FR901512, a novel HMG-CoA reductase inhibitor produce by an agonomycetous fungus No. 14919. I. Taxonomy of the producing organism, fermentation, isolation and physico-chemical properties

Journal of Antibiotics

Volumn 57, Issue 4, 2004, Pages 264-270

  Hatori, Hidetaka ^a   Sato, Bunji ^a   Sato, Ikuko ^a   Shibata, Toshihiro ^a   Tsurumi, Yasuhisa ^a   Sakamoto, Kazutoshi ^a   Takase, Shigehiro ^a   Ueda, Hirotsugu ^a   Hino, Motohiro ^a   Fujii, Takashi ^a  

^a ASTELLAS PHARMA INC   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

FR 901512; FR 901516; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CHOLESTEROL SYNTHESIS; CONTROLLED STUDY; DRUG ISOLATION; DRUG PURIFICATION; DRUG STRUCTURE; ENZYME INHIBITION; FERMENTATION; FUNGAL STRAIN; HUMAN; HUMAN CELL; IC 50; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ANALYSIS; TAXONOMY;

EID: 2342620687     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.57.264     Document Type: Article

References (14)

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14. Hatori, H.; B. Sato, I. Sato, T. Shibata, H. Ueda, M. HINO & T. Fijii: FR901512, a novel HMG-CoA reductase inhibitor produced by agonomycetous fungus No. 14919, II. Biological profiles. Manuscript in preparation.