Changes in mammary fat pad composition and lipolytic capacity throughout pregnancy

Cell and Tissue Research

Volumn 323, Issue 3, 2006, Pages 505-511

  Pujol, Esperanza ^a   Proenza, Ana M ^a   Roca, Pilar ^a   Lladó, Isabel ^a  

^a UNIVERSITAT DE LES ILLES BALEARS   (Spain)

Author keywords

Adipocyte; Lipolytic pathway; Lipoprotein lipase; Mammary gland; Pregnancy; Rat (Wistar)

Indexed keywords

ADENYLATE CYCLASE; ALPHA 2 ADRENERGIC RECEPTOR; BETA 3 ADRENERGIC RECEPTOR; CYCLIC AMP DEPENDENT PROTEIN KINASE; FAT; HORMONE SENSITIVE LIPASE; LIPOPROTEIN LIPASE; PROTEIN; TRIACYLGLYCEROL;

ADIPOCYTE; ANIMAL TISSUE; ARTICLE; BREAST CELL; CONTROLLED STUDY; DNA CONTENT; FEMALE; LIPID STORAGE; LIPOLYSIS; MAMMARY GLAND; MORPHOLOGY; NONHUMAN; PREGNANCY; PRIORITY JOURNAL; RAT;

ADENYLATE CYCLASE; ADIPOCYTES; ADIPOSE TISSUE; ANIMALS; BODY WEIGHT; CHOLESTEROL ESTERASE; CYCLIC AMP-DEPENDENT PROTEIN KINASES; FEMALE; LIPOLYSIS; LIPOPROTEIN LIPASE; MAMMARY GLANDS, ANIMAL; PREGNANCY; PREGNANCY, ANIMAL; RATS; RATS, WISTAR; RECEPTORS, ADRENERGIC; STEROL ESTERASE;

ANIMALIA;

EID: 32444435669     PISSN: 0302766X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00441-005-0085-0     Document Type: Article

References (39)

