Adiponectin receptor 2 is regulated by nutritional status, leptin and pregnancy in a tissue-specific manner

Physiology and Behavior

Volumn 99, Issue 1, 2010, Pages 91-99

  González, Carmen Ruth ^a,d   Caminos, Jorge Eduardo ^a,b   Gallego, Rosalía ^a,d   Tovar, Sulay ^a,d   Vázquez, María Jesús ^a,d   Garcés, María Fernanda ^b   Lopez, Miguel ^a,d   García Caballero, Tomás ^a   Tena Sempere, Manuel ^c,d   Nogueiras, Rubén ^a,d   Diéguez, Carlos ^a,d  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^b UNIVERSIDAD NACIONAL DE COLOMBIA   (Colombia)

^c UNIVERSITY OF CÓRDOBA   (Spain)

^d Instituto de Salud Carlos III   (Spain)

Author keywords

Adiponectin; Adiponectin receptor 2; Leptin; Pregnancy

Indexed keywords

ADIPONECTIN RECEPTOR 2; LEPTIN; MESSENGER RNA;

ANIMAL TISSUE; ARTICLE; BROWN ADIPOSE TISSUE; CALORIC RESTRICTION; CHRONIC DISEASE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; LIVER; MALE; MALNUTRITION; NONHUMAN; NUCLEOTIDE SEQUENCE; NUTRITIONAL STATUS; PREGNANCY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RADIOIMMUNOASSAY; RAT; REAL TIME POLYMERASE CHAIN REACTION; STOMACH; TISSUE SPECIFICITY; WHITE ADIPOSE TISSUE;

ADIPONECTIN; ADIPOSE TISSUE; ANIMALS; CALORIC RESTRICTION; FASTING; FEMALE; GENE EXPRESSION REGULATION; LEPTIN; LIVER; MALE; NUTRITIONAL STATUS; PREGNANCY; RADIOIMMUNOASSAY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ADIPONECTIN; RNA, MESSENGER; STATISTICS, NONPARAMETRIC; STOMACH;

EID: 71849107477     PISSN: 00319384     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.physbeh.2009.10.015     Document Type: Article

References (56)

