Enhanced adhesion of early endothelial progenitor cells to radiation-induced senescence-like vascular endothelial cells in vitro

Journal of Radiation Research

Volumn 50, Issue 5, 2009, Pages 469-475

  Sermsathanasawadi, Nuttawut ^a   Ishii, Hideto ^a   Igarashi, Kaori ^a   Miura, Masahiko ^a   Yoshida, Masayuki ^a   Inoue, Yoshinori ^a   Iwai, Takehisa ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

Early Endothelial progenitor cells; Ionizing radiation; Neovascularization; Senescence like phenotype; Vascular endothelial cells

Indexed keywords

ADHESION; CYTOLOGY; ENDOTHELIAL CELLS; MONOCLONAL ANTIBODIES; RADIATION EFFECTS; RADIATION SHIELDING; TUMORS;

EARLY ENDOTHELIAL PROGENITOR CELL; ENDOTHELIAL PROGENITOR CELLS; ENDOTHELIAL-CELLS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; IN-VITRO; NEO-VASCULARIZATION; RADIATION-INDUCED; SELECTINS; SENESCENCE-LIKE PHENOTYPE; VASCULAR ENDOTHELIAL CELLS;

IONIZING RADIATION;

ANIMALIA;

CELL ADHESION MOLECULE;

ARTICLE; CELL ADHESION; CELL AGING; CELL CULTURE; CYTOLOGY; ENDOTHELIUM CELL; HUMAN; MESENCHYMAL STEM CELL; METABOLISM; PHYSIOLOGY; RADIATION EXPOSURE;

CELL ADHESION; CELL ADHESION MOLECULES; CELL AGING; CELLS, CULTURED; ENDOTHELIAL CELLS; HUMANS; MESENCHYMAL STEM CELLS;

EID: 71749095734     PISSN: 04493060     EISSN: 13499157     Source Type: Journal    
DOI: 10.1269/jrr.09036     Document Type: Article

References (46)

