PANDAS: A possible model for adult OCD pathogenesis;Il PANDAS come possibile modello interpretativo del meccanismo patogenetico del DOC nell'adulto

Rivista di Psichiatria

Volumn 44, Issue 5, 2009, Pages 285-298

  Marconi, Daniela ^a   Limpido, Lucilla ^a   Bersani, Iliana ^b   Giordano, Annalisa ^a   Bersani, Giuseppe ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b CATHOLIC UNIVERSITY   (Italy)

Author keywords

Antineuronal antibodies; Autoimmunity; Obsessive compulsive disorder; PANDAS

Indexed keywords

EPITOPE; IMMUNOGLOBULIN; INTERLEUKIN 1; INTERLEUKIN 6; STREPTOCOCCUS ANTIGEN; TUMOR NECROSIS FACTOR ALPHA;

BASAL GANGLION; BLOOD LEVEL; CHOREA MINOR; CROSS REACTION; DISEASE EXACERBATION; ECHOTOMOGRAPHY; GENETIC PREDISPOSITION; GENETIC SUSCEPTIBILITY; HEART VALVE; HUMAN; IMMUNOPATHOGENESIS; NEUROIMAGING; OBSESSIVE COMPULSIVE DISORDER; PLASMAPHERESIS; REVIEW; STREPTOCOCCUS GROUP A; STREPTOCOCCUS INFECTION; TIC;

AUTOIMMUNE DISEASES OF THE NERVOUS SYSTEM; HUMANS; MODELS, PSYCHOLOGICAL; OBSESSIVE-COMPULSIVE DISORDER; STREPTOCOCCAL INFECTIONS;

EID: 72249099690     PISSN: 00356484     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (118)

1. Geller DA, Biederman JS, Jones J, Shapiro S, Schwartz S, Park K: Obsessive-compulsive disorder in children and adolescents: a review. Harvard Review of Psychiatry, 1998, 5, 260-273. (Pubitemid 28092102)
2. Rapoport JL: Obsessive-compulsive disorder and basal ganglia dysfunction. Psychological Medicine, 1990, 20, 465-469.
3. Rapaport JL, Fiske A: The new biology of obsessive-compulsive disorder: implications for evolutionary psychology. Perspectives in Biology and Medicine, 1998, 41, 159-175.
4. Billett EA, Richter MA, Kennedy JL: Genetics of obsessive-compulsive disorder. In: Swinson RP, Antony MM, Rachman S, Richter MA (eds). Obsessive-compulsive disorder theory, research and treatment. Guilford Press, New York, 1998.
5. nd: The inheritance of obsessive-compulsive disorder. Child and Adolescent Psychiatric Clinics of North America, 1999, 8, 481-496.
6. Barr CL, Sandor P: Current status of genetic studies of Gilles de la Tourette syndrome. Canadian Journal of Psychiatry, 1998, 43, 351-357.
7. Garvey MA, Giedd J, Swedo S: PANDAS: the search for environmental triggers of pediatric neuropsychiatric disorders. Lessons from rheumatic fever. Journal of Child Neurology, 1998, 13, 413-423. (Pubitemid 28473471)
8. Swedo SE, Leonard HL, Garvey M, Mittleman B, Allen AJ, Perlmutter S, et al.: Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections: clinical description of the first 50 cases. The American Journal of Psychiatry, 1998, 155, 264-271. (Pubitemid 28074291)
9. American Psychiatric Association: DSM-IV-TR. Manuale diagnostico e statistico dei disturbi mentali.Text Revision. Masson, Milano, 2005.
10. Torres AR, Lima MC: Epidemiology of obsessive-compulsive disorder: a review. Revista Brasileira de Psiquiatria, 2005, 27, 237-242.
11. Aouizerate B, Rotgé JY, Bioulac B, Tignol J: Present contribution of neurosciences to a new clinical reading of obsessive-compulsive disorder. Encephale, 2007, 33, 203-210. (Pubitemid 46787709)
12. Kim CH, Cheon KA, Koo MS, Ryu YH, Lee JD, Chang JW, et al.: Dopamine transporter density in the basal ganglia in obsessive-compulsive disorder, measured with [123I]IPT SPECT before and after treatment with serotonin reuptake inhibitors. Neuropsychobiology, 2007, 55, 156-162.
