Specific activation of leukocyte β2 integrins lymphocyte function- associated antigen-1 and Mac-1 by chemokines mediated by distinct pathways via the α subunit cytoplasmic domains

Molecular Biology of the Cell

Volumn 10, Issue 4, 1999, Pages 861-873

  Weber, Kim S C ^a   Klickstein, Lloyd B ^b   Weber, Christian ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; CHEMOKINE; CHEMOKINE RECEPTOR; EPITOPE; INTEGRIN; INTERCELLULAR ADHESION MOLECULE 1; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; MONOCYTE CHEMOTACTIC PROTEIN 1;

ALPHA CHAIN; ARTICLE; CELL ADHESION; CHEMOTAXIS; CHIMERA; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; MONOCYTE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION;

EID: 0032908819     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.10.4.861     Document Type: Article

References (63)

1. Amatruda, T.T., Gerard, N.P., Gerard, C., and Simon, M.L (1993). Specific interactions of chemoattractant factor receptors with G-proteins. J. Biol. Chem. 268, 10139-10144.
2. Baggiolini, M., Dewald, B., and Moser, B. (1994). Interleukin-8 and related chemotactic cytokines - CXC and CC chemokines. Adv. Immunol. 55, 97-179.
3. Baker, E.K., Tozer, E.C., Pfaff, M., Shattil, S.J., Loftus, J.C., and Ginsberg, M.H. (1997). A genetic analysis of integrin function: Glanzmann thrombasthenia in vitro. Proc. Natl. Acad. Sci. USA 94, 1973-1978.
4. Boyum, A. (1983). Isolation of human blood monocytes with Nycodenz, a new nonionic iodinated gradient medium. Scand. J. Immunol. 17, 429-436.
5. Campbell, J.J., Hedrik, J., Zlotnik, A., Siani, M.A., Thompson, D.A., and Butcher, E.C. (1998). Chemokines and the arrest of lymphocytes rolling under flow conditions. Science 279, 381-384.
6. Carr, M.W., Alon, R., and Springer, T.A. (1996). The C-C chemokine MCP-1 differentially modulates the avidity of β1 and β2 integrins on T lymphocytes. Immunity 4, 179-182.
7. Carr, M.W., Roth, S.J., Luther, E., Rose, S.S., and Springer, T.A. (1994). Monocyte chemoattractant protein-1 is a major T lymphocyte chemoattractant. Proc. Natl. Acad. Sci. USA 91, 3652-3656.
8. Chan, B.M.C., Kassner, P.D., Schiro, J.A., Byers, H.R., Kupper, T.S., and Hemler, M.E. (1992). Distinct cellular functions mediated by different VLA integrin α subunit cytoplasmic domains. Cell 68, 1051-1060.
9. Chang, D., Wong, C., Smith, H., and Liu, J. (1997). ICAP-1, a novel β1 integrin cytoplasmic domain-associated protein, binds to a conserved and functionally important NPXY sequence motif of β1 integrin. J. Cell Biol. 138, 1149-1157.
10. Dedhar, S., and Hannigan G.E. (1996). Integrin cytoplasmic interactions and bidirectional transmembrane signaling. Curr. Opin. Cell Biol. 8, 657-669.
11. de Fougerolles, A.R., Stacker, S.A., Schwarting, R., and Springer, T.A. (1991). Characterization of ICAM-2 and evidence for a third counterreceptor for LFA-1. J. Exp. Med. 174, 253-267.
12. Detmers, P.A., Lo, S.K., Olsen-Egbert, E., Walz, A., Baggiolini, M., and Cohn, Z.A. (1990). Neutrophil-activating protein 1/interleukin 8 stimulates the binding activity of the leukocyte adhesion receptor CD11b/CD18 on human neutrophils. J. Exp. Med. 171, 1155-1162.
13. Diamond, M.S., and Springer, T.A. (1993). A subpopulation of Mac-1 (CD11b/CD18) molecules mediates neutrophil adhesion to ICAM-1 and fibrinogen. J. Cell Biol. 120, 545-556.
