Microglial low-density lipoprotein receptor-related protein 1 mediates the effect of tissue-type plasminogen activator on matrix metalloproteinase-9 activity in the ischemic brain

Journal of Cerebral Blood Flow and Metabolism

Volumn 29, Issue 12, 2009, Pages 1946-1954

  Zhang, Chen ^a   An, Jie ^a,b   Haile, Woldeab B ^a   Echeverry, Ramiro ^a   Strickland, Dudley K ^c   Yepes, Manuel ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SHANDONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

Cerebral ischemia; Low density lipoprotein receptor related protein; Matrix metalloproteinase 9; Microglia; Neurovascular unit; Tissue type plasminogen activator

Indexed keywords

CLAUDIN 5; GELATINASE B; GLUCOSE; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; OXYGEN; PLASMINOGEN; TISSUE PLASMINOGEN ACTIVATOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN EDEMA; BRAIN HYPOXIA; BRAIN ISCHEMIA; CONTROLLED STUDY; DRUG PROTEIN BINDING; ENZYME ACTIVITY; MICROGLIA; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; TIGHT JUNCTION; WILD TYPE;

ANIMALS; BRAIN; BRAIN ISCHEMIA; CELLS, CULTURED; GENE EXPRESSION REGULATION; LDL-RECEPTOR RELATED PROTEIN 1; MATRIX METALLOPROTEINASE 9; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROGLIA; TISSUE PLASMINOGEN ACTIVATOR;

EID: 72049096104     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1038/jcbfm.2009.174     Document Type: Article

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