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Volumn 77, Issue 12, 2009, Pages 5281-5290

Spa15 of Shigella flexneri is secreted through the type III secretion system and prevents staurosporine-induced apoptosis

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; CHAPERONE; CONGO RED; HEMAGGLUTININ; MXIE PROTEIN; SPA 15 PROTEIN; STAUROSPORINE; UNCLASSIFIED DRUG;

EID: 72449187042     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00800-09     Document Type: Article
Times cited : (31)

References (47)
  • 1
    • 0032707085 scopus 로고    scopus 로고
    • Increased interleukin-1 (IL-1) and imbalance between IL-1 and IL-1 receptor antagonist during acute inflammation in experimental shigellosis
    • Arondel, J., M. Singer, A. Matsukawa, A. Zychlinsky, and P. J. Sansonetti. 1999. Increased interleukin-1 (IL-1) and imbalance between IL-1 and IL-1 receptor antagonist during acute inflammation in experimental shigellosis. Infect. Immun. 67:6056-6066.
    • (1999) Infect. Immun. , vol.67 , pp. 6056-6066
    • Arondel, J.1    Singer, M.2    Matsukawa, A.3    Zychlinsky, A.4    Sansonetti, P.J.5
  • 3
    • 33846199469 scopus 로고    scopus 로고
    • Shigella chromosomal IpaH proteins are secreted via the type III secretion system and act as effectors
    • Ashida, H., T. Toyotome, T. Nagai, and C. Sasakawa. 2007. Shigella chromosomal IpaH proteins are secreted via the type III secretion system and act as effectors. Mol. Microbiol. 63:680-693.
    • (2007) Mol. Microbiol. , vol.63 , pp. 680-693
    • Ashida, H.1    Toyotome, T.2    Nagai, T.3    Sasakawa, C.4
  • 4
    • 0030793819 scopus 로고    scopus 로고
    • Secretion of Ipa proteins by Shigella flexneri: Inducer molecules and kinetics of activation
    • Bahrani, F. K., P. J. Sansonetti, and C. Parsot. 1997. Secretion of Ipa proteins by Shigella flexneri: inducer molecules and kinetics of activation. Infect. Immun. 65:4005-4010.
    • (1997) Infect. Immun. , vol.65 , pp. 4005-4010
    • Bahrani, F.K.1    Sansonetti, P.J.2    Parsot, C.3
  • 5
    • 0024362336 scopus 로고
    • Identification of icsA, a plasmid locus of Shigella flexneri that governs bacterial intra- And intercellular spread through interaction with F-actin
    • Bernardini, M. L., J. Mounier, H. d'Hauteville, M. Coquis-Rondon, and P. J. Sansonetti. 1989. Identification of icsA, a plasmid locus of Shigella flexneri that governs bacterial intra- and intercellular spread through interaction with F-actin. Proc. Natl. Acad. Sci. USA 86:3867-3871.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 3867-3871
    • Bernardini, M.L.1    Mounier, J.2    D'Hauteville, H.3    Coquis-Rondon, M.4    Sansonetti, P.J.5
  • 6
    • 0033636701 scopus 로고    scopus 로고
    • The virulence plasmid pWR100 and the repertoire of proteins secreted by the type III secretion apparatus of Shigella flexneri
    • Buchrieser, C., P. Glaser, C. Rusniok, H. Nedjari, H. d'Hauteville, F. Kunst, P. Sansonetti, and C. Parsot. 2000. The virulence plasmid pWR100 and the repertoire of proteins secreted by the type III secretion apparatus of Shigella flexneri. Mol. Microbiol. 38:760-771.
    • (2000) Mol. Microbiol. , vol.38 , pp. 760-771
    • Buchrieser, C.1    Glaser, P.2    Rusniok, C.3    Nedjari, H.4    D'Hauteville, H.5    Kunst, F.6    Sansonetti, P.7    Parsot, C.8
  • 7
    • 34248348720 scopus 로고    scopus 로고
    • Shigella flexneri inhibits staurosporine-induced apoptosis in epithelial cells
    • Clark, C. S., and A. T. Maurelli. 2007. Shigella flexneri inhibits staurosporine-induced apoptosis in epithelial cells. Infect. Immun. 75:2531-2539.
