A catch-up validation study on reconstructed human epidermis (SkinEthic™ RHE) for full replacement of the Draize skin irritation test

Toxicology in Vitro

Volumn 24, Issue 1, 2010, Pages 257-266

  Alépée, Nathalie ^a   Tornier, Carine ^b   Robert, Cécile ^c   Amsellem, Carole ^d   Roux, Marie Hélène ^e   Doucet, Olivier ^c   Pachot, Jean ^e   Méloni, Marisa ^f   de Brugerolle de Fraissinette, Anne ^b  

^a L ORÉAL RECHERCHE   (France)

^b SkinEthic Laboratories   (France)

^c Coty ^*  (Monaco)

^d EPISKIN SNC   (France)

^e Oroxcell   (France)

^f VitroScreen   (Italy)

Author keywords

"42 bis" Test method; In vitro reconstructed human tissue (RhT); Reconstructed human epidermis (RHE); Skin irritation; SkinEthic; Validation ECVAM

Indexed keywords

IRRITANT AGENT;

ARTICLE; BIOLOGICAL MODEL; CELL VIABILITY; CONTROLLED STUDY; EPIDERMIS; IN VITRO STUDY; QUALITY CONTROL; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; SKIN IRRITATION; TISSUE ENGINEERING; TOXICITY TESTING; VALIDATION PROCESS;

ORYCTOLAGUS CUNICULUS;

EID: 72149114607     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2009.08.024     Document Type: Article

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