1. Mao, X. W. (2006) A quantitative study of the effects of ionizing radiation on endothelial cells and capillary-like network formation. Technol. Cancer Res. Treat. 5: 127-134.
2. Karnabatidis, D., Dimopoulos, J. C., Siablis, D., Papazafiropoulos, D., Kalogeropoulou, C. P. and Nikiforidis, G. (2001) Quantification of the ionising radiation effect over angiogenesis in the chick embryo and its chorioallantoic membrane by computerised analysis of angiographic images. Acta. Radiol. 42: 333-338.
3. Sonveaux, P., Brouet, A., Havaux, X., Gregoire, V., Dessy, C., Balligand, J. L. and Feron, O. (2003) Irradiation-induced angiogenesis through the up-regulation of the nitric oxide pathway: implications for tumor radiotherapy. Cancer Res. 63: 1012-1019.
4. Kermani, P., Leclerc, G., Martel, R. and Fareh, J. (2001) Effect of ionizing radiation on thymidine uptake, differentiation, and VEGFR2 receptor expression in endothelial cells: he role of VEGF(165). Int. J. Radiat. Oncol. Biol. Phys. 50: 13-220.
5. Wachsberger, P., Burd, R. and Dicker, A. P. (2003) Tumor response to ionizing radiation combined with antiangiogenesis or vascular targeting agents: exploring mechanisms of interaction. Clin. Cancer Res. 9: 1957-1971.
6. Garcia-Barros, M., Paris, F., Cordon-Cardo, C., Lyden, D., Rafii, S., Haimovitz-Friedman, A., Fuks, Z. and Kolesnick, R. (2003) Tumor response to radiotherapy regulated by endothelial cell apoptosis. Science 300: 1155-1159.
7. Gorski, D. H., Beckett, M. A., Jaskowiak, N. T., Calvin, D. P., Mauceri, H. J., Salloum, R. M., Seetharam, S., Koons, A., Hari, D. M., Kufe, D. W. and Weichselbaum, R. R. (1999) Blockage of the vascular endothelial growth factor stress response increases the antitumor effects of ionizing radiation. Cancer Res. 59: 3374-3378.
8. Igarashi, K., Sakimoto, I., Kataoka, K., Ohta, K. and Miura, M. (2007) Radiation-induced senescence-like phenotype in proliferating and plateau-phase vascular endothelial cells. Exp Cell Res. 313: 3326-3336.
9. Ahn, G. O., Brown, J. M., Carmeliet, P. and Luttun, A. (2009) Role of endothelial progenitors and other bone marrow-derived cells in the development of the tumor vasculature. The emerging role of the bone marrow-derived stem cells in (therapeutic) angiogenesis. Angiogenesis 86: 289-297.
10. Ribatti, D. (2004) The involvement of endothelial progenitor cells in tumor angiogenesis. J. Cell Mol. Med. 8: 294-300.
11. Vajkoczy, P., Blum, S., Lamparter, M., Mailhammer, R., Erber, R., Engelhardt, B., Vestweber, D. and Hatzopoulos, A. K. (2003) Multistep nature of microvascular recruitment of ex vivo-expanded embryonic endothelial progenitor cells during tumor angiogenesis. J. Exp. Med. 197: 1755-1765.
12. Asahara, T., Murohara, T., Sullivan, A., Silver, M., van der Zee, R., Li, T., Witzenbichler, B., Schatteman, G. and Isner, J. M. (1997) Isolation of putative progenitor endothelial cells for angiogenesis. Science 275: 964-967.
13. Asahara, T. and Kawamoto, A. (2004) Endothelial progenitor cells for postnatal vasculogenesis. Am. J. Physiol. Cell Physiol. 287: C572-C579.
14. Kawamoto, A., Asahara, T. and Losordo, D. W. (2002) Transplantation of endothelial progenitor cells for therapeutic neovascularization. Cardiovasc Radiat. Med. 3-3-4: 221-225.
15. Nishiwaki, Y., Yoshida, M., Iwaguro, H., Masuda, H., Nitta, N., Asahara, T. and Isobe, M. (2007) Endothelial E-selectin potentiates neovascularization via endothelial progenitor cell-dependent and -independent mechanisms. Arterioscler Thromb Vasc Biol. 27: 512-518.
16. Jevon, M., Dorling, A. and Hornick, P. I. (2008) Progenitor cells and vascular disease. Cell Prolif. 41: 146-164.
