-
1
-
-
0028150954
-
Why do some organisms use a urea-methylamine mixture as osmolyte? Thermodynamic compensation of urea and trimethylamine N-oxide interactions with protein
-
Lin, T. Y., and S. N. Timasheff. 1994. Why do some organisms use a urea-methylamine mixture as osmolyte? Thermodynamic compensation of urea and trimethylamine N-oxide interactions with protein. Biochemistry. 33:12695-12701.
-
(1994)
Biochemistry
, vol.33
, pp. 12695-12701
-
-
Lin, T.Y.1
Timasheff, S.N.2
-
2
-
-
72249110639
-
Trimethylamine oxide counteracts effects of hydrostatic pressure on proteins of deep-sea teleosts
-
Yancey, P. H., W. R. Blake, and J. Conley. 2002. Trimethylamine oxide counteracts effects of hydrostatic pressure on proteins of deep-sea teleosts. Comp. Biochem. Physiol. 131B:675-694.
-
(2002)
Comp. Biochem. Physiol.
, vol.131
, pp. 675-694
-
-
Yancey, P.H.1
Blake, W.R.2
Conley, J.3
-
3
-
-
40849111530
-
Singular efficacy of trimethylamine N-oxide to counter destabilization in ice
-
Strambini, G. B., and M. Gonnelli. 2008. Singular efficacy of trimethylamine N-oxide to counter destabilization in ice. Biochemistry. 47:3322-3331.
-
(2008)
Biochemistry.
, vol.47
, pp. 3322-3331
-
-
Strambini, G.B.1
Gonnelli, M.2
-
4
-
-
15744404427
-
Counteracting osmolyte trimethylamine N-oxide destabilizes proteins at pH below its pK(a)
-
Singh, R., I. Haque, and F. Ahmad. 2005. Counteracting osmolyte trimethylamine N-oxide destabilizes proteins at pH below its pK(a). J. Biol. Chem. 280:11035-11042.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 11035-11042
-
-
Singh, R.1
Haque, I.2
Ahmad, F.3
-
5
-
-
33748069813
-
Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes
-
DOI 10.1126/science.1128294
-
Ozcan, U., E. Yilmaz, L. Ozcan, M. Furuhashi, E. Vaillancourt, et al. 2006. Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes. Science. 313:1137-1140. (Pubitemid 44300242)
-
(2006)
Science
, vol.313
, Issue.5790
, pp. 1137-1140
-
-
Ozcan, U.1
Yilmaz, E.2
Ozcan, L.3
Furuhashi, M.4
Vaillancourt, E.5
Smith, R.O.6
Gorgun, C.Z.7
Hotamisligil, G.S.8
-
6
-
-
0031967834
-
Trimethylamine-N-oxide counteracts urea effects on rabbit muscle lactate dehydrogenase function: A test of the counteraction hypothesis
-
Baskakov, I., A. Wang, and D. W. Bolen. 1998. Trimethylamine-N-oxide counteracts urea effects on rabbit muscle lactate dehydrogenase function: a test of the counteraction hypothesis. Biophys. J. 74:2666-2673. (Pubitemid 28225260)
-
(1998)
Biophysical Journal
, vol.74
, Issue.5
, pp. 2666-2673
-
-
Baskakov, I.1
Wang, A.2
Bolen, D.W.3
-
7
-
-
46449109015
-
Structure and energetics of the hydrogen-bonded backbone in protein folding
-
Bolen, D. W., and G. D. Rose. 2008. Structure and energetics of the hydrogen-bonded backbone in protein folding. Annu. Rev. Biochem. 77:339-362.
-
(2008)
Annu. Rev. Biochem.
, vol.77
, pp. 339-362
-
-
Bolen, D.W.1
Rose, G.D.2
-
8
-
-
4344614677
-
Effects of naturally occuring osmolytes on protein stability and solubility: Issues important in protein crystallization
-
Bolen, D. W. 2004. Effects of naturally occuring osmolytes on protein stability and solubility: issues important in protein crystallization. Methods. 34:312-322.
-
(2004)
Methods
, vol.34
, pp. 312-322
-
-
Bolen, D.W.1
-
9
-
-
0037138672
-
The molecular mechanism of stabilization of proteins by TMAO and its ability to counteract the effects of urea
-
Zou, Q., B. J. Bennion, V. Daggett, and K. P. Murphy. 2002. The molecular mechanism of stabilization of proteins by TMAO and its ability to counteract the effects of urea. J. Am. Chem. Soc. 124:1192-1202.
