Acyl-CoA carboxylases (accD2 and accD3), together with a unique polyketide synthase (Cg-pks), are key to mycolic acid biosynthesis in Corynebacterianeae such as Corynebacterium glutamicum and Mycobacterium tuberculosis

Journal of Biological Chemistry

Volumn 279, Issue 43, 2004, Pages 44847-44857

  Gande, Roland ^a   Gibson, Kevin J C ^c   Brown, Alistair K ^c   Krumbach, Karin ^a   Dover, Lynn G ^c   Sahm, Hermann ^a   Shioyama, Susumu ^b   Oikawa, Tadao ^b   Besra, Gurdyal S ^c   Eggeling, Lothar ^a  

^a FORSCHUNGSZENTRUM JÜLICH   (Germany)

^b KANSAI UNIVERSITY   (Japan)

^c UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; BIOSYNTHESIS; CARBOXYLATION; ESCHERICHIA COLI; FUNGI; GENES; LIPIDS;

CARBOXYLTRANSFERASES; GLUCOSE MYCOLATES; MYCLOLIC ACIDS; POLYKETIDE SYNTHASE;

CARBOXYLIC ACIDS;

ACETYL COENZYME A; ACETYL COENZYME A CARBOXYLASE; CARBOXYLTRANSFERASE; FATTY ACID; MALONYL COENZYME A; MYCOLIC ACID; OLEIC ACID; POLYKETIDE SYNTHASE; TREHALOSE;

ALPHA CHAIN; ARTICLE; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIUM MUTANT; BIOSYNTHESIS; CARBOXYLATION; CELL LYSATE; CELL WALL; CONTROLLED STUDY; CORYNEBACTERIUM GLUTAMICUM; DELETION MUTANT; GENE OVEREXPRESSION; LIPOGENESIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL;

BLOTTING, SOUTHERN; CARBON-CARBON LIGASES; CELL PROLIFERATION; CORYNEBACTERIUM GLUTAMICUM; ESCHERICHIA COLI; FATTY ACIDS; GENE DELETION; GENOME, BACTERIAL; GENOTYPE; LIPID METABOLISM; LIPIDS; MALONYL COENZYME A; MODELS, BIOLOGICAL; MODELS, GENETIC; MUTATION; MYCOBACTERIUM TUBERCULOSIS; MYCOLIC ACIDS; PEPTIDES; PHENOTYPE; PHYLOGENY; PLASMIDS; POLYKETIDE SYNTHASES; POLYMERASE CHAIN REACTION; PROTEIN STRUCTURE, TERTIARY; TIME FACTORS;

ACTINOBACTERIA (CLASS); BACTERIA (MICROORGANISMS); CORYNEBACTERIUM; CORYNEBACTERIUM GLUTAMICUM; ESCHERICHIA COLI; FUNGI; MYCOBACTERIUM; MYCOBACTERIUM LEPRAE; MYCOBACTERIUM TUBERCULOSIS; UNCULTURED ACTINOMYCETE;

EID: 7244242397     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M408648200     Document Type: Article

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