679-2690
    • Fehr, T.1    Takeuchi, Y.2    Kurtz, J.3    Wekerle, T.4    Sykes, M.5
  • 26
    • 0036681543 scopus 로고    scopus 로고
    • The CD154-CD40 T cell costimulation pathway is required for host sensitization of CD8(+) T cells by skin grafts via direct antigen presentation
    • Zhai Y, Shen XD, Gao F et al. The CD154-CD40 T cell costimulation pathway is required for host sensitization of CD8(+) T cells by skin grafts via direct antigen presentation. J Immunol 2002 169 : 1270 1276.
    • (2002) J Immunol , vol.169 , pp. 1270-1276
    • Zhai, Y.1    Shen, X.D.2    Gao, F.3
  • 27
    • 49049110350 scopus 로고    scopus 로고
    • Critical role of CD4 help in CD154 blockade-resistant memory CD8 T cell activation and allograft rejection in sensitized recipients
    • Wu Z, Wang Y, Gao F, Shen X, Zhai Y, Kupiec-Weglinski JW. Critical role of CD4 help in CD154 blockade-resistant memory CD8 T cell activation and allograft rejection in sensitized recipients. J Immunol 2008 181 : 1096 1102.
    • (2008) J Immunol , vol.181 , pp. 1096-1102
    • Wu, Z.1    Wang, Y.2    Gao, F.3    Shen, X.4    Zhai, Y.5    Kupiec-Weglinski, J.W.6
  • 28
    • 0033980596 scopus 로고    scopus 로고
    • Treatment of allograft recipients with donor-specific transfusion and anti-CD154 antibody leads to deletion of alloreactive CD8+ T cells and prolonged graft survival in a CTLA4-dependent manner
    • Iwakoshi NN, Mordes JP, Markees TG, Phillips NE, Rossini AA, Greiner DL. Treatment of allograft recipients with donor-specific transfusion and anti-CD154 antibody leads to deletion of alloreactive CD8+ T cells and prolonged graft survival in a CTLA4-dependent manner. J Immunol 2000 164 : 512 521.
    • (2000) J Immunol , vol.164 , pp. 512-521
    • Iwakoshi, N.N.1    Mordes, J.P.2    Markees, T.G.3    Phillips, N.E.4    Rossini, A.A.5    Greiner, D.L.6
  • 29
    • 52649129667 scopus 로고    scopus 로고
    • Peripheral deletional tolerance of alloreactive CD8 but not CD4 T cells is dependent on the PD-1/PD-L1 pathway
    • Haspot F, Fehr T, Gibbons C et al. Peripheral deletional tolerance of alloreactive CD8 but not CD4 T cells is dependent on the PD-1/PD-L1 pathway. Blood 2008 112 : 2149 2155.
    • (2008) Blood , vol.112 , pp. 2149-2155
    • Haspot, F.1    Fehr, T.2    Gibbons, C.3
  • 30
    • 0032996025 scopus 로고    scopus 로고
    • Treatment with humanized monoclonal antibody against CD154 prevents acute renal allograft rejection in nonhuman primates
    • Kirk AD, Burkly LC, Batty DS et al. Treatment with humanized monoclonal antibody against CD154 prevents acute renal allograft rejection in nonhuman primates. Nat Med 1999 5 : 686 693.
    • (1999) Nat Med , vol.5 , pp. 686-693
    • Kirk, A.D.1    Burkly, L.C.2    Batty, D.S.3
  • 31
    • 0242660129 scopus 로고    scopus 로고
    • CD154 on the surface of CD4+CD25+ regulatory T cells contributes to skin transplant tolerance
    • Jarvinen LZ, Blazar BR, Adeyi OA, Strom TB, Noelle RJ. CD154 on the surface of CD4+CD25+ regulatory T cells contributes to skin transplant tolerance. Transplantation 2003 76 : 1375 1379.