13. Denys D, Zohar J, Westenberg HG: The role of dopamine in obsessive-compulsive disorder: preclinical and clinical evidence. Journal of Clinical Psychiatry, 2004, 65 (suppl 14), 11-17.
14. Coetzer BR: Obsessive-compulsive disorder following brain injury: a review. International Journal of Psychiatry in Medicine, 2004, 34, 363-377. (Pubitemid 40381472)
15. Bloch MH, Landeros-Weisenberger A, Kelmendi B, Coric V, Bracken MB, Leckman JF: A systematic review: antipsychotic augmentation with treatment refractory obsessive-compulsive disorder. Molecular Psychiatry, 2006, 11, 622-632. (Pubitemid 43989810)
16. Bonelli RM, Cummings JL: Frontal-subcortical circuitry and behavior. Dialogues in Clinical Neuroscience, 2007, 9, 141-151.
17. st Century. Clinical infectious diseases: an official publication of the Infectious Diseases Society of America, 2001, 33, 806-814.
18. Bouteille EM (ed): Traité de la Choree, ou Danse de St. Guy. Vincard, Paris, 1810.
19. Ayoub EM, Wannamaker LW: Streptococcal antibody titers in Sydenham's chorea. Pediatrics, 1966, 38, 946-956.
20. Stollerman GH (ed): Rheumatic fever and streptococcal infection. Grune & Stratton, New York, 1975.
21. Husby G, van de Rijn I, Zabriskie JB, Abdin ZH, Williams RC: Antibodies reacting with cytoplasm of subthalamic and caudate nuclei neurons in chorea and acute rheumatic fever. The Journal of Experimental Medicine, 1976, 144, 1094-1110.
22. Bronze MS, Dale JB: Epitopes of streptococcal M proteins that evoke antibodies that cross-react with human brain. Journal of Immunology, 1993, 151, 2820-2828.
23. Moore DP: Neuropsychiatric aspects of Sydenham's chorea: a comprehensive review. The Journal of Clinical Psychiatry, 1996, 57, 407-414.
24. Church AJ, Cardoso F, Dale RC, Lees AJ, Thompson EJ, Giovannoni G: Anti-basal ganglia antibodies in acute and persistent Sydenham's chorea. Neurology, 2002, 59, 227-231.
25. Church AJ, Dale RC, Cardoso F, Candler PM, Chapman MD, Allen ML, et al.: CSF serum immune parameters in Sydenham's chorea: evidence of an autoimmune syndrome? Journal of Neuroimmunology, 2003, 136, 149-153.
26. Swedo SE, Leonard HL, Kiessling LS: Speculations on antineuronal antibody-mediated neuropsychiatric disorders of childhood. Pediatrics, 1994, 93, 323-326.
27. Giedd JN, Rapoport JL, Kruesi MJP, Parker C, Schapiro MB, Allen AJ, et al.: Sydenham's chorea: magnetic resonance imaging of the basal ganglia. Neurology, 1995, 45, 2199-2202. (Pubitemid 27100248)
28. Colony HS, Malamud N: Sydenham's chorea: a clinicopathologic study. Neurology, 1956, 6, 672-676.
29. Greenfield JG, Wolfsohn JM:The pathology of Sydenham's chorea. The Lancet, 1922, 32, 603-606.
30. Swedo SE, Rapoport JL, Cheslow DL, Leonard HL, Ayoub EM, Hosier DM, et al.: High prevalence of obsessive compulsive symptoms in patients with Sydenham's chorea. The American Journal of Psychiatry, 1989, 146, 246-249.
31. Fitzgerald KD, Moore GJ, Paulson LA, Stewart CM, Rosenberg DR: Proton spectroscopic imaging of the thalamus in treatmentnaive pediatric obsessive-compulsive disorder. Biological Psychiatry, 2000, 47, 174-182.
32. Alptekin K, Degirmenci B, Kivircik B, Durak H, Yemez B, Derebek E, et al.: Tc-99m HMPAO brain perfusion SPECT in drug-free obsessive-compulsive patients without depression. Psychiatry Research, 2001, 107, 51-56.
