Enzymatic acylation and ring-closing olefin metathesis: A convenient strategy for the lactone moiety of compactin and mevinolin

Journal of Organic Chemistry

Volumn 65, Issue 15, 2000, Pages 4779-4781

  Ghosh, Arun K ^a   Lei, Hui ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKENE; COMPACTIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LACTONE; MEVINOLIN;

ACYLATION; ARTICLE; CHEMICAL REACTION; DRUG STRUCTURE; ENANTIOMER; ENZYME ACTIVITY; STEREOCHEMISTRY;

ACYLATION; ALKENES; CATALYSIS; ENZYMES, IMMOBILIZED; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; LACTONES; LIPASE; LOVASTATIN; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; STEREOISOMERISM;

EID: 0034725917     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo000528m     Document Type: Article

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