    • (2007) Infect. Immun. , vol.75 , pp. 2531-2539
    • Clark, C.S.1    Maurelli, A.T.2
  • 9
    • 45549097533 scopus 로고    scopus 로고
    • IL-6-dependent mucosal protection prevents establishment of a microbial niche for attaching/effacing lesion-forming enteric bacterial pathogens
    • Dann, S. M., M. E. Spehlmann, D. C. Hammond, M. Iimura, K. Hase, L. J. Choi, E. Hanson, and L. Eckmann. 2008. IL-6-dependent mucosal protection prevents establishment of a microbial niche for attaching/effacing lesion-forming enteric bacterial pathogens. J. Immunol. 180:6816-6826.
    • (2008) J. Immunol. , vol.180 , pp. 6816-6826
    • Dann, S.M.1    Spehlmann, M.E.2    Hammond, D.C.3    Iimura, M.4    Hase, K.5    Choi, L.J.6    Hanson, E.7    Eckmann, L.8
  • 10
    • 0034612342 scopus 로고    scopus 로고
    • One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products
    • Datsenko, K. A., and B. L. Wanner. 2000. One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc. Natl. Acad. Sci. USA 97:6640-6645.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 6640-6645
    • Datsenko, K.A.1    Wanner, B.L.2
  • 11
    • 27544471076 scopus 로고    scopus 로고
    • The mitochondrial death squad: Hardened killers or innocent bystanders?
    • Ekert, P. G., and D. L. Vaux. 2005. The mitochondrial death squad: hardened killers or innocent bystanders? Curr. Opin. Cell Biol. 17:626-630.
    • (2005) Curr. Opin. Cell Biol. , vol.17 , pp. 626-630
    • Ekert, P.G.1    Vaux, D.L.2
  • 12
    • 20744444590 scopus 로고    scopus 로고
    • Secretion of cytokines and chemokines by polarized human epithelial cells from the female reproductive tract
    • Fahey, J. V., T. M. Schaefer, J. Y. Channon, and C. R. Wira. 2005. Secretion of cytokines and chemokines by polarized human epithelial cells from the female reproductive tract. Hum. Reprod. 20:1439-1446.
    • (2005) Hum. Reprod. , vol.20 , pp. 1439-1446
    • Fahey, J.V.1    Schaefer, T.M.2    Channon, J.Y.3    Wira, C.R.4
  • 13
    • 0000637531 scopus 로고
    • Experimental Shigella infections: Characteristics of a fatal infection produced in guinea pigs
    • Formal, S. B., G. J. Dammin, E. H. LaBrec, and H. Schneider. 1958. Experimental Shigella infections: characteristics of a fatal infection produced in guinea pigs. J. Bacteriol. 75:604-610.
    • (1958) J. Bacteriol. , vol.75 , pp. 604-610
    • Formal, S.B.1    Dammin, G.J.2    Labrec, E.H.3    Schneider, H.4
  • 14
    • 10344249890 scopus 로고    scopus 로고
    • Process of protein transport by the type III secretion system
    • Ghosh, P. 2004. Process of protein transport by the type III secretion system. Microbiol. Mol. Biol. Rev. 68:771-795.
    • (2004) Microbiol. Mol. Biol. Rev. , vol.68 , pp. 771-795
    • Ghosh, P.1
  • 16
    • 40949156258 scopus 로고    scopus 로고
    • IpgB1 and IpgB2, two homologous effectors secreted via the Mxi-Spa type III secretion apparatus, cooperate to mediate polarized cell invasion and inflammatory potential of Shigella flexenri
    • Hachani, A., L. Biskri, G. Rossi, A. Marty, R. Menard, P. Sansonetti, C. Parsot, G. T. Van Nhieu, M. L. Bernardini, and A. Allaoui. 2008. IpgB1 and IpgB2, two homologous effectors secreted via the Mxi-Spa type III secretion apparatus, cooperate to mediate polarized cell invasion and inflammatory potential of Shigella flexenri. Microbes Infect. 10:260-268.
    • (2008) Microbes Infect. , vol.10 , pp. 260-268
    • Hachani, A.1    Biskri, L.2    Rossi, G.3    Marty, A.4    Menard, R.5    Sansonetti, P.6    Parsot, C.7    Van Nhieu, G.T.8    Bernardini, M.L.9    Allaoui, A.10
  • 17
    • 0020959710 scopus 로고
    • Studies on transformation of Escherichia coli with plasmids
    • Hanahan, D. 1983. Studies on transformation of Escherichia coli with plasmids. J. Mol. Biol. 166:557-580.
