Detecting drug targets with minimum side effects in metabolic networks

IET Systems Biology

Volumn 3, Issue 6, 2009, Pages 523-533

  Li, Z ^a   Wang, R S ^b   Zhang, X S ^c   Chen, L ^d  

^a BEIJING WUZI UNIVERSITY   (China)

^b RENMIN UNIVERSITY OF CHINA   (China)

^c CHINESE ACADEMY OF SCIENCES   (China)

^d OSAKA SANGYO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

COMPUTATIONAL EXPERIMENT; DRUG DISCOVERY PROCESS; DRUG TARGETS; HIGH-THROUGHPUT TECHNIQUE; HOMO SAPIENS; INTEGER LINEAR PROGRAMMING MODELS; LARGE-SCALE NETWORK; MASSIVE DATA; METABOLIC NETWORK; METABOLIC PATHWAYS; METABOLIC SYSTEMS; OPTIMAL SOLUTIONS; PHARMACEUTICAL APPLICATIONS; PHARMACEUTICAL RESEARCH; SIDE EFFECT; TARGET COMPOUND;

DRUG INTERACTIONS; ENZYME INHIBITION; ESCHERICHIA COLI; INTEGER PROGRAMMING; LINEARIZATION; METABOLISM; OPTIMIZATION;

TARGETS;

ESCHERICHIA COLI; HOMO SAPIENS;

DRUG; ENZYME INHIBITOR;

ALGORITHM; ARTICLE; BIOLOGICAL MODEL; DRUG DELIVERY SYSTEM; DRUG EFFECT; ESCHERICHIA COLI; GENETIC DATABASE; HUMAN; METABOLISM; METABOLOMICS; METHODOLOGY; PHYSIOLOGY; SYSTEMS BIOLOGY;

ALGORITHMS; DATABASES, GENETIC; DRUG DELIVERY SYSTEMS; ENZYME INHIBITORS; ESCHERICHIA COLI; HUMANS; METABOLIC NETWORKS AND PATHWAYS; METABOLOMICS; MODELS, BIOLOGICAL; PHARMACEUTICAL PREPARATIONS; SYSTEMS BIOLOGY;

EID: 71949111724     PISSN: 17518849     EISSN: None     Source Type: Journal    
DOI: 10.1049/iet-syb.2008.0166     Document Type: Article

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