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Volumn 45, Issue 1, 2010, Pages 90-97
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Discovery of colon tumor cell growth inhibitory agents through a combinatorial approach
a
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Author keywords
Growth inhibition; Multi component reaction; Phosphodiesterase inhibition
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Indexed keywords
2 IMINO 4 (4 METHOXYPHENYL) 6 (THIOPHEN 3 YL) 1,2 DIHYDROPYRIDINE 3 CARBONITRILE;
2 IMINO 4 PHENYL 6 (THIOPHEN 3 YL) 1,2 DIHYDROPYRIDINE 3 CARBONITRILE;
2 IMINO 6 PHENYL 4 (THIOPHEN 3 YL) 1,2 DIHYDROPYRIDINE 3 CARBONITRILE;
2 OXO 6 PHENYL 4 THIOPHEN 3 YL 1,2 DIHYDROPYRIDINE 3 CARBONITRILE;
4 (2 ETHOXYPHENYL) 2 IMINO 6 (THIOPHEN 3 YL) 1,2 DIHYDROPYRIDINE 3 CARBONITRILE;
4 (2 ETHOXYPHENYL) 2 OXO 6 THIOPHEN 3 YL 1,2 DIHYDROPYRIDINE 3 CARBONITRILE;
4 (2 HYDROXYPHENYL) 2 OXO 6 THIOPHEN 3 YL 1,2 DIHYDROPYRIDINE 3 CARBONITRILE;
4 (2 METHOXYPHENYL) 2 OXO 6 THIOPHEN 3 YL 1,2 DIHYDROPYRIDINE 3 CARBONITRILE;
4 (3 CHLOROPHENYL) 2 IMINO 6 PHENYL 1,2 DIHYDROPYRIDINE 3 CARBONITRILE;
4 (3 CHLOROPHENYL) 2 OXO 6 PHENYL 1,2 DIHYDROPYRIDINE 3 CARBONITRILE;
4 (4 CHLOROPHENYL) 2 OXO 6 THIOPHEN 3 YL 1,2 DIHYDROPYRIDINE 3 CARBONITRILE;
4 (4 ETHOXYPHENYL) 2 IMINO 6 (THIOPHEN 3 YL) 1,2 DIHYDROPYRIDINE 3 CARBONITRILE;
4 (4 ETHOXYPHENYL) 2 OXO 6 THIOPHEN 3 YL 1,2 DIHYDROPYRIDINE 3 CARBONITRILE;
4 (4 METHOXYPHENYL) 2 OXO 6 THIOPHEN 3 YL 1,2 DIHYDROPYRIDINE 3 CARBONITRILE;
6 (2 BROMOPHENYL) 4 (2 HYDROXYPHENYL) 2 IMINO 1,2 DIHYDROPYRIDINE 3 CARBONITRILE;
6 (2 BROMOPHENYL) 4 (2 HYDROXYPHENYL) 2 OXO 1,2 DIHYDROPYRIDINE 3 CARBONITRILE;
6 (3 BROMOPHENYL) 4 (2 HYDROXYPHENYL) 2 IMINO 1,2 DIHYDROPYRIDINE 3 CARBONITRILE;
6 (3 BROMOPHENYL) 4 (2 HYDROXYPHENYL) 2 OXO 1,2 DIHYDROPYRIDINE 3 CARBONITRILE;
6 (4 BROMOPHENYL) 4 (2 CHLOROPHENYL) 2 IMINO 1,2 DIHYDROPYRIDINE 3 CARBONITRILE;
6 (4 BROMOPHENYL) 4 (2 CHLOROPHENYL) 2 OXO 1,2 DIHYDROPYRIDINE 3 CARBONITRILE;
6 (4 BROMOPHENYL) 4 (2 HYDROXYPHENYL) 2 IMINO 1,2 DIHYDROPYRIDINE 3 CARBONITRILE;
6 (4 BROMOPHENYL) 4 (2 HYDROXYPHENYL) 2 OXO 1,2 DIHYDROPYRIDINE 3 CARBONITRILE;
6 (4 BROMOPHENYL) 4 (2,4 DIMETHOXYPHENYL) 2 IMINO 1,2 DIHYDROPYRIDINE 3 CARBONITRILE;
6 (4 BROMOPHENYL) 4 (2,4 DIMETHOXYPHENYL) 2 OXO 1,2 DIHYDROPYRIDINE 3 CARBONITRILE;
6 (4 BROMOPHENYL) 4 (2,5 DIMETHOXYPHENYL) 2 IMINO 1,2 DIHYDROPYRIDINE 3 CARBONITRILE;
6 (4 BROMOPHENYL) 4 (2,5 DIMETHOXYPHENYL) 2 OXO 1,2 DIHYDROPYRIDINE 3 CARBONITRILE;
6 (4 BROMOPHENYL) 4 (3 CHLOROPHENYL) 2 IMINO 1,2 DIHYDROPYRIDINE 3 CARBONITRILE;
6 (4 BROMOPHENYL) 4 (3 CHLOROPHENYL) 2 OXO 1,2 DIHYDROPYRIDINE 3 CARBONITRILE;
ANTINEOPLASTIC AGENT;
UNCLASSIFIED DRUG;
UNINDEXED DRUG;
ARTICLE;
CANCER INHIBITION;
COLON TUMOR;
DRUG SYNTHESIS;
HUMAN;
HUMAN CELL;
IC 50;
ONE POT SYNTHESIS;
TUMOR CELL;
ANIMALS;
ANTINEOPLASTIC AGENTS;
CELL PROLIFERATION;
COLONIC NEOPLASMS;
COMBINATORIAL CHEMISTRY TECHNIQUES;
CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 3;
DRUG DISCOVERY;
HT29 CELLS;
HUMANS;
INHIBITORY CONCENTRATION 50;
ISOENZYMES;
MODELS, MOLECULAR;
MOLECULAR CONFORMATION;
PYRIDONES;
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EID: 72049114166
PISSN: 02235234
EISSN: 17683254
Source Type: Journal
DOI: 10.1016/j.ejmech.2009.09.029 Document Type: Article |
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Times cited : (60)
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References (20)
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