Cutting edge: Migration of Langerhans dendritic cells is impaired in autoimmune dermatitis

Journal of Immunology

Volumn 181, Issue 11, 2009, Pages 7468-7472

  Eriksson, Anna U ^a   Singh, Ram Raj ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE DISEASE; CELL ACTIVATION; CELL AGGREGATION; CELL MIGRATION; CELLULAR IMMUNITY; CONTROLLED STUDY; DENDRITIC CELL; DERMATITIS; DISEASE SEVERITY; IMMUNOPATHOGENESIS; LANGERHANS CELL; LYMPH NODE; LYMPHATIC DRAINAGE; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; SKIN INFLAMMATION; STRAIN DIFFERENCE; T LYMPHOCYTE;

EID: 71849119015     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.181.11.7468     Document Type: Article

References (16)

1. Henri, S., D. Vremec, A. Kamath, J. Waithman, S. Williams, C. Benoist, K. Burnham, S. Saeland, E. Handman, and K. Shortman. 2001. The dendritic cell populations of mouse lymph nodes. J. Immunol. 167: 741-748. (Pubitemid 32660827)
2. Valladeau, J., V. Clair-Moninot, C. Dezutter-Dambuyant, J. J. Pin, A. Kissenpfennig, M. G. Mattei, S. Ait-Yahia, E. E. Bates, B. Malissen, F. Koch, et al. 2002. Identification of mouse langerin/CD207 in Langerhans cells and some dendritic cells of lymphoid tissues. J. Immunol. 168: 782-792. (Pubitemid 34049579)
3. + dendritic cells. J. Exp. Med. 204: 3147-3156.
4. Ruedl, C., P. Koebel, and K. Karjalainen. 2001. In vivo-matured Langerhans cells continue to take up and process native proteins unlike in vitro-matured counterparts. J. Immunol. 166: 7178-7182. (Pubitemid 32525590)
5. Merad, M., P. Hoffmann, E. Ranheim, S. Slaymaker, M. G. Manz, S. A. Lira, I. Charo, D. N. Cook, I. L. Weissman, S. Strober, and E. G. Engleman. 2004. Depletion of host Langerhans cells before transplantation of donor alloreactive T cells prevents skin graft-versus-host disease. Nat. Med. 10: 510-517. (Pubitemid 38667910)
6. Toews, G. B., P. R. Bergstresser, and J. W. Streilein. 1980. Epidermal Langerhans cell density determines whether contact hypersensitivity or unresponsiveness follows skin painting with DNFB. J. Immunol. 124: 445-453.
7. Mayerova, D., E. A. Parke, L. S. Bursch, O. A. Odumade, and K. A. Hogquist. 2004. Langerhans cells activate naive self-antigen-specific CD8 T cells in the steady state. Immunity 21: 391-400. (Pubitemid 39208340)
8. Kissenpfennig, A., S. Henri, B. Dubois, C. Laplace-Builhe, P. Perrin, N. Romani, C. H. Tripp, P. Douillard, L. Leserman, D. Kaiserlian, et al. 2005. Dynamics and function of Langerhans cells in vivo: dermal dendritic cells colonize lymph node areas distinct from slower migrating Langerhans cells. Immunity 22: 643-654. (Pubitemid 40719199)
9. Yang, J. Q., T. Chun, H. Liu, S. Hong, H. Bui, L. Van Kaer, C. R. Wang, and R. R. Singh. 2004. CD1d deficiency exacerbates inflammatory dermatitis in MRL-lpr/lpr mice. Eur. J. Immunol. 34: 1723-1732.
10. Peng, S. L., J. M. McNiff, M. P. Madaio, J. Ma, M. J. Owen, R. A. Flavell, A. C. Hayday, and J. Craft. 1997. αβ T cell regulation and CD40 ligand dependence in murine systemic autoimmunity. J. Immunol. 158: 2464-2470.
11. Cumberbatch, M., M. Singh, R. J. Dearman, H. S. Young, I. Kimber, and C. E. Griffiths. 2006. Impaired Langerhans cell migration in psoriasis. J. Exp. Med. 203: 953-960.
12. Ohl, L., M. Mohaupt, N. Czeloth, G. Hintzen, Z. Kiafard, J. Zwirner, T. Blankenstein, G. Henning, and R. Forster. 2004. CCR7 governs skin dendritic cell migration under inflammatory and steady-state conditions. Immunity 21: 279-288. (Pubitemid 39094056)
13. Angeli, V., J. Llodra, J. X. Rong, K. Satoh, S. Ishii, T. Shimizu, E. A. Fisher, and G. J. Randolph. 2004. Dyslipidemia associated with atherosclerotic disease systemically alters dendritic cell mobilization. Immunity 21: 561-574. (Pubitemid 39370511)
14. Gu, L., M. W. Johnson, and A. J. Lusis. 1999. Quantitative trait locus analysis of plasma lipoprotein levels in an autoimmune mouse model: interactions between lipoprotein metabolism, autoimmune disease, and atherogenesis. Arterioscler Thromb. Vasc. Biol. 19: 442-453. (Pubitemid 29072762)
15. Waithman, J., R. S. Allan, H. Kosaka, H. Azukizawa, K. Shortman, M. B. Lutz, W. R. Heath, F. R. Carbone, and G. T. Belz. 2007. Skin-derived dendritic cells can mediate deletional tolerance of class I-restricted self-reactive T cells. J. Immunol. 179: 4535-4541.
16. Kaplan, D. H., M. C. Jenison, S. Saeland, W. D. Shlomchik, and M. J. Shlomchik. 2005. Epidermal Langerhans cell-deficient mice develop enhanced contact hypersensitivity. Immunity 23: 611-620.