1. Maeda K., Okubo K., Shimomura I., Funahashi T., Matsuzawa Y., and Matsubara K. cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (AdiPose Most abundant Gene transcript 1). Biochem Biophys Res Commun 221 (1996) 286-289
2. Scherer P.E., Williams S., Fogliano M., Baldini G., and Lodish H.F. A novel serum protein similar to C1q, produced exclusively in adipocytes. J Biol Chem 270 (1995) 26746-26749
3. Nakano Y., Tobe T., Choi-Miura N.H., Mazda T., and Tomita M. Isolation and characterization of GBP28, a novel gelatin-binding protein purified from human plasma. J Biochem (Tokyo) 120 (1996) 803-812
4. Chabrolle C., Tosca L., and Dupont J. Regulation of adiponectin and its receptors in rat ovary by human chorionic gonadotrophin treatment and potential involvement of adiponectin in granulosa cell steroidogenesis. Reproduction 133 (2007) 719-731
5. Caminos J.E., Nogueiras R., Gaytan F., Pineda R., Gonzalez C.R., Barreiro M.L., et al. Novel expression and direct effects of adiponectin in the rat testis. Endocrinology (2008) 149:3390-402
6. Kadowaki T., Yamauchi T., Kubota N., Hara K., Ueki K., and Tobe K. Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome. J Clin Invest 116 (2006) 1784-1792
7. Scherer P.E. Adipose tissue: from lipid storage compartment to endocrine organ. Diabetes 55 (2006) 1537-1545
8. Hu E., Liang P., and Spiegelman B.M. AdipoQ is a novel adipose-specific gene dysregulated in obesity. J Biol Chem 271 (1996) 10697-10703
9. Hotta K., Funahashi T., Arita Y., Takahashi M., Matsuda M., Okamoto Y., et al. Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients. Arterioscler Thromb Vasc Biol 20 (2000) 1595-1599
10. Ouchi N., Ohishi M., Kihara S., Funahashi T., Nakamura T., Nagaretani H., et al. Association of hypoadiponectinemia with impaired vasoreactivity. Hypertension 42 (2003) 231-234
11. Weyer C., Funahashi T., Tanaka S., Hotta K., Matsuzawa Y., Pratley R.E., et al. Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia. J Clin Endocrinol Metab 86 (2001) 1930-1935
12. Yamauchi T., Kamon J., Waki H., Terauchi Y., Kubota N., Hara K., et al. The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat Med 7 (2001) 941-946
13. Yamauchi T., Kamon J., Ito Y., Tsuchida A., Yokomizo T., Kita S., et al. Cloning of adiponectin receptors that mediate antidiabetic metabolic effects. Nature 423 (2003) 762-769
14. Yamauchi T., Nio Y., Maki T., Kobayashi M., Takazawa T., Iwabu M., et al. Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions. Nat Med 13 (2007) 332-339
15. Yamauchi T., Kamon J., Minokoshi Y., Ito Y., Waki H., Uchida S., et al. Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase. Nat Med 8 (2002) 1288-1295
16. Tomas E., Tsao T.S., Saha A.K., Murrey H.E., Zhang C.C., Itani S.I., et al. Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation. Proc Natl Acad Sci U S A 99 (2002) 16309-16313
17. Bjursell M., Ahnmark A., Bohlooly Y., William-Olsson L., Rhedin M., Peng X.R., et al. Opposing effects of adiponectin receptors 1 and 2 on energy metabolism. Diabetes 56 (2007) 583-593
18. Civitarese A.E., Jenkinson C.P., Richardson D., Bajaj M., Cusi K., Kashyap S., et al. Adiponectin receptors gene expression and insulin sensitivity in non-diabetic Mexican Americans with or without a family history of Type 2 diabetes. Diabetologia 47 (2004) 816-820
19. Tan G.D., Debard C., Funahashi T., Humphreys S.M., Matsuzawa Y., Frayn K.N., et al. Changes in adiponectin receptor expression in muscle and adipose tissue of type 2 diabetic patients during rosiglitazone therapy. Diabetologia 48 (2005) 1585-1589
20. McAinch A.J., Steinberg G.R., Mollica J., O'Brien P.E., Dixon J.B., Macaulay S.L., et al. Differential regulation of adiponectin receptor gene expression by adiponectin and leptin in myotubes derived from obese and diabetic individuals. Obesity (Silver. Spring) 14 (2006) 1898-1904