14. Diamond, M.S., and Springer, T.A. (1994). The dynamic regulation of integrin adhesiveness. Curr. Biol. 4, 506-517.
15. Dransfield, I., Cabañas, C., Craig, A., and Hogg, N. (1992). Divalent cation regulation of the function of the leukocyte integrin LFA-1. J. Cell Biol. 116, 219-226.
16. Dustin, M.L., and Springer, T.A. (1989). T cell receptor cross-linking transiently stimulates adhesiveness through LFA-1. Nature 341, 619-624.
17. Hato, T., Pampori, N., and Shattil, S.J. (1998). Complementary roles for receptor clustering and conformational changes in the adhesive and signaling functions of the integrin αIIbβ3. J. Cell Biol. 141, 1685-1695.
18. Hesselgesser, J., Liang, M., Hoxie, J., Greenberg, M., Brass, L.F., Orsini, M.J., Taub, D., and Horuk, R. (1998). Identification and characterization of the CXCR4 chemokine receptor in human T cell lines: ligand binding, biological activity and HIV-1 infectivity. J. Immunol. 160, 877-883.
19. Hollander, N., Selvaraj, P., and Springer T.A. (1988). Biosynthesis and function of LFA-3 in human mutant cells deficient in phosphotidylinositol-anchored proteins. J. Immunol. 141, 4283-4290.
20. Hwang, S.T., Singer, M.S., Giblin, P.A., Yednock, T.A., Bacon, K.B., Simon, S.I., and Rosen, S.D. (1996). GlyCAM-1, a physiologic ligand for L-selectin, activates β2 integrins on naive peripheral lymphocytes. J. Exp. Med. 184, 1343-1348.
21. Hynes, R.O. (1992). Integrins: versatility, modulation and signaling in cell adhesion. Cell 69, 11-25.
22. Issekutz, T.B. (1995). In vivo blood monocyte migration to acute inflammatory reactions, IL-1α, TNF-α, IFN-γ, and C5a utilizes LFA-1, Mac-1, and VLA-4: the relative importance of each integrin. J. Immunol. 154, 6533-6540.
23. Jones, S.L., Knaus, U.G., Bokoch, G.M., and Brown, E.J. (1998). Two signaling mechanisms for activation of αMβ2 avidity in polymorphonuclear neutrophils. J. Biol. Chem. 273, 19556-19666.
24. Kashiwagi, H., Schwartz, M.A., Eigenthaler, M., Davis, K.A., Ginsberg, M.H., and Shattil, S.J. (1997). Affinity modulation of platelet integrin aIIbβ3 by β3-endonexin, a selective binding partner of the β3 integrin cytoplasmic tail. J. Cell Biol. 137, 1433-1443.
25. Kassner, P.D., Alon, R., Springer, T.A., and Hemler, M.E. (1995). Specialized functional roles for the integrin α4 cytoplasmic domain. Mol. Biol. Cell 6, 661-674.
26. Kavanaugh, A.F., Lightfoot, E., Lipsky, P.E., and Oppenheimer-Marks, N. (1991). Role of CD11/CD18 in adhesion and transendothelial migration of T cells: analysis utilizing CD18-deficient T cell clones. J. Immunol. 146, 4149-4156.
27. Kolanus, W., Nagel, W., Schiller, B., Zeitlmann, L., Godar, S., Stockinger, H., and Seed, B. (1996). αLβ2 integrin by cytohesin-1, a cytoplasmic regulatory molecule. Cell 86, 233-242.
28. Kucik, D.F., Dustin, M.L., Miller, J.M., and Brown, E.J. (1996). Adhesion-activating phorbol ester increases the mobility of leukocyte integrin LFA-1 in cultured lymphocytes. J. Clin. Invest. 97, 2139-2144,
29. Kunkel, T.A. (1985). Rapid and efficient site-specific mutagenesis without phenotypic selection. Proc. Natl. Acad. Sci. USA. 82, 488-492.
30. Lo, S.K., Detmers, P.A., Levin, S.M., and Wright S.D. (1989). Transient adhesion of neutrophils to endothelium. J. Exp. Med. 169, 1779-1793.
