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Pax 6: mastering eye morphogenesis and eye evolution
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Pax6 and eyeless are orthologous master genes for eye morphogenesis in mouse and Drosophila, respectively. Pax3 when ectopically transferred to the fly is indeed capable of developing a functional eye, although a fly eye and not a mouse one.
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Gehring W.J., and Ikeo K. Pax 6: mastering eye morphogenesis and eye evolution. Trends Genet 15 (1999) 371-377. Pax6 and eyeless are orthologous master genes for eye morphogenesis in mouse and Drosophila, respectively. Pax3 when ectopically transferred to the fly is indeed capable of developing a functional eye, although a fly eye and not a mouse one.
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(1999)
Trends Genet
, vol.15
, pp. 371-377
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Gehring, W.J.1
Ikeo, K.2
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