-
(2002)
J. Am. Chem. Soc.
, vol.124
, pp. 1192-1202
-
-
Zou, Q.1
Bennion, B.J.2
Daggett, V.3
Murphy, K.P.4
-
10
-
-
33845923185
-
The effects of cosolutes on protein dynamics: The reversal of denaturant-induced protein fluctuations by trimethylamine N-oxide
-
DOI 10.1110/ps.062393707
-
Doan-Nguyen, V., and J. P. Loria. 2007. The effects of cosolutes on protein dynamics: the reversal of denaturant-induced protein fluctuations by trimethylamine N-oxide. Protein Sci. 16:20-29. (Pubitemid 46036495)
-
(2007)
Protein Science
, vol.16
, Issue.1
, pp. 20-29
-
-
Doan-Nguyen, V.1
Patrick Loria, J.2
-
11
-
-
33744501033
-
The role of water coordination in binary mixtures. a study of two model amphiphilic molecules in aqueous solutions by molecular dynamics and NMR
-
Sinibaldi, R., C. Casieri, S. Melchionna, G. Onori, A. L. Segre, et al. 2006. The role of water coordination in binary mixtures. A study of two model amphiphilic molecules in aqueous solutions by molecular dynamics and NMR. J. Phys. Chem. B. 110:8885-8892.
-
(2006)
J. Phys. Chem. B
, vol.110
, pp. 8885-8892
-
-
Sinibaldi, R.1
Casieri, C.2
Melchionna, S.3
Onori, G.4
Segre, A.L.5
-
12
-
-
48749129145
-
Thermal signature of hydrophobic hydration dynamics
-
Qvist, J., and B. Halle. 2008. Thermal signature of hydrophobic hydration dynamics. J. Am. Chem. Soc. 130:10346-10353.
-
(2008)
J. Am. Chem. Soc.
, vol.130
, pp. 10346-10353
-
-
Qvist, J.1
Halle, B.2
-
13
-
-
34247121912
-
Structure and interaction in aqueous urea-trimethylamine- N-oxide solutions
-
Paul, S., and G. N. Patey. 2007. Structure and interaction in aqueous urea-trimethylamine- N-oxide solutions. J. Am. Chem. Soc. 129:4476-4482.
-
(2007)
J. Am. Chem. Soc.
, vol.129
, pp. 4476-4482
-
-
Paul, S.1
Patey, G.N.2
-
14
-
-
52349100015
-
Hydrophobic interactions in urea-trimethylamine- N-oxide solutions
-
Paul, S., and G. N. Patey. 2008. Hydrophobic interactions in urea-trimethylamine- N-oxide solutions. J. Phys. Chem. B. 112:11106-11111.
-
(2008)
J. Phys. Chem. B
, vol.112
, pp. 11106-11111
-
-
Paul, S.1
Patey, G.N.2
-
15
-
-
35748930873
-
Simulations of macromolecules in protective and denaturing osmolytes: Properties of mixed solvent systems and their effects on water and protein structure and dynamics
-
Beck, D. A. C., B. J. Bennion, D. O. V. Alonso, and V. Daggett. 2007. Simulations of macromolecules in protective and denaturing osmolytes: properties of mixed solvent systems and their effects on water and protein structure and dynamics. Methods Enzymol. 428:373-396.
-
(2007)
Methods Enzymol.
, vol.428
, pp. 373-396
-
-
Beck, D.A.C.1
Bennion, B.J.2
Alonso, D.O.V.3
Daggett, V.4
-
16
-
-
78650700965
-
-
ISIS Facility, Rutherford Appleton Laboratory, Chilton, UK
-
McLain, S. E., D. T. Bowron, A. C. Hannon, A. K. Soper. GUDRUN, a Computer Program Developed for Analysis of Neutron Diffraction Data. ISIS Facility, Rutherford Appleton Laboratory, Chilton, UK.
-
GUDRUN, a Computer Program Developed for Analysis of Neutron Diffraction Data
-
-
McLain, S.E.1
Bowron, D.T.2
Hannon, A.C.3
Soper, A.K.4
-
17
-
-
36449008796
-
A neutron-diffraction study of dimethyl-sulfoxide water mixtures
-
Soper, A. K., and A. Luzar. 1992. A neutron-diffraction study of dimethyl-sulfoxide water mixtures. J. Phys. Chem. B. 97:1320-1331.
-
(1992)
J. Phys. Chem. B
, vol.97
, pp. 1320-1331
-
-
Soper, A.K.1
Luzar, A.2
-
18
-
-
24944544628
-
Partial structure factors from disorderd materials diffraction data: An approach using empirical potential structure refinement
-
Soper, A. K. 2005. Partial structure factors from disorderd materials diffraction data: an approach using empirical potential structure refinement. Phys. Rev. B. 72:104204.