31. Lollo, B.A., Chan, K.W., Hanson, E.M., Moy, V.T., and Brian, A.A. (1993). Direct evidence for two affinity states for lymphocyte function-associated antigen 1 on activated T cells. J. Biol. Chem. 268, 21693-21700.
32. Lu, C.F., and Springer, T.A. (1997). The a subunit cytoplasmic domain regulates the assembly and adhesiveness of integrin lymphocyte function-associated antigen-1 (LFA-1). J. Immunol. 159, 268-278.
33. Lub, M., van Kooyk, Y., van Vliet, S.J., and Figdor, C.G. (1997a). Dual role of the actin cytoskeleton in regulating cell adhesion mediated by the integrin lymphocyte function-associated molecule-1. Mol. Biol. Cell 8, 341-351.
34. Lub, M., van Vliet, S.J., Oomen, S.P.M.A., Pieters, R.A., Robinson, M., Figdor, C.G., and van Kooyk, Y. (1997b). Cytoplasmic tails of β1, β2, and β7 integrins differentially regulate LFA-1 function in K562 cells. Mol. Biol. Cell. 8, 719-728.
35. Marlin, S.D., Staunton, D.E., Springer, T.A., Stratowa, C., Sommergruber, W., and Merluzzi, V. (1990). A soluble form of intercellular adhesion molecule-1 inhibits rhinovirus infection. Nature 344, 70-72.
36. Meerschaert, J., and Furie, M.B. (1995). The adhesion molecules used by monocytes for migration across endothelium include CD11a/ CD18, CD11b/CD18, and VLA-4 on monocytes and ICAM-1, VCAM-1, and other ligands on endothelium. J. Immunol. 154, 4099-4112.
37. Mobley, J.L., Ennis, E., and Shimizu, Y. (1996). Isolation and characterization of cell lines with genetically distinct mutations downstream of protein kinase C that result in defective activation-dependent regulation of T cell integrin function. J. Immunol. 156, 948-956.
38. Naik, U.P., Patel, P.M., and Parise, L.V. (1997). Identification of a novel calcium-binding protein that interacts with the integrin αIIb cytoplasmic domain. J. Biol. Chem. 272, 4651-4654.
39. Newton, R.A., and Hogg, N. (1998). The human S100 protein MRP-14 is a novel activator of the β2 integrin Mac-1 on neutrophils. J. Immunol. 160, 1427-1435.
40. O'Toole, T.E., Katagiri, Y., Faull, R.J., Peter, K., Tamura, R., Quaranta, V., Loftus, J.C., Shattil, S.J., and Ginsberg, M.H. (1994). Integrin cytoplasmic domains mediate inside-out signal transduction. J. Cell Biol. 124, 1047-1059.
41. Petruzzelli, L., Maduzia, L., and Springer, T.A. (1995). Activation of LFA-1 (CD11a/CD18) mimicked by an antibody directed against CD18. J. Immunol. 155, 854-866.
42. Piali, L., Weber, C., LaRosa, G., Mackay, C.R., Springer, T.A., Clark-Lewis, I., and Moser, B. (1998). The chemokines IP10 and Mig induce rapid and shear-resistant adhesion of activated T lymphocytes to endothelial integrin ligands via CXCR3. Eur. J. Immunol. 28, 961-972.
43. Sadhu, C., Masinovsky, B., and Staunton, D.E. (1998). Differential regulation of chemoattractant-stimulated β2, β3, and β7 integrin activity. J. Immunol. 160, 5622-5628.
44. Sanchez-Madrid, F., Krensky, A.M., Ware, C.F., Robbins, E., Strominger, J.L., Burakoff, S.J., and Springer, T.A. (1982). Three distinct antigens associated with human T lymphocyte-mediated cytolysis: LFA-1, LFA-2 and LFA-3. Proc. Natl. Acad. Sci. USA 79, 7489-7493.
45. Shattil, S.J., O'Toole, T., Eigenthaler, M., Thon, V., Williams, M., Babior, B.M., and Ginsberg, M.H. (1995). β3-Endonexin, a novel polypeptide that interacts specifically with the cytoplasmic tail of the integrin β2 subunit. J. Cell Biol. 131, 807-816.