33. Stein DJ: Obsessive-compulsive disorder. The Lancet, 2002, 360, 397-405.
34. Mindus P, Nyman H: Normalization of personality characteristics in patients with incapacitating anxiety disorders after capsulotomy. Acta Psychiatrica Scandinavica, 1991, 83, 283-291.
35. Dougherty DD, Baer L, Cosgrove GR, Cassem EH, Price BH, Nierenberg AA, et al.: Prospective long-term follow-up of 44 patients who received cingulotomy for treatment-refractory obsessive-compulsive disorder. The American Journal of Psychiatry, 2002, 159, 269-275. (Pubitemid 34126905)
36. Creak M, Guttman E: Chorea, tics, compulsive utterances. Journal of Medical Science, 1935, 81, 834-839.
37. Kerbeshian J, Burd L, Pettit R: A possible post-streptococcal movement disorder with chorea and tics. Developmental Medicine and Child Neurology, 1990, 32, 642-644. (Pubitemid 20211475)
38. Mercadante MT, Busatto GF, Lombroso PJ, Prado L, Rosario-Campos MC, do Valle R, et al.: The psychiatric symptoms of rheumatic fever. The American Journal of Psychiatry, 2000, 157, 2036-2038.
39. Kiessling LS, Marcotte AC, Culpepper L: Antineuronal antibodies in movement disorders. Pediatrics, 1993, 92, 39-43.
40. Swedo SE, Leonard HL, Schapiro MB, Casey BJ, Mannheim GB, Lenane MC, et al.: Sydenham's chorea: physical and psychological symptoms of St. Vitus dance. Pediatrics, 1993, 91, 706-713.
41. Allen AJ, Leonard HL, Swedo SE: Case study: a new infection-triggered autoimmune subtype of pediatric DOC and Tourette's Syndrome. Journal of the American Academy of Child and Adolescent Psychiatry, 1995, 34, 307-311.
42. Allen AJ: Group A streptococcal infections and childhood neuropsychiatric disorders. CNS Drugs, 1997, 8, 267-275.
43. Swedo SE, Leonard HL, Mittleman BB, Allen AJ, Rapoport JL, Dow SP, et al.: Identification of children with pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections by a marker associated with rheumatic fever. The American Journal of Psychiatry, 1997, 154, 110-112.
44. Swedo SE, Leonard HL, Garvey M, Mittleman B, Allen AJ, Perlmutter S, et al.: Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections: clinical description of the first 50 cases. The American Journal of Psychiatry, 1998, 155, 264-271. (Pubitemid 28074291)
45. Leonard HL, Swedo SE, Lenane MC, Rettew DC, Hamburger SD, Bartko JJ, et al.: A 2- to 7-year follow-up study of 54 obsessive compulsive children and adolescents. Archives of General Psychiatry, 1993, 50, 429-439. (Pubitemid 23169936)
46. Murphy ML, Pichichero ME: Prospective identification and treatment of children with pediatric autoimmune neuropsychiatric disorder associated with group A streptococcal infection. Archives of Pediatric and Adolescent Medicine, 2002, 156, 356-361.
47. Dale RC, Church AJ, Benton S, Surtees RA, Lees A, Thompson EJ, et al.: Post-streptococcal autoimmune dystonia with isolated bilateral striatal necrosis. Developmental Medicine and Child Neurology, 2002, 44, 485-489. (Pubitemid 34808756)
48. Di Fazio MP, Morales J, Davis R: Acute myoclonus secondary to group A beta-hemolytic streptococcus infection: a PANDAS variant. Journal of Child Neurology, 1998, 13, 516-518. (Pubitemid 28483715)
49. Albin RL, Young AB, Penney JB: The functional anatomy of basal ganglia disorders. Trends in Neurosciences, 1989, 12, 366-375.
50. Berrios X, Quesney F, Morales A, Blazquez J, Bisno AL: Are all recurrences of 'pure' Sydenham chorea true recurrences of acute rheumatic fever? The Journal of Pediatrics, 1985, 107, 867-872.
