Novel cultured porcine corneal irritancy assay with reversibility endpoint

Toxicology in Vitro

Volumn 24, Issue 1, 2010, Pages 231-239

  Piehl, Michelle ^a   Gilotti, Albert ^a   Donovan, Alison ^a   DeGeorge, George ^a   Cerven, Daniel ^a  

^a MB Research Laboratories   (United States)

Author keywords

Alternative assay; Corneal culture; Ocular irritation; Ocular reversibility; Porcine cornea; Replacement assay

Indexed keywords

ALCOHOL; BENZALKONIUM CHLORIDE; DODECYL SULFATE SODIUM; FLUORESCEIN SODIUM; PHOSPHATE BUFFERED SALINE; SODIUM HYDROXIDE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORNEA EPITHELIUM; CORNEA INJURY; EX VIVO STUDY; EYE IRRITATION; HISTOPATHOLOGY; NONHUMAN; PREDICTION; SWINE; TOXICITY TESTING;

ANIMAL TESTING ALTERNATIVES; ANIMALS; BLOOD VESSELS; CELLS, CULTURED; CORNEA; CORNEAL DISEASES; ENDPOINT DETERMINATION; FLUORESCEIN; IRRITANTS; MICROSCOPY, CONFOCAL; ORGAN CULTURE TECHNIQUES; REGIONAL BLOOD FLOW; SWINE;

ANIMALIA; ORYCTOLAGUS CUNICULUS; SUS;

EID: 72049102366     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2009.08.033     Document Type: Article

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