17. Ward, M. R., Stewart, D. J. and Kutryk, M. J. (2007) Endothelial progenitor cell therapy for the treatment of coronary disease, acute MI, and pulmonary arterial hypertension: Current perspectives. Catheter Cardiovasc Interv. 70: 983-998.
18. Urbich, C. and Dimmeler, S. (2004) Endothelial progenitor cells: characterization and role in vascular biology. Circ. Res. 95: 343-353.
19. Mukai, N., Akahori, T., Komaki, M., Li, Q., Kanayasu-Toyoda, T., Ishii-Watabe, A., Kobayashi, A., Yamaguchi, T., Abe, M., Amagasa, T. and Morita, I. (2008) A comparison of the tube forming potentials of early and late endothelial progenitor cells. Exp. Cell Res. 314: 430-440.
20. Krenning, G., van Luyn, M. J. and Harmsen, M. C. (2009) Endothelial progenitor cell-based neovascularization: implications for therapy. Trends Mol. Med. 15: 180-189.
21. Yoder, M. C., Mead, L. E., Prater, D., Krier, T. R., Mroueh, K. N., Li, F., Krasich, R., Temm, C. J., Prchal, J. T. and Ingram, D. A. (2007) Redefining endothelial progenitor cells via clonal analysis and hematopoietic stem/progenitor cell principals. Blood 109: 1801-1809.
22. Hur, J., Yoon, C. H., Kim, H. S., Choi, J. H., Kang, H. J., Hwang, K. K., Oh, B. H., Lee, M. M. and Park, Y. B. (2004) Characterization of two types of endothelial progenitor cells and their different contributions to neovasculogenesis. Arterioscler Thromb Vasc Biol. 24: 288-293.
23. Ingram, D. A., Mead, L. E., Tanaka, H., Meade, V., Fenoglio, A., Mortell, K., Pollok, K., Ferkowicz, M. J., Gilley, D. and Yoder, M. C. (2004) Identification of a novel hierarchy of endothelial progenitor cells using human peripheral and umbilical cord blood. Blood 104: 2752-2760.
24. Yoon, C. H., Hur, J., Park, K. W., Kim, J. H., Lee, C. S., Oh, I. Y., Kim, T. Y., Cho, H. J., Kang, H. J., Chae, I. H., Yang, H. K., Oh, B. H., Park, Y. B. and Kim, H. S. (2005) Synergistic neovascularization by mixed transplantation of early endothelial progenitor cells and late outgrowth endothelial cells: the role of angiogenic cytokines and matrix metalloproteinases. Circulation 112: 1618-1627.
25. Nagano, M., Yamashita, T., Hamada, H., Ohneda, K., Kimura, K., Nakagawa, T., Shibuya, M., Yoshikawa, H. and Ohneda, O. (2007) Identification of functional endothelial progenitor cells suitable for the treatment of ischemic tissue using human umbilical cord blood. Blood 110: 151-160.
26. Werner, N., Junk, S., Laufs, U., Link, A., Walenta, K., Bohm, M. and Nickenig, G. (2003) Intravenous transfusion of endothelial progenitor cells reduces neointima formation after vascular injury. Circ. Res. 93: e17-e24.
27. Li, B., Sharpe, E. E., Maupin, A. B., Teleron, A. A., Pyle, A. L., Carmeliet, P. and Young, P. P. (2006) VEGF and PlGF promote adult vasculogenesis by enhancing EPC recruitment and vessel formation at the site of tumor neovascularization. Faseb J. 20: 1495-1497.
28. Sakimoto, I., Ohta, K., Yamazaki, T., Ohtani, S., Sahara, H., Sugawara, F., Sakaguchi, K. and Miura, M. (2006) Alpha-sulfoquinovosylmonoacylglycerol is a novel potent radiosensitizer targeting tumor angiogenesis. Cancer Res. 66: 2287-2295.
29. Yoshida, M., Westlin, W. F., Wang, N., Ingber, D. E., Rosenzweig, A., Resnick, N. and Gimbrone, M. A. Jr. (1996) Leukocyte adhesion to vascular endothelium induces E-selectin linkage to the actin cytoskeleton. J. Cell Biol. 133: 445-455.
30. Hill, J. M., Zalos, G., Halcox, J. P., Schenke, W. H., Waclawiw, M. A., Quyyumi, A. A. and Finkel, T. (2003) Circulating endothelial progenitor cells, vascular function, and cardiovascular risk. N. Engl. J. Med. 348: 593-600.
31. Kiely, J. M., Luscinskas, F. W. and Gimbrone M. A. Jr. (1999) Leukocyte-endothelial monolayer adhesion assay (static conditions). Methods Mol. Biol. 96: 131-136.