1. Abell CW, Monahan TM (1973) The role of adenosine 3′,5′- cyclic monophosphate in the regulation of mammalian cell division. J Cell Biol 59:549-558
2. Arner P (1995) Differences in lipolysis between human subcutaneous and omental adipose tissues. Ann Med 27:435-438
3. Bandyopadhyay GK, Lee LY, Guzman RC, Nandi S (1995) Effect of reproductive states on lipid mobilization and linoleic acid metabolism in mammary glands. Lipids 30:155-162
4. Carey GB (1998) Mechanisms regulating adipocyte lipolysis. Adv Exp Med Biol 441:157-170
5. Carrascosa JM, Ramos P, Molero JC, Herrera E (1998) Changes in the kinase activity of the insulin receptor account for an increased insulin sensitivity of mammary gland in late pregnancy. Endocrinology 139:520-526
6. Chin KV, Yang WL, Ravatn R, Kita T, Reitman E, Vettori D, Cvijic ME, Shin M, Iacono L (2002) Reinventing the wheel of cyclic AMP: novel mechanisms of cAMP signaling. Ann N Y Acad Sci 968:49-64
7. Eckel RH (1989) Lipoprotein lipase. A multifunctional enzyme relevant to common metabolic diseases. N Engl J Med 320:1060-1068
8. Engfeldt P, Hellmer J, Wahrenberg H, Arner P (1988) Effects of insulin on adrenoceptor binding and the rate of catecholamine-induced lipolysis in isolated human fat cells. J Biol Chem 263:15553-15560
9. Feve B, Elhadri K, Quignard-Boulange A, Pairault J (1994) Transcriptional down-regulation by insulin of the beta 3-adrenergic receptor expression in 3T3-F442A adipocytes: a mechanism for repressing the cAMP signaling pathway. Proc Natl Acad Sci USA 91:5677-5681
10. Hadri KE, Charon C, Pairault J, Hauguel-De Mouzon S, Quignard-Boulange A, Feve B (1997) Down-regulation of beta3-adrenergic receptor expression in rat adipose tissue during the fasted/fed transition: evidence for a role of insulin. Biochem J 323:359-364
11. Hausman GJ (1982) Adipocyte development in subcutaneous tissues of the young rat. Acta Anat (Basel) 112:185-196
12. Hovey RC, McFadden TB, Akers RM (1999) Regulation of mammary gland growth and morphogenesis by the mammary fat pad: a species comparison. J Mammary Gland Biol Neoplasia 4:53-68
13. Jensen MD (1997) Lipolysis: contribution from regional fat. Annu Rev Nutr 17:127-139
14. Kraemer FB, Patel S, Saedi MS, Sztalryd C (1993) Detection of hormone-sensitive lipase in various tissues. I. Expression of an HSL/bacterial fusion protein and generation of anti-HSL antibodies. J Lipid Res 34:663-671
15. Laemmli UK (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685
16. Lafontan M, Berlan M (1993) Fat cell adrenergic receptors and the control of white and brown fat cell function. J Lipid Res 34:1057-1091
17. Langin D, Portillo M, Dauzats M, Lafontan M (1992) Drop in the "atypical" beta-adrenergic response and modification of the beta/alpha 2-adrenoceptor balance in fat cells from aging rabbits. Endocrinology 130:307-315
18. Llado I, Pons A, Palou A (1999) Effects of fasting on lipoprotein lipase activity in different depots of white and brown adipose tissues in diet-induced overweight rats. J Nutr Biochem 10:609-614
19. Lopez-Luna P, Maier I, Herrera E (1991) Carcass and tissue fat content in the pregnant rat. Biol Neonate 60:29-38
20. Lowry O, Rosebrough N, Farr A, Randall R (1951) Protein measurement with the Folin phenol reagent. J Biol Chem 193:265-275
21. Martin-Hidalgo A, Holm C, Belfrage P, Schotz MC, Herrera E (1994) Lipoprotein lipase and hormone-sensitive lipase activity and mRNA in rat adipose tissue during pregnancy. Am J Physiol 266:E930-E935
22. Martin-Hidalgo A, Huerta L, Alvarez N, Alegria G, Toledo MD, Herrera E (2005) Expression, activity, and cellular localization of hormone-sensitive lipase in rat mammary gland during pregnancy and lactation. J Lipid Res 46:658-668
23. Masso-Welch PA, Darcy KM, Stangle-Castor NC, Ip MM (2000) A developmental atlas of rat mammary gland histology. J Mammary Gland Biol Neoplasia 5:165-185
24. Mead JR, Irvine SA, Ramji DP (2002) Lipoprotein lipase: structure, function, regulation, and role in disease. J Mol Med 80:753-769
25. Morroni M, Giordano A, Zingaretti MC, Boiani R, De Matteis R, Kahn BB, Nisoli E, Tonello C, Pisoschi C, Luchetti MM, Marelli M, Cinti S (2004) Reversible transdifferentiation of secretory epithelial cells into adipocytes in the mammary gland. Proc Natl Acad Sci USA 101:16801-16806
26. Munoz A, Lavandero S, Donoso E, Puente J, Sapag-Hagar M (1985) A role for adrenaline and calmodulin in modulating cyclic AMP levels during the lactogenic cycle. FEBS Lett 187:173-176
27. Neville MC, Medina D, Monks J, Hovey RC (1998) The mammary fat pad. J Mammary Gland Biol Neoplasia 3:109-116
28. Pastan I, Perlman RL (1972) Regulation of gene transcription in Escherichia coli by cyclic AMP. Adv Cyclic Nucleotide Res 1:11-16
29. Perry JW, Oka T (1980) Cyclic AMP as a negative regulator of hormonally induced lactogenesis in mouse mammary gland organ culture. Proc Natl Acad Sci USA 77:2093-2097
30. Pond CM, Mattacks CA (1991) The effects of noradrenaline and insulin on lipolysis in adipocytes isolated from nine different adipose depots of guinea-pigs. Int J Obes 15:609-618
31. Puigserver P, Llado I, Palou A, Gianotti M (1991) Evidence for masking of brown adipose tissue mitochondrial GDP-binding sites in response to fasting in rats made obese by dietary manipulation. Effects of reversion to standard diet. Biochem J 279:575-579
32. Pujol E, Rodriguez-Cuenca S, Frontera M, Justo R, Llado I, Kraemer FB, Gianotti M, Roca P (2003) Gender and site-related effects on lipolytic capacity of rat white adipose tissue. Cell Mol Life Sci 60:1982-1989
33. Ramos P, Herrera E (1996) Comparative responsiveness to prolonged hyperinsulinemia between adipose-tissue and mammary-gland lipoprotein lipase activities in pregnant rats. Early Pregnancy 2:29-35
34. Ramos P, Martin-Hidalgo A, Herrera E (1999) Insulin-induced upregulation of lipoprotein lipase messenger ribonucleic acid and activity in mammary gland. Endocrinology 140:1089-1093
35. Rijnkels M, Rosen JM (2001) Adenovirus-Cre-mediated recombination in mammary epithelial early progenitor cells. J Cell Sci 114:3147-3153
36. Rillema JA (1976) Cyclic nucleotides, adenylate cyclase, and cyclic AMP phosphodiesterase in mammary glands from pregnant and lactating mice. Proc Soc Exp Biol Med 151:748-751
37. Rudolph MC, McManaman JL, Hunter L, Phang T, Neville MC (2003) Functional development of the mammary gland: use of expression profiling and trajectory clustering to reveal changes in gene expression during pregnancy, lactation, and involution. J Mammary Gland Biol Neoplasia 8:287-307
38. Smith GH, Medina D (1988) A morphologically distinct candidate for an epithelial stem cell in mouse mammary gland. J Cell Sci 90:173-183
39. Thomas PS, Farquhar MN (1978) Specific measurement of DNA in nuclei and nucleic acids using diaminobenzoic acid. Anal Biochem 89:35-44