21. Tsuchida A., Yamauchi T., Ito Y., Hada Y., Maki T., Takekawa S., et al. Insulin/Foxo1 pathway regulates expression levels of adiponectin receptors and adiponectin sensitivity. J Biol Chem 279 (2004) 30817-30822
22. Inukai K., Nakashima Y., Watanabe M., Takata N., Sawa T., Kurihara S., et al. Regulation of adiponectin receptor gene expression in diabetic mice. Am J Physiol Endocrinol Metab 288 (2005) E876-E882
23. Staiger H., Kaltenbach S., Staiger K., Stefan N., Fritsche A., Guirguis A., et al. Expression of adiponectin receptor mRNA in human skeletal muscle cells is related to in vivo parameters of glucose and lipid metabolism. Diabetes 53 (2004) 2195-2201
24. Kharroubi I., Rasschaert J., Eizirik D.L., and Cnop M. Expression of adiponectin receptors in pancreatic beta cells. Biochem Biophys Res Commun 312 (2003) 1118-1122
25. Winzell M.S., Nogueiras R., Dieguez C., and Ahren B. Dual action of adiponectin on insulin secretion in insulin-resistant mice. Biochem Biophys Res Commun 321 (2004) 154-160
26. Nilsson L., Binart N., Bohlooly Y., Bramnert M., Egecioglu E., Kindblom J., et al. Prolactin and growth hormone regulate adiponectin secretion and receptor expression in adipose tissue. Biochem Biophys Res Commun 331 (2005) 1120-1126
27. Fasshauer M., Klein J., Kralisch S., Klier M., Lossner U., Bluher M., et al. Growth hormone is a positive regulator of adiponectin receptor 2 in 3T3-L1 adipocytes. FEBS Lett 558 (2004) 27-32
28. Caminos J.E., Nogueiras R., Gallego R., Bravo S., Tovar S., Garcia-Caballero T., et al. Expression and regulation of adiponectin and receptor in human and rat placenta. J Clin Endocrinol Metab 90 (2005) 4276-4286
29. Legradi G., Emerson C.H., Ahima R.S., Flier J.S., and Lechan R.M. Leptin prevents fasting-induced suppression of prothyrotropin-releasing hormone messenger ribonucleic acid in neurons of the hypothalamic paraventricular nucleus. Endocrinology 138 (1997) 2569-2576
30. Gualillo O., Caminos J.E., Nogueiras R., Seoane L.M., Arvat E., Ghigo E., et al. Effect of food restriction on ghrelin in normal-cycling female rats and in pregnancy. Obes Res 10 (2002) 682-687
31. Nogueiras R., Gualillo O., Caminos J.E., Casanueva F.F., and Dieguez C. Regulation of resistin by gonadal, thyroid hormone, and nutritional status. Obes Res 11 (2003) 408-414
32. Caminos J.E., Nogueiras R., Gallego R., Bravo S., Tovar S., Garcia-Caballero T., et al. Expression and regulation of adiponectin and receptor in human and rat placenta. J Clin Endocrinol Metab 90 (2005) 4276-4286
33. Pineiro R., Iglesias M.J., Gallego R., Raghay K., Eiras S., Rubio J., et al. Adiponectin is synthesized and secreted by human and murine cardiomyocytes. FEBS Lett 579 (2005) 5163-5169
34. Caminos J.E., Bravo S.B., Garces M.F., Gonzalez C.R., Cepeda L.A., Gonzalez A.C., et al. Vaspin and amylin are expressed in human and rat placenta and regulated by nutritional status. Histol Histopathol 24 (2009) 979-990
35. Vazquez M.J., Gonzalez C.R., Varela L., Lage R., Tovar S., Sangiao-Alvarellos S., et al. Central resistin regulates hypothalamic and peripheral lipid metabolism in a nutritional dependent fashion. Endocrinology (2008) 149:4534-43
36. Gonzalez C.R., Vazquez M.J., Lopez M., and Dieguez C. Influence of chronic undernutrition and leptin on GOAT mRNA levels in rat stomach mucosa. J Mol Endocrinol 41 (2008) 415-421
37. Caminos J.E., Nogueiras R., Gallego R., Bravo S., Tovar S., Garcia-Caballero T., et al. Expression and regulation of adiponectin and receptor in human and rat placenta. J Clin Endocrinol Metab 90 (2005) 4276-4286
38. Ishikawa M., Kitayama J., Yamauchi T., Kadowaki T., Maki T., Miyato H., et al. Adiponectin inhibits the growth and peritoneal metastasis of gastric cancer through its specific membrane receptors AdipoR1 and AdipoR2. Cancer Sci 98 (2007) 1120-1127
