Hepatocyte growth factor induced up-regulations of VEGF through Egr-1 in hepatocellular carcinoma cells

Clinical and Experimental Metastasis

Volumn 26, Issue 7, 2009, Pages 685-692

  Lee, Kyung Hee ^a   Kim, Jae Ryong ^a  

^a Yeungnam University College of Medicine   (South Korea)

Author keywords

Angiogenesis; Egr 1; HGF; IL 8; VEGF

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ANGIOGENIC FACTOR; INTERLEUKIN 8; LUCIFERASE; SCATTER FACTOR; TRANSCRIPTION FACTOR EGR 1; VASCULOTROPIN;

ANGIOGENESIS; ARTICLE; CANCER CELL CULTURE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DNA MICROARRAY; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; NUCLEOTIDE SEQUENCE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

BASE SEQUENCE; BLOTTING, WESTERN; CARCINOMA, HEPATOCELLULAR; CHROMATIN IMMUNOPRECIPITATION; DNA PRIMERS; EARLY GROWTH RESPONSE PROTEIN 1; GENE KNOCKDOWN TECHNIQUES; HEPATOCYTE GROWTH FACTOR; HUMANS; INTERLEUKIN-8; LIVER NEOPLASMS; MOLECULAR SEQUENCE DATA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TUMOR CELLS, CULTURED; UP-REGULATION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 71849091928     PISSN: 02620898     EISSN: 15737276     Source Type: Journal    
DOI: 10.1007/s10585-009-9266-7     Document Type: Article

References (28)