    • (1983) J. Mol. Biol. , vol.166 , pp. 557-580
    • Hanahan, D.1
  • 18
    • 0024415286 scopus 로고
    • Identification of Shigella invasion genes by isolation of temperature-regulated inv::lacZ operon fusions
    • Hromockyj, A. E., and A. T. Maurelli. 1989. Identification of Shigella invasion genes by isolation of temperature-regulated inv::lacZ operon fusions. Infect. Immun. 57:2963-2970.
    • (1989) Infect. Immun. , vol.57 , pp. 2963-2970
    • Hromockyj, A.E.1    Maurelli, A.T.2
  • 19
    • 1242306203 scopus 로고    scopus 로고
    • Shigella flexneri infection: Pathogenesis and vaccine development
    • Jennison, A. V., and N. K. Verma. 2004. Shigella flexneri infection: pathogenesis and vaccine development. FEMS Microbiol. Rev. 28:43-58.
    • (2004) FEMS Microbiol. Rev. , vol.28 , pp. 43-58
    • Jennison, A.V.1    Verma, N.K.2
  • 20
    • 3042542185 scopus 로고    scopus 로고
    • Murine oviduct epithelial cell cytokine responses to Chlamydia muridarum infection include interleukin-12-p70 secretion
    • Johnson, R. M. 2004. Murine oviduct epithelial cell cytokine responses to Chlamydia muridarum infection include interleukin-12-p70 secretion. Infect. Immun. 72:3951-3960.
    • (2004) Infect. Immun. , vol.72 , pp. 3951-3960
    • Johnson, R.M.1
  • 21
    • 0028864991 scopus 로고
    • A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion
    • Jung, H. C., L. Eckmann, S. K. Yang, A. Panja, J. Fierer, E. Morzycka- Wroblewska, and M. F. Kagnoff. 1995. A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion. J. Clin. Investig. 95:55-65.
    • (1995) J. Clin. Investig. , vol.95 , pp. 55-65
    • Jung, H.C.1    Eckmann, L.2    Yang, S.K.3    Panja, A.4    Fierer, J.5    Morzycka-Wroblewska, E.6    Kagnoff, M.F.7
  • 22
    • 0036335636 scopus 로고    scopus 로고
    • MxiE regulates intracellular expression of factors secreted by the Shigella flexneri 2a type III secretion system
    • Kane, C. D., R. Schuch, W. A. Day, Jr., and A. T. Maurelli. 2002. MxiE regulates intracellular expression of factors secreted by the Shigella flexneri 2a type III secretion system. J. Bacteriol. 184:4409-4419.
    • (2002) J. Bacteriol. , vol.184 , pp. 4409-4419
    • Kane, C.D.1    Schuch, R.2    Day Jr., W.A.3    Maurelli, A.T.4
  • 24
    • 14644386707 scopus 로고    scopus 로고
    • Analysis of virulence plasmid gene expression defines three classes of effectors in the type III secretion system of Shigella flexneri
    • DOI 10.1099/mic.0.27639-0
    • Le Gall, T., M. Mavris, M. C. Martino, M. L. Bernardini, E. Denamur, and C. Parsot. 2005. Analysis of virulence plasmid gene expression defines three classes of effectors in the type III secretion system of Shigella flexneri. Microbiology 151:951-962. (Pubitemid 40425029)
    • (2005) Microbiology , vol.151 , Issue.3 , pp. 951-962
    • Le Gall, T.1    Mavris, M.2    Martino, M.C.3    Bernardini, M.L.4    Denamur, E.5    Parsot, C.6
  • 25
    • 0034683665 scopus 로고    scopus 로고
    • Sustained polymorphonuclear leukocyte transmigration induces apoptosis in T84 intestinal epithelial cells
    • DOI 10.1083/jcb.150.6.1479
    • Le'Negrate, G., E. Selva, P. Auberger, B. Rossi, and P. Hofman. 2000. Sustained polymorphonuclear leukocyte transmigration induces apoptosis in T84 intestinal epithelial cells. J. Cell Biol. 150:1479-1488. (Pubitemid 30728918)
    • (2000) Journal of Cell Biology , vol.150 , Issue.6 , pp. 1479-1488
    • Le'Negrate, G.1    Selva, E.2    Auberger, P.3    Rossi, B.4    Hofman, P.5
  • 26
    • 33344459126 scopus 로고    scopus 로고
    • A common structural motif in the binding of virulence factors to bacterial secretion chaperones
    • DOI 10.1016/j.molcel.2006.01.026, PII S1097276506000487
    • Lilic, M., M. Vujanac, and C. E. Stebbins. 2006. A common structural motif in the binding of virulence factors to bacterial secretion chaperones. Mol. Cell 21:653-664. (Pubitemid 43290732)
    • (2006) Molecular Cell , vol.21 , Issue.5 , pp. 653-664
    • Lilic, M.1    Vujanac, M.2    Stebbins, C.E.3
  • 27
    • 0021854510 scopus 로고
    • Cloning of plasmid DNA sequences involved in invasion of HeLa cells by Shigella flexneri
    • Maurelli, A. T., B. Baudry, H. d'Hauteville, T. L. Hale, and P. J. Sansonetti. 1985. Cloning of plasmid DNA sequences involved in invasion of HeLa cells by Shigella flexneri. Infect. Immun. 49:164-171.