46. Simon, D.I., Rao, N.K., Xu, H., Wie, Y., Majdic, O., Ronne, E., Kobzik, L., and Chapman, H.A. (1996). Mac-1 (CD11b/CD18) and the urokinase receptor (CD87) form a functional unit on monocytic cells Blood. 88, 3185-3194.
47. Sims, P.J., Ginsberg, M.H., Plow, E.F., and Shattil, S.J. (1991). Effect of platelet activation on the conformation of the plasma membrane glycoprotein IIb-IIIa complex. J. Biol. Chem. 266, 7345-7352.
48. Smith, C.W., Marlin, S.D., Rothlein, R., Toman, C., and Anderson, D.C. (1989). Cooperative interactions of LFA-1 and Mac-1 with intercellular adhesion molecule-1 in facilitating adherence and transendothelial migration of human neutrophils in vitro. J. Clin. Invest. 83, 2008-2017.
49. Springer, T.A. (1990). Adhesion receptors of the immune system. Nature 346, 425-433.
50. Stewart, M.P., Cabanas, C., and Hogg, N. (1996). T cell adhesion to intercellular adhesion molecule-1 (ICAM-1) is controlled by cell spreading and the activation of integrin LFA-1. J. Immunol. 156, 1810-1817.
51. 2+-dependent protease, calpain. J. Cell Biol. 140, 699-707.
52. Straus, D.B., and Weiss, A. (1992). Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor. Cell 70, 585-593.
53. Tanaka, Y., Adams, D.A., Hubscher S., Hirano, H., Siebenlist, U., and Shaw, S. (1993). T-cell adhesion induced by proteoglycan-immobilized cytokine MIP-1β. Nature 361, 79-82.
54. van Kooyk, Y., van de Wiel-van Kemande, P., Weder, P., Kuijpers, T.W., and Figdor, C.F. (1989). Enhancement of LFA-1-mediated cell adhesion by triggering through CD2 or CD3 on T lymphocytes. Nature 342, 811-813.
55. Weber, C., Alon, R., and Springer, T.A. (1996a). Sequential regulation of α4β1 and α5β1 integrin avidity by CC chemokines in monocytes: implications for transendothelial chemotaxis. J. Cell Biol. 134, 1063-1073.
56. Weber, C., Kitayama, J., and Springer, T.A. (1996b). Differential regulation of β1 and β2 integrin avidity by chemoattractants in eosinophils. Proc. Natl. Acad. Sci. USA 93, 10939-10944.
57. Weber, C., Lu, C-F., Casasnovas, J., and Springer, T.A. (1997a). Role of the αLβ2 integrin avidity in transendothelial chemotaxis of mononuclear cells. J. Immunol. 159, 3968-3975.
58. Weber, C., and Springer, T.A. (1998). VLA-4 avidity regulation by chemokines facilitates lateral migration of monocytes. J. Immunol. 161, 6825-6834.
59. Weber, K.S.C., von Hundelshausen P., Clark-Lewis, I., Weber, P.C., Weber, C. (1999). Differential chemokine immobilization and hierarchical involvement of their receptors in monocyte arrest and transmigration on inflammatory endothelium. Eur. J. Immunol. 29, 700-712.
60. Weber, K.S.C., York, M.J., Springer, T.A., and Klickstein, L.B. (1997b). Characterization of lymphocyte function-associated antigen 1 (LFA-1)-deficient T cell lines. J. Immunol. 153, 273-279.
61. Xue, W., Kindzelskii, A.L., Todd, R.F., and Petty, H.R. (1994). Physical association of complement receptor type 3 and urokinase-type plasminogen activator receptor in neutrophil membranes. J. Immunol. 152, 4630-4640.
62. Yamada, K.M., and Miyamoto, S. (1995). Integrin transmembrane signaling and cytoskeletal control. Curr. Opin. Cell Biol. 5, 681-689.
63. Yauch, R.L., Felsenfeld, D.P., Kraeft, S.-K., Chen, L.B., Sheetz, M.P., and Hemler M.E. (1997). Mutational evidence for control of cell adhesion through integrin diffusion/clustering, independent of ligand binding. J. Exp. Med. 186, 1347-1355.