1. M Jeffers S Rong GF Vande 1996 Enhanced tumorigenicity and invasion-metastasis by hepatocyte growth factor/scatter factor-met signaling in human cells concomitant with induction of the urokinase proteolysis network Mol Cell Biol 16 1115 1125 1:CAS:528:DyaK28XhtFOls7k%3D 8622656
2. PM Comoglio C Boccaccio 2001 Scatter factors and invasive growth Semin Cancer Biol 11 153 165 10.1006/scbi.2000.0366 10.1006/scbi.2000.0366 1:CAS:528:DC%2BD3MXivFGgsr0%3D 11322834 (Pubitemid 32423290)
3. P Vejchapipat P Tangkijvanich A Theamboonlers V Chongsrisawat S Chittmittrapap Y Poovorawan 2004 Association between serum hepatocyte growth factor and survival in untreated hepatocellular carcinoma J Gastroenterol 39 1182 1188 10.1007/s00535-004-1469-8 10.1007/s00535-004-1469-8 1:CAS:528:DC%2BD2MXhtFSrtA%3D%3D 15622483 (Pubitemid 40074285)
4. W Brian PY Xin LL Tin B Lorena TY Ning GC Joshua VW Carter C Zhong 2005 Hepatocyte growth factor/scatter factor differentially regulates expression of proangiogenic factors through Egr-1 in head and neck squamous cell carcinoma Cancer Res 65 16 7071 7080 10.1158/0008-5472.CAN-04-0989 10.1158/0008-5472.CAN- 04-0989 (Pubitemid 41161234)
5. S Ninck C Reisser G Dyckhoff B Helmke H Bauer C Herold-Mende 2003 Expression profiles of angiogenic growth factors in squamous cell carcinomas of the head and neck Int J Cancer 106 34 44 10.1002/ijc.11188 10.1002/ijc.11188 1:CAS:528:DC%2BD3sXltFent7g%3D 12794754 (Pubitemid 36750385)
6. F Riedel K Gotte J Schwalb H Wirtz W Bergler K Hormann 2000 Serum levels off vascular endothelial growth factor in patients with head and neck cancer Eur Arch Otorhinolaryngol 257 332 336 10.1007/s004059900208 10.1007/s004059900208 1:STN:280:DC%2BD3cvktlCltg%3D%3D 10993554
7. G Dong Z Chen ZY Li NT Yeh CC Bancroft WC Van 2001 Hepatocyte growth factor/scatter factor-induced activation of MEK and PI3 K signal pathways contributes to expression of proangiogenic cytokines interleukin-8 and vascular endothelial growth factor in head and neck squamous cell carcinoma Cancer Res 61 5911 5918 1:CAS:528:DC%2BD3MXlvVCgu70%3D 11479233
8. YW Zhang Y Su OV Volpert GF Vande Woude 2003 Hepatocyte growth factor/scatter factor mediates angiogenesis through positive VEGF and negative thrombospondin 1 regulation Proc Natl Acad Sci USA 100 12718 12723 10.1073/pnas.2135113100 10.1073/pnas.2135113100 1:CAS:528:DC%2BD3sXoslKntL8%3D 14555767 (Pubitemid 37339965)
9. CC Bancroft Z Chen J Yeh, et al. 2002 Effects of pharmacologic antagonists of epidermal growth factor receptor, PI3 K and MEK signal kinases on NF-kB and AP-1 activation and IL-8 and VEGF expression in human head and neck squamous cell carcinoma lines Int J Cancer 99 538 548 10.1002/ijc.10398 10.1002/ijc.10398 1:CAS:528:DC%2BD38XjsFansLw%3D 11992543 (Pubitemid 34461606)
10. CC Bancroft Z Chen G Dong, et al. 2001 Coexpression of proangiogenic factors IL-8 and VEGF by human head and neck squamous cell carcinoma involves coactivation by MEK-MAPK and IKK-NF-kB signal pathways Clin Cancer Res 7 435 442 1:CAS:528:DC%2BD3MXhvFKntrs%3D 11234901
11. VP Sukhatme X Cao LC Chang C-H Tsai-Morris D Stamenkovich PCP Ferreira DR Cohen SA Edwards TB Shows T Curran MM Le Beau ED Adamson 1988 A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization Cell 53 37 43 10.1016/0092-8674(88)90485-0 10.1016/0092-8674(88)90485-0 1:CAS:528:DyaL1cXls1Cmtbo%3D 3127059
12. P Chavrier M Zerial P Lemaire J Almendral R Bravo P Charnay 1988 A gene encoding a protein with zinc fingers is activated during G0/G1 transition in cultured cells EMBO J 7 29 35 1:CAS:528:DyaL1cXovVyqtQ%3D%3D 3129290
13. SJ Baek JS Kim SM Moore SH Lee J Martinez TE Eling 2005 Cyclooxygenase inhibitors induce the expression of the tumor suppressor gene EGR-1, which results in the up-regulation of NAG-1, an antitumorigenic protein Mol Pharmacol 67 356 364 10.1124/mol.104.005108 10.1124/mol.104.005108 1:CAS:528: DC%2BD2MXhtVWrs7s%3D 15509713 (Pubitemid 40216727)