    • (1985) Infect. Immun. , vol.49 , pp. 164-171
    • Maurelli, A.T.1    Baudry, B.2    D'Hauteville, H.3    Hale, T.L.4    Sansonetti, P.J.5
  • 28
    • 0036951970 scopus 로고    scopus 로고
    • Identification of the cis-acting site involved in activation of promoters regulated by activity of the type III secretion apparatus in shigella flexneri
    • DOI 10.1128/JB.184.24.6751-6759.2002
    • Mavris, M., P. J. Sansonetti, and C. Parsot. 2002. Identification of the cis-acting site involved in activation of promoters regulated by activity of the type III secretion apparatus in Shigella flexneri. J. Bacteriol. 184:6751-6759. (Pubitemid 36356109)
    • (2002) Journal of Bacteriology , vol.184 , Issue.24 , pp. 6751-6759
    • Mavris, M.1    Sansonetti, P.J.2    Parsot, C.3
  • 29
    • 3543017894 scopus 로고    scopus 로고
    • Requirement of the Shigella flexneri virulence plasmid in the ability to induce trafficking of neutrophils across polarized monolayers of the intestinal epithelium
    • McCormick, B. A., A. M. Siber, and A. T. Maurelli. 1998. Requirement of the Shigella flexneri virulence plasmid in the ability to induce trafficking of neutrophils across polarized monolayers of the intestinal epithelium. Infect. Immun. 66:4237-4243.
    • (1998) Infect. Immun. , vol.66 , pp. 4237-4243
    • McCormick, B.A.1    Siber, A.M.2    Maurelli, A.T.3
  • 30
    • 0028113512 scopus 로고
    • Extracellular association and cytoplasmic partitioning of the IpaB and IpaC invasins of S. flexneri
    • DOI 10.1016/0092-8674(94)90260-7
    • Menard, R., P. Sansonetti, C. Parsot, and T. Vasselon. 1994. Extracellular association and cytoplasmic partitioning of the IpaB and IpaC invasins of S. flexneri. Cell 79:515-525. (Pubitemid 24346066)
    • (1994) Cell , vol.79 , Issue.3 , pp. 515-525
    • Menard, R.1    Sansonetti, P.2    Parsot, C.3    Vasselon, T.4
  • 31
    • 0023700084 scopus 로고
    • Shigella flexneri invasion plasmid antigens B and C: Epitope location and characterization with monoclonal antibodies
    • Mills, J. A., J. M. Buysse, and E. V. Oaks. 1988. Shigella flexneri invasion plasmid antigens B and C: epitope location and characterization with monoclonal antibodies. Infect. Immun. 56:2933-2941.
    • (1988) Infect. Immun. , vol.56 , pp. 2933-2941
    • Mills, J.A.1    Buysse, J.M.2    Oaks, E.V.3
  • 32
    • 0021916459 scopus 로고
    • Plaque formation by virulent Shigella flexneri
    • Oaks, E. V., M. E. Wingfield, and S. B. Formal. 1985. Plaque formation by virulent Shigella flexneri. Infect. Immun. 48:124-129.
    • (1985) Infect. Immun. , vol.48 , pp. 124-129
    • Oaks, E.V.1    Wingfield, M.E.2    Formal, S.B.3
  • 33
    • 21244451603 scopus 로고    scopus 로고
    • IpgB1 is a novel Shigella effector protein involved in bacterial invasion of host cells. Its activity to promote membrane ruffling via Rac1 and Cdc42 activation
    • Ohya, K., Y. Handa, M. Ogawa, M. Suzuki, and C. Sasakawa. 2005. IpgB1 is a novel Shigella effector protein involved in bacterial invasion of host cells. Its activity to promote membrane ruffling via Rac1 and Cdc42 activation. J. Biol. Chem. 280:24022-24034.
