Efficient synthesis of nevirapine analogs to study its metabolic profile by click fishing

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 21, 2009, Pages 6127-6130

  Bernard, Sylvain ^a   Defoy, Daniel ^a   Dory, Yves L ^a   Klarskov, Klaus ^a  

^a UNIVERSITÉ DE SHERBROOKE   (Canada)

Author keywords

5 Exo dig cyclization; Click coupling; Nevirapine; Synthesis

Indexed keywords

ANTIVIRUS AGENT; AZIDE; NEVIRAPINE; NEVIRAPINE PROPARGYL DERIVATIVE; UNCLASSIFIED DRUG;

ADDITION REACTION; ARTICLE; BIOTRANSFORMATION; CHEMISTRY; CLICK CHEMISTRY; CONTROLLED STUDY; CYCLIZATION; DRUG ERUPTION; DRUG STRUCTURE; DRUG SYNTHESIS; STEREOCHEMISTRY; SUBSTITUTION REACTION;

ANIMALS; ANTI-HIV AGENTS; CRYSTALLOGRAPHY, X-RAY; CYCLIZATION; HUMANS; MOLECULAR CONFORMATION; NEVIRAPINE; RATS;

EID: 71749097837     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.09.011     Document Type: Article

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