Sodium channel modulators prevent oxygen and glucose deprivation injury and glutamate release in rat neocortical cultures

Neuropharmacology

Volumn 36, Issue 8, 1997, Pages 1031-1038

  Probert, A W ^a   Borosky, S ^a   Marcoux, F W ^a   Taylor, C P ^a  

^a PFIZER INC   (United States)

Author keywords

Ischemia; Lidocaine; Na channel; Phenytoin; Stroke; Tetrodotoxin

Indexed keywords

4 (3 PHOSPHONOPROPYL) 2 PIPERAZINECARBOXYLIC ACID; CALCIUM 45; GLUCOSE; GLUTAMIC ACID; LACTATE DEHYDROGENASE; LIDOCAINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PHENYTOIN; SODIUM CHANNEL; SODIUM CHANNEL BLOCKING AGENT; TETRODOTOXIN;

ANIMAL CELL; ARTICLE; CALCIUM TRANSPORT; CELL CULTURE; CELL DEATH; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME RELEASE; FETUS; HYPOXIA; ISCHEMIA; NEOCORTEX; NERVE CELL LESION; NEUROPROTECTION; NEUROTRANSMITTER RELEASE; NONHUMAN; PREVENTION; PRIORITY JOURNAL; RAT;

ANIMALS; CALCIUM; CELL DEATH; CELL HYPOXIA; CELLS, CULTURED; CEREBRAL CORTEX; EXCITATORY AMINO ACID ANTAGONISTS; GLUCOSE; GLUTAMIC ACID; L-LACTATE DEHYDROGENASE; LIDOCAINE; NEURONS; PHENYTOIN; PIPERAZINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE; SODIUM CHANNEL BLOCKERS; TETRODOTOXIN;

EID: 0030835331     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(97)00072-5     Document Type: Article

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