    • (2005) J. Biol. Chem. , vol.280 , pp. 24022-24034
    • Ohya, K.1    Handa, Y.2    Ogawa, M.3    Suzuki, M.4    Sasakawa, C.5
  • 34
    • 0036267949 scopus 로고    scopus 로고
    • Spa15 of Shigella flexneri, a third type of chaperone in the type III secretion pathway
    • Page, A. L., P. Sansonetti, and C. Parsot. 2002. Spa15 of Shigella flexneri, a third type of chaperone in the type III secretion pathway. Mol. Microbiol. 43:1533-1542.
    • (2002) Mol. Microbiol. , vol.43 , pp. 1533-1542
    • Page, A.L.1    Sansonetti, P.2    Parsot, C.3
  • 35
    • 20344407810 scopus 로고    scopus 로고
    • A secreted anti-activator, OspD1, and its chaperone, Spa15, are involved in the control of transcription by the type III secretion apparatus activity in Shigella flexneri
    • Parsot, C., E. Ageron, C. Penno, M. Mavris, K. Jamoussi, H. d'Hauteville, P. Sansonetti, and B. Demers. 2005. A secreted anti-activator, OspD1, and its chaperone, Spa15, are involved in the control of transcription by the type III secretion apparatus activity in Shigella flexneri. Mol. Microbiol. 56:1627-1635.
    • (2005) Mol. Microbiol. , vol.56 , pp. 1627-1635
    • Parsot, C.1    Ageron, E.2    Penno, C.3    Mavris, M.4    Jamoussi, K.5    D'Hauteville, H.6    Sansonetti, P.7    Demers, B.8
  • 36
    • 40449099126 scopus 로고    scopus 로고
    • The chaperone IpgC copurifies with the virulence regulator MxiE
    • Pilonieta, M. C., and G. P. Munson. 2008. The chaperone IpgC copurifies with the virulence regulator MxiE. J. Bacteriol. 190:2249-2251.
    • (2008) J. Bacteriol. , vol.190 , pp. 2249-2251
    • Pilonieta, M.C.1    Munson, G.P.2
  • 37
    • 0036259826 scopus 로고    scopus 로고
    • Apoptosis in acute shigellosis is associated with increased production of Fas/Fas ligand, perforin, caspase-1, and caspase-3 but reduced production of Bcl-2 and interleukin-2
    • Raqib, R., C. Ekberg, P. Sharkar, P. K. Bardhan, A. Zychlinsky, P. J. Sansonetti, and J. Andersson. 2002. Apoptosis in acute shigellosis is associated with increased production of Fas/Fas ligand, perforin, caspase-1, and caspase-3 but reduced production of Bcl-2 and interleukin-2. Infect. Immun. 70:3199-3207.
    • (2002) Infect. Immun. , vol.70 , pp. 3199-3207
    • Raqib, R.1    Ekberg, C.2    Sharkar, P.3    Bardhan, P.K.4    Zychlinsky, A.5    Sansonetti, P.J.6    Andersson, J.7
  • 38
    • 0029945905 scopus 로고    scopus 로고
    • Infection of rabbit Peyer's patches by Shigella flexneri: Effect of adhesive or invasive bacterial phenotypes on follicle-associated epithelium
    • Sansonetti, P. J., J. Arondel, J. R. Cantey, M.-C. Prévost, and M. Huerre. 1996. Infection of rabbit Peyer's patches by Shigella flexneri: effect of adhesive or invasive bacterial phenotypes on follicle-associated epithelium. Infect. Immun. 64:2752-2764.
    • (1996) Infect. Immun. , vol.64 , pp. 2752-2764
    • Sansonetti, P.J.1    Arondel, J.2    Cantey, J.R.3    Prévost, M.-C.4    Huerre, M.5
  • 39
    • 38549126641 scopus 로고    scopus 로고
    • Molecular pathogenesis of Shigella spp.: Controlling host cell signaling, invasion, and death by type III secretion
    • Schroeder, G. N., and H. Hilbi. 2008. Molecular pathogenesis of Shigella spp.: controlling host cell signaling, invasion, and death by type III secretion. Clin. Microbiol. Rev. 21:134-156.
