Incidence of anti-brain antibodies in children with obsessive-compulsive disorder

British Journal of Psychiatry

Volumn 187, Issue OCT., 2005, Pages 314-319

  Dale, Russell C ^a,b   Heyman, Isobel ^a,c   Giovannoni, Gavin ^b   Church, Andrew J ^b  

^a GREAT ORMOND STREET HOSPITAL   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN ANTIBODY;

ADOLESCENT; ANTIGEN BINDING; ARTICLE; AUTOIMMUNITY; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; IMMUNOBLOTTING; INCIDENCE; MALE; OBSESSIVE COMPULSIVE DISORDER; PATHOGENESIS; STREPTOCOCCUS; WESTERN BLOTTING;

EID: 26644435516     PISSN: 00071250     EISSN: None     Source Type: Journal    
DOI: 10.1192/bjp.187.4.314     Document Type: Article

References (24)

1. American Psychiatric Association (1994) Diagnostic and Statistical Manual of Mental Disorders (4th edn) (DSM-IV). Washington, DC: APA.
2. Asbahr, F. R., Ramos, R. T., Negrao, A. B., et al (1999) Case series: increased vulnerability to obsessive-compulsive symptoms with repeated episodes of Sydenham chorea. Journal of the American Academy of Child and Adolescent Psychiatry, 38, 1522-1525.
3. Church, A. J., Cardoso, F., Dale, R. C., et al (2002) Anti-basal ganglia antibodies in acute and persistent Sydenham's chorea. Neurology, 59, 227-231.
4. Church, A. J., Dale, R. C., Cardoso, F., et al (2003a) CSF and serum immune parameters in Sydenham's chorea: evidence of an autoimmune syndrome? Journal of Neuroimmunology, 136, 149-153.
5. Church, A. J., Dale, R. C., Lees, A. J., et al (2003b) Tourette's syndrome: a cross sectional study to examine the PANDAS hypothesis. Journal of Neurobiology, Neurosurgery and Psychiatry, 74, 602-607.
6. Dale, R. C., Church, A. J., Surtees, R. A., et al (2004) Encephalitis lethargica syndrome: 20 new cases and evidence of basal ganglia autoimmunity. Brain, 127, 21-33.
7. Giedd, J. N., Rapoport, J. L., Kruesi, M. J., et al (1995) Sydenham's chorea: magnetic resonance imaging of the basal ganglia. Neurology, 45, 2199-2202.
8. Hallett, J. J., Harling-Berg, C. J., Knopf, P. M., et al (2000) Anti-striatal antibodies in Tourette syndrome cause neuronal dysfunction. Journal of Neuroimmunology, III, 195-202.
9. Hoekstra, P. J., Horst, G., Limburg, P. C., et al (2003) Increased seroreactivity in tic disorder patients to a 60 kDa protein band from a neuronal cell line. Journal of Neuroimmunology, 141, 118-124.
10. Husby, G., van de Rijn, I., Zabriskie, J. B., et al (1976) Antibodies reacting with cytoplasm of subthalamic and caudate nuclei neurons in chorea and acute rheumatic fever. Journal of Experimental Medicine, 144, 1094-1110.
11. Kiessling, L. S., Marcotte, A. C. & Culpepper, L. (1993) Antineuronal antibodies in movement disorders. Pediatrics, 92, 39-43.
12. Kiessling, L. S., Marcotte, A. C. & Culpepper, L. (1994) Antineuronal antibodies: tics and obsessive-compulsive symptoms. Journal of Developmental and Behavioural Pediatrics, 15, 421-425.
13. Kirvan, C. A., Swedo, S. E., Heuser, J. S., et al (2003) Mimicry and autoantibody-mediated neuronal cell signalling in Sydenham chorea. Nature Medicine, 9, 914-920.
14. Kurlan, R. & Kaplan, E. L. (2004) The pediatric autoimmune neuropsychiatric disorders associated with streptococcal infection (PANDAS) etiology for tics and obsessive-compulsive symptoms; hypothesis or entity? Practical considerations for the clinician. Pediatrics, 113, 883-886.
15. Mercadante, M. T., Busatto, G. F., Lombroso, P. J., et al (2000) The psychiatric symptoms of rheumatic fever. American Journal of Psychiatry, 157, 2036-2038.
16. Murphy, T. K., Goodman, W. K., Fudge, M. W., et al (1997) B lymphocyte antigen D8/17: a peripheral marker for childhood-onset obsessive-compulsive disorder and Tourette's syndrome? American Journal of Psychiatry, 154, 402-407.
17. Pauls, D. L., Alsobrook, J. P., Goodman, W., et al (1995) A family study of obsessive-compulsive disorder. American Journal of Psychiatry, 152, 76-84.
18. Perlmutter, S. J., Leitman, S. F., Garvey, M. A., et al (1999) Therapeutic plasma exchange and intravenous immunoglobulin for obsessive-compulsive disorder and tic disorders in childhood. Lancet, 354, 1153-1158.
19. Scahill, L., Riddle, M. A., McSwiggin-Hardin, M., et al (1997) Children's Yale-Brown Obsessive Compulsive Scale: reliability and validity. Journal of the American Academy of Child and Adolescent Psychiatry, 36, 844-852.
20. Spaun, J., Bentzon, M. W., Olesen Larsen, S., et al (1961) International standard for antistreptolysin O. Bulletin of the World Health Organization, 24, 271-279.
21. Stein, D. J. (2002) Obsessive-compulsive disorder. Lancet, 360, 397-405.
22. Swede, S. E., Leonard, H. L., Garvey, M., et al (1998) Pediatric autoimmune neuropsychatric disorders associated with streptococcal infections: clinical description of the first 50 cases. American Journal of Psychiatry, 155, 264-271.
23. Swedo, S. E., Leonard, H. L. & Rapoport, J. L. (2004) The pediatric autoimmune neuropsychiatric disorders associated with streptococcal infection (PANDAS) subgroup: separating fact from fiction. Pediatrics, 113, 907-911.
24. Von Economo, C. (1931) Encephalitis Lethargica: Its Sequelae and Treatment (transl. K. O. Newman). Oxford: Oxford University Press.