39. Caminos J.E., Nogueiras R., Gallego R., Bravo S., Tovar S., Garcia-Caballero T., et al. Expression and regulation of adiponectin and receptor in human and rat placenta. J Clin Endocrinol Metab 90 (2005) 4276-4286
40. Caminos J.E., Nogueiras R., Gallego R., Bravo S., Tovar S., Garcia-Caballero T., et al. Expression and regulation of adiponectin and receptor in human and rat placenta. J Clin Endocrinol Metab 90 (2005) 4276-4286
41. Qi Y., Takahashi N., Hileman S.M., Patel H.R., Berg A.H., Pajvani U.B., et al. Adiponectin acts in the brain to decrease body weight. Nat Med 10 (2004) 524-529
42. Kubota N., Yano W., Kubota T., Yamauchi T., Itoh S., Kumagai H., et al. Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake. Cell Metab 6 (2007) 55-68
43. Liu Y., Michael M.D., Kash S., Bensch W.R., Monia B.P., Murray S.F., et al. Deficiency of adiponectin receptor 2 reduces diet-induced insulin resistance but promotes type 2 diabetes. Endocrinology 148 (2007) 683-692
44. Zhang Y., Matheny M., Zolotukhin S., Tumer N., and Scarpace P.J. Regulation of adiponectin and leptin gene expression in white and brown adipose tissues: influence of beta3-adrenergic agonists, retinoic acid, leptin and fasting. Biochim Biophys Acta 1584 (2002) 115-122
45. Bluher M., Fasshauer M., Kralisch S., Schon M.R., Krohn K., and Paschke R. Regulation of adiponectin receptor R1 and R2 gene expression in adipocytes of C57BL/6 mice. Biochem Biophys Res Commun 329 (2005) 1127-1132
46. Barnea M., Shamay A., Stark A.H., and Madar Z. A high-fat diet has a tissue-specific effect on adiponectin and related enzyme expression. Obesity (Silver. Spring) 14 (2006) 2145-2153
47. Beylot M., Pinteur C., and Peroni O. Expression of the adiponectin receptors AdipoR1 and AdipoR2 in lean rats and in obese Zucker rats. Metabolism 55 (2006) 396-401
48. Rasmussen M.S., Lihn A.S., Pedersen S.B., Bruun J.M., Rasmussen M., and Richelsen B. Adiponectin receptors in human adipose tissue: effects of obesity, weight loss, and fat depots. Obesity (Silver. Spring) 14 (2006) 28-35
49. Woodall S.M., Breier B.H., Johnston B.M., and Gluckman P.D. A model of intrauterine growth retardation caused by chronic maternal undernutrition in the rat: effects on the somatotrophic axis and postnatal growth. J Endocrinol 150 (1996) 231-242
50. Friedman J.E., Dohm G.L., Leggett-Frazier N., Elton C.W., Tapscott E.B., Pories W.P., et al. Restoration of insulin responsiveness in skeletal muscle of morbidly obese patients after weight loss. Effect on muscle glucose transport and glucose transporter GLUT4. J Clin Invest 89 (1992) 701-705
51. Weiss E.P., and Holloszy J.O. Improvements in body composition, glucose tolerance, and insulin action induced by increasing energy expenditure or decreasing energy intake. J Nutr 137 (2007) 1087-1090
52. Sutter-Dub M.T., Sfaxi A., and Strozza P. Glucose metabolism in the female rat adipocyte: lipid synthesis from glucose during pregnancy and progesterone treatment. J Endocrinol 97 (1983) 207-212
53. Tamas G., and Kerenyi Z. Gestational diabetes: current aspects on pathogenesis and treatment. Exp Clin Endocrinol Diabetes 109 Suppl 2 (2001) S400-S411
54. Chien E.K., Hara M., Rouard M., Yano H., Phillippe M., Polonsky K.S., et al. Increase in serum leptin and uterine leptin receptor messenger RNA levels during pregnancy in rats. Biochem Biophys Res Commun 237 (1997) 476-480
55. Pucci E., Chiovato L., and Pinchera A. Thyroid and lipid metabolism. Int J Obes Relat Metab Disord 24 Suppl 2 (2000) S109-S112
56. Pujol E., Proenza A.M., Roca P., and Llado I. Changes in mammary fat pad composition and lipolytic capacity throughout pregnancy. Cell Tissue Res 323 (2006) 505-511