    • (2003) Transplantation , vol.76 , pp. 1375-1379
    • Jarvinen, L.Z.1    Blazar, B.R.2    Adeyi, O.A.3    Strom, T.B.4    Noelle, R.J.5
  • 32
    • 23244459502 scopus 로고    scopus 로고
    • Analysis of the underlying cellular mechanisms of anti-CD154-induced graft tolerance: The interplay of clonal anergy and immune regulation
    • Quezada SA, Bennett K, Blazar BR, Rudensky AY, Sakaguchi S, Noelle RJ. Analysis of the underlying cellular mechanisms of anti-CD154-induced graft tolerance: The interplay of clonal anergy and immune regulation. J Immunol 2005 175 : 771 779.
    • (2005) J Immunol , vol.175 , pp. 771-779
    • Quezada, S.A.1    Bennett, K.2    Blazar, B.R.3    Rudensky, A.Y.4    Sakaguchi, S.5    Noelle, R.J.6
  • 33
    • 4544263376 scopus 로고    scopus 로고
    • Regulation of skin and islet allograft survival in mice treated with costimulation blockade is mediated by different CD4+ cell subsets and different mechanisms
    • Banuelos SJ, Markees TG, Phillips NE et al. Regulation of skin and islet allograft survival in mice treated with costimulation blockade is mediated by different CD4+ cell subsets and different mechanisms. Transplantation 2004 78 : 660 667.
    • (2004) Transplantation , vol.78 , pp. 660-667
    • Banuelos, S.J.1    Markees, T.G.2    Phillips, N.E.3
  • 34
    • 0037111521 scopus 로고    scopus 로고
    • Cutting edge: CD4+CD25+ alloantigen-specific immunoregulatory cells that can prevent CD8+ T cell-mediated graft rejection: Implications for anti-CD154 immunotherapy
    • van Maurik A, Herber M, Wood KJ, Jones ND. Cutting edge: CD4+CD25+ alloantigen-specific immunoregulatory cells that can prevent CD8+ T cell-mediated graft rejection: Implications for anti-CD154 immunotherapy. J Immunol 2002 169 : 5401 5404.
    • (2002) J Immunol , vol.169 , pp. 5401-5404
    • Van Maurik, A.1    Herber, M.2    Wood, K.J.3    Jones, N.D.4
  • 35
    • 0029586280 scopus 로고
    • Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies
    • Prussin C, Metcalfe DD. Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies. J Immunol Methods 1995 188 : 117 128.
    • (1995) J Immunol Methods , vol.188 , pp. 117-128
    • Prussin, C.1    Metcalfe, D.D.2
  • 36
    • 34347232370 scopus 로고    scopus 로고
    • Intracellular cytokine optimization and standard operating procedure
    • Lamoreaux L, Roederer M, Koup R. Intracellular cytokine optimization and standard operating procedure. Nat Protoc 2006 1 : 1507 1516.
    • (2006) Nat Protoc , vol.1 , pp. 1507-1516
    • Lamoreaux, L.1    Roederer, M.2    Koup, R.3
  • 37
    • 17944364488 scopus 로고    scopus 로고
    • Critical role for the chemokine MCP-1/CCR2 in the pathogenesis of bronchiolitis obliterans syndrome
    • Belperio JA, Keane MP, Burdick MD et al. Critical role for the chemokine MCP-1/CCR2 in the pathogenesis of bronchiolitis obliterans syndrome. J Clin Invest 2001 108 : 547 556.
    • (2001) J Clin Invest , vol.108 , pp. 547-556
    • Belperio, J.A.1    Keane, M.P.2    Burdick, M.D.3
  • 38
    • 0036217977 scopus 로고    scopus 로고
    • Lymphocyte-mediated cytotoxicity
    • Russell JH, Ley TJ. Lymphocyte-mediated cytotoxicity. Annu Rev Immunol 2002 20 : 323 370.