32. Luscinskas, F. W., Cybulsky, M. I., Kiely, J. M., Peckins, C. S., Davis, V. M. and Gimbrone, M. A. Jr. (1991) Cytokine-activated human endothelial monolayers support enhanced neutrophil transmigration via a mechanism involving both endothelial-leukocyte adhesion molecule-1 and intercellular adhesion molecule-1. J. Immunol. 146: 1617-1625.
33. Gerszten, R. E., Lim, Y. C., Ding, H. T., Snapp, K., Kansas, G., Dichek, D. A., Cabanas, C., Sanchez-Madrid, F., Gimbrone, M. A. Jr., Rosenzweig, A. and Luscinskas F. W. (1998) Adhesion of monocytes to vascular cell adhesion molecule-1-transduced human endothelial cells: implications for atherogenesis. Circ. Res. 82: 871-878.
34. Popa, E. R., Harmsen, M. C., Tio, R. A., van der Strate, B. W., Brouwer, L. A., Schipper, M., Koerts, J., De Jongste, M. J., Hazenberg, A., Hendriks, M. and van Luyn, M. J. (2006) Circulating CD34+ progenitor cells modulate host angiogenesis and inflammation in vivo. J. Mol. Cell Cardiol. 41: 86-96.
35. Voermans, C., Rood, P. M., Hordijk, P. L., Gerritsen, W. R. and van der Schoot, C. E. (2000) Adhesion molecules involved in transendothelial migration of human hematopoietic progenitor cells. Stem. Cells 18: 435-443.
36. Anghelina, M., Krishnan, P., Moldovan, L. and Moldovan, N. I. (2006) Monocytes/macrophages cooperate with progenitor cells during neovascularization and tissue repair: conversion of cell columns into fibrovascular bundles. Am. J. Pathol. 168: 529-541.
37. Moldovan, L., Moldovan, N. I., Sohn, R. H., Parikh, S. A. and Goldschmidt-Clermont, P. J. (2000) Redox changes of cultured endothelial cells and actin dynamics. Circ. Res. 86: 549-557.
38. Igarashi, K. and Miura, M. (2008) Inhibition of a radiation-induced senescence-like phenotype: a possible mechanism for potentially lethal damage repair in vascular endothelial cells. Radiat. Res. 170: 534-539.
39. Hida, K., Hida, Y., Amin, D. N., Flint, A. F., Panigrahy, D., Morton, C. C. and Klagsbrun, M. (2004) Tumor-associated endothelial cells with cytogenetic abnormalities. Cancer Res. 64: 8249-8255.
40. Hida, K. and Klagsbrun, M. (2005) A new perspective on tumor endothelial cells: unexpected chromosome and centrosome abnormalities. Cancer Res. 65: 2507-2510.
41. Amin, D. N., Hida, K., Bielenberg, D. R. and Klagsbrun, M. (2006) Tumor endothelial cells express epidermal growth factor receptor (EGFR) but not ErbB3 and are responsive to EGF and to EGFR kinase inhibitors. Cancer Res. 66: 2173-2180.
42. Yi, T., Yi, Z., Cho, S. G., Luo, J., Pandey, M. K., Aggarwal, B. B. and Liu, M. (2008) Gambogic acid inhibits angiogenesis and prostate tumor growth by suppressing vascular endothelial growth factor receptor 2 signaling. Cancer Res. 68: 1843-1850.
43. Hu, L., Roth, J. M., Brooks, P., Ibrahim, S. and Karpatkin, S. (2008) Twist is required for thrombin-induced tumor angiogenesis and growth. Cancer Res. 68: 4296-4302.
44. Falchetti, M. L., Mongiardi, M. P., Fiorenzo, P., Petrucci, G., Pierconti, F., D'Agnano, I., D'Alessandris, G., Alessandri, G., Gelati, M., Ricci-Vitiani, L., Maira, G., Larocca, L. M., Levi, A. and Pallini, R. (2008) Inhibition of telomerase in the endothelial cells disrupts tumor angiogenesis in glioblastoma xenografts. Int. J. Cancer 122(6): 1236-1242.
45. Tsuzuki, T. and Kawakami, Y. (2008) Tumor angiogenesis suppression by alpha-eleostearic acid, a linolenic acid isomer with a conjugated triene system, via peroxisome proliferator-activated receptor gamma. Carcinogenesis 29(4):797-806.
46. Dentelli, P., Rosso, A., Balsamo, A., Colmenares Benedetto, S., Zeoli, A., Pegoraro, M., Camussi, G., Pegoraro, L. and Brizzi, M. F. (2007) C-KIT, by interacting with the membrane-bound ligand, recruits endothelial progenitor cells to inflamed endothelium. Blood 109: 4264-4271.