14. RG Fahmy CR Dass LQ Sun CN Chesterman LM Khachigian 2003 Transcription Factor Egr-1 supports FGF-dependent angiogenesis during neovascularization and tumor growth Nat Med 9 1026 1032 10.1038/nm905 10.1038/nm905 1:CAS:528:DC%2BD3sXlvV2isr4%3D 12872165 (Pubitemid 37021782)
15. SH Yang JS Kim TJ Oh MS Kim SW Lee SK Woo HS Cho YH Choi YH Kim SY Rha HC Chung SW An 2003 Genome-scale analysis of resveratrol-induced gene expression profile in human ovarian cancer cells using a cDNA microarray Int J Oncol 22 741 750 1:CAS:528:DC%2BD3sXislWhs7c%3D 12632063
16. HL Kyung YC Eun KK Min IJ Byung NK Tae WK Sang KS Sun HK Jung RK Jae 2006 Regulation of hepatocyte growth factor-mediated urokinase plasminogen activator secretion by MEK/ERK activation in human stomach cancer cell lines Exp Mol Med 38 1 27 35
17. Schug J, Overton GC (1977) TESS: transcription element search software. Technical Report CBIL-TR-1997-1001-v0.0 of the Computational Biology and Informatics Laboratory, School of Medicine, University of Pennsylania
18. F Bussolino MF Di Renzo M Ziche E Bocchietto M Olivero L Naldini G Gaudino L Tamagnone A Coffer PM Comoglio 1992 Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth J Cell Biol 119 629 641 10.1083/jcb.119.3.629 10.1083/jcb.119.3.629 1:CAS:528:DyaK38XmtlWru78%3D 1383237
19. DS Grant HK Kleinman ID Goldberg MM Bhargava BJ Nickoloff JL Kinsella P Polverini EM Rosen 1993 Scatter factor induces blood vessel formation in vivo Proc Natl Acad Sci USA 90 1937 1941 10.1073/pnas.90.5.1937 10.1073/pnas.90.5. 1937 1:CAS:528:DyaK3sXitVGqt7o%3D 7680481
20. RW Lim BC Varnum HR Herschman 1987 Cloning of tetradecanoyl phorbol ester-induced 'primary response' sequences and their expression in density-arrested Swiss 3T3 cells and a TPA non-proliferative variant Oncogene 1 3 263 270 1:CAS:528:DyaL1cXhslWitw%3D%3D 3330774
21. XM Cao RA Koski A Gashler, et al. 1990 Identification and characterization of the Egr-1 gene product, a DNA-binding zinc finger protein induced by differentiation and growth signals Mol Cell Biol 10 1931 1939 1:CAS:528:DyaK3cXkslehtrs%3D 2109185
22. P Herrlich H Morrison J Sleeman V Orian-Rousseau H Konin S Weg-Remers H Ponta 2000 CD44 acts both as a growth-and invasiveness-promoting molecule and as a tumor-suppressing cofactor Ann N Y Acad Sci 910 106 120 1:CAS:528: DC%2BD3cXlsVOjtrc%3D 10911909
23. AH Hyun L Gu JK Hee GK Yonh HB Sung LL Jae HL Kyung SK Dong 2003 Overexpression of c-Met protein in gastric cancer and role of uPAR as a therapeutic target Cancer Res Treat 35 1 9 15
24. AR Juan M Glenn 2003 Hepatocyte growth factor/scatter factor induces feedback up-regulation of CD44v6 in melanoma cells through Egr-1 Cancer Res 63 1576 1582
25. E Tolnay C Kuhnen T Wiethege JE Konig B Voss KM Mmuller 1998 Hepatocyte growth factor/scatter factor and its receptor c-met are overexpressed and associated with an increased microvessel density in malignant pleural mesothelioma J Cancer Res Clin Oncol 124 291 296 10.1007/s004320050171 10.1007/s004320050171 1:CAS:528:DyaK1cXlslOjur0%3D 9692834 (Pubitemid 28332909)
26. NO Schmidt M Westphal C Hagel S Ergun D Stavrou EM Rosen K Lamszus 1999 Levels of vascular endothelial growth factor, hepatocyte growth factor/scatter factor and vasic fibroblast growth factor in human gliomas and their relation to angiogenesis Int J Cancer 84 10 18 10.1002/(SICI)1097-0215(19990219)84:1<10: :AID-IJC3>3.0.CO;2-L 10.1002/(SICI)1097-0215(19990219)84:1<10::AID- IJC3>3.0.CO;2-L 1:CAS:528:DyaK1MXht1Cqt78%3D 9988225 (Pubitemid 29059101)
27. LM Khachigian V Lindner AJ Williams T Collins 1996 Egr-1 induced endothelial gene expression: a common theme in vascular injury Science 271 1427 1431 10.1126/science.271.5254.1427 10.1126/science.271.5254.1427 1:CAS:528:DyaK28XhsFegtbY%3D 8596917
28. ES Silverman LM Khachigian V Lindner AJ Williams T Collins 1997 Inducible PDGF A-chain transcription in smooth muscle cells is mediated by Egr-1 displacement of Sp1 and Sp3 Am J Physiol 273 H1415 H1426 1:CAS:528: DyaK2sXmtlektLY%3D 9321833