Doxycycline induces apoptosis in PANC-1 pancreatic cancer cells

Anticancer Research

Volumn 29, Issue 10, 2009, Pages 3995-4003

  Son, Kyonsu ^a   Fujioka, Shuichi ^a   Iida, Tomonori ^a   Furukawa, Kenei ^a   Fujita, Tetsuji ^a   Yamada, Hisashi ^a   Chiao, Paul J ^b   Yanaga, Katsuhiko ^a  

^a JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Apoptosis; Doxycycline; Fas; IL 8; p53; Pancreatic cancer

Indexed keywords

ANGIOGENIC FACTOR; DOXYCYCLINE; FAS ANTIGEN; FAS LIGAND; INTERLEUKIN 8; PACLITAXEL; PROTEIN BCL XL; PROTEIN MCL 1; PROTEIN P21; PROTEIN P53; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DNA FRAGMENTATION; DOWN REGULATION; GENE EXPRESSION; GENE REPRESSION; HUMAN; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; NORTHERN BLOTTING; PANCREAS CANCER; PRIORITY JOURNAL; TUMOR XENOGRAFT;

ADENOCARCINOMA; ANIMALS; APOPTOSIS; CELL GROWTH PROCESSES; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DOWN-REGULATION; DOXYCYCLINE; DRUG INTERACTIONS; G1 PHASE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INTERLEUKIN-8; MICE; PACLITAXEL; PANCREATIC NEOPLASMS; S PHASE; TUMOR NECROSIS FACTOR-ALPHA; TUMOR SUPPRESSOR PROTEIN P53; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 71949099927     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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