    • (2002) Annu Rev Immunol , vol.20 , pp. 323-370
    • Russell, J.H.1    Ley, T.J.2
  • 39
    • 18944367801 scopus 로고    scopus 로고
    • CD4 T cell-dependent conditioning of dendritic cells to produce IL-12 results in CD8-mediated graft rejection and avoidance of tolerance
    • Filatenkov AA, Jacovetty EL, Fischer UB, Curtsinger JM, Mescher MF, Ingulli E. CD4 T cell-dependent conditioning of dendritic cells to produce IL-12 results in CD8-mediated graft rejection and avoidance of tolerance. J Immunol 2005 174 : 6909 6917.
    • (2005) J Immunol , vol.174 , pp. 6909-6917
    • Filatenkov, A.A.1    Jacovetty, E.L.2    Fischer, U.B.3    Curtsinger, J.M.4    Mescher, M.F.5    Ingulli, E.6
  • 40
    • 33846248643 scopus 로고    scopus 로고
    • Rapid quantification of naive alloreactive T cells by TNF-alpha production and correlation with allograft rejection in mice
    • Brehm MA, Mangada J, Markees TG et al. Rapid quantification of naive alloreactive T cells by TNF-alpha production and correlation with allograft rejection in mice. Blood 2007 109 : 819 826.
    • (2007) Blood , vol.109 , pp. 819-826
    • Brehm, M.A.1    Mangada, J.2    Markees, T.G.3
  • 41
    • 0033375952 scopus 로고    scopus 로고
    • CD154 (CD40L) induces human endothelial cell chemokine production and migration of leukocyte subsets
    • Thienel U, Loike J, Yellin MJ. CD154 (CD40L) induces human endothelial cell chemokine production and migration of leukocyte subsets. Cell Immunol 1999 198 : 87 95.
    • (1999) Cell Immunol , vol.198 , pp. 87-95
    • Thienel, U.1    Loike, J.2    Yellin, M.J.3
  • 42
    • 35348876080 scopus 로고    scopus 로고
    • CD40-CD40 ligand interactions promote trafficking of CD8+ T cells into the brain and protection against West Nile virus encephalitis
    • Sitati E, McCandless EE, Klein RS, Diamond MS. CD40-CD40 ligand interactions promote trafficking of CD8+ T cells into the brain and protection against West Nile virus encephalitis. J Virol 2007 81 : 9801 9811.
    • (2007) J Virol , vol.81 , pp. 9801-9811
    • Sitati, E.1    McCandless, E.E.2    Klein, R.S.3    Diamond, M.S.4
  • 43
    • 0346100583 scopus 로고    scopus 로고
    • CD40-mediated immune-nonimmune cell interactions induce mucosal fibroblast chemokines leading to T-cell transmigration
    • Vogel JD, West GA, Danese S et al. CD40-mediated immune-nonimmune cell interactions induce mucosal fibroblast chemokines leading to T-cell transmigration. Gastroenterology 2004 126 : 63 80.
    • (2004) Gastroenterology , vol.126 , pp. 63-80
    • Vogel, J.D.1    West, G.A.2    Danese, S.3
  • 44
    • 0037443493 scopus 로고    scopus 로고
    • Activation of alloreactive CD8+ T cells operates via CD4-dependent and CD4-independent mechanisms and is CD154 blockade sensitive
    • Zhai Y, Meng L, Busuttil RW, Sayegh MH, Kupiec-Weglinski JW. Activation of alloreactive CD8+ T cells operates via CD4-dependent and CD4-independent mechanisms and is CD154 blockade sensitive. J Immunol 2003 170 : 3024 3028.
    • (2003) J Immunol , vol.170 , pp. 3024-3028
    • Zhai, Y.1    Meng, L.2    Busuttil, R.W.3    Sayegh, M.H.4    Kupiec-Weglinski, J.W.5
  • 45
    • 0037108492 scopus 로고    scopus 로고
    • Allograft rejection by primed/memory CD8+ T cells is CD154 blockade resistant: Therapeutic implications for sensitized transplant recipients
    • Zhai Y, Meng L, Gao F, Busuttil RW, Kupiec-Weglinski JW. Allograft rejection by primed/memory CD8+ T cells is CD154 blockade resistant: Therapeutic implications for sensitized transplant recipients. J Immunol 2002 169 : 4667 4673.
