Structure elucidation and enantioselective total synthesis of the HMG-CoA reductase inhibitors FR901512 and FR901516

Synthesis

Volumn , Issue 21, 2009, Pages 3694-3707

  Inoue, Masahiro ^a   Nakada, Masahisa ^a  

^a WASEDA UNIVERSITY   (Japan)

Author keywords

Asymmetric catalysis; Enantioselective synthesis; Nozaki Hiyama reaction; Structure elucidation; Total synthesis

Indexed keywords

ASYMMETRIC CATALYSIS; AVERAGE YIELD; ENANTIOSELECTIVE SYNTHESIS; ENANTIOSELECTIVE TOTAL SYNTHESIS; HMG-COA REDUCTASE INHIBITOR; REACTION STRUCTURES; STATINS; STRUCTURE ELUCIDATION; TOTAL SYNTHESIS;

CATALYSIS; FLUORINE CONTAINING POLYMERS;

SYNTHESIS (CHEMICAL);

FR 901512; FR 901516; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; UNCLASSIFIED DRUG;

CATALYSIS; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOSELECTIVITY; NOZAKI HIYAMA REACTION; RELIABILITY; REVIEW;

EID: 72049101650     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/S-0029-1216980     Document Type: Review

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