PKCα-MAPK/ERK-phospholipase A2 signaling is required for human melanoma-enhanced brain endothelial cell proliferation and motility

Microvascular Research

Volumn 78, Issue 3, 2009, Pages 338-357

  Anfuso, Carmelina Daniela ^a   Giurdanella, Giovanni ^a   Motta, Carla ^a   Muriana, Stefano ^a   Lupo, Gabriella ^a   Ragusa, Nicola ^a   Alberghina, Mario ^a  

^a UNIVERSITY OF CATANIA   (Italy)

Author keywords

Ca++ independent phospholipase A2; Confocal microscopy; COX 2; Cytosolic phospholipase A2; Endothelial cells; ERK1 2; Melanomas; Protein kinase C alpha; Tumor angiogenesis

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; ARACHIDONIC ACID; CALCIUM INDEPENDENT PHOSPHOLIPASE A2; CYCLOOXYGENASE 2; CYTOSOLIC PHOSPHOLIPASE A2; ENZYME ANTIBODY; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOLIPASE A2; PROTEIN KINASE C ALPHA; WORTMANNIN; BLOCKING ANTIBODY;

ANGIOGENESIS; ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; BRAIN; CANCER CELL CULTURE; CELL ADHESION; CELL GROWTH; CELL INTERACTION; CELL METABOLISM; CELL MIGRATION; CELL MOTILITY; CELL PROLIFERATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ELECTROPORATION; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; MELANOMA; MELANOMA CELL; NONHUMAN; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; CELL LINE; CELL MEMBRANE; CELL MOTION; CULTURE MEDIUM; CYTOLOGY; DRUG EFFECT; ENZYMOLOGY; GENETICS; IMMUNOLOGY; METABOLISM; NEOVASCULARIZATION (PATHOLOGY); PHYSIOLOGY; TUMOR CELL LINE; VASCULAR ENDOTHELIUM; VASCULARIZATION;

RATTUS;

ANTIBODIES, BLOCKING; BRAIN; CELL LINE, TRANSFORMED; CELL LINE, TUMOR; CELL MEMBRANE; CELL MOVEMENT; CELL PROLIFERATION; CULTURE MEDIA, CONDITIONED; ELECTROPORATION; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; HUMANS; MAP KINASE SIGNALING SYSTEM; MELANOMA; NEOVASCULARIZATION, PATHOLOGIC; PHOSPHOLIPASES A2; PROTEIN KINASE C-ALPHA; SIGNAL TRANSDUCTION;

EID: 71549124683     PISSN: 00262862     EISSN: 10959319     Source Type: Journal    
DOI: 10.1016/j.mvr.2009.09.001     Document Type: Article

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