51. Ercan TE, Ercan G, Severge B, Arpaozu M, Karasu G: Mycoplasma pneumoniae infection and obsessive-compulsive disease: a case report. Journal of Child Neurology, 2008, 23, 338-340. (Pubitemid 351247629)
52. Church AJ, Dale RC, Lees AJ, Giovannoni G, Robertson MM: Tourette's syndrome: a cross sectional study to examine the PANDAS hypothesis. Journal of Neurology, Neurosurgery, and Psychiatry, 2003, 74, 602-607. (Pubitemid 36528904)
53. Mell LK, Davis RL, Owens D: Association between streptococcal infection and obsessive compulsive disorder, Tourette's syndrome, and tic disorder. Pediatrics, 2005, 116, 56-60.
54. Lougee L, Perlmutter SJ, Nicolson R, Garvey MA, Swedo SE: Psychiatric disorders in first-degree relatives of children with pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS). Journal of the American Academy of Child and Adolescent Psychiatry, 2000, 39, 1120-1126. (Pubitemid 30676820)
55. Murphy TK, Goodman WK, Fudge MW, Williams RC Jr, Ayoub EM, Dalal M, et al.: B lymphocyte antigen D8/17: a peripheral marker for childhood-onset obsessive-compulsive disorder and Tourettes syndrome. The American Journal of Psychiatry, 1997, 154, 402-407. (Pubitemid 27098292)
56. Murphy TK, Benson N, Zaytoun A, Yang M, Braylan R, Ayoub E, et al.: Progress toward analysis of D8/17 binding to B cells in children with obsessive compulsive disorder and/or chronic tic disorder. Journal of Neuroimmunology, 2001, 120, 146-151. (Pubitemid 33016734)
57. Inoff-Germain G, Rodríguez RS, Torres-Alcantara S, Díaz-Jimenez MJ, Swedo SE, Rapoport JL: An immunological marker (D8/17) associated with rheumatic fever as a predictor of childhood psychiatric disorders in a community sample. Journal of Child Psychology and Psychiatry and Allied Disciplines, 2003, 44, 782-790.
58. Kochman F, Hantouche EG, Karila L, Bayart D, Bailly D: Obsessive-compulsive disorder in children induced by streptococcal infection. Presse Médicale, 2001, 30, 1747-1751. (Pubitemid 33104628)
59. Bodner SM, Morshed SA, Peterson BS: The question of PANDAS in adults. Biological Psychiatry, 2001, 49, 807-810.
60. Church AJ, Dale RC: Antistreptolysin-O titers: implications for adult PANDAS. The American Journal of Psychiatry, 2002, 159, 320.
61. National Institute of Mental Health: http://intramural.nimh.nih.gov/pdn/ web.htm, 2006.
62. Taranta A, Stollerman GH: The relationship of Sydenham's chorea to infection with group A streptococci. The American Journal of Medicine, 1956, 20, 170-175.
63. Swedo SE: Sydenham's chorea. A model for childhood autoimmune neuropsychiatric disorders. JAMA: the Journal of the American Medical Association, 1994, 272, 1788-1791.
64. Snider LA, Swedo SE: PANDAS: current status and directions for research. Molecular Psychiatry, 2004, 9, 900-907. (Pubitemid 39381954)
65. Knopf PM, Harling-Berg CJ, Cserr HF, Basu D, Sirulnick EJ, Nolan SC, et al.: Antigen-dependent intrathecal antibody synthesis in the normal rat brain: tissue entry and local retention of antigen-specific B cells. Journal of Immunology, 1998, 161, 692-701. (Pubitemid 28323531)
66. Pavone P, Bianchini R, Parano E, Incorpora G, Rizzo R, Mazzone L, et al.: Anti-brain antibodies in PANDAS versus uncomplicated streptococcal infection. Pediatric Neurology, 2004, 30, 107-110.
67. Singer HS, Hong JJ, Yoon DY, Williams PN: Serum autoantibodies do not differentiate PANDAS and Tourette syndrome from controls. Neurology, 2005, 65, 1701-1707.
68. Kiessling LS, Marcotte AC, Culpepper L: Antineuronal antibodies: tics and obsessive-compulsive symptoms. Journal of developmental and behavioral pediatrics, 1994, 15, 421-425.