-
(2005)
Phys. Rev. B.
, vol.72
, pp. 104204
-
-
Soper, A.K.1
-
20
-
-
23244459863
-
Osmolyte trimethylamine- N-oxide does not affect the strength of hydrophobic interactions: Origin of osmolyte compatibility
-
Athawale, M. V., J. S. Dordick, and S. Garde. 2005. Osmolyte trimethylamine- N-oxide does not affect the strength of hydrophobic interactions: origin of osmolyte compatibility. Biophys. J. 89:858-866.
-
(2005)
Biophys. J.
, vol.89
, pp. 858-866
-
-
Athawale, M.V.1
Dordick, J.S.2
Garde, S.3
-
21
-
-
68849117193
-
Inelasticity corrections for time-of-flight and fixed wavelength neutron diffraction experiments
-
Soper, A. K. 2009. Inelasticity corrections for time-of-flight and fixed wavelength neutron diffraction experiments. Mol. Phys. 107:1667-1684.
-
(2009)
Mol. Phys.
, vol.107
, pp. 1667-1684
-
-
Soper, A.K.1
-
22
-
-
4243089023
-
Solvent structure and perturbations in solutions of chemical and biological importance
-
Finney, J. L., and A.K. Soper. 1994. Solvent structure and perturbations in solutions of chemical and biological importance.Chem. Soc. Rev. 23:1-10.
-
(1994)
Chem. Soc. Rev.
, vol.23
, pp. 1-10
-
-
Finney, J.L.1
Soper, A.K.2
-
23
-
-
0141560450
-
Impact of urea on water structure: A clue to its properties as a denaturant?
-
Soper, A. K., E. W. Castner, and A. Luzar. 2003. Impact of urea on water structure: a clue to its properties as a denaturant? Biophys. Chem. 105:649-666.
-
(2003)
Biophys. Chem.
, vol.105
, pp. 649-666
-
-
Soper, A.K.1
Castner, E.W.2
Luzar, A.3
-
24
-
-
0034662899
-
The radial distribution functions of water and ice from 220 to 673 K and at pressures up to 400 MPa
-
Soper, A. K. 2000. The radial distribution functions of water and ice from 220 to 673 K and at pressures up to 400 MPa. Chem. Phys. 258:121-137.
-
(2000)
Chem. Phys.
, vol.258
, pp. 121-137
-
-
Soper, A.K.1
-
25
-
-
0035826443
-
Temperature dependence of the structure of a 0.06 mole fraction tertiary butanol-water solution
-
Bowron, D. T., A. K. Soper, and J. L. Finney. 2001. Temperature dependence of the structure of a 0.06 mole fraction tertiary butanol-water solution. J. Chem. Phys. 114:6203-6219.
-
(2001)
J. Chem. Phys.
, vol.114
, pp. 6203-6219
-
-
Bowron, D.T.1
Soper, A.K.2
Finney, J.L.3
-
26
-
-
0035961057
-
Infrared study of the hydrophobic hydration and hydrophobic interactions in aqueous solutions of tert-butyl alcohol and trimethylamine-n-oxide
-
Freda, M., G. Onori, and A. Santucci. 2001. Infrared study of the hydrophobic hydration and hydrophobic interactions in aqueous solutions of tert-butyl alcohol and trimethylamine-n-oxide. J. Phys. Chem. B. 105:12714-12718.
-
(2001)
J. Phys. Chem. B
, vol.105
, pp. 12714-12718
-
-
Freda, M.1
Onori, G.2
Santucci, A.3
-
27
-
-
0000556942
-
Comparison of the water perturbations induced by two small organic solutes: Ab initio calculations and molecular dynamics simulation
-
Noto, R., V. Martorana, A. Emanuele, and S. L. Fornili. 1995. Comparison of the water perturbations induced by two small organic solutes: ab initio calculations and molecular dynamics simulation. J. Chem. Soc., Faraday Trans. 91:3803-3808.
-
(1995)
J. Chem. Soc., Faraday Trans.
, vol.91
, pp. 3803-3808
-
-
Noto, R.1
Martorana, V.2
Emanuele, A.3
Fornili, S.L.4
-
28
-
-
0001474254
-
Modeling chemoadaptive behavior: X-ray structure of the trimethylamine oxide-urea (1:4) complex
-
Anthoni, U., C. Christophersen, M. Gajhede, and P. H. Nielsen. 1992. Modeling chemoadaptive behavior: X-ray structure of the trimethylamine oxide-urea (1:4) complex. Struct. Chem. 3:121-128.