    • (2002) J Immunol , vol.169 , pp. 4667-4673
    • Zhai, Y.1    Meng, L.2    Gao, F.3    Busuttil, R.W.4    Kupiec-Weglinski, J.W.5
  • 46
    • 0037544148 scopus 로고    scopus 로고
    • Signal 3 determines tolerance versus full activation of naive CD8 T cells: Dissociating proliferation and development of effector function
    • Curtsinger JM, Lins DC, Mescher MF. Signal 3 determines tolerance versus full activation of naive CD8 T cells: Dissociating proliferation and development of effector function. J Exp Med 2003 197 : 1141 1151.
    • (2003) J Exp Med , vol.197 , pp. 1141-1151
    • Curtsinger, J.M.1    Lins, D.C.2    Mescher, M.F.3
  • 47
    • 0037102167 scopus 로고    scopus 로고
    • Bronchiolitis obliterans after human lung transplantation
    • Estenne M, Hertz MI. Bronchiolitis obliterans after human lung transplantation. Am J Respir Crit Care Med 2002 166 : 440 444.
    • (2002) Am J Respir Crit Care Med , vol.166 , pp. 440-444
    • Estenne, M.1    Hertz, M.I.2
  • 48
    • 0031759684 scopus 로고    scopus 로고
    • Instillation of allogeneic lung macrophages and dendritic cells cause differential effects on local IFN-gamma production, lymphocytic bronchitis, and vasculitis in recipient murine lungs
    • Wilkes DS, Thompson LK, Cummings OW, Bragg S, Heidler KM. Instillation of allogeneic lung macrophages and dendritic cells cause differential effects on local IFN-gamma production, lymphocytic bronchitis, and vasculitis in recipient murine lungs. J Leukoc Biol 1998 64 : 578 586.
    • (1998) J Leukoc Biol , vol.64 , pp. 578-586
    • Wilkes, D.S.1    Thompson, L.K.2    Cummings, O.W.3    Bragg, S.4    Heidler, K.M.5
  • 49
    • 33847152240 scopus 로고    scopus 로고
    • Antigen-specific precursor frequency impacts T cell proliferation, differentiation, and requirement for costimulation
    • Ford ML, Koehn BH, Wagener ME et al. Antigen-specific precursor frequency impacts T cell proliferation, differentiation, and requirement for costimulation. J Exp Med 2007 204 : 299 309.
    • (2007) J Exp Med , vol.204 , pp. 299-309
    • Ford, M.L.1    Koehn, B.H.2    Wagener, M.E.3
  • 50
    • 0035865216 scopus 로고    scopus 로고
    • Differential susceptibility of heart, skin, and islet allografts to T cell-mediated rejection
    • Jones ND, Turvey SE, Van Maurik A et al. Differential susceptibility of heart, skin, and islet allografts to T cell-mediated rejection. J Immunol 2001 166 : 2824 2830.
    • (2001) J Immunol , vol.166 , pp. 2824-2830
    • Jones, N.D.1    Turvey, S.E.2    Van Maurik, A.3
  • 51
    • 34248201743 scopus 로고    scopus 로고
    • Techniques for experimental heterotopic and orthotopic tracheal transplantations - When to use which model?
    • Deuse T, Schrepfer S, Reichenspurner H et al. Techniques for experimental heterotopic and orthotopic tracheal transplantations - When to use which model? Transpl Immunol 2007 17 : 255 261.
    • (2007) Transpl Immunol , vol.17 , pp. 255-261
    • Deuse, T.1    Schrepfer, S.2    Reichenspurner, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.