69. Singer HS, Giuliano JD, Hansen BH, Hallett JJ, Laurino JP, Benson M, et al.: Antibodies against human putamen in children with Tourette syndrome. Neurology, 1998, 50, 1618-1624. (Pubitemid 28283226)
70. Morshed SA, Parveen S, Leckman JF, Mercadante MT, Bittencourt Kiss MH, Miguel EC, et al.: Antibodies against neural nuclear cytoskeletal, and streptococcal epitopes in children adults with Tourette's syndrome, Sydenham's chorea, and autoimmune disorders. Biological Psychiatry, 2001, 50, 566-577.
71. Wendlandt JT, Grus FH, Hansen BH, Singer HS: Striatal antibodies in children with Tourette's syndrome: multivariate discriminant analysis of IgG repertoires. Journal of Neuroimmunology, 2001, 119, 106-113.
72. Loiselle CR, Wendlandt JT, Rohde CA, Singer HS: Antistreptococcal, neuronal, and nuclear antibodies in Tourette syndrome. Pediatric Neurology, 2003, 28, 119-125.
73. Hoffman KL, Hornig M, Yaddanapudi K, Jabado O, Lipkin WI: A murine model for neuropsychiatric disorders associated with group A beta-hemolytic streptococcal infection. The Journal of Neuroscience: the official journal of the Society for Neuroscience, 2004, 24, 1780-1791. (Pubitemid 38240976)
74. Taylor JR, Morshed SA, Parveen S, Mercadante MT, Scahill L, Peterson BS, et al.: An animal model of Tourette's syndrome. The American Journal of Psychiatry, 2002, 159, 657-660.
75. Mima T, Matsuoka T, Hallett M: Functional coupling of human right and left cortical motor areas demonstrated with partial coherence analysis. Neuroscience Letters, 2000, 287, 93-96. (Pubitemid 30353055)
76. Dale RC, Heyman I, Giovannoni G, Church AW: Incidence of anti-brain antibodies in children with obsessive-compulsive disorder. The British Journal of Psychiatry: the Journal of Mental Science, 2005, 187, 314-319. (Pubitemid 41442381)
77. Kirvan CA, Swedo SE, Snider LA, Cunningham MW: Antibody-mediated neuronal cell signaling in behavior and movement disorders. Journal of Neuroimmunology, 2006, 179, 173-179.
78. Mcintyre JA, Wagenknecht DR: Anti-phosphatidylethanolamine (aPE) antibodies: a survey, 2000, 15, 185-193.
79. Sokol DK, McGuire LM, Johnson NS, Wagenknecht DR, McIntyre JA: Obsessive-compulsive disorder and central nervous system autoimmunity. The British Journal of Psychiatry: the Journal of Mental Science, 2006, 189, 190-191.
80. Sokol DK, McIntyre JA, Short RA, Gutt J, Wagenknecht DR, Biller J, et al.: Henoch-Schönlein purpura and stroke: antiphosphatidylethanolamine antibody in CSF and serum. Neurology, 2000, 55, 1379-1381. (Pubitemid 30829383)
81. Sokol DK, O'Brien RS, Wagenknecht DR, Rao T, McIntyre JA: Antiphospholipid antibodies in blood and cerebrospinal fluids of patients with psychosis. Journal of Neuroimmunology, 2007, 190, 151-156. (Pubitemid 47625611)
82. Maes M, Meltzer HY, Bosmans E: Psychoimmune investigation in obsessive-compulsive disorder: assays of plasma transferrin, IL-2 and IL-6 receptor, and IL-1β and IL-6 concentrations. Neuropsychobiology, 1994, 30, 57-60. (Pubitemid 24284802)
83. Brambilla F, Perna G, Bellodi L, Arancio C, Bertani A, Perini G, et al.: Plasma interleukin-1β and tumor necrosis factor concentrations in obsessivecompulsive disorders. Biological Psychiatry, 1997, 42, 976-981. (Pubitemid 27496427)
84. Kronfol Z, Remick DG: Cytokines and the brain: implications for clinical psychiatry. The American Journal of Psychiatry, 2000, 157, 683-694. (Pubitemid 30249643)
85. Mittleman BB, Castellanos FX, Jacobsen LK, Rapoport JL, Swedo SE, Shearer GM: Cerebrospinal fluid cytokines in pediatric neuropsychiatric disease. Journal of Immunology, 1997, 159, 2994-2999 (Pubitemid 127681323)
86. Weizman R, Laor N, Barber Y, Hermesh H, Notti I, Djaldetti M, et al.: Cytokine production in obsessive-compulsive disorder. Biological Psychiatry, 1996, 40, 908-912.