-
(1992)
Struct. Chem.
, vol.3
, pp. 121-128
-
-
Anthoni, U.1
Christophersen, C.2
Gajhede, M.3
Nielsen, P.H.4
-
29
-
-
65249176368
-
Destabilization of the hydrogen-bond structure of water by the osmolyte trimethylamine N-oxide
-
Rezus, Y. L. A., and H. J. Bakker. 2009. Destabilization of the hydrogen-bond structure of water by the osmolyte trimethylamine N-oxide. J. Phys. Chem. B. 113:4038-4044.
-
(2009)
J. Phys. Chem. B
, vol.113
, pp. 4038-4044
-
-
Rezus, Y.L.A.1
Bakker, H.J.2
-
31
-
-
0036703676
-
Water structure from scattering experiments and simulation
-
Head-Gordon, T., and G. Hura. 2002. Water structure from scattering experiments and simulation. Chem. Rev. 102:2651-2670.
-
(2002)
Chem. Rev.
, vol.102
, pp. 2651-2670
-
-
Head-Gordon, T.1
Hura, G.2
-
32
-
-
0000125216
-
Calibration and testing of a water model for simulation of the molecular dynamics of proteins and nucleic acids in solution
-
Levitt, M., M. Hirshberg, R. Sharon, K. Laidig, and V. Daggett. 1997. Calibration and testing of a water model for simulation of the molecular dynamics of proteins and nucleic acids in solution. J. Phys. Chem. B. 101:5051-5061.
-
(1997)
J. Phys. Chem. B
, vol.101
, pp. 5051-5061
-
-
Levitt, M.1
Hirshberg, M.2
Sharon, R.3
Laidig, K.4
Daggett, V.5
-
33
-
-
33745467540
-
Why tert-butyl alcohol associates in aqueous solution but trimethylamine-N-oxide does not
-
Paul, S., and G. N. Patey. 2006. Why tert-butyl alcohol associates in aqueous solution but trimethylamine-N-oxide does not. J. Phys. Chem. B. 110:10514-10518.
-
(2006)
J. Phys. Chem. B
, vol.110
, pp. 10514-10518
-
-
Paul, S.1
Patey, G.N.2
-
34
-
-
0035800731
-
Osmolytes stabilize ribonuclease S by stabilizing its fragments S protein and S peptide to compact folding-competent states
-
Ratnaparkhi, G. S., and R. Vandarajan. 2001. Osmolytes stabilize ribonuclease S by stabilizing its fragments S protein and S peptide to compact folding-competent states. J. Biol. Chem. 276:28789-28798.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 28789-28798
-
-
Ratnaparkhi, G.S.1
Vandarajan, R.2
-
35
-
-
33646512405
-
On the edge of the denaturation process: Application of X-ray diffraction to barnase and lysozyme cross-linked crystals with denaturants in molar concentrations
-
Salem, M., Y. Mauguen, and T. Prange. 2006. On the edge of the denaturation process: application of X-ray diffraction to barnase and lysozyme cross-linked crystals with denaturants in molar concentrations. Biochim. Biophys. Acta. 1764:903-912.
-
(2006)
Biochim. Biophys. Acta
, vol.1764
, pp. 903-912
-
-
Salem, M.1
Mauguen, Y.2
Prange, T.3
-
36
-
-
0000347724
-
Dielectric relaxation in aqueous solutions of urea and some of its derivatives
-
Kaatze, U., H. Gerke, and R. Pottel. 1986. Dielectric relaxation in aqueous solutions of urea and some of its derivatives. J. Phys. Chem. 90:5464-5469.
-
(1986)
J. Phys. Chem.
, vol.90
, pp. 5464-5469
-
-
Kaatze, U.1
Gerke, H.2
Pottel, R.3
-
37
-
-
0036450690
-
Dielectric relaxation of aqueous trimethylamineoxide solutions
-
DOI 10.1023/A:1021349411687
-
Shikata, T., and S. Itatani. 2002. Dielectric relaxation of aqueous trimethylamineoxide solutions. J. Solution Chem. 31:823-844. (Pubitemid 37115693)
-
(2002)
Journal of Solution Chemistry
, vol.31
, Issue.10
, pp. 823-844
-
-
Shikata, T.1
Itatani, S.2
-
38
-
-
33751296851
-
Modulation of hydrophobic effect by cosolutes
-
Di Michele, A., M. Freda, G. Onori, M. Paolantoni, A. Santucci, et al. 2006. Modulation of hydrophobic effect by cosolutes. J. Phys. Chem. B. 110:21077-21085.