    • (2008) Clin. Microbiol. Rev. , vol.21 , pp. 134-156
    • Schroeder, G.N.1    Hilbi, H.2
  • 40
    • 0034254475 scopus 로고    scopus 로고
    • Supramolecular structure of the Shigella type III secretion machinery: The needle part is changeable in length and essential for delivery of effectors
    • Tamano, K., S. Aizawa, E. Katayama, T. Nonaka, S. Imajoh-Ohmi, A. Kuwae, S. Nagai, and C. Sasakawa. 2000. Supramolecular structure of the Shigella type III secretion machinery: the needle part is changeable in length and essential for delivery of effectors. EMBO J. 19:3876-3887.
    • (2000) EMBO J. , vol.19 , pp. 3876-3887
    • Tamano, K.1    Aizawa, S.2    Katayama, E.3    Nonaka, T.4    Imajoh-Ohmi, S.5    Kuwae, A.6    Nagai, S.7    Sasakawa, C.8
  • 42
    • 0030994387 scopus 로고    scopus 로고
    • Modulation of bacterial entry into epithelial cells by association between vinculin and the Shigella IpaA invasin
    • Tran Van Nhieu, G., A. Ben-Ze'ev, and P. J. Sansonetti. 1997. Modulation of bacterial entry into epithelial cells by association between vinculin and the Shigella IpaA invasin. EMBO J. 16:2717-2729.
    • (1997) EMBO J. , vol.16 , pp. 2717-2729
    • Van Nhieu, T.1    Ben-Ze'ev, G.A.2    Sansonetti, P.J.3
  • 43
    • 0026522202 scopus 로고
    • Surface presentation of Shigella flexneri invasion plasmid antigens requires the products of the spa locus
    • Venkatesan, M. M., J. M. Buysse, and E. V. Oaks. 1992. Surface presentation of Shigella flexneri invasion plasmid antigens requires the products of the spa locus. J. Bacteriol. 174:1990-2001.
    • (1992) J. Bacteriol. , vol.174 , pp. 1990-2001
    • Venkatesan, M.M.1    Buysse, J.M.2    Oaks, E.V.3
  • 44
    • 0033546440 scopus 로고    scopus 로고
    • Cytokine-induced apoptosis in epithelial HT-29 cells is independent of nitric oxide formation. Evidence for an interleukin-13-driven phosphatidylinositol 3-kinase-dependent survival mechanism
    • Wright, K., G. Kolios, J. Westwick, and S. G. Ward. 1999. Cytokine-induced apoptosis in epithelial HT-29 cells is independent of nitric oxide formation. Evidence for an interleukin-13-driven phosphatidylinositol 3-kinase-dependent survival mechanism. J. Biol. Chem. 274:17193-17201.
    • (1999) J. Biol. Chem. , vol.274 , pp. 17193-17201
    • Wright, K.1    Kolios, G.2    Westwick, J.3    Ward, S.G.4
  • 45
    • 27744547067 scopus 로고    scopus 로고
    • SGLT-1-mediated glucose uptake protects intestinal epithelial cells against LPS-induced apoptosis and barrier defects: A novel cellular rescue mechanism?
    • Yu, L. C., A. N. Flynn, J. R. Turner, and A. G. Buret. 2005. SGLT-1-mediated glucose uptake protects intestinal epithelial cells against LPS-induced apoptosis and barrier defects: a novel cellular rescue mechanism? FASEB J. 19:1822-1835.
    • (2005) FASEB J. , vol.19 , pp. 1822-1835
    • Yu, L.C.1    Flynn, A.N.2    Turner, J.R.3    Buret, A.G.4
  • 46
    • 33749237700 scopus 로고    scopus 로고
    • OspF and OspC1 are Shigella flexneri type III secretion system effectors that are required for postinvasion aspects of virulence
    • Zurawski, D. V., C. Mitsuhata, K. L. Mumy, B. A. McCormick, and A. T. Maurelli. 2006. OspF and OspC1 are Shigella flexneri type III secretion system effectors that are required for postinvasion aspects of virulence. Infect. Immun. 74:5964-5976.
    • (2006) Infect. Immun. , vol.74 , pp. 5964-5976
    • Zurawski, D.V.1    Mitsuhata, C.2    Mumy, K.L.3    McCormick, B.A.4    Maurelli, A.T.5


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