87. Denys D, Fluitman S, Kavelaars A, Heijnen C, Westenberg H: Decreased TNF-α and NK activity in obsessive compulsive disorder. Psychoneuroendocrinology, 2004, 29, 945-952. (Pubitemid 38716121)
88. Monteleone P, Catapano F, Fabrazzo M, Tortorella A, Maj M: Decreased blood levels of tumor necrosis factor α in patients with obsessive-compulsive disorder. Neuropsychobiology, 1998, 37, 182-185. (Pubitemid 28256877)
89. Ravindran AV, Griffiths J, Merali Z, Anisman H: Circulating lymphocyte subsets in obsessive compulsive disorder, major depression and normal controls. Journal of Affective Disorders, 1999, 52, 1-10. (Pubitemid 29232028)
90. Vassalli P: The pathophysiology of tumor necrosis factors. Annual Review of Immunology, 1992, 10, 411-452.
91. Maier SF, Watkins LR: Cytokines for psychologists: implications of bidirectional immune-to-brain communication for understanding behavior, mood, and cognition. Psychological Review, 1998, 105, 83-107.
92. Kishimoto T: Interleukin-6 and its receptor in autoimmunity. Journal of Autoimmunity, 1992, 5 (suppl A), 123-132.
93. Schöbitz B, de Kloet ER, Sutanto W, Holsboer F: Cellular localization of interleukin 6 mRNA and interleukin 6 receptor mRNA in rat brain. European Journal of Neuroscience, 1993, 5, 1426-1435. (Pubitemid 23325225)
94. Konuk N, Tekin IO, Ozturk U, Atik L, Atasoy N, Bektas S, et al.: Plasma levels of tumor necrosis factor-α and interleukin-6 in obsessive-compulsive disorder. Mediators of Inflammation, 2007, article ID 65704.
95. Peterson BS, Leckman JF, Tucker D, Scahill L, Staib L, Zhang H, et al.: Preliminary findings of antistreptococcal antibody titers and basal ganglia volumes in tic, obsessive-compulsive, and attention deficit/hyperactivity disorders. Archives of General Psychiatry, 2000, 57, 364-372. (Pubitemid 30202327)
96. Giedd JN, Rapoport JL, Garvey MA, Perlmutter S, Swedo SE: MRI assessment of children with obsessive-compulsive disorder or tics associated with streptococcal infection. The American Journal of Psychiatry, 2000, 157, 281-283. (Pubitemid 30080914)
97. Giedd JN, Rapoport JL, Leonard HL, Richter D, Swedo SE: Case study: acute basal ganglia enlargement and obsessive-compulsive symptoms in an adolescent boy. Journal of the American Academy of Child and Adolescent Psychiatry, 1996, 35, 913-915. (Pubitemid 26230925)
98. Hamilton CS, Swedo SE: Autoimmune-mediated, childhood onset obsessive-compulsive disorder and tics: a review. Clinical Neuroscience Research, 2001, 1, 61-68.
99. Perlmutter SJ, Leitman SF, Garvey MA, Hamburger S, Feldman E, Leonard HL, et al.: Therapeutic plasma exchange and intravenous immunoglobulin for obsessive-compulsive disorder tic disorders in childhood. The Lancet, 1999, 354, 1153-1158. (Pubitemid 29460444)
100. Elevli M, Celebi A, Tombul T, Gokalp AS: Cardiac involvement in Sydenham's chorea: clinical and doppler echocardiographic findings. Acta Paediatrica. 1999, 88, 1074-1077.
101. Nausieda PA, Grossman BJ, Koller WC, Weiner WJ, Klawans HL: Sydenham chorea: an update. Neurology, 1980, 30, 331-334.