-
(2006)
J. Phys. Chem. B
, vol.110
, pp. 21077-21085
-
-
Di Michele, A.1
Freda, M.2
Onori, G.3
Paolantoni, M.4
Santucci, A.5
-
39
-
-
1242319518
-
Impact of protein denaturants and stabilizers on water structure
-
Batchelor, J. D., A. Olteanu, A. Tripathy, and G. J. Pielak. 2004. Impact of protein denaturants and stabilizers on water structure. J. Am. Chem. Soc. 126:1958-1961.
-
(2004)
J. Am. Chem. Soc.
, vol.126
, pp. 1958-1961
-
-
Batchelor, J.D.1
Olteanu, A.2
Tripathy, A.3
Pielak, G.J.4
-
40
-
-
24644466893
-
Effect of alcohols on protein hydration: Crystallographic analysis of hen egg-white lysozyme in the presence of alcohols
-
Deshpande, A., S. Nimsadkar, and S. C. Mande. 2005. Effect of alcohols on protein hydration: crystallographic analysis of hen egg-white lysozyme in the presence of alcohols. Acta Crystallogr. D Biol. Crystallogr. 61:1005-1008.
-
(2005)
Acta Crystallogr. D Biol. Crystallogr.
, vol.61
, pp. 1005-1008
-
-
Deshpande, A.1
Nimsadkar, S.2
Mande, S.C.3
-
41
-
-
0038311869
-
Protein stability in mixed solvents: A balance of contact interaction and excluded volume
-
Schellman, J. A. 2003. Protein stability in mixed solvents: a balance of contact interaction and excluded volume. Biophys. J. 85:108-125.
-
(2003)
Biophys. J.
, vol.85
, pp. 108-125
-
-
Schellman, J.A.1
-
42
-
-
35748981504
-
Application of the transfer model to understand how naturally occurring osmolytes affect protein stability
-
Auton, M., and D. W. Bolen. 2007. Application of the transfer model to understand how naturally occurring osmolytes affect protein stability. Methods Enzymol. 428:397-418.
-
(2007)
Methods Enzymol.
, vol.428
, pp. 397-418
-
-
Auton, M.1
Bolen, D.W.2
-
43
-
-
2342614722
-
Counteraction of urea-induced protein denaturation by trimethylamine N-oxide: A chemical chaperone at atomic resolution
-
Bennion, B. J., and V. Daggett. 2004. Counteraction of urea-induced protein denaturation by trimethylamine N-oxide: a chemical chaperone at atomic resolution. Proc. Natl. Acad. Sci. USA. 101:6433-6438.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 6433-6438
-
-
Bennion, B.J.1
Daggett, V.2
-
44
-
-
0035949666
-
On the nature of a glassy state of matter in a hydrated protein: Relation to protein function
-
Teeter, M. M., A. Yamano, B. Stec, and U. Mohanty. 2001. On the nature of a glassy state of matter in a hydrated protein: relation to protein function. Proc. Natl. Acad. Sci. USA. 98:11242-11247.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 11242-11247
-
-
Teeter, M.M.1
Yamano, A.2
Stec, B.3
Mohanty, U.4
-
45
-
-
0028220369
-
A structural basis for the interaction of urea with lysozyme
-
Pike, A. C. W., and K. R. Acharya. 1994. A structural basis for the interaction of urea with lysozyme. Protein Sci. 3:706-710.
-
(1994)
Protein Sci.
, vol.3
, pp. 706-710
-
-
Pike, A.C.W.1
Acharya, K.R.2
-
46
-
-
55149098533
-
New insights into urea action on proteins: A SANS study of the lysozyme case
-
Ortore, M. G., R. Sinibaldi, F. Spinozzi, F. Carsughi, D. Clemens, et al. 2008. New insights into urea action on proteins: a SANS study of the lysozyme case. J. Phys. Chem. B. 112:12881-12887.
-
(2008)
J. Phys. Chem. B
, vol.112
, pp. 12881-12887
-
-
Ortore, M.G.1
Sinibaldi, R.2
Spinozzi, F.3
Carsughi, F.4
Clemens, D.5
-
47
-
-
0008025420
-
CI study of the water dimer potential surface
-
Matsuoka, O., E. Clementi, and M. Yoshimine. 1976. CI study of the water dimer potential surface. J. Chem. Phys. 64:1351-1361.
-
(1976)
J. Chem. Phys.
, vol.64
, pp. 1351-1361
-
-
Matsuoka, O.1
Clementi, E.2
Yoshimine, M.3
|