102. Minich LL, Tani LY, Pagotto LT, Shaddy RE, Veasy LG: Doppler echocardiography distinguishes between physiologic and pathologic "silent" mitral regurgitation in patients with rheumatic fever. Clinical Cardiology, 1997, 20, 924-926.
103. Snider LA, Sachdev V, MacKaronis JE, Saint Peter M, Swedo SE: Echocardiographic findings in the PANDAS subgroup. Pediatrics, 2004, 114, 748-751.
104. Cardona F, Ventriglia F, Cipolla O, Romano A, Creti R, Orefici G: A post-streptococcal pathogenesis in children with tic disorders is suggested by a color Doppler echocardiographic study. European Journal of Paediatric Neurology, 2007, 11, 270-276. (Pubitemid 47194441)
105. Leonard HL, Swedo SE: Paediatric autoimmune neuropsychiatric disorders associated with streptococcal infection (PANDAS). The international Journal of Neuropsychopharmacology, 2001, 4, 191-198.
106. El-Ghariani K, Unswort DJ: Therapeutic apheresisplasmapheresis. Clinical Medicine, 2006, 6, 343-347.
107. Sadhasivam S, Litman RS: Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections-anesthetic implications and literature review. Pediatric Anesthesia, 2006, 16, 573-577.
108. Beşiroǧlu L, Aǧargün MY, Ozbebit O, Sözen M, Dilek I, Güleç M: Therapeutic response to plasmapheresis in four cases with obsessive-compulsive disorder and tic disorder triggered by streptococcal infections. Turkish Journal of Psychiatry, 2007, 18, 270-276.
109. Elia J, Dell ML, Friedman DF, Zimmerman RA, Balamuth N, Ahmed AA, et al.: PANDAS with catatonia: a case report, therapeutic response to lorazepam and plasmapheresis. Journal of the American Academy of Child and Adolescent Psychiatry, 2005, 44, 1145-1150. (Pubitemid 41508126)
110. Nicolson R, Swedo SE, Lenane M, Bedwell J, Wudarsky M, Gochman P, et al.: An open trial of plasma exchange in childhood-onset obsessive-compulsive disorder without poststreptococcal exacerbations. Journal of the American Academy of Child and Adolescent Psychiatry, 2000, 39, 1313-1315. (Pubitemid 30746495)
111. Orvidas LJ, Slattery MJ: Pediatric autoimmune neuropsychiatric disorders and streptococcal infections: role of otolaryngologist. The Laryngoscope, 2001, 111, 1515-1519.
112. Arostegui S, Aguero JA, Escar C: PANDAS tras amigdalectomia. Anales del Sistema Sanitario de Navarra. 2003, 26, 287-290.
113. Jonasson G, Wilkinson SR: Prednisolone-induced obsessive- compulsivebehaviour in a child. Tidsskrift for den Norske Laegeforening, 1993, 113, 3162-3166.
114. Garvey MA, Perlmutter SJ, Allen AJ, Hamburger S, Lougee L, Leonard HL, et al.: A pilot study of penicillin prophylaxis for neuropsychiatric exacerbations triggered by streptococcal infections. Biological Psychiatry, 1999, 45, 1564-1571. (Pubitemid 29292832)
115. Snider LA, Lougee L, Slattery M, Grant P, Swedo SE: Antibiotic Prophylaxis with Azithromycin or Penicilin for Childhood-Onset Neuropsychiatric Disorders. Biological Psychiatry, 2005, 57, 788-792. (Pubitemid 40487923)
116. Gilbert D, Gerber MA: Regarding "Antibiotic prophylaxis with Azithromycin or Penicillin for Childhood-Onset Neuropsychiatric Disorders". Biological Psychiatry, 2005, 58, 916.
117. Arnold PD, Richter MA: Is obsessive-compulsive disorder an autoimmune disease? CMAJ: Canadian Medical Association Journal, 2001, 165, 1353-1358. (Pubitemid 33044068)
118. Snider LA, Swedo SE: Childhood-onset obsessive-compulsive disorder and tic disorders: case report and literature review. Journal of Child and Adolescent Psychopharmacology, 2003